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Molecular and Cellular Biology Volume 21, 2001 - Issue 12
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Cell Growth and Development

Characterization of mec1 Kinase-Deficient Mutants and of New Hypomorphic mec1 Alleles Impairing Subsets of the DNA Damage Response Pathway

Vera PaciottiDipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano-Bicocca, 20126Milan, Italy
,
Michela ClericiDipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano-Bicocca, 20126Milan, Italy
,
Maddalena ScottiDipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano-Bicocca, 20126Milan, Italy
,
Giovanna LucchiniDipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano-Bicocca, 20126Milan, Italy
&
Maria Pia LongheseDipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano-Bicocca, 20126Milan, ItalyCorrespondence[email protected]
Pages 3913-3925 | Received 13 Nov 2000, Accepted 28 Mar 2001, Published online: 28 Mar 2023

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Elias A. Tannous & Peter M. Burgers. (2021) Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM). Critical Reviews in Biochemistry and Molecular Biology 56:5, pages 441-454.
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Lisa Hang & Xiaolan Zhao. (2016) The Rtt107 BRCT scaffold and its partner modification enzymes collaborate to promote replication. Nucleus 7:4, pages 346-351.
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Laura C Roseaulin, Chiaki Noguchi & Eishi Noguchi. (2013) Proteasome-dependent degradation of replisome components regulates faithful DNA replication. Cell Cycle 12:16, pages 2564-2569.
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Nicola Manfrini, Elisa Gobbini, Veronica Baldo, Camilla Trovesi, Giovanna Lucchini & Maria Pia Longhese. (2012) G1/S and G2/M Cyclin-Dependent Kinase Activities Commit Cells to Death in the Absence of the S-Phase Checkpoint. Molecular and Cellular Biology 32:24, pages 4971-4985.
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Vincent Archambault, Amy E. Ikui, Benjamin J. Drapkin & Frederick R. Cross. (2005) Disruption of Mechanisms That Prevent Rereplication Triggers a DNA Damage Response. Molecular and Cellular Biology 25:15, pages 6707-6721.
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Michela Clerici, Veronica Baldo, Davide Mantiero, Francisca Lottersberger, Giovanna Lucchini & Maria Pia Longhese. (2004) A Tel1/MRX-Dependent Checkpoint Inhibits the Metaphase-to-Anaphase Transition after UV Irradiation in the Absence of Mec1. Molecular and Cellular Biology 24:23, pages 10126-10144.
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Enrico Baroni, Valeria Viscardi, Hugo Cartagena-Lirola, Giovanna Lucchini & Maria Pia Longhese. (2004) The Functions of Budding Yeast Sae2 in the DNA Damage Response Require Mec1- and Tel1-Dependent Phosphorylation. Molecular and Cellular Biology 24:10, pages 4151-4165.
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Yael Aylon & Martin Kupiec. (2003) The Checkpoint Protein Rad24 of Saccharomyces cerevisiae Is Involved in Processing Double-Strand Break Ends and in Recombination Partner Choice. Molecular and Cellular Biology 23:18, pages 6585-6596.
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Vladimir I. Bashkirov, Elena V. Bashkirova, Edwin Haghnazari & Wolf-Dietrich Heyer. (2003) Direct Kinase-to-Kinase Signaling Mediated by the FHA Phosphoprotein Recognition Domain of the Dun1 DNA Damage Checkpoint Kinase. Molecular and Cellular Biology 23:4, pages 1441-1452.
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Jiyu Xin, Zhu Xu, Xuejuan Wang, Yanhua Tian, Zhihui Zhang & Gang Cai. (2019) Structural basis of allosteric regulation of Tel1/ATM kinase. Cell Research 29:8, pages 655-665.
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