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Transcriptional Regulation

Phenobarbital-Responsive Nuclear Translocation of the Receptor CAR in Induction of the CYP2B Gene

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Pages 6318-6322 | Received 16 Apr 1999, Accepted 16 Jun 1999, Published online: 27 Mar 2023

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Thomas K. H. Chang & David J. Waxman. (2006) Synthetic Drugs and Natural Products as Modulators of Constitutive Androstane Receptor (Car) and Pregnane X Receptor (PXR). Drug Metabolism Reviews 38:1-2, pages 51-73.
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Wei-Hung Chan, Wei-Zen Sun & Tzuu-Huei Ueng. (2005) Induction of Rat Hepatic Cytochrome P-450 by Ketamine and its Toxicological Implications. Journal of Toxicology and Environmental Health, Part A 68:17-18, pages 1581-1597.
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Susumu Kodama, Chika Koike, Masahiko Negishi & Yukio Yamamoto. (2004) Nuclear Receptors CAR and PXR Cross Talk with FOXO1 To Regulate Genes That Encode Drug-Metabolizing and Gluconeogenic Enzymes. Molecular and Cellular Biology 24:18, pages 7931-7940.
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Igor Zelko, Tatsuya Sueyoshi, Takeshi Kawamoto, Rick Moore & Masahiko Negishi. (2001) The Peptide Near the C Terminus Regulates Receptor CAR Nuclear Translocation Induced by Xenochemicals in Mouse Liver. Molecular and Cellular Biology 21:8, pages 2838-2846.
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Iphigenia Tzameli, Pavlos Pissios, Erin G. Schuetz & David D. Moore. (2000) The Xenobiotic Compound 1,4-Bis[2-(3,5-Dichloropyridyloxy)]Benzene Is an Agonist Ligand for the Nuclear Receptor CAR. Molecular and Cellular Biology 20:9, pages 2951-2958.
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