2,463
Views
52
CrossRef citations to date
0
Altmetric
Original Research

Intranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients

, , , , , , , , , , , , , , , , , , , & show all
Article: e1019197 | Received 14 Jan 2015, Accepted 09 Feb 2015, Published online: 25 Jun 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Mohamad Irfan Mohamad Razif, Nabilah Nizar, Nur Hannah Zainal Abidin, Syasya Nasuha Muhammad Ali, Wan Nurul Najihah Wan Zarimi, Junaidi Khotib, Deny Susanti, Muhammad Taufiq Mohd Jailani & Muhammad Taher. (2023) Emergence of mRNA vaccines in the management of cancer. Expert Review of Vaccines 22:1, pages 629-642.
Read now
Martine Bloemendal, Kalijn F. Bol, Steve Boudewijns, Mark A.J. Gorris, Johannes H.W. de Wilt, Sandra A.J. Croockewit, Michelle M. van Rossum, Anna L. de Goede, Katja Petry, Rutger H.T. Koornstra, Carl Figdor, Winald R. Gerritsen, Gerty Schreibelt & I. Jolanda M. de Vries. (2022) Immunological responses to adjuvant vaccination with combined CD1c+ myeloid and plasmacytoid dendritic cells in stage III melanoma patients. OncoImmunology 11:1.
Read now
Elnaz Faghfuri, Farhad Pourfarzi, Amir Hossein Faghfouri, Mahdi Abdoli Shadbad, Khalil Hajiasgharzadeh & Behzad Baradaran. (2021) Recent developments of RNA-based vaccines in cancer immunotherapy. Expert Opinion on Biological Therapy 21:2, pages 201-218.
Read now
Wouter W. van Willigen, Martine Bloemendal, Marye J. Boers-Sonderen, Jan Willem B. de Groot, Rutger H.T. Koornstra, Astrid A.M. van der Veldt, John B. A. G. Haanen, Steve Boudewijns, Gerty Schreibelt, Winald R. Gerritsen, I. Jolanda M. de Vries & Kalijn F. Bol. (2020) Response and survival of metastatic melanoma patients treated with immune checkpoint inhibition for recurrent disease on adjuvant dendritic cell vaccination. OncoImmunology 9:1.
Read now
Abhishek D. Garg, Monica Vara Perez, Marco Schaaf, Patrizia Agostinis, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi. (2017) Trial watch: Dendritic cell-based anticancer immunotherapy. OncoImmunology 6:7.
Read now
Philipp Reautschnig, Paul Vogel & Thorsten Stafforst. (2017) The notorious R.N.A. in the spotlight - drug or target for the treatment of disease. RNA Biology 14:5, pages 651-668.
Read now
Jon Amund Kyte, Steinar Aamdal, Svein Dueland, Stein Sæbøe-Larsen, Else Marit Inderberg, Ulf Erik Madsbu, Eva Skovlund, Gustav Gaudernack & Gunnar Kvalheim. (2016) Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells. OncoImmunology 5:11.
Read now
Erika Vacchelli, Norma Bloy, Fernando Aranda, Aitziber Buqué, Isabelle Cremer, Sandra Demaria, Alexander Eggermont, Silvia Chiara Formenti, Wolf Hervé Fridman, Jitka Fucikova, Jérôme Galon, Radek Spisek, Eric Tartour, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi. (2016) Trial Watch: Immunotherapy plus radiation therapy for oncological indications. OncoImmunology 5:9.
Read now
Troels Holz Borch, Lotte Engell-Noerregaard, Trine Zeeberg Iversen, Eva Ellebaek, Özcan Met, Morten Hansen, Mads Hald Andersen, Per thor Straten & Inge Marie Svane. (2016) mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma. OncoImmunology 5:9.
Read now
Steve Boudewijns, Rutger H. T. Koornstra, Harm Westdorp, Gerty Schreibelt, Alfons J. M. van den Eertwegh, Marnix H. Geukes Foppen, John B. Haanen, I. Jolanda M. de Vries, Carl G. Figdor, Kalijn F. Bol & Winald R. Gerritsen. (2016) Ipilimumab administered to metastatic melanoma patients who progressed after dendritic cell vaccination. OncoImmunology 5:8.
Read now
Steve Boudewijns, Kalijn F. Bol, Gerty Schreibelt, Harm Westdorp, Johannes C. Textor, Michelle M. van Rossum, Nicole M. Scharenborg, Annemiek J. de Boer, Mandy W. M. M. van de Rakt, Jeanne M. Pots, Tom G. M. van Oorschot, Tjitske Duiveman-de Boer, Michel A. Olde Nordkamp, Wilmy S. E. C. van Meeteren, Winette T. A. van der Graaf, Johannes J. Bonenkamp, Johannes H. W. de Wilt, Erik H. J. G. Aarntzen, Cornelis J. A. Punt, Winald R. Gerritsen, Carl G. Figdor & I. Jolanda M. de Vries. (2016) Adjuvant dendritic cell vaccination induces tumor-specific immune responses in the majority of stage III melanoma patients. OncoImmunology 5:7.
Read now

Articles from other publishers (41)

Bevin Neill, Adriana Retamales Romero & Owen S. Fenton. (2023) Advances in Nonviral mRNA Delivery Materials and Their Application as Vaccines for Melanoma Therapy. ACS Applied Bio Materials.
Crossref
Bolin Wang, Jinli Pei, Shengnan Xu, Jie Liu & Jinming Yu. (2023) Recent advances in mRNA cancer vaccines: meeting challenges and embracing opportunities. Frontiers in Immunology 14.
Crossref
Hong Zhou, Yipeng Ma, Fenglan Liu, Bin Li, Dongjuan Qiao, Peigen Ren & Mingjun Wang. (2023) Current advances in cancer vaccines targeting NY-ESO-1 for solid cancer treatment. Frontiers in Immunology 14.
Crossref
Tian‐yi Zhang, Hang Xu, Xiao‐nan Zheng, Xing‐yu Xiong, Shi‐yu Zhang, Xian‐yanling Yi, Jin Li, Qiang Wei & Jian‐zhong Ai. (2023) Clinical benefit and safety associated with mRNA vaccines for advanced solid tumors: A meta‐analysis. MedComm 4:4.
Crossref
Jeffy G. Mattathil, Asisa Volz, Olusegun O. Onabajo, Sean Maynard, Sandra L. Bixler, Xiaoying X. Shen, Diego Vargas-Inchaustegui, Marjorie Robert-Guroff, Celia Lebranche, Georgia Tomaras, David Montefiori, Gerd Sutter & Joseph J. Mattapallil. (2023) Direct intranodal tonsil vaccination with modified vaccinia Ankara vaccine protects macaques from highly pathogenic SIVmac251. Nature Communications 14:1.
Crossref
Ya-Jia Xie, Wen-Qian Liu, Dan Li, Jin-Cai Hou, Paolo Saul Coghi & Xing-Xing Fan. (2023) Overcoming Suppressive Tumor Microenvironment by Vaccines in Solid Tumor. Vaccines 11:2, pages 394.
Crossref
Li-Chun Lu, Gen-Sheng Feng & Chih-Hung Hsu. (2023) Unfavorable tumor responses to immunotherapy in the liver: Lessons learned from clinical and preclinical studies. Journal of Cancer Research and Practice 10:2, pages 45.
Crossref
Tian-Yu Tang, Xing Huang, Gang Zhang, Ming-Hao Lu & Ting-Bo Liang. (2022) mRNA vaccine development for cholangiocarcinoma: a precise pipeline. Military Medical Research 9:1.
Crossref
Yangzhuo Gu, Jiangyao Duan, Na Yang, Yuxin Yang & Xing Zhao. (2022) mRNA vaccines in the prevention and treatment of diseases. MedComm 3:3.
Crossref
Shugang Qin, Xiaoshan Tang, Yuting Chen, Kepan Chen, Na Fan, Wen Xiao, Qian Zheng, Guohong Li, Yuqing Teng, Min Wu & Xiangrong Song. (2022) mRNA-based therapeutics: powerful and versatile tools to combat diseases. Signal Transduction and Targeted Therapy 7:1.
Crossref
Ankush Jajodia, Varun Goel, Nivedita Patnaik, Sunil Pasricha, Gurudutt Gupta, Ullas Batra & Vineet Talwar. (2022) Analysis of Spatial Heterogeneity of Responses in Metastatic Sites in Renal Cell Carcinoma Patients Treated with Nivolumab. Tomography 8:3, pages 1363-1373.
Crossref
Takashi Morisaki, Takafumi Morisaki, Makoto Kubo, Shinji Morisaki, Yusuke Nakamura & Hideya Onishi. (2022) Lymph Nodes as Anti-Tumor Immunotherapeutic Tools: Intranodal-Tumor-Specific Antigen-Pulsed Dendritic Cell Vaccine Immunotherapy. Cancers 14:10, pages 2438.
Crossref
Hajer Fritah, Raphaël Rovelli, Cheryl Lai-Lai Chiang & Lana E. Kandalaft. (2022) The current clinical landscape of personalized cancer vaccines. Cancer Treatment Reviews 106, pages 102383.
Crossref
Yingyue Ding, Zhaoting Li, Ana Jaklenec & Quanyin Hu. (2021) Vaccine delivery systems toward lymph nodes. Advanced Drug Delivery Reviews 179, pages 113914.
Crossref
Bruna Aparecida Souza Machado, Katharine Valéria Saraiva Hodel, Larissa Moraes dos Santos Fonseca, Luís Alberto Brêda Mascarenhas, Leone Peter Correia da Silva Andrade, Vinícius Pinto Costa Rocha, Milena Botelho Pereira Soares, Peter Berglund, Malcolm S. Duthie, Steven G. Reed & Roberto Badaró. (2021) The Importance of RNA-Based Vaccines in the Fight against COVID-19: An Overview. Vaccines 9:11, pages 1345.
Crossref
Furong Qin, Fan Xia, Hongli Chen, Bomiao Cui, Yun Feng, Ping Zhang, Jiao Chen & Min Luo. (2021) A Guide to Nucleic Acid Vaccines in the Prevention and Treatment of Infectious Diseases and Cancers: From Basic Principles to Current Applications. Frontiers in Cell and Developmental Biology 9.
Crossref
Pobitra Borah, Pran Kishore Deb, Nizar A. Al-Shar’i, Lina A. Dahabiyeh, Katharigatta N. Venugopala, Vinayak Singh, Pottathil Shinu, Snawar Hussain, Satyendra Deka, Balakumar Chandrasekaran & Da’san M. M. Jaradat. (2021) Perspectives on RNA Vaccine Candidates for COVID-19. Frontiers in Molecular Biosciences 8.
Crossref
Ignasi Esteban, Carmen Pastor-Quiñones, Lorena Usero, Montserrat Plana, Felipe García & Lorna Leal. (2021) In the Era of mRNA Vaccines, Is There Any Hope for HIV Functional Cure?. Viruses 13:3, pages 501.
Crossref
Annkristin Heine, Stefan Juranek & Peter Brossart. (2021) Clinical and immunological effects of mRNA vaccines in malignant diseases. Molecular Cancer 20:1.
Crossref
Dieter Stevens, Joline Ingels, Sandra Van Lint, Bart Vandekerckhove & Karim Vermaelen. (2021) Dendritic Cell-Based Immunotherapy in Lung Cancer. Frontiers in Immunology 11.
Crossref
Arthur Esprit, Wout de Mey, Rajendra Bahadur Shahi, Kris Thielemans, Lorenzo Franceschini & Karine Breckpot. (2020) Neo-Antigen mRNA Vaccines. Vaccines 8:4, pages 776.
Crossref
Rita Ahmed, Naya Sayegh, Michele Graciotti & Lana E. Kandalaft. (2020) Electroporation as a method of choice to generate genetically modified dendritic cell cancer vaccines. Current Opinion in Biotechnology 65, pages 142-155.
Crossref
Masahiro Okada, Kanako Shimizu, Tomonori Iyoda, Shogo Ueda, Jun Shinga, Yoshiki Mochizuki, Takashi Watanabe, Osamu Ohara & Shin-ichiro Fujii. (2020) PD-L1 Expression Affects Neoantigen Presentation. iScience 23:6, pages 101238.
Crossref
Muhammad Imran Qadir, Sherien Bukhat, Sumaira Rasul, Hamid Manzoor & Majid Manzoor. (2019) RNA therapeutics: Identification of novel targets leading to drug discovery. Journal of Cellular Biochemistry 121:2, pages 898-929.
Crossref
Jan Dörrie, Niels Schaft, Gerold Schuler & Beatrice Schuler-Thurner. (2020) Therapeutic Cancer Vaccination with Ex Vivo RNA-Transfected Dendritic Cells—An Update. Pharmaceutics 12:2, pages 92.
Crossref
Adam J. Grippin, Brandon Wummer, Tyler Wildes, Kyle Dyson, Vrunda Trivedi, Changlin Yang, Mathew Sebastian, Hector R. Mendez-Gomez, Suraj Padala, Mackenzie Grubb, Matthew Fillingim, Adam Monsalve, Elias J. Sayour, Jon Dobson & Duane A. Mitchell. (2019) Dendritic Cell-Activating Magnetic Nanoparticles Enable Early Prediction of Antitumor Response with Magnetic Resonance Imaging. ACS Nano 13:12, pages 13884-13898.
Crossref
Harm Westdorp, Jeroen H. A. Creemers, Inge M. van Oort, Gerty Schreibelt, Mark A. J. Gorris, Niven Mehra, Michiel Simons, Anna L. de Goede, Michelle M. van Rossum, Alexandra J. Croockewit, Carl G. Figdor, J. Alfred Witjes, Erik H. J. G. Aarntzen, Roel D. M. Mus, Mareke Brüning, Katja Petry, Martin Gotthardt, Jelle O. Barentsz, I. Jolanda M. de Vries & Winald R. Gerritsen. (2019) Blood-derived dendritic cell vaccinations induce immune responses that correlate with clinical outcome in patients with chemo-naive castration-resistant prostate cancer. Journal for ImmunoTherapy of Cancer 7:1.
Crossref
Carsten Weishaupt, Meike Steinert, Georg Brunner, Hans‐Joachim Schulze, Robert C. Fuhlbrigge, Tobias Goerge & Karin Loser. (2019) Activation of human vascular endothelium in melanoma metastases induces ICAM ‐1 and E‐selectin expression and results in increased infiltration with effector lymphocytes . Experimental Dermatology 28:11, pages 1258-1269.
Crossref
Li-Chun Lu, Chiun Hsu, Yu-Yun Shao, Yee Chao, Chia-Jui Yen, I-Lun Shih, Yi-Ping Hung, Chun-Jung Chang, Ying-Chun Shen, Jhe-Cyuan Guo, Tsung-Hao Liu, Chih-Hung Hsu & Ann-Lii Cheng. (2019) Differential Organ-Specific Tumor Response to Immune Checkpoint Inhibitors in Hepatocellular Carcinoma. Liver Cancer 8:6, pages 480-490.
Crossref
CHARLOTTE DE Wolf, MARJA VAN DE BOVENKAMP & MARCEL HOEFNAGEL. (2018) Regulatory perspective on in vitro potency assays for human dendritic cells used in anti-tumor immunotherapy. Cytotherapy 20:11, pages 1289-1308.
Crossref
Chunsong Yu & Haipeng Liu. 2018. Immunoregulatory Aspects of Immunotherapy. Immunoregulatory Aspects of Immunotherapy.
Sija Landman, Vivian L. de Oliveira, Piet E. J. van Erp, Esther Fasse, Stijn C. G. Bauland, Irma Joosten & Hans J. P. M. Koenen. (2018) Intradermal injection of low dose human regulatory T cells inhibits skin inflammation in a humanized mouse model. Scientific Reports 8:1.
Crossref
Norbert Pardi, Michael J. Hogan, Frederick W. Porter & Drew Weissman. (2018) mRNA vaccines — a new era in vaccinology. Nature Reviews Drug Discovery 17:4, pages 261-279.
Crossref
Olivier Manches, Luciana R. Muniz & Nina Bhardwaj. 2018. Hematology. Hematology 247 260.e6 .
Vivek Murthy, Janna Minehart & Daniel H Sterman. (2017) Local Immunotherapy of Cancer: Innovative Approaches to Harnessing Tumor-Specific Immune Responses. JNCI: Journal of the National Cancer Institute 109:12.
Crossref
Vimal K. Udhayakumar, Ans De Beuckelaer, Joanne McCaffrey, Cian M. McCrudden, Jonathan L. Kirschman, Daryll Vanover, Lien Van Hoecke, Kenny Roose, Kim Deswarte, Bruno G. De Geest, Stefan Lienenklaus, Philip J. Santangelo, Johan Grooten, Helen O. McCarthy & Stefaan De Koker. (2017) Arginine‐Rich Peptide‐Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide. Advanced Healthcare Materials 6:13, pages 1601412.
Crossref
Kerstin F. Gerer, Stefanie Hoyer, Jan Dörrie & Niels Schaft. 2017. RNA Vaccines. RNA Vaccines 165 178 .
Jurjen Tel, Rutger Koornstra, Nienke de Haas, Vincent van Deutekom, Harm Westdorp, Steve Boudewijns, Nielka van Erp, Stefania Di Blasio, Winald Gerritsen, Carl G. Figdor, I. Jolanda M. de Vries & Stanleyson V. Hato. (2016) Preclinical exploration of combining plasmacytoid and myeloid dendritic cell vaccination with BRAF inhibition. Journal of Translational Medicine 14:1.
Crossref
Steve Boudewijns, Harm Westdorp, Rutger H.T. Koornstra, Erik H.J.G. Aarntzen, Gerty Schreibelt, Jeroen H.A. Creemers, Cornelis J.A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Winald R. Gerritsen & Kalijn F. Bol. (2016) Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients. Journal of Immunotherapy 39:6, pages 241-248.
Crossref
Angela Vasaturo, Altuna Halilovic, Kalijn F. Bol, Dagmar I. Verweij, Willeke A.M. Blokx, Cornelis J.A. Punt, Patricia J.T.A. Groenen, J. Han J.M. van Krieken, Johannes Textor, I. Jolanda M. de Vries & Carl G. Figdor. (2016) T-cell Landscape in a Primary Melanoma Predicts the Survival of Patients with Metastatic Disease after Their Treatment with Dendritic Cell Vaccines. Cancer Research 76:12, pages 3496-3506.
Crossref
Kalijn F. Bol, Erik H. J. G. Aarntzen, Jeanette M. Pots, Michel A. M. Olde Nordkamp, Mandy W. M. M. van de Rakt, Nicole M. Scharenborg, Annemiek J. de Boer, Tom G. M. van Oorschot, Sandra A. J. Croockewit, Willeke A. M. Blokx, Wim J. G. Oyen, Otto C. Boerman, Roel D. M. Mus, Michelle M. van Rossum, Chantal A. A. van der Graaf, Cornelis J. A. Punt, Gosse J. Adema, Carl G. Figdor, I. Jolanda M. de Vries & Gerty Schreibelt. (2016) Prophylactic vaccines are potent activators of monocyte-derived dendritic cells and drive effective anti-tumor responses in melanoma patients at the cost of toxicity. Cancer Immunology, Immunotherapy 65:3, pages 327-339.
Crossref