Autophagy, Volume 14, Issue 7 (2018)

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Autophagy, Volume 14, Issue 7 (2018)

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Editor’s Corner

Editorial
CCPG1 is a noncanonical autophagy cargo receptor essential for reticulophagy and pancreatic ER proteostasis
Vikramjit Lahiri & Daniel J. Klionsky
Pages: 1107-1109
Published online: 16 Oct 2018
AbstractforCCPG1 is a noncanonical autophagy cargo receptor essential for reticulophagy and pancreatic ER proteostasis | Full Text | References | PDF (419.9 KB)
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Review

Review
Mechanisms and context underlying the role of autophagy in cancer metastasis
Christopher M. Dower, Carson A. Wills, Steven M. Frisch & Hong-Gang Wang
Pages: 1110-1128
Published online: 04 Jun 2018
AbstractforMechanisms and context underlying the role of autophagy in cancer metastasis | Full Text | References | PDF (1.9 MB)
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Research Paper–Basic Science

Article
Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion
Elisabet Barbero-Camps, Vicente Roca-Agujetas, Isabel Bartolessis, Cristina de Dios, Jose C. Fernández-Checa, Montserrat Marí, Albert Morales, Tobias Hartmann & Anna Colell
Pages: 1129-1154
Published online: 04 Jun 2018
AbstractforCholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion | Full Text | References | PDF (3.3 MB) | Supplemental
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Autophagic Punctum

Article Commentary
An atypical BAR domain protein in autophagy
Hana Popelka, Daniel J. Klionsky & Michael J. Ragusa
Pages: 1155-1156
Published online: 25 May 2018
AbstractforAn atypical BAR domain protein in autophagy | Full Text | PDF (391.1 KB)
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Article Commentary
Defective autophagy degradation and abnormal tight junction-associated signaling drive epithelial dysfunction in cystinosis
Alessandro Luciani, Beatrice Paola Festa, Zhiyong Chen & Olivier Devuyst
Pages: 1157-1159
Published online: 28 May 2018
AbstractforDefective autophagy degradation and abnormal tight junction-associated signaling drive epithelial dysfunction in cystinosis | Full Text | PDF (548.9 KB)
  • 1865 Views
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Article Commentary
A ubiquitin-dependent mitophagy complex maintains mitochondrial function and insulin secretion in beta cells
Gemma Pearson & Scott A. Soleimanpour
Pages: 1160-1161
Published online: 25 May 2018
AbstractforA ubiquitin-dependent mitophagy complex maintains mitochondrial function and insulin secretion in beta cells | Full Text | PDF (494 KB)
  • 1922 Views
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Article Commentary
Aspirin—another caloric-restriction mimetic
Federico Pietrocola, Francesca Castoldi, Maria Chiara Maiuri & Guido Kroemer
Pages: 1162-1163
Published online: 18 Jul 2018
AbstractforAspirin—another caloric-restriction mimetic | Full Text | PDF (464.5 KB)
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Research Paper - Basic Science

Article
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke
Bing Han, Yuan Zhang, Yanhong Zhang, Ying Bai, Xufeng Chen, Rongrong Huang, Fangfang Wu, Shuo Leng, Jie Chao, John H. Zhang, Gang Hu & Honghong Yao
Pages: 1164-1184
Published online: 20 Jul 2018
AbstractforNovel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke | Full Text | References | PDF (3.3 MB) | Supplemental
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Article
Silica nanoparticles induce autophagosome accumulation via activation of the EIF2AK3 and ATF6 UPR pathways in hepatocytes
Ji Wang, Yang Li, Junchao Duan, Man Yang, Yang Yu, Lin Feng, Xiaozhe Yang, Xianqing Zhou, Zhendong Zhao & Zhiwei Sun
Pages: 1185-1200
Published online: 20 Jul 2018
AbstractforSilica nanoparticles induce autophagosome accumulation via activation of the EIF2AK3 and ATF6 UPR pathways in hepatocytes | Full Text | References | PDF (3.7 MB) | Supplemental
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Article
Poliovirus induces autophagic signaling independent of the ULK1 complex
Angel Corona Velazquez, Abigail K. Corona, Kathryn A. Klein & William T. Jackson
Pages: 1201-1213
Published online: 20 Jul 2018
AbstractforPoliovirus induces autophagic signaling independent of the ULK1 complex | Full Text | References | PDF (2.2 MB) | Supplemental
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Article
Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer
Syn Kok Yeo, Ritama Paul, Michael Haas, Chenran Wang & Jun-Lin Guan
Pages: 1214-1225
Published online: 20 Jul 2018
AbstractforImproved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer | Full Text | References | PDF (2.2 MB) | Supplemental
  • 2021 Views
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Article
Inhibiting autophagy reduces retinal degeneration caused by protein misfolding
Jingyu Yao, Yaoyan Qiu, Eric Frontera, Lin Jia, Naheed W. Khan, Daniel J. Klionsky, Thomas A. Ferguson, Debra A. Thompson & David N. Zacks
Pages: 1226-1238
Published online: 13 Jul 2018
AbstractforInhibiting autophagy reduces retinal degeneration caused by protein misfolding | Full Text | References | PDF (2.6 MB) | Supplemental
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Article
ROS is the major player in regulating altered autophagy and lifespan in sin-3 mutants of C. elegans
Meenakshi Sharma, Renu Pandey & Daman Saluja
Pages: 1239-1255
Published online: 20 Jul 2018
AbstractforROS is the major player in regulating altered autophagy and lifespan in sin-3 mutants of C. elegans | Full Text | References | PDF (2.8 MB) | Supplemental
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Toolbox

Article
A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo
Liam D. Cassidy, Andrew RJ. Young, Pedro A. Pérez-Mancera, Birgit Nimmervoll, Adil Jaulim, Hung-Chang Chen, Dominick J. O. McIntyre, Rebecca Brais, Thomas Ricketts, Simon Pacey, Maike De La Roche, Richard J. Gilbertson, David C. Rubinsztein & Masashi Narita
Pages: 1256-1266
Published online: 12 Jul 2018
AbstractforA novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo | Full Text | References | PDF (2.1 MB) | Supplemental
  • 3957 Views
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Open Access

Commentary

Article Commentary
CMA restricted to mammals and birds: myth or reality?
Laury Lescat, Amaury Herpin, Brigitte Mourot, Vincent Véron, Yann Guiguen, Julien Bobe & Iban Seiliez
Pages: 1267-1270
Published online: 20 Jul 2018
AbstractforCMA restricted to mammals and birds: myth or reality? | Full Text | References | PDF (1.3 MB) | Supplemental
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Autophagic Punctum

Article Commentary
Cdk5-mediated Acn/Acinus phosphorylation regulates basal autophagy independently of metabolic stress
Nilay Nandi & Helmut Krämer
Pages: 1271-1272
Published online: 21 May 2018
AbstractforCdk5-mediated Acn/Acinus phosphorylation regulates basal autophagy independently of metabolic stress | Full Text | PDF (478.8 KB)
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Article Commentary
Targeting autophagy for therapy of hyperammonemia
Leandro R. Soria & Nicola Brunetti-Pierri
Pages: 1273-1275
Published online: 23 Jul 2018
AbstractforTargeting autophagy for therapy of hyperammonemia | Full Text | PDF (454.3 KB)
  • 1678 Views
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Article Commentary
Age-associated and tissue-specific decline in autophagic activity in the nematode C. elegans
Jessica T. Chang & Malene Hansen
Pages: 1276-1277
Published online: 28 May 2018
AbstractforAge-associated and tissue-specific decline in autophagic activity in the nematode C. elegans | Full Text | PDF (499.9 KB)
  • 1750 Views
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Commentary

Article Commentary
Metformin reduces TRIB3 expression and restores autophagy flux: an alternative antitumor action
Ke Li, Ting-ting Zhang, Fang Hua & Zhuo-wei Hu
Pages: 1278-1279
Published online: 20 Jul 2018
AbstractforMetformin reduces TRIB3 expression and restores autophagy flux: an alternative antitumor action | Full Text | PDF (410.4 KB)
  • 2216 Views
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Article Commentary
Phasing out the bad—How SQSTM1/p62 sequesters ubiquitinated proteins for degradation by autophagy
Gabriele Zaffagnini, Adriana Savova, Alberto Danieli, Julia Romanov, Shirley Tremel, Michael Ebner, Thomas Peterbauer, Martin Sztacho, Riccardo Trapannone, Abul K. Tarafder, Carsten Sachse & Sascha Martens
Pages: 1280-1282
Published online: 20 Jul 2018
AbstractforPhasing out the bad—How SQSTM1/p62 sequesters ubiquitinated proteins for degradation by autophagy | Full Text | PDF (1 MB)
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Article Commentary
The anti-apoptotic ubiquitin conjugating enzyme BIRC6/BRUCE regulates autophagosome-lysosome fusion
Fumiyo Ikeda
Pages: 1283-1284
Published online: 20 Jul 2018
AbstractforThe anti-apoptotic ubiquitin conjugating enzyme BIRC6/BRUCE regulates autophagosome-lysosome fusion | Full Text | References | PDF (473.6 KB)
  • 1983 Views
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Article Commentary
Denitrosylate and live longer: how ADH5/GSNOR links mitophagy to aging
Salvatore Rizza & Giuseppe Filomeni
Pages: 1285-1287
Published online: 20 Jul 2018
AbstractforDenitrosylate and live longer: how ADH5/GSNOR links mitophagy to aging | Full Text | References | PDF (538.1 KB)
  • 1861 Views
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Article Commentary
EIF5A mediates autophagy via translation of ATG3
Lisa B. Frankel
Pages: 1288-1289
Published online: 20 Jul 2018
AbstractforEIF5A mediates autophagy via translation of ATG3 | Full Text | References | PDF (455.4 KB)
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Corrigendum

Correction
Corrigendum
Page: 1290
Published online: 20 Jul 2018
CitationforCorrigendum | Full Text | PDF (288.2 KB)
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