https://orcid.org/0000-0002-1032-5808
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Daniel W. Woodall, Thomas M. Dillon, Kevin Kalenian, Rupa Padaki, Scott Kuhns, David J. Semin & Pavel V. Bondarenko. (2022) Non-targeted characterization of attributes affecting antibody-FcγRIIIa V158 (CD16a) binding via online affinity chromatography-mass spectrometry. mAbs 14:1.
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Muhammad Safwan Akram, Neelam Pery, Lucy Butler, Muhammad Imtiaz Shafiq, Nayab Batool, Muhammad Fayyaz ur Rehman, Luke G. Grahame-Dunn & Ali K. Yetisen. (2021) Challenges for biosimilars: focus on rheumatoid arthritis. Critical Reviews in Biotechnology 41:1, pages 121-153.
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Steffen Lippold, Alexander Knaupp, Arnoud H. de Ru, Rayman T. N. Tjokrodirijo, Peter A. van Veelen, Erwin van Puijenbroek, Steven W. de Taeye, Dietmar Reusch, Gestur Vidarsson, Manfred Wuhrer, Tilman Schlothauer & David Falck. (2021) Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometry. mAbs 13:1.
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Allyson Kwiatkowski, Carl Co, Sei Kameoka, An Zhang, John Coughlin, Tom Cameron, Eric Chiao, Svetlana Bergelson & Cullen Schmid Mason. (2020) Assessment of the role of afucosylated glycoforms on the in vitro antibody-dependent phagocytosis activity of an antibody to Aβ aggregates. mAbs 12:1.
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David J. Harvey. (2023) Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020. Mass Spectrometry Reviews 42:5, pages 1984-2206.
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Falk Nimmerjahn, Gestur Vidarsson & Mark S. Cragg. (2023) Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy. Nature Immunology 24:8, pages 1244-1255.
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Zhuoyu Liu, Yanjing Cao, Lei Zhang, Ya Xu & Zhongli Zhang. (2023) In-Depth Characterization of mAb Charge Variants by On-Line Multidimensional Liquid Chromatography-Mass Spectrometry. Analytical Chemistry 95:20, pages 7977-7984.
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Julie M. Fox, Vicky Roy, Bronwyn M. Gunn, Glen R. Bolton, Daved H. Fremont, Galit Alter, Michael S. Diamond & Austin W. Boesch. (2023) Enhancing the therapeutic activity of hyperimmune IgG against chikungunya virus using FcγRIIIa affinity chromatography. Frontiers in Immunology 14.
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Clarisse Gosset-Erard, Frédéric Aubriet, Emmanuelle Leize-Wagner, Yannis-Nicolas François & Patrick Chaimbault. (2023) Hyphenation of Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) with separation methods: The art of compromises and the possible - A review. Talanta 257, pages 124324.
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Victoria C. Cotham, Anita P. Liu, Shunhai Wang & Ning Li. (2023) A generic platform to couple affinity chromatography with native mass spectrometry for the analysis of therapeutic monoclonal antibodies. Journal of Pharmaceutical and Biomedical Analysis 228, pages 115337.
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Steffen Lippold, Michaela Hook, Christian Spick, Alexander Knaupp, Kevin Whang, Fabian Ruperti, Lance Cadang, Nisana Andersen, Annette Vogt, Michael Grote, Dietmar Reusch, Markus Haberger, Feng Yang & Tilman Schlothauer. (2023) CD3 Target Affinity Chromatography Mass Spectrometry as a New Tool for Function–Structure Characterization of T-Cell Engaging Bispecific Antibody Proteoforms and Product-Related Variants. Analytical Chemistry 95:4, pages 2260-2268.
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Mikhail Volkov, Maximilian Brinkhaus, Karin A. van Schie, Albert Bondt, Theresa Kissel, Elvera J. van der Kooi, Arthur E. H. Bentlage, Carolien A. M. Koeleman, Steven W. de Taeye, Ninotska I. Derksen, Radboud J. E. M. Dolhain, Ute Braig-Scherer, Tom W. J. Huizinga, Manfred Wuhrer, René E. M. Toes, Gestur Vidarsson & Diane van der Woude. (2023) IgG Fab Glycans Hinder FcRn-Mediated Placental Transport. The Journal of Immunology 210:2, pages 158-167.
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Thijs L.J. van Osch, Tamas Pongracz, Dionne M. Geerdes, Juk Yee Mok, Wim J.E. van Esch, Jan Voorberg, Rick Kapur, Leendert Porcelijn, Jean‐Louis H. Kerkhoffs, Pieter F. van der Meer, C. Ellen van der Schoot, Masja de Haas, Manfred Wuhrer & Gestur Vidarsson. (2022) Altered Fc glycosylation of anti‐HLA alloantibodies in hemato‐oncological patients receiving platelet transfusions. Journal of Thrombosis and Haemostasis 20:12, pages 3011-3025.
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Ettore Gilardoni & Luca Regazzoni. (2022) Liquid phase separation techniques for the characterization of monoclonal antibodies and bioconjugates. Journal of Chromatography Open 2, pages 100034.
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Guinevere S. M. Lageveen‐Kammeijer, Bernhard Kuster, Dietmar Reusch & Manfred Wuhrer. (2021) High sensitivity glycomics in biomedicine. Mass Spectrometry Reviews 41:6, pages 1014-1039.
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Sterre L. Siekman, Tamas Pongracz, Wenjun Wang, Jan Nouta, Peter G. Kremsner, Pedro Vieira da Silva-Neto, Meral Esen, Andrea Kreidenweiss, Jana Held, Átila Alexandre Trapé, Rolf Fendel, Isabel Kinney Ferreira de Miranda Santos & Manfred Wuhrer. (2022) The IgG glycome of SARS-CoV-2 infected individuals reflects disease course and severity. Frontiers in Immunology 13.
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Christoph Gstöttner, Alexander Knaupp, Gestur Vidarsson, Dietmar Reusch, Tilman Schlothauer, Manfred Wuhrer & Elena Domínguez-Vega. (2022) Affinity capillary electrophoresis – mass spectrometry permits direct binding assessment of IgG and FcγRIIa in a glycoform-resolved manner. Frontiers in Immunology 13.
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Manuel M. Vicente, Inês Alves, Joana Gaifem, Cláudia S. Rodrigues, Ângela Fernandes, Ana M. Dias, Jerko Štambuk, Tea Petrović, Pedro Oliveira, Frederico Ferreira‐da‐Silva, Adriana Soares, Nair Seixas, Tiago Teixeira, Luis Malheiro, Miguel M. Abreu, Gordan Lauc, Rui Sarmento e Castro & Salomé S. Pinho. (2022) Altered IgG glycosylation at COVID‐19 diagnosis predicts disease severity. European Journal of Immunology 52:6, pages 946-957.
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Elizabeth Edwards, Maria Livanos, Anja Krueger, Anne Dell, Stuart M. Haslam, C. Mark Smales & Daniel G. Bracewell. (2022) Strategies to control therapeutic antibody glycosylation during bioprocessing: Synthesis and separation. Biotechnology and Bioengineering 119:6, pages 1343-1358.
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Anuj Shrivastava, Srishti Joshi, Andras Guttman & Anurag S. Rathore. (2022) N-Glycosylation of monoclonal antibody therapeutics: A comprehensive review on significance and characterization. Analytica Chimica Acta 1209, pages 339828.
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Clizia Chinello, Noortje de Haan, Giulia Capitoli, Barbara Trezzi, Antonella Radice, Lisa Pagani, Lucrezia Criscuolo, Stefano Signorini, Stefania Galimberti, Renato Alberto Sinico, Manfred Wuhrer & Fulvio Magni. (2022) Definition of IgG Subclass-Specific Glycopatterns in Idiopathic Membranous Nephropathy: Aberrant IgG Glycoforms in Blood. International Journal of Molecular Sciences 23:9, pages 4664.
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Guusje van Schaick, Rob Haselberg, Govert W. Somsen, Manfred Wuhrer & Elena Domínguez-Vega. (2022) Studying protein structure and function by native separation–mass spectrometry. Nature Reviews Chemistry 6:3, pages 215-231.
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Yutaka MatsudaBrian A. Mendelsohn. (2021) Recent Advances in Drug–Antibody Ratio Determination of Antibody–Drug Conjugates. Chemical and Pharmaceutical Bulletin 69:10, pages 976-983.
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Thijs L. J. van Osch, Jan Nouta, Ninotska I. L. Derksen, Gerard van Mierlo, C. Ellen van der Schoot, Manfred Wuhrer, Theo Rispens & Gestur Vidarsson. (2021) Fc Galactosylation Promotes Hexamerization of Human IgG1, Leading to Enhanced Classical Complement Activation. The Journal of Immunology 207:6, pages 1545-1554.
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Yutaka Matsuda, Atis Chakrabarti, Kazutoshi Takahashi, Kei Yamada, Kunio Nakata, Tatsuya Okuzumi & Brian A. Mendelsohn. (2021) Chromatographic analysis of site-specific antibody-drug conjugates produced by AJICAP first-generation technology using a recombinant FcγIIIa receptor-ligand affinity column. Journal of Chromatography B 1177, pages 122753.
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Julien Camperi, Alexandre Goyon, Davy Guillarme, Kelly Zhang & Cinzia Stella. (2021) Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches. The Analyst 146:3, pages 747-769.
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Christoph Gstöttner, Harleen Kaur & Manfred Wuhrer. 2021. Monoclonal Antibodies. Monoclonal Antibodies
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Osmond D. Rebello, Richard A. Gardner, Paulina A. Urbanowicz, David N. Bolam, Lucy I. Crouch, David Falck & Daniel I. R. Spencer. (2020) A novel glycosidase plate-based assay for the quantification of galactosylation and sialylation on human IgG. Glycoconjugate Journal 37:6, pages 691-702.
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A. Robin Temming, Arthur E.H. Bentlage, Steven W. de Taeye, Gerlof P. Bosman, Suzanne N. Lissenberg-Thunnissen, Ninotska I.L. Derksen, Giso Brasser, Juk Yee Mok, Wim J.E. van Esch, Heather L. Howie, James C. Zimring & Gestur Vidarsson. (2020) Cross-reactivity of mouse IgG subclasses to human Fc gamma receptors: Antibody deglycosylation only eliminates IgG2b binding. Molecular Immunology 127, pages 79-86.
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Wolfgang Esser‐Skala, Therese Wohlschlager, Christof Regl & Christian G. Huber. (2020) A Simple Strategy to Eliminate Hexosylation Bias in the Relative Quantification of N‐Glycosylation in Biopharmaceuticals. Angewandte Chemie International Edition 59:37, pages 16225-16232.
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Wolfgang Esser‐Skala, Therese Wohlschlager, Christof Regl & Christian G. Huber. (2020) Eine einfache Strategie zur Korrektur des Fehlers aufgrund von Hexosylierung bei relativer Quantifizierung der N‐Glykosylierungsvarianten von Biopharmazeutika. Angewandte Chemie 132:37, pages 16359-16367.
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Steven W. de Taeye, Arthur E. H. Bentlage, Mirjam M. Mebius, Joyce I. Meesters, Suzanne Lissenberg-Thunnissen, David Falck, Thomas Sénard, Nima Salehi, Manfred Wuhrer, Janine Schuurman, Aran F. Labrijn, Theo Rispens & Gestur Vidarsson. (2020) FcγR Binding and ADCC Activity of Human IgG Allotypes. Frontiers in Immunology 11.
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Elisabeth A Erp, Anke J Lakerveld, Erik Graaf, Mads D Larsen, Rutger M Schepp, Agnes L Hipgrave Ederveen, Inge ML Ahout, Cornelis AM Haan, Manfred Wuhrer, Willem Luytjes, Gerben Ferwerda, Gestur Vidarsson & Puck B Kasteren. (2020) Natural killer cell activation by respiratory syncytial virus‐specific antibodies is decreased in infants with severe respiratory infections and correlates with Fc‐glycosylation. Clinical & Translational Immunology 9:2.
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Steffen Lippold, Simone Nicolardi, Manfred Wuhrer & David Falck. (2019) Proteoform-Resolved FcɤRIIIa Binding Assay for Fab Glycosylated Monoclonal Antibodies Achieved by Affinity Chromatography Mass Spectrometry of Fc Moieties. Frontiers in Chemistry 7.
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