6,119
Views
127
CrossRef citations to date
0
Altmetric
Review

Mechanisms and context underlying the role of autophagy in cancer metastasis

ORCID Icon, ORCID Icon, &
Pages 1110-1128 | Received 15 Nov 2017, Accepted 21 Feb 2018, Published online: 04 Jun 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Dhrubo Ahmed Khan, Tonmoy Adhikary, Mst. Tania Sultana & Imran Ahamed Toukir. (2023) A comprehensive identification of potential molecular targets and small drugs candidate for melanoma cancer using bioinformatics and network-based screening approach. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-21.
Read now
Wenjie Sun, Junqiang Yan, Hongxia Ma, Jiannan Wu & Yongjiang Zhang. (2022) Autophagy-Dependent Ferroptosis-Related Signature is Closely Associated with the Prognosis and Tumor Immune Escape of Patients with Glioma. International Journal of General Medicine 15, pages 253-270.
Read now
Yanhong Xing, Xiangqing Wei, Yucheng Liu, Meng-Meng Wang, Zhongheng Sui, Xinyan Wang, Wucheng Zhu, Mengmei Wu, Chen Lu, Yuan-Hui Fei, Yi Jiang, Yang Zhang, Yuqing Wang, Feng Guo, Jun-Li Cao, Jiansong Qi & Wuyang Wang. (2022) Autophagy inhibition mediated by MCOLN1/TRPML1 suppresses cancer metastasis via regulating a ROS-driven TP53/p53 pathway. Autophagy 18:8, pages 1932-1954.
Read now
Chia-Cheng Miao, Wen Hwang, Ling-Yi Chu, Li-Hao Yang, Cam-Thu Ha, Pei-Yu Chen, Ming-Han Kuo, Sheng-Chieh Lin, Ya-Yu Yang, Shuang-En Chuang, Chia-Cherng Yu, Shien-Tung Pan, Mou-Chieh Kao, Chuang-Rung Chang & Yu-Ting Chou. (2022) LC3A-mediated autophagy regulates lung cancer cell plasticity. Autophagy 18:4, pages 921-934.
Read now
Song Yang, Gaohua Han, Quan Chen, Lei Yu, Peng Wang, Qi Zhang, Jiang Dong, Wei Zhang & Junxing Huang. (2021) Au-Pt Nanoparticle Formulation as a Radiosensitizer for Radiotherapy with Dual Effects. International Journal of Nanomedicine 16, pages 239-248.
Read now
Zhe Song, Nan Jia, Wei Li & Xiao-Yu Zhang. (2020) LINC01572 Regulates Cisplatin Resistance in Gastric Cancer Cells by Mediating miR-497-5p. OncoTargets and Therapy 13, pages 10877-10887.
Read now
Enyong Dai, Leng Han, Jiao Liu, Yangchun Xie, Guido Kroemer, Daniel J. Klionsky, Herbert J. Zeh, Rui Kang, Jing Wang & Daolin Tang. (2020) Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein. Autophagy 16:11, pages 2069-2083.
Read now

Articles from other publishers (120)

Iuliia Taskaeva, Anastasia Shatruk, Nataliya Bgatova, Alena Yeremina, Aleksander Trunov, Natalya Kononova & Valeriy Chernykh. (2023) Autophagy and vesicular trafficking in human uveal melanoma: A histopathological study. Microscopy Research and Technique 87:1, pages 122-132.
Crossref
Shweta Gulia, Prakash Chandra & Asmita Das. (2023) The Prognosis of Cancer Depends on the Interplay of Autophagy, Apoptosis, and Anoikis within the Tumor Microenvironment. Cell Biochemistry and Biophysics 81:4, pages 621-658.
Crossref
Wei Jiang, Zuoxiu Tie, Chi Yu, Yu Chen, Dan Liu & Bin Li. (2023) An engineered nanoplatform inhibiting energy metabolism and lysosomal activity of tumor cells to multiply cisplatin-based chemotherapy. Biomaterials 302, pages 122354.
Crossref
Amir Barzegar Behrooz, Marco Cordani, Massimo Donadelli & Saeid Ghavami. (2023) Metastatic outgrowth via the two-way interplay of autophagy and metabolism. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, pages 166824.
Crossref
Naveen Soni, Gargi Nandi, Megha Chaudhary & Bhawana Bissa. (2023) The role of ncRNA in the co-regulation of autophagy and exosome pathways during cancer progression. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1870:7, pages 119523.
Crossref
Huachen Song, Zitong Zhao, Liying Ma, Bailin ZhangYongmei Song. (2023) MiR-3653 blocks autophagy to inhibit epithelial–mesenchymal transition in breast cancer cells by targeting the autophagy-regulatory genes ATG12 and AMBRA1. Chinese Medical Journal.
Crossref
Luping Wang, Haote Han, Yue Feng, Jiahui Ma, Zhuo Han, Ruyi Li, Wei Zhu, Shouxin Li, Jingkui Tian & Lin Zhang. (2023) Capilliposide B inhibits the migration of prostate cancer by inducing autophagy through the ROS / AMPK / mTOR pathway . Phytotherapy Research 37:7, pages 2902-2914.
Crossref
Yu-Bo Shi, Shu-Yuan Chen & Ren-Bin Liu. (2023) The new insights into autophagy in thyroid cancer progression. Journal of Translational Medicine 21:1.
Crossref
Teow J. Phua. (2023) Understanding human aging and the fundamental cell signaling link in age-related diseases: the middle-aging hypovascularity hypoxia hypothesis. Frontiers in Aging 4.
Crossref
Aysooda Hosseinzadeh, Faezeh Poursoleiman, Akram Naghdipour Biregani & Ahmad Esmailzadeh. (2023) Flavonoids target different molecules of autophagic and metastatic pathways in cancer cells. Cancer Cell International 23:1.
Crossref
Hong-wei Wu, He-dan Chen, Ya-hong Chen, Xin-li Mao, Yu-yi Feng, Shao-wei Li & Xian-bin Zhou. (2023) The Effects of Programmed Cell Death of Mesenchymal Stem Cells on the Development of Liver Fibrosis. Stem Cells International 2023, pages 1-11.
Crossref
Javad Alizadeh, Mahboubeh Kavoosi, Navjit Singh, Shahrokh Lorzadeh, Amir Ravandi, Biniam Kidane, Naseer Ahmed, Fatima Mraiche, Michael R. Mowat & Saeid Ghavami. (2023) Regulation of Autophagy via Carbohydrate and Lipid Metabolism in Cancer. Cancers 15:8, pages 2195.
Crossref
Yuan Dong, Qiu Jin, Minghao Sun, Da Qi, Huinan Qu, Xinqi Wang & Chengshi Quan. (2023) CLDN6 inhibits breast cancer metastasis through WIP-dependent actin cytoskeleton-mediated autophagy. Journal of Experimental & Clinical Cancer Research 42:1.
Crossref
Ming Zhang, Linming Li, Suying Li, Zhifang Liu, Ning Zhang, Bin Sun, Zhengping Wang, Dianlong Jia, Min Liu & Qingpeng Wang. (2023) Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents. Journal of Medicinal Chemistry 66:5, pages 3393-3410.
Crossref
Tania Ciaglia, Vincenzo Vestuto, Alessia Bertamino, Rosario González-Muñiz & Isabel Gómez-Monterrey. (2023) On the modulation of TRPM channels: Current perspectives and anticancer therapeutic implications. Frontiers in Oncology 12.
Crossref
Xiaocong Pang, Xu He, Zhiwei Qiu, Hanxu Zhang, Ran Xie, Zhiyan Liu, Yanlun Gu, Nan Zhao, Qian Xiang & Yimin Cui. (2023) Targeting integrin pathways: mechanisms and advances in therapy. Signal Transduction and Targeted Therapy 8:1.
Crossref
Kun Luo, Shufeng Xu, Jing Zhao & Feifei Liu. (2022) Upregulation of lncRNA PINK1-AS Predicts the Distant Metastasis of Patients with Small Cell Lung Cancer. Molecular Biotechnology 65:1, pages 28-33.
Crossref
Jia-Lin Chen, Shu-Ting Liu, Shih-Ming Huang & Zhi-Fu Wu. (2022) Apoptosis, Proliferation, and Autophagy Are Involved in Local Anesthetic-Induced Cytotoxicity of Human Breast Cancer Cells. International Journal of Molecular Sciences 23:24, pages 15455.
Crossref
Wenjun Xu, Zhenjie Fu, Yuqin Xu, Man Hei Cheung, Yan Chen, Meiai Lin, Hang Wen, Hang Lv, Chun Liang, Jianshu Lou & Yitao Chen. (2022) pPe <italic>O</italic>p inhibits HGC-27 cell proliferation, migration and invasion by upregulating miR-30b-5p and down-regulating the Rac1/Cdc42 pathway. Acta Biochimica et Biophysica Sinica 54:12, pages 1897-1908.
Crossref
Zhiwei Sun, Doudou Liu, Bin Zeng, Qiting Zhao, Xiaoshuang Li, Hao Chen, Jianyu Wang & H. Rosie Xing. (2022) Sec23a inhibits the self-renewal of melanoma cancer stem cells via inactivation of ER-phagy. Cell Communication and Signaling 20:1.
Crossref
Chengxin Li, Qianqian Yuan, Gaoran Xu, Qian Yang, Jinxuan Hou, Lewei Zheng & Gaosong Wu. (2022) A seven-autophagy-related gene signature for predicting the prognosis of differentiated thyroid carcinoma. World Journal of Surgical Oncology 20:1.
Crossref
Qinglong Yan, Rui Sun, Zhifen Cui, Jichao Zhang, Yu Zhang, Qi Zhang, Shitai Zhu, Lihua Wang, Qian Li, Min Lu, Ying Zhu & Chunhai Fan. (2022) Nanodiamonds improve arsenic trioxide treatment of liver tumor by inhibiting metastasis in multiple organs. Nano Today 47, pages 101649.
Crossref
Yazhuo Wang, Yanan Ren, Na Li, Jing Zhao & Sufen Zhao. (2022) Rab11a promotes the malignant progression of ovarian cancer by inducing autophagy. Genes & Genomics 44:11, pages 1375-1384.
Crossref
Alin García-Miranda, Alejandra Garcia-Hernandez, Eduardo Castañeda-Saucedo, Napoleon Navarro-Tito & Paola Maycotte. (2022) Adipokines as Regulators of Autophagy in Obesity-Linked Cancer. Cells 11:20, pages 3230.
Crossref
Thunwa Binlateh, Nawapol Uppatcha, Jutamast Thepchai, Yanaphat Pleungtuk, Parinya Noisa, Pilaiwanwadee Hutamekalin & Paiboon Jitprasertwong. (2022) Cordycepin attenuates migration and invasion of HSC-4 oral squamous carcinoma cells through autophagy-dependent FAK/Akt and MMP2/MMP9 suppression. Journal of Dental Sciences 17:4, pages 1677-1688.
Crossref
Taotao Que, Bingyi Ren, Yizeng Fan, Tianjie Liu, Tao Hou, Weichao Dan, Bo Liu, Yi Wei, Yuzeshi Lei, Jin Zeng & Lei Li. (2022) Capsaicin inhibits the migration, invasion and EMT of renal cancer cells by inducing AMPK/mTOR-mediated autophagy. Chemico-Biological Interactions 366, pages 110043.
Crossref
Xiangpan Li, Qing Chen, Jingsheng Ao, Wenxin Lin, Liqin Qiu & Rihui Cao. (2022) Synthesis of novel 4,7-disubstituted quinoline derivatives as autophagy inducing agents via targeting stabilization of ATG5. Bioorganic Chemistry 127, pages 105998.
Crossref
Qiaxuan Li, Daipeng Xie, Lintong Yao, Hongrui Qiu, Peimeng You, Jialong Deng, Congsen Li, Weijie Zhan, Maotao Weng, Shaowei Wu, Fasheng Li, Yubo Zhou, Fanjun Zeng, Yong Zheng & Haiyu Zhou. (2022) Combining autophagy and immune characterizations to predict prognosis and therapeutic response in lung adenocarcinoma. Frontiers in Immunology 13.
Crossref
Qinying Liu, Yi Yang, Miaomiao Cheng, Fangting Cheng, Shanshan Chen, Qiuhong Zheng, Yang Sun & Li Chen. (2022) The marine natural product, dicitrinone B, induces apoptosis through autophagy blockade in breast cancer. International Journal of Molecular Medicine 50:4.
Crossref
Rohit Gundamaraju, Wenying Lu, Manash K. Paul, Niraj Kumar Jha, Piyush Kumar Gupta, Shreesh Ojha, Indranil Chattopadhyay, Pasupuleti Visweswara Rao & Saeid Ghavami. (2022) Autophagy and EMT in cancer and metastasis: Who controls whom?. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1868:9, pages 166431.
Crossref
Ting Yu, Shuai Ben, Ling Ma, Lu Jiang, Silu Chen, Yu Lin, Tao Chen, Shuwei Li & Lingjun Zhu. (2022) Genetic variants in autophagy-related gene ATG2B predict the prognosis of colorectal cancer patients receiving chemotherapy. Frontiers in Oncology 12.
Crossref
Jang Hee Han, Yong Keon Kim, Hakhyun Kim, Jooyoung Lee, Myung Joon Oh, Sang Bum Kim, Minjee Kim, Kook Hwan Kim, Hyun Ju Yoon, Myung‐Shik Lee, John D. Minna, Michael A. White & Hyun Seok Kim. (2022) Snail acetylation by autophagy‐derived acetyl‐coenzyme A promotes invasion and metastasis of KRAS ‐ LKB1 co‐mutated lung cancer cells . Cancer Communications 42:8, pages 716-749.
Crossref
Kamil Seyrek, Fabian Wohlfromm, Johannes Espe & Inna N. Lavrik. (2022) The cross-talk of autophagy and apoptosis in breast carcinoma: implications for novel therapies?. Biochemical Journal 479:14, pages 1581-1608.
Crossref
Josef Gillson, Yomna S. Abd El-Aziz, Lionel Y. W. Leck, Patric J. Jansson, Nick Pavlakis, Jaswinder S. Samra, Anubhav Mittal & Sumit Sahni. (2022) Autophagy: A Key Player in Pancreatic Cancer Progression and a Potential Drug Target. Cancers 14:14, pages 3528.
Crossref
Yunchi Zhu, Xin Liao, Tingyu Han, J.-Y. Chen, Chunpeng He & Zuhong Lu. (2022) Symbiodiniaceae microRNAs and their targeting sites in coral holobionts: A transcriptomics-based exploration. Genomics 114:4, pages 110404.
Crossref
Siyuan Qin, Bowen Li, Hui Ming, Edouard C. Nice, Bingwen Zou & Canhua Huang. (2022) Harnessing redox signaling to overcome therapeutic-resistant cancer dormancy. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877:4, pages 188749.
Crossref
Y. X. Shi, Z. W. Sun, D. L. Jia & H. B. Wang. (2022) Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1. Clinical and Translational Oncology 24:7, pages 1403-1412.
Crossref
Liwei Wang, Jiazhong Shi, Sha Liu, Yaqin Huang, Hua Ding, Baixiong Zhao, Yuting Liu, Wuxing Wang, Jin Yang & Zhiwen Chen. (2022) RAC3 Inhibition Induces Autophagy to Impair Metastasis in Bladder Cancer Cells via the PI3K/AKT/mTOR Pathway. Frontiers in Oncology 12.
Crossref
Amin Arif, Muhammad Babar Khawar, Rabia Mehmood, Muddasir Hassan Abbasi & Nadeem Sheikh. (2022) Dichotomous role of autophagy in cancer. Asian Biomedicine 16:3, pages 111-120.
Crossref
Kebai Ren, Jiao He, Yue Qiu, Zhuping Xu, Xuhui Wang, Jiaxin Li, Shuya Zang, Yiliang Yang, Jiaxin Li, Yang Long, Zhirong Zhang, Man Li & Qin He. (2022) A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis. Acta Biomaterialia 145, pages 185-199.
Crossref
Xupeng Yang, Meng Zhao, Zhihua Wu, Chuanrong Chen, Yanhua Zhang, Liting Wang, Qianqian Guo, Quan Wang, Shunshun Liang, Suxian Hu, Yourong Duan & Ying Sun. (2022) Nano-ultrasonic Contrast Agent for Chemoimmunotherapy of Breast Cancer by Immune Metabolism Reprogramming and Tumor Autophagy. ACS Nano 16:2, pages 3417-3431.
Crossref
Li-Yun Gong, Ting Tu, Jing Zhu, Ao-Ping Hu, Jun-Wei Song, Jing-Qiang Huang, Yi Yang, Zeyao Zhu & Yu Chen. (2022) Golgi phosphoprotein 3 induces autophagy and epithelial–mesenchymal transition to promote metastasis in colon cancer. Cell Death Discovery 8:1.
Crossref
Antonios N. Gargalionis, Kostas A. Papavassiliou, Efthimia K. Basdra & Athanasios G. Papavassiliou. (2022) mTOR Signaling Components in Tumor Mechanobiology. International Journal of Molecular Sciences 23:3, pages 1825.
Crossref
Anastasia D. Karampa, Anna C. Goussia, Georgios K. Glantzounis, Eleftheria M. Mastoridou, Nikolaos-Andreas T. Anastasopoulos & Antonia V. Charchanti. (2022) The Role of Macroautophagy and Chaperone-Mediated Autophagy in the Pathogenesis and Management of Hepatocellular Carcinoma. Cancers 14:3, pages 760.
Crossref
Song Su, Yan-Ting Shi, Yi Chu, Ming-Zuo Jiang, Nan Wu, Bing Xu, He Zhou, Jun-Chao Lin, Yi-Rong Jin, Xiao-Fei Li & Jie Liang. (2022) Sec62 promotes gastric cancer metastasis through mediating UPR-induced autophagy activation. Cellular and Molecular Life Sciences 79:2.
Crossref
Xiaolei Zhou, Li Li, Xin Guo, Chunxiao Zhang, Yanyan Du, Tianming Li, Kaiqing Tong, Chongyue Zhu & Zijin Wang. (2022) HBXIP induces anoikis resistance by forming a reciprocal feedback loop with Nrf2 to maintain redox homeostasis and stabilize Prdx1 in breast cancer. npj Breast Cancer 8:1.
Crossref
Jiujian Zheng, Chuan Cheng, Jie Xu, Peng Gao, Jianping Wang & Lifei Chen. (2022) miR-142-3p Regulates Tumor Cell Autophagy and Promotes Colon Cancer Progression by Targeting TP53INP2. Chemotherapy 67:2, pages 57-66.
Crossref
Peng Li, Yonghui Yang, Lu Qiu, Guangming Wan, Baomei Yuan, Yahong Wu, Yanfeng Gao & Guodong Li. (2022) 4-Hydroxyisoleucine inhibits tumor growth by triggering endoplasmic reticulum stress and autophagy. Current Research in Pharmacology and Drug Discovery 3, pages 100127.
Crossref
Yanhong Xing, Xiangqing Wei, Meng-meng Wang, Yucheng Liu, Zhongheng Sui, Xinyan Wang, Yang Zhang, Yuan-hui Fei, Yi Jiang, Chen Lu, Peng Zhang, Rong Chen, Nan Liu, Mengmei Wu, Lin Ding, Yuqing Wang, Feng Guo, Jun-li Cao, Jiansong Qi & Wuyang Wang. (2022) Stimulating TRPM7 suppresses cancer cell proliferation and metastasis by inhibiting autophagy. Cancer Letters 525, pages 179-197.
Crossref
Gracie Wee Ling Eng, Yilong Zheng, Dominic Wei Ting Yap, Andrea York Tiang Teo & Jit Kong Cheong. (2021) Autophagy and ncRNAs: Dangerous Liaisons in the Crosstalk between the Tumor and Its Microenvironment. Cancers 14:1, pages 20.
Crossref
Manuela Santarosa & Roberta Maestro. (2021) The Autophagic Route of E-Cadherin and Cell Adhesion Molecules in Cancer Progression. Cancers 13:24, pages 6328.
Crossref
Sarah J. Hernandez, Gianna Fote, Andrea M. Reyes-Ortiz, Joan S. Steffan & Leslie M. Thompson. (2021) Cooperation of cell adhesion and autophagy in the brain: Functional roles in development and neurodegenerative disease. Matrix Biology Plus 12, pages 100089.
Crossref
Raquel Gómez-Sintes & Esperanza Arias. (2021) Chaperone-mediated autophagy and disease: Implications for cancer and neurodegeneration. Molecular Aspects of Medicine 82, pages 101025.
Crossref
Feifei Tan & Zhongyin Zhou. (2021) Autophagy-related lncRNA and its related mechanism in colon adenocarcinoma. Oncology and Translational Medicine 7:6, pages 305-313.
Crossref
Bi-Chun Chen, Jun-Jian Lu, Ning Jiang, Xiu-Rong Ma, Rong-Tao Li & Rui-Rong Ye. (2021) Synthesis, characterization and antitumor mechanism investigation of ruthenium(II) polypyridyl complexes with artesunate moiety. JBIC Journal of Biological Inorganic Chemistry 26:8, pages 909-918.
Crossref
Juan Wang, Guoxiang Liu, Xiaojuan Li, Mengjie Huangfu, Yisa Liu, Xumei Li, Dan Yu, Luwei Zhou & Xu Chen. (2021) Curcumol simultaneously induces both apoptosis and autophagy in human nasopharyngeal carcinoma cells. Phytotherapy Research 35:12, pages 7004-7017.
Crossref
Yuchen Lei & Daniel J. Klionsky. (2021) The Emerging Roles of Autophagy in Human Diseases. Biomedicines 9:11, pages 1651.
Crossref
Pei-Ru Jin, Yen-Nhi Ngoc Ta, I-Ting Chen, Yan-Ning Yu, Hsin Tzu Hsieh, Van-Anh Thi Nguyen, Shang-Ying Hsieh, Tiffaney Hsia, Hao Liu, Chan-Wei Hsu, Jeng-Liang Han & Yunching Chen. (2021) Cinchona Alkaloid-Inspired Urea-Containing Autophagy Inhibitor Shows Single-Agent Anticancer Efficacy. Journal of Medicinal Chemistry 64:19, pages 14513-14525.
Crossref
Bowen Li, Yichun Huang, Hui Ming, Edouard C. Nice, Rongrong Xuan & Canhua Huang. (2021) Redox Control of the Dormant Cancer Cell Life Cycle. Cells 10:10, pages 2707.
Crossref
Daniel J Klionsky, Giulia Petroni, Ravi K Amaravadi, Eric H Baehrecke, Andrea Ballabio, Patricia Boya, José Manuel Bravo‐San Pedro, Ken Cadwell, Francesco Cecconi, Augustine M K Choi, Mary E Choi, Charleen T Chu, Patrice Codogno, Maria Isabel Colombo, Ana Maria Cuervo, Vojo Deretic, Ivan Dikic, Zvulun Elazar, Eeva‐Liisa Eskelinen, Gian Maria Fimia, David A Gewirtz, Douglas R Green, Malene Hansen, Marja Jäättelä, Terje Johansen, Gábor Juhász, Vassiliki Karantza, Claudine Kraft, Guido Kroemer, Nicholas T Ktistakis, Sharad Kumar, Carlos Lopez‐Otin, Kay F Macleod, Frank Madeo, Jennifer Martinez, Alicia Meléndez, Noboru Mizushima, Christian Münz, Josef M Penninger, Rushika M Perera, Mauro Piacentini, Fulvio Reggiori, David C Rubinsztein, Kevin M Ryan, Junichi Sadoshima, Laura Santambrogio, Luca Scorrano, Hans‐Uwe Simon, Anna Katharina Simon, Anne Simonsen, Alexandra Stolz, Nektarios Tavernarakis, Sharon A Tooze, Tamotsu Yoshimori, Junying Yuan, Zhenyu Yue, Qing Zhong, Lorenzo Galluzzi & Federico Pietrocola. (2021) Autophagy in major human diseases. The EMBO Journal 40:19.
Crossref
Xiao Ling, Jun Lu, Jun Yang, Hanjun Qin, Xingqi Zhao, Pengyu Zhou, Shaoyi Zheng & Peng Zhu. (2021) Non-Coding RNAs: Emerging Therapeutic Targets in Spinal Cord Ischemia–Reperfusion Injury. Frontiers in Neurology 12.
Crossref
Vladimir Mulens-Arias. (2021) Dissecting the Inorganic Nanoparticle-Driven Interferences on Adhesome Dynamics. Journal of Nanotheranostics 2:3, pages 174-195.
Crossref
Bowen Yang, Fu Peng, Yu Zhang, Xuan Wang, Shengqi Wang, Yifeng Zheng, Juping Zhang, Yihao Zeng, Neng Wang, Cheng Peng & Zhiyu Wang. (2021) Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy. Phytomedicine 90, pages 153628.
Crossref
Yasaswi Gayatri Mishra & Bramanandam Manavathi. (2021) Focal adhesion dynamics in cellular function and disease. Cellular Signalling 85, pages 110046.
Crossref
Guanyue Su, Tang Feng, Tong Pei, Fan Yang, Denglian Sun, Hongchi Yu, Xiaoli Wang, Wenbo Gao, Jia He, Yang Shen & Xiaoheng Liu. (2021) Autophagy modulates FSS‐induced epithelial–mesenchymal transition in hepatocellular carcinoma cells. Molecular Carcinogenesis 60:9, pages 607-619.
Crossref
Xiaojie Tan, Jiahui Fu, Zhaoxin Yuan, Lingjuan Zhu & Leilei Fu. (2021) ACNPD: The Database for Elucidating the Relationships Between Natural Products, Compounds, Molecular Mechanisms, and Cancer Types. Frontiers in Pharmacology 12.
Crossref
Mengmei Zhu, Tianzhen Hua, Tao Ouyang, Huofu Qian & Bing Yu. (2021) Applications of Mesenchymal Stem Cells in Liver Fibrosis: Novel Strategies, Mechanisms, and Clinical Practice. Stem Cells International 2021, pages 1-17.
Crossref
Heyang Cui, Yongjia Weng, Ning Ding, Chen Cheng, Longlong Wang, Yong Zhou, Ling Zhang, Yongping Cui & Weimin Zhang. (2021) Autophagy-Related Three-Gene Prognostic Signature for Predicting Survival in Esophageal Squamous Cell Carcinoma. Frontiers in Oncology 11.
Crossref
Doudou Liu, Zhiwei Sun, Ting Ye, Jingyuan Li, Bin Zeng, Qiting Zhao, Jianyu Wang & Hongmei Rosie Xing. (2021) The mitochondrial fission factor FIS1 promotes stemness of human lung cancer stem cells via mitophagy. FEBS Open Bio 11:7, pages 1997-2007.
Crossref
Chao-Yue Sun, Di Cao, Qian-Nan Ren, Shan-Shan Zhang, Ning-Ning Zhou, Shi-Juan Mai, Bing Feng & Hui-Yun Wang. (2021) Combination Treatment With Inhibitors of ERK and Autophagy Enhances Antitumor Activity of Betulinic Acid in Non–small-Cell Lung Cancer In Vivo and In Vitro. Frontiers in Pharmacology 12.
Crossref
Teow J. Phua. (2021) The Etiology and Pathophysiology Genesis of Benign Prostatic Hyperplasia and Prostate Cancer: A New Perspective. Medicines 8:6, pages 30.
Crossref
Liwei Wu, Zilu Wen, Yanzheng Song & Lin Wang. (2021) A novel autophagy‐related lncRNA survival model for lung adenocarcinoma. Journal of Cellular and Molecular Medicine 25:12, pages 5681-5690.
Crossref
Rui Cao, Bo Ma, Gang Wang, Yaoyi Xiong, Ye Tian & Lushun Yuan. (2021) Identification of autophagy‐related genes signature predicts chemotherapeutic and immunotherapeutic efficiency in bladder cancer (BLCA). Journal of Cellular and Molecular Medicine 25:12, pages 5417-5433.
Crossref
Zixiang Yuan, Jun Chen, Qin Zhou, Ao Liu, Zeming Qiang, Min Fang, Man Chen, Yan Feng, Haizhu Yu, Xiuli Yang & Xiangming Meng. (2021) A lysosomal polarity-specific two-photon fluorescent probe for visualization of autophagy. Chinese Chemical Letters 32:5, pages 1803-1808.
Crossref
Shiming Yang, Yaping Zhou, Xiangxin Zhang, Lu Wang, Jianfeng Fu, Xiaotong Zhao & Liu Yang. (2021) The prognostic value of an autophagy-related lncRNA signature in hepatocellular carcinoma. BMC Bioinformatics 22:1.
Crossref
Chaoting Zhou, Alex Heng Li, Shan Liu & Hong Sun. (2021) Identification of an 11-Autophagy-Related-Gene Signature as Promising Prognostic Biomarker for Bladder Cancer Patients. Biology 10:5, pages 375.
Crossref
Luis Gustavo Saboia Ponte, Isadora Carolina Betim Pavan, Mariana Camargo Silva Mancini, Luiz Guilherme Salvino da Silva, Ana Paula Morelli, Matheus Brandemarte Severino, Rosangela Maria Neves Bezerra & Fernando Moreira Simabuco. (2021) The Hallmarks of Flavonoids in Cancer. Molecules 26:7, pages 2029.
Crossref
Courtney E. McAleese, Chandra Choudhury, Neville J. Butcher & Rodney F. Minchin. (2021) Hypoxia-mediated drug resistance in breast cancers. Cancer Letters 502, pages 189-199.
Crossref
Song Hu, Jie Yin, Shan Yan, Ping Hu, Jianzheng Huang, Geng Zhang, Fuqian Wang, Qingyi Tong & Yonghui Zhang. (2021) Chaetocochin J, an epipolythiodioxopiperazine alkaloid, induces apoptosis and autophagy in colorectal cancer via AMPK and PI3K/AKT/mTOR pathways. Bioorganic Chemistry 109, pages 104693.
Crossref
Maria Paz Hernández-Cáceres, Leslie Munoz, Javiera M. Pradenas, Francisco Pena, Pablo Lagos, Pablo Aceiton, Gareth I. Owen, Eugenia Morselli, Alfredo Criollo, Andrea Ravasio & Cristina Bertocchi. (2021) Mechanobiology of Autophagy: The Unexplored Side of Cancer. Frontiers in Oncology 11.
Crossref
Jiankun Zang, Yousheng Wu, Xuanlin Su, Tianyuan Zhang, Xionglin Tang, Dan Ma, Yufeng Li, Yanfang Liu, Ze’an Weng, Xuanzhuo Liu, Chi Kwan Tsang, Anding Xu & Dan Lu. (2021) Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for Neuroprotection Against Ischemic Stroke. Frontiers in Cell and Developmental Biology 8.
Crossref
Eswara Murali Satyavarapu, Shalini Nath & Chitra Mandal. (2021) Desialylation of Atg5 by sialidase (Neu2) enhances autophagosome formation to induce anchorage-dependent cell death in ovarian cancer cells. Cell Death Discovery 7:1.
Crossref
Tatsuya Hattori, Yoshinori Takahashi, Longgui Chen, Zhenyuan Tang, Carson A. Wills, Xinwen Liang & Hong-Gang Wang. (2020) Targeting the ESCRT-III component CHMP2A for noncanonical Caspase-8 activation on autophagosomal membranes. Cell Death & Differentiation 28:2, pages 657-670.
Crossref
Abeer Alharbi, Yuxuan Zhang & John Parrington. (2021) Deciphering the Role of Ca2+ Signalling in Cancer Metastasis: From the Bench to the Bedside. Cancers 13:2, pages 179.
Crossref
Jia-Qi Sheng, Mu-Ru Wang, Dan Fang, Lian Liu, Wen-Jie Huang, De-An Tian, Xing-Xing He & Pei-Yuan Li. (2021) LncRNA NBR2 inhibits tumorigenesis by regulating autophagy in hepatocellular carcinoma. Biomedicine & Pharmacotherapy 133, pages 111023.
Crossref
Yu Gu, Songtao Lai, Yang Dong, Hao Fu, Liwei Song, Tianxiang Chen, Yourong Duan & Zhen Zhang. (2020) AZD9291 Resistance Reversal Activity of a pH‐Sensitive Nanocarrier Dual‐Loaded with Chloroquine and FGFR1 Inhibitor in NSCLC. Advanced Science 8:2.
Crossref
Zahra Zare & Maryam Teimouri. (2020) The therapeutic effects of Physalis alkekengi hydroalcoholic extract on estrogen receptor-positive breast cancer mice model: possible role of autophagy in this therapeutic response . Journal of Shahrekord University of Medical Sciences 22:4, pages 181-186.
Crossref
Cai Yang, Hongxiang Mei, Liang Peng, Fulin Jiang, Bingjie Xie & Juan Li. (2020) Prognostic Correlation of an Autophagy-Related Gene Signature in Patients with Head and Neck Squamous Cell Carcinoma. Computational and Mathematical Methods in Medicine 2020, pages 1-23.
Crossref
Neng Wang, Gulizeba Muhetaer, Xiaotong Zhang, Bowen Yang, Caiwei Wang, Yu Zhang, Xuan Wang, Juping Zhang, Shengqi Wang, Yifeng Zheng, Fengxue Zhang & Zhiyu Wang. (2020) Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling. Frontiers in Pharmacology 11.
Crossref
Charlotte Nicole Hill, Maria Paz Hernández-Cáceres, Catalina Asencio, Begoña Torres, Benjamin Solis & Gareth I. Owen. (2020) Deciphering the Role of the Coagulation Cascade and Autophagy in Cancer-Related Thrombosis and Metastasis. Frontiers in Oncology 10.
Crossref
Doh Yu Hwang, Ju-In Eom, Ji Eun Jang, Hoi-Kyung Jeung, Haerim Chung, Jin Seok Kim, June-Won Cheong & Yoo Hong Min. (2020) ULK1 inhibition as a targeted therapeutic strategy for FLT3-ITD-mutated acute myeloid leukemia. Journal of Experimental & Clinical Cancer Research 39:1.
Crossref
Zhenting Huang, Qian Yan, Yangyang Wang, Qian Zou, Jing Li, Zhou Liu & Zhiyou Cai. (2020) Role of Mitochondrial Dysfunction in the Pathology of Amyloid-β. Journal of Alzheimer's Disease 78:2, pages 505-514.
Crossref
Binita Zipporah E, Bamadeb Patra, Kavitha Govarthanan, Rajesh Yadav, Sheila Mohan, Pavithra Shyamsunder & Rama Shanker Verma. (2020) Defective cell proliferation is an attribute of overexpressed Notch1 receptor and impaired autophagy in Fanconi Anemia. Genomics 112:6, pages 4628-4639.
Crossref
Hsin‐Han Hou, Huei‐Jyuan Pan, Wei‐Yu Liao, Chau‐Hwang Lee & Chong‐Jen Yu. (2020) Autophagy in fibroblasts induced by cigarette smoke extract promotes invasion in lung cancer cells. International Journal of Cancer 147:9, pages 2587-2596.
Crossref
Jose G. Alvarez-Meythaler, Yoelsis Garcia-Mayea, Cristina Mir, Hiroshi Kondoh & Matilde E. LLeonart. (2020) Autophagy Takes Center Stage as a Possible Cancer Hallmark. Frontiers in Oncology 10.
Crossref
Huilin Zhang & Bingjian Lu. (2020) The Roles of ceRNAs-Mediated Autophagy in Cancer Chemoresistance and Metastasis. Cancers 12:10, pages 2926.
Crossref
Rodolfo Chavez-Dominguez, Mario Perez-Medina, Jose S. Lopez-Gonzalez, Miriam Galicia-Velasco & Dolores Aguilar-Cazares. (2020) The Double-Edge Sword of Autophagy in Cancer: From Tumor Suppression to Pro-tumor Activity. Frontiers in Oncology 10.
Crossref
Wei Xiong, Yong Liao, Ji-Yong Qin, Wen-Hui Li & Zhao-You Tang. (2020) Adverse effects of chemoradiotherapy on invasion and metastasis of tumor cells. Genes & Diseases 7:3, pages 351-358.
Crossref
Zeinab Nouri, Sajad Fakhri, Keyvan Nouri, Carly E. Wallace, Mohammad Hosein Farzaei & Anupam Bishayee. (2020) Targeting Multiple Signaling Pathways in Cancer: The Rutin Therapeutic Approach. Cancers 12:8, pages 2276.
Crossref
Zhongtao Li, Jiaoqing Tang, Hongfeng Wu, Zhixin Ling, Siyu Chen, Yong Zhou, Bo Guo, Xiao Yang, Xiangdong Zhu, Lin Wang, Chongqi Tu & Xingdong Zhang. (2020) A systematic assessment of hydroxyapatite nanoparticles used in the treatment of melanoma. Nano Research 13:8, pages 2106-2117.
Crossref
Kun Yang, Jiarui Cai, Miao Pan, Qian Sun & Chao Sun. (2020) Mark4 Inhibited the Browning of White Adipose Tissue by Promoting Adipocytes Autophagy in Mice. International Journal of Molecular Sciences 21:8, pages 2752.
Crossref
Manish Adhikari, Bhawana Adhikari, Bhagirath Ghimire, Sanjula Baboota & Eun Ha Choi. (2020) Cold Atmospheric Plasma and Silymarin Nanoemulsion Activate Autophagy in Human Melanoma Cells. International Journal of Molecular Sciences 21:6, pages 1939.
Crossref
Li Yan, Lian-Zhao Wang, Ran Xiao, Rui Cao, Bo Pan, Xiao-Yan Lv, Hu Jiao, Qiang Zhuang, Xue-Jian Sun & Yuan-Bo Liu. (2020) Inhibition of microRNA-21-5p reduces keloid fibroblast autophagy and migration by targeting PTEN after electron beam irradiation. Laboratory Investigation 100:3, pages 387-399.
Crossref
Li Liu, Lu Yan, Ning Liao, Wan-Qin Wu & Jun-Ling Shi. (2020) A Review of ULK1-Mediated Autophagy in Drug Resistance of Cancer. Cancers 12:2, pages 352.
Crossref
Kelie Chen, Dexin Yang, Fan Zhao, Shengchao Wang, Yao Ye, Wenjie Sun, Haohua Lu, Zhi Ruan, Jinming Xu, Tianru Wang, Guang Lu, Liming Wang, Yu Shi, Honghe Zhang, Han Wu, Weiguo Lu, Han-Ming Shen, Dajing Xia & Yihua Wu. (2020) Autophagy and Tumor Database: ATdb, a novel database connecting autophagy and tumor. Database 2020.
Crossref
Shi Quan Wong, Anita V. Kumar, Joslyn Mills & Louis R. Lapierre. 2020. Autophagy in health and disease. Autophagy in health and disease 325 373 .
Siddavaram Nagini, Palrasu Manikandan & Rama Rao Malla. 2020. Autophagy in tumor and tumor microenvironment. Autophagy in tumor and tumor microenvironment 223 247 .
Jing Hou, Zhipeng Han, Naping Zhao & Lixin Wei. 2020. Autophagy: Biology and Diseases. Autophagy: Biology and Diseases 315 338 .
Hongtao Zhu, Xiaoling Gan, Xingwei Jiang, Shuai Diao, Huan Wu & Jianguo Hu. (2019) ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2. Journal of Experimental & Clinical Cancer Research 38:1.
Crossref
Fan Feng, Moxuan Zhang, Chuanchao Yang, Xueyuan Heng & Xiujie Wu. (2019) The dual roles of autophagy in gliomagenesis and clinical therapy strategies based on autophagic regulation mechanisms. Biomedicine & Pharmacotherapy 120, pages 109441.
Crossref
Rafael Luis Bressani Lino, Patty Karina dos Santos, Graziéle Fernanda Deriggi Pisani, Wanessa Fernanda Altei, Marcia Regina Cominetti & Heloisa Sobreiro Selistre-de-Araújo. (2019) Alphavbeta3 integrin blocking inhibits apoptosis and induces autophagy in murine breast tumor cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1866:12, pages 118536.
Crossref
Tsai‐Yi Tseng, Hui‐Ling Chiou, Chiao‐Wen Lin, Yong‐Syuan Chen, Li‐Sung Hsu, Chien‐Hsing Lee & Yi‐Hsien Hsieh. (2019) Repression of metastasis‐associated protein 2 for inhibiting metastasis of human oral cancer cells by promoting the p‐cofilin‐1/ LC3‐II expression. Journal of Oral Pathology & Medicine 48:10, pages 959-966.
Crossref
Dorota Ciołczyk-Wierzbicka, Marta Zarzycka, Dorota Gil & Piotr Laidler. (2019) mTOR inhibitor Everolimus-induced apoptosis in melanoma cells. Journal of Cell Communication and Signaling 13:3, pages 357-368.
Crossref
Xueyan Li, Li Meng, Feng Wang, Xiaojie Hu & Youcheng Yu. (2018) Sodium fluoride induces apoptosis and autophagy via the endoplasmic reticulum stress pathway in MC3T3-E1 osteoblastic cells. Molecular and Cellular Biochemistry 454:1-2, pages 77-85.
Crossref
Beth Levine & Guido Kroemer. (2019) Biological Functions of Autophagy Genes: A Disease Perspective. Cell 176:1-2, pages 11-42.
Crossref
Justyna Gil, David Ramsey, Pawel Pawlowski, Elzbieta Szmida, Przemyslaw Leszczynski, Marek Bebenek & Maria M. Sasiadek. (2018) The Influence of Tumor Microenvironment on ATG4D Gene Expression in Colorectal Cancer Patients. Medical Oncology 35:12.
Crossref
Christopher M. Dower, Neema Bhat, Melat T. Gebru, Longgui Chen, Carson A. Wills, Barbara A. Miller & Hong-Gang Wang. (2018) Targeted Inhibition of ULK1 Promotes Apoptosis and Suppresses Tumor Growth and Metastasis in Neuroblastoma. Molecular Cancer Therapeutics 17:11, pages 2365-2376.
Crossref
Jasmina Makarević, Jochen Rutz, Eva Juengel, Sebastian Maxeiner, Jens Mani, Stefan Vallo, Igor Tsaur, Frederik Roos, Felix Chun & Roman Blaheta. (2018) HDAC Inhibition Counteracts Metastatic Re-Activation of Prostate Cancer Cells Induced by Chronic mTOR Suppression. Cells 7:9, pages 129.
Crossref
Yasuyoshi Miyata, Tomohiro ScienMatsuoces, Kyohei Araki, Yuichiro Nakamura, Yuji Sagara, Kojiro Ohba & Hideki Sakai. (2018) Anticancer Effects of Green Tea and the Underlying Molecular Mechanisms in Bladder Cancer. Medicines 5:3, pages 87.
Crossref
Qinglong Yan, Rui Sun, Zhifen Cui, Jichao Zhang, Yu Zhang, Qi Zhang, Shitai Zhu, Lihua Wang, Qian Li, Min Lu, Ying Zhu & Chunhai Fan. (2022) Nanodiamonds Improve Arsenic Trioxide Treatment of Liver Tumor by Inhibiting Metastasis in Multiple Organs. SSRN Electronic Journal.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.