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DNA Dynamics and Chromosome Structure

Long-Distance Control of Origin Choice and Replication Timing in the Human β-Globin Locus Are Independent of the Locus Control Region

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Pages 5581-5591 | Received 03 Jan 2000, Accepted 24 Apr 2000, Published online: 28 Mar 2023

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Articles from other publishers (72)

Lina-Marie Briu, Chrystelle Maric & Jean-Charles Cadoret. (2021) Replication Stress, Genomic Instability, and Replication Timing: A Complex Relationship. International Journal of Molecular Sciences 22:9, pages 4764.
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Joel B. Miesfeld, Noor M. Ghiasvand, Brennan Marsh-Armstrong, Nicholas Marsh-Armstrong, Eric B. Miller, Pengfei Zhang, Suman K. Manna, Robert J. Zawadzki, Nadean L. Brown & Tom Glaser. (2020) The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development . Proceedings of the National Academy of Sciences 117:35, pages 21690-21700.
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Stefano Gnan, Yaqun Liu, Manuela Spagnuolo & Chun-Long Chen. (2020) The impact of transcription-mediated replication stress on genome instability and human disease. Genome Instability & Disease 1:5, pages 207-234.
Crossref
Claire Marchal, Jiao Sima & David M. Gilbert. (2019) Control of DNA replication timing in the 3D genome. Nature Reviews Molecular Cell Biology 20:12, pages 721-737.
Crossref
Jiao Sima, Abhijit Chakraborty, Vishnu Dileep, Marco Michalski, Kyle N. Klein, Nicolas P. Holcomb, Jesse L. Turner, Michelle T. Paulsen, Juan Carlos Rivera-Mulia, Claudia Trevilla-Garcia, Daniel A. Bartlett, Peiyao A. Zhao, Brian K. Washburn, Elphège P. Nora, Katerina Kraft, Stefan Mundlos, Benoit G. Bruneau, Mats Ljungman, Peter Fraser, Ferhat Ay & David M. Gilbert. (2019) Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication. Cell 176:4, pages 816-830.e18.
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Amir Hosseini & Saverio Minucci. 2018. Epigenetics in Human Disease. Epigenetics in Human Disease 141 217 .
Sung-Hun Lee & Young Zoon Kim. 2017. DNA and Histone Methylation as Cancer Targets. DNA and Histone Methylation as Cancer Targets 347 376 .
Young Zoon Kim. (2014) Altered Histone Modifications in Gliomas. Brain Tumor Research and Treatment 2:1, pages 7.
Crossref
Chenyi Liu & Lincoln Stein. 2014. Systems Analysis of Chromatin-Related Protein Complexes in Cancer. Systems Analysis of Chromatin-Related Protein Complexes in Cancer 65 85 .
Andrew Fritz, Seema Sinha, Narasimharao Marella & Ronald Berezney. (2013) Alterations in replication timing of cancer-related genes in malignant human breast cancer cells. Journal of Cellular Biochemistry 114:5, pages 1074-1083.
Crossref
Nathan Donley & Mathew J. Thayer. (2013) DNA replication timing, genome stability and cancer. Seminars in Cancer Biology 23:2, pages 80-89.
Crossref
T. D. Kolesnikova. (2013) Regulation of DNA replication timing. Molecular Biology 47:1, pages 12-33.
Crossref
S. V. Razin, S. V. Ulianov, E. S. Ioudinkova, E. S. Gushchanskaya, A. A. Gavrilov & O. V. Iarovaia. (2013) Domains of α- and β-globin genes in the context of the structural-functional organization of the eukaryotic genome. Biochemistry (Moscow) 77:13, pages 1409-1423.
Crossref
Benjamin D. Pope, Tamir Chandra, Quinton Buckley, Matthew Hoare, Tyrone Ryba, Frances K. Wiseman, Anna Kuta, Michael D. Wilson, Duncan T. Odom & David M. Gilbert. (2012) Replication-timing boundaries facilitate cell-type and species-specific regulation of a rearranged human chromosome in mouse. Human Molecular Genetics 21:19, pages 4162-4170.
Crossref
Satoru Watanabe, Ryudo Ohbayashi, Yuh Shiwa, Aska Noda, Yu Kanesaki, Taku Chibazakura & Hirofumi Yoshikawa. (2012) Light-dependent and asynchronous replication of cyanobacterial multi-copy chromosomes. Molecular Microbiology 83:4, pages 856-865.
Crossref
Ciro Mercurio, Simon Plyte & Saverio Minucci. 2012. Epigenetics in Human Disease. Epigenetics in Human Disease 53 87 .
Joana Santos, C Filipe Pereira, Aida Di-Gregorio, Thomas Spruce, Olivia Alder, Tristan Rodriguez, Véronique Azuara, Matthias Merkenschlager & Amanda G Fisher. (2010) Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo. Epigenetics & Chromatin 3:1.
Crossref
Joshua C. Black, Andrew Allen, Capucine Van Rechem, Emily Forbes, Michelle Longworth, Katrin Tschöp, Claire Rinehart, Jonathan Quiton, Ryan Walsh, Andrea Smallwood, Nicholas J. Dyson & Johnathan R. Whetstine. (2010) Conserved Antagonism between JMJD2A/KDM4A and HP1γ during Cell Cycle Progression. Molecular Cell 40:5, pages 736-748.
Crossref
Stepan N. Belyakin, Vladimir N. Babenko, Daniil A. Maksimov, Viktor V. Shloma, Evgeny Z. Kvon, Elena S. Belyaeva & Igor F. Zhimulev. (2010) Gene density profile reveals the marking of late replicated domains in the Drosophila melanogaster genome. Chromosoma 119:6, pages 589-600.
Crossref
Subhradip Karmakar, Milind C Mahajan, Vincent Schulz, Gokul Boyapaty & Sherman M Weissman. (2010) A multiprotein complex necessary for both transcription and DNA replication at the β-globin locus. The EMBO Journal 29:19, pages 3260-3271.
Crossref
Hisao Masai, Seiji Matsumoto, Zhiying You, Naoko Yoshizawa-Sugata & Masako Oda. (2010) Eukaryotic Chromosome DNA Replication: Where, When, and How?. Annual Review of Biochemistry 79:1, pages 89-130.
Crossref
A. de Morgan, L. Brodsky, Y. Ronin, E. Nevo, A. Korol & Y. Kashi. (2010) Genome-wide analysis of DNA turnover and gene expression in stationary-phase Saccharomyces cerevisiae. Microbiology 156:6, pages 1758-1771.
Crossref
Carla Sawan & Zdenko Herceg. 2010. Epigenetics and Cancer, Part A. Epigenetics and Cancer, Part A 57 85 .
Benjamin D. Pope, Ichiro Hiratani & David M. Gilbert. (2009) Domain-wide regulation of DNA replication timing during mammalian development. Chromosome Research 18:1, pages 127-136.
Crossref
Michaela Schwaiger, Michael B. Stadler, Oliver Bell, Hubertus Kohler, Edward J. Oakeley & Dirk Schübeler. (2009) Chromatin state marks cell-type- and gender-specific replication of the Drosophila genome . Genes & Development 23:5, pages 589-601.
Crossref
Florian Grasser, Michaela Neusser, Heike Fiegler, Tobias Thormeyer, Marion Cremer, Nigel P. Carter, Thomas Cremer & Stefan Müller. (2008) Replication-timing-correlated spatial chromatin arrangements in cancer and in primate interphase nuclei. Journal of Cell Science 121:11, pages 1876-1886.
Crossref
Pascal Bernard, Christine Katrin Schmidt, Sabine Vaur, Sonia Dheur, Julie Drogat, Sylvie Genier, Karl Ekwall, Frank Uhlmann & Jean-Paul Javerzat. (2007) Cell-cycle regulation of cohesin stability along fission yeast chromosomes. The EMBO Journal 27:1, pages 111-121.
Crossref
R Murr, T Vaissière, C Sawan, V Shukla & Z Herceg. (2007) Orchestration of chromatin-based processes: mind the TRRAP. Oncogene 26:37, pages 5358-5372.
Crossref
Mirit I. Aladjem. (2007) Replication in context: dynamic regulation of DNA replication patterns in metazoans. Nature Reviews Genetics 8:8, pages 588-600.
Crossref
Guillermo Barreto, Andrea Schäfer, Joachim Marhold, Dirk Stach, Suresh K. Swaminathan, Vikas Handa, Gabi Döderlein, Nicole Maltry, Wei Wu, Frank Lyko & Christof Niehrs. (2007) Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 445:7128, pages 671-675.
Crossref
Igor N. Chesnokov. 2007. 69 109 .
Véronique Azuara. (2006) Profiling of DNA replication timing in unsynchronized cell populations. Nature Protocols 1:4, pages 2171-2177.
Crossref
Daniele Zink. (2006) The temporal program of DNA replication: new insights into old questions. Chromosoma 115:4, pages 273-287.
Crossref
S. G. Gregory, K. F. Barlow, K. E. McLay, R. Kaul, D. Swarbreck, A. Dunham, C. E. Scott, K. L. Howe, K. Woodfine, C. C. A. Spencer, M. C. Jones, C. Gillson, S. Searle, Y. Zhou, F. Kokocinski, L. McDonald, R. Evans, K. Phillips, A. Atkinson, R. Cooper, C. Jones, R. E. Hall, T. D. Andrews, C. Lloyd, R. Ainscough, J. P. Almeida, K. D. Ambrose, F. Anderson, R. W. Andrew, R. I. S. Ashwell, K. Aubin, A. K. Babbage, C. L. Bagguley, J. Bailey, H. Beasley, G. Bethel, C. P. Bird, S. Bray-Allen, J. Y. Brown, A. J. Brown, D. Buckley, J. Burton, J. Bye, C. Carder, J. C. Chapman, S. Y. Clark, G. Clarke, C. Clee, V. Cobley, R. E. Collier, N. Corby, G. J. Coville, J. Davies, R. Deadman, M. Dunn, M. Earthrowl, A. G. Ellington, H. Errington, A. Frankish, J. Frankland, L. French, P. Garner, J. Garnett, L. Gay, M. R. J. Ghori, R. Gibson, L. M. Gilby, W. Gillett, R. J. Glithero, D. V. Grafham, C. Griffiths, S. Griffiths-Jones, R. Grocock, S. Hammond, E. S. I. Harrison, E. Hart, E. Haugen, P. D. Heath, S. Holmes, K. Holt, P. J. Howden, A. R. Hunt, S. E. Hunt, G. Hunter, J. Isherwood, R. James, C. Johnson, D. Johnson, A. Joy, M. Kay, J. K. Kershaw, M. Kibukawa, A. M. Kimberley, A. King, A. J. Knights, H. Lad, G. Laird, S. Lawlor, D. A. Leongamornlert, D. M. Lloyd, J. Loveland, J. Lovell, M. J. Lush, R. Lyne, S. Martin, M. Mashreghi-Mohammadi, L. Matthews, N. S. W. Matthews, S. McLaren, S. Milne, S. Mistry, M. J. F. M oore, T. Nickerson, C. N. O'Dell, K. Oliver, A. Palmeiri, S. A. Palmer, A. Parker, D. Patel, A. V. Pearce, A. I. Peck, S. Pelan, K. Phelps, B. J. Phillimore, R. Plumb, J. Rajan, C. Raymond, G. Rouse, C. Saenphimmachak, H. K. Sehra, E. Sheridan, R. Shownkeen, S. Sims, C. D. Skuce, M. Smith, C. Steward, S. Subramanian, N. Sycamore, A. Tracey, A. Tromans, Z. Van Helmond, M. Wall, J. M. Wallis, S. White, S. L. Whitehead, J. E. Wilkinson, D. L. Willey, H. Williams, L. Wilming, P. W. Wray, Z. Wu, A. Coulson, M. Vaudin, J. E. Sulston, R. Durbin, T. Hubbard, R. Wooster, I. Dunham, N. P. Carter, G. McVean, M. T. Ross, J. Harrow, M. V. Olson, S. Beck, J. Rogers & D. R. Bentley. (2006) The DNA sequence and biological annotation of human chromosome 1. Nature 441:7091, pages 315-321.
Crossref
Toshiro Hayashida, Masako Oda, Kanako Ohsawa, Atsumi Yamaguchi, Takumi Hosozawa, Richard M. Locksley, Mauro Giacca, Hisao Masai & Shoichiro Miyatake. (2006) Replication Initiation from a Novel Origin Identified in the Th2 Cytokine Cluster Locus Requires a Distant Conserved Noncoding Sequence. The Journal of Immunology 176:9, pages 5446-5454.
Crossref
Michaela Schwaiger & Dirk Schübeler. (2006) A question of timing: emerging links between transcription and replication. Current Opinion in Genetics & Development 16:2, pages 177-183.
Crossref
Hidetsugu Kohzaki & Yota Murakami. (2005) Transcription factors and DNA replication origin selection. BioEssays 27:11, pages 1107-1116.
Crossref
Silvia Diaz-Perez, Yan Ouyang, Vanessa Perez, Roxanna Cisneros, Moira Regelson & York Marahrens. (2005) The Element(s) at the Nontranscribed Xist Locus of the Active X Chromosome Controls Chromosomal Replication Timing in the Mouse . Genetics 171:2, pages 663-672.
Crossref
Lyubomira Chakalova, Emmanuel Debrand, Jennifer A. Mitchell, Cameron S. Osborne & Peter Fraser. (2005) Replication and transcription: Shaping the landscape of the genome. Nature Reviews Genetics 6:9, pages 669-677.
Crossref
Laura Lande-Diner & Howard Cedar. (2005) Silence of the genes — mechanisms of long-term repression. Nature Reviews Genetics 6:8, pages 648-654.
Crossref
Gabriela G. Loots, Michaela Kneissel, Hansjoerg Keller, Myma Baptist, Jessie Chang, Nicole M. Collette, Dmitriy Ovcharenko, Ingrid Plajzer-Frick & Edward M. Rubin. (2005) Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease. Genome Research 15:7, pages 928-935.
Crossref
S. V. Razin & O. V. Iarovaia. (2005) Spatial Organization of DNA in the Nucleus May Determine Positions of Recombination Hot Spots. Molecular Biology 39:4, pages 543-548.
Crossref
Edda Koina & Anita Piper. (2005) An inactive X specific replication origin associated with a matrix attachment region in the human X linkedHPRT gene. Journal of Cellular Biochemistry 95:2, pages 391-402.
Crossref
Eric J. WhiteOlof EmanuelssonDavid ScalzoThomas RoyceSteven KosakEdward J. OakeleySherman WeissmanMark GersteinMark GroudineMichael SnyderDirk Schübeler. (2004) DNA replication-timing analysis of human chromosome 22 at high resolution and different developmental states. Proceedings of the National Academy of Sciences 101:51, pages 17771-17776.
Crossref
Ichiro Hiratani, Amanda Leskovar & David M. Gilbert. (2004) Differentiation-induced replication-timing changes are restricted to AT-rich/long interspersed nuclear element (LINE)-rich isochores. Proceedings of the National Academy of Sciences 101:48, pages 16861-16866.
Crossref
María Gómez & Neil Brockdorff. (2004) Heterochromatin on the inactive X chromosome delays replication timing without affecting origin usage. Proceedings of the National Academy of Sciences 101:18, pages 6923-6928.
Crossref
Sanjay Vashee, Christin Cvetic, Wenyan Lu, Pamela Simancek, Thomas J. Kelly & Johannes C. Walter. (2003) Sequence-independent DNA binding and replication initiation by the human origin recognition complex. Genes & Development 17:15, pages 1894-1908.
Crossref
Yuki Katou, Yutaka Kanoh, Masashige Bando, Hideki Noguchi, Hirokazu Tanaka, Toshihiko Ashikari, Katsunori Sugimoto & Katsuhiko Shirahige. (2003) S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex. Nature 424:6952, pages 1078-1083.
Crossref
Véronique Azuara, Karen E. Brown, Ruth R. E. Williams, Natasha Webb, Niall Dillon, Richard Festenstein, Veronica Buckle, Matthias Merkenschlager & Amanda G. Fisher. (2003) Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication. Nature Cell Biology 5:7, pages 668-674.
Crossref
Chii Mei Lin, Haiqing Fu, Maria Martinovsky, Eric Bouhassira & Mirit I. Aladjem. (2003) Dynamic Alterations of Replication Timing in Mammalian Cells. Current Biology 13:12, pages 1019-1028.
Crossref
Siavash K. Kurdistani & Michael Grunstein. (2003) Histone acetylation and deacetylation in yeast. Nature Reviews Molecular Cell Biology 4:4, pages 276-284.
Crossref
Joost Gribnau, Konrad Hochedlinger, Ken Hata, En Li & Rudolf Jaenisch. (2003) Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization. Genes & Development 17:6, pages 759-773.
Crossref
Alon Goren & Howard Cedar. (2003) Replicating by the clock. Nature Reviews Molecular Cell Biology 4:1, pages 25-32.
Crossref
H.J Lipps, A.C.W Jenke, K Nehlsen, M.F Scinteie, I.M Stehle & J Bode. (2003) Chromosome-based vectors for gene therapy. Gene 304, pages 23-33.
Crossref
Xiangdong Fang, Kenneth R. Peterson, Qiliang Li & George Stamatoyannopoulos. 2003. Gene Transfer and Expression in Mammalian Cells. Gene Transfer and Expression in Mammalian Cells 397 409 .
Sergey V Razin, Catherine M Farrell & Félix Recillas-Targa. 2003. 63 125 .
Isabelle A. Lucas & M.K. Raghuraman. 2003. 1 73 .
Dirk Schübeler, David Scalzo, Charles Kooperberg, Bas van Steensel, Jeffrey Delrow & Mark Groudine. (2002) Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing. Nature Genetics 32:3, pages 438-442.
Crossref
Jianmin Zhang, Feng Xu, Tamar Hashimshony, Ilana Keshet & Howard Cedar. (2002) Establishment of transcriptional competence in early and late S phase. Nature 420:6912, pages 198-202.
Crossref
Maria Vogelauer, Liudmilla Rubbi, Isabelle Lucas, Bonita J Brewer & Michael Grunstein. (2002) Histone Acetylation Regulates the Time of Replication Origin Firing. Molecular Cell 10:5, pages 1223-1233.
Crossref
G Bronner, B Spataro, M Page, C Gautier & F Rechenmann. (2002) Modeling comparative mapping using objects and associations. Computers & Chemistry 26:5, pages 413-420.
Crossref
David M Gilbert. (2002) Replication timing and transcriptional control: beyond cause and effect. Current Opinion in Cell Biology 14:3, pages 377-383.
Crossref
Padraic P. Levings & Jörg Bungert. (2002) The human β-globin locus control region. European Journal of Biochemistry 269:6, pages 1589-1599.
Crossref
Susan M. Keezer & David M. Gilbert. (2002) Sensitivity of the Origin Decision Point to Specific Inhibitors of Cellular Signaling and Metabolism. Experimental Cell Research 273:1, pages 54-64.
Crossref
Vera Djeliova, George Russev & Boyka Anachkova. (2002) DNase I sensitive site in the core region of the human ?-globin origin of replication. Journal of Cellular Biochemistry 87:3, pages 279-283.
Crossref
Igor Chesnokov, Dirk Remus & Michael Botchan. (2001) Functional analysis of mutant and wild-type Drosophila origin recognition complex . Proceedings of the National Academy of Sciences 98:21, pages 11997-12002.
Crossref
David M. Gilbert. (2001) Making Sense of Eukaryotic DNA Replication Origins. Science 294:5540, pages 96-100.
Crossref
Mauro Anglana & Michelle Debatisse. (2001) Dual Control of Replication Timing. Journal of Biological Chemistry 276:39, pages 36639-36646.
Crossref
Marcel Méchali. (2001) DNA replication origins: from sequence specificity to epigenetics. Nature Reviews Genetics 2:8, pages 640-645.
Crossref
Feng Li, Jianhua Chen, Masako Izumi, Mark C. Butler, Susan M. Keezer & David M. Gilbert. (2001) The replication timing program of the Chinese hamster β-globin locus is established coincident with its repositioning near peripheral heterochromatin in early G1 phase. Journal of Cell Biology 154:2, pages 283-292.
Crossref
Daniel M. Cimbora & Mark Groudine. (2001) The Control of Mammalian DNA Replication. Cell 104:5, pages 643-646.
Crossref
Jiao Sima, Abhijit Chakraborty, Vishnu Dileep, Marco Michalski, Juan Carlos Rivera-Mulia, Claudia Trevilla-Garcia, Kyle N. Klein, Daniel Bartlett, Brian K. Washburn, Michelle T. Paulsen, Daniel Vera, Elphhge P. Nora, Katerina Kraft, Stefan Mundlos, Benoit G. Bruneau, Mats Ljungman, Peter Fraser, Ferhat Ay & David M. Gilbert. (2018) Identification of <i>cis</i> Elements for Spatio-temporal Control of DNA Replication. SSRN Electronic Journal.
Crossref

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