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Molecular and Cellular Biology Volume 20, 2000 - Issue 21
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Cell Growth and Development

Profilin II Is Alternatively Spliced, Resulting in Profilin Isoforms That Are Differentially Expressed and Have Distinct Biochemical Properties

Anja Lambrechts1 Department of Biochemistry, Ghent University and Flanders Interuniversity Institute for Biotechnology, 9000Ghent, Belgium
,
Attila Braun2 Department of Experimental Pathology, Lund University, 22 1 85Lund, Sweden
,
Veronique Jonckheere1 Department of Biochemistry, Ghent University and Flanders Interuniversity Institute for Biotechnology, 9000Ghent, Belgium
,
Attila Aszodi2 Department of Experimental Pathology, Lund University, 22 1 85Lund, Sweden
,
Lorene M. Lanier3 Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts02139-4307
,
Johan Robbens1 Department of Biochemistry, Ghent University and Flanders Interuniversity Institute for Biotechnology, 9000Ghent, Belgium
,
Inge Van Colen1 Department of Biochemistry, Ghent University and Flanders Interuniversity Institute for Biotechnology, 9000Ghent, Belgium
,
Joël Vandekerckhove1 Department of Biochemistry, Ghent University and Flanders Interuniversity Institute for Biotechnology, 9000Ghent, Belgium
,
Reinhard Fässler2 Department of Experimental Pathology, Lund University, 22 1 85Lund, Sweden
&
Christophe Ampe1 Department of Biochemistry, Ghent University and Flanders Interuniversity Institute for Biotechnology, 9000Ghent, BelgiumCorrespondence[email protected]
 show all
Pages 8209-8219 | Received 09 Mar 2000, Accepted 08 Aug 2000, Published online: 28 Mar 2023

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Zhijie Ding, Yong Ho Bae & Partha Roy. (2012) Molecular insights on context-specific role of profilin-1 in cell migration. Cell Adhesion & Migration 6:5, pages 442-534.
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Pratibha Verma, Smita Yevate, Jeeva S. E.Priyanka Parte. (2023) Upregulation of Profilin 2 on HDAC6 overexpression in mouse GC-1 cells and its putative role in germ cell migration in the testis. Cell and Tissue Research.
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Marina Di Domenico, Melanie Jokwitz, Walter Witke & Pietro Pilo Boyl. (2021) Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure. Cells 10:9, pages 2310.
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Kai Murk, Marta Ornaghi & Juliane Schiweck. (2021) Profilin Isoforms in Health and Disease – All the Same but Different. Frontiers in Cell and Developmental Biology 9.
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Rita Pinto‐Costa & Mónica M. Sousa. (2020) Profilin as a dual regulator of actin and microtubule dynamics. Cytoskeleton 77:3-4, pages 76-83.
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Lisa Marie Walter, Peter Franz, Robert Lindner, Georgios Tsiavaliaris, Niko Hensel & Peter Claus. (2019) Profilin2a‐phosphorylation as a regulatory mechanism for actin dynamics. The FASEB Journal 34:2, pages 2147-2160.
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Huaqin Li, Lianjie Hou, Yu Zhang, Fangyi Jiang, Yifan Zhu, Qing X. Li, Ching Yuan Hu & Chong Wang. (2019) PFN2a Suppresses C2C12 Myogenic Development by Inhibiting Proliferation and Promoting Apoptosis via the p53 Pathway. Cells 8:9, pages 959.
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Keisuke Ohta, Yusuke Matsumoto & Machiko Nishio. (2019) Profilin2 is required for filamentous actin formation induced by human parainfluenza virus type 2. Virology 533, pages 108-114.
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Ammarah Fateen, Syed Aoun Ali, Deeba Noreen Baig & Zarrin Basharat. (2018) Profilin (pfn) isoforms transcriptional and bioinformatic exploration and Mus musculus brain tissues development. Gene Reports 10, pages 177-183.
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Jiyuan Liu, Yunlong Wu, Qizhang Wang, Xian Liu, Xuejuan Liao & Jian Pan. (2018) Bioinformatic analysis of PFN2 dysregulation and its prognostic value in head and neck squamous carcinoma . Future Oncology 14:5, pages 449-459.
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Sara Luscieti, Bruno Galy, Lucia Gutierrez, Michael Reinke, Jorge Couso, Maya ShvartsmanAntonio Di Pascale, Walter WitkeMatthias W. Hentze, Pietro Pilo Boyl & Mayka Sanchez. (2017) The actin-binding protein profilin 2 is a novel regulator of iron homeostasis. Blood 130:17, pages 1934-1945.
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Naila Tariq, Zarrin Basharat, Saba Butt & Deeba Noreen Baig. (2016) Distribution analysis of profilin isoforms at transcript resolution with mRNA-seq and secondary structure in various organs of Rattus norvegicus. Gene 589:1, pages 49-55.
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Jana Kralovicova, Marcin Knut, Nicholas C. P. Cross & Igor Vorechovsky. (2015) Identification of U2AF(35)-dependent exons by RNA-Seq reveals a link between 3′ splice-site organization and activity of U2AF-related proteins. Nucleic Acids Research 43:7, pages 3747-3763.
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Stefanie K. Schweinhuber, Tania Meßerschmidt, Robert Hänsch, Martin Korte & Martin Rothkegel. (2015) Profilin Isoforms Modulate Astrocytic Morphology and the Motility of Astrocytic Processes. PLOS ONE 10:1, pages e0117244.
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Carlos M. Loya, Elizabeth M. McNeill, Hong Bao, Bing Zhang & David Van Vactor. (2014) miR-8 controls synapse structure by repression of the actin regulator Enabled. Development 141:9, pages 1864-1874.
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Laura MontaniTina Buerki-ThurnherrJoana Paes de FariaJorge A. PereiraNuno G. DiasRui FernandesAna F. GonçalvesAttila BraunYves BenningerRalph T. BöttcherMercedes CostellKlaus-Armin NaveRobin J. M. FranklinDies MeijerUeli SuterJoão B. Relvas. (2014) Profilin 1 is required for peripheral nervous system myelination. Development 141:7, pages 1553-1561.
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Jose C. Jimenez-Lopez, María I. Rodríguez-García & Juan D. Alché. (2013) Analysis of the Effects of Polymorphism on Pollen Profilin Structural Functionality and the Generation of Conformational, T- and B-Cell Epitopes. PLoS ONE 8:10, pages e76066.
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Zhijie Ding & Partha Roy. (2013) Profilin-1 versus profilin-2: two faces of the same coin?. Breast Cancer Research 15:3.
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