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Transcriptional Regulation

The p65 (RelA) Subunit of NF-κB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression

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Pages 7065-7077 | Received 29 Jun 2001, Accepted 11 Jul 2001, Published online: 27 Mar 2023

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Yang Wu, Juan Dou, Xing Wan, Yan Leng, Xuke Liu, Lili Chen, Qianni Shen, Bo Zhao, Qingtao Meng & Jiabao Hou. (2019) Histone Deacetylase Inhibitor MS-275 Alleviates Postoperative Cognitive Dysfunction in Rats by Inhibiting Hippocampal Neuroinflammation. Neuroscience 417, pages 70-80.
Crossref
Nafiseh Falsafi, Tahereh Soleimani, Hossein Fallahi & Mehri Azadbakht. (2019) Regulatory networks upon neurogenesis induction in PC12 cell line by small molecules. Journal of Cellular Physiology 234:10, pages 18813-18824.
Crossref
Ridhima Wadhwa, Taru Aggarwal, Vamshikrishna Malyla, Nitesh Kumar, Gaurav Gupta, Dinesh Kumar Chellappan, Harish Dureja, Meenu Mehta, Saurabh Satija, Monica Gulati, Pawan Kumar Maurya, Trudi Collet, Philip Michael Hansbro & Kamal Dua. (2019) Identification of biomarkers and genetic approaches toward chronic obstructive pulmonary disease. Journal of Cellular Physiology 234:10, pages 16703-16723.
Crossref
Fang Kui, Hui Ye, Xi‐Ling Chen & Jun Zhang. (2019) Microarray meta‐analysis identifies candidate genes for human spermatogenic arrest. Andrologia 51:8.
Crossref
Jae Young Lee, Shebli Mehrazarin, Abdullah Alshaikh, Sol Kim, Wei Chen, Renate Lux, Yousang Gwack, Reuben H. Kim & Mo K. Kang. (2019) Histone Lys demethylase KDM3C demonstrates anti‐inflammatory effects by suppressing NF‐κB signaling and osteoclastogenesis. The FASEB Journal 33:9, pages 10515-10527.
Crossref
Seo-Hyun Choi, Min-Young Kim, Young-So Yoon, Dong-In Koh, Min-Kyeong Kim, Su-Yeon Cho, Kyung-Sup Kim & Man-Wook Hur. (2019) Hypoxia-induced RelA/p65 derepresses SLC16A3 (MCT4) by downregulating ZBTB7A. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862:8, pages 771-785.
Crossref
Xiaopeng Peng, Guochao Liao, Pinghua Sun, Zhiqiang Yu & Jianjun Chen. (2019) An Overview of HDAC Inhibitors and their Synthetic Routes. Current Topics in Medicinal Chemistry 19:12, pages 1005-1040.
Crossref
Derya Kabacaoglu, Dietrich A. Ruess, Jiaoyu Ai & Hana Algül. (2019) NF-κB/Rel Transcription Factors in Pancreatic Cancer: Focusing on RelA, c-Rel, and RelB. Cancers 11:7, pages 937.
Crossref
Niraj Kumar Jha, Saurabh Kumar Jha, Rohan Kar, Parma Nand, Kumari Swati & Vineet Kumar Goswami. (2019) Nuclear factor‐kappa β as a therapeutic target for Alzheimer's disease. Journal of Neurochemistry 150:2, pages 113-137.
Crossref
Maral Molaei, Crissie Vandehoef & Jason Karpac. (2019) NF-κB Shapes Metabolic Adaptation by Attenuating Foxo-Mediated Lipolysis in Drosophila. Developmental Cell 49:5, pages 802-810.e6.
Crossref
Konstantinos Dimopoulos & Kirsten Grønbæk. (2019) Epigenetic therapy in hematological cancers. APMIS 127:5, pages 316-328.
Crossref
Arielis Rodríguez-Ulloa, Yassel Ramos, Aniel Sánchez-Puente, Yasser Perera, Alexis Musacchio-Lasa, Jorge Fernández-de-Cossio, Gabriel Padrón, Luis J.G. López, Vladimir Besada & Silvio E. Perea. (2019) The Combination of the CIGB-300 Anticancer Peptide and Cisplatin Modulates Proteins Related to Cell Survival, DNA Repair and Metastasis in a Lung Cancer Cell Line Model. Current Proteomics 16:4, pages 338-349.
Crossref
Can Shi, Jessica Miley, Alison Nottingham, Toshifumi Morooka, Domenick A. Prosdocimo & Daniel I. Simon. (2019) Leukocyte integrin signaling regulates FOXP1 gene expression via FOXP1-IT1 long non-coding RNA-mediated IRAK1 pathway. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862:4, pages 493-508.
Crossref
Ping Gong, Yuetong Wang & Yongkui Jing. (2019) Apoptosis Induction byHistone Deacetylase Inhibitors in Cancer Cells: Role of Ku70. International Journal of Molecular Sciences 20:7, pages 1601.
Crossref
Xinghui Li, Wei Gong, Hao Wang, Tianliang Li, Kuldeep S. Attri, Robert E. Lewis, Andre C. Kalil, Fatema Bhinderwala, Robert Powers, Guowei Yin, Laura E. Herring, John M. Asara, Yu L. Lei, Xiaoyong Yang, Diego A. Rodriguez, Mao Yang, Douglas R. Green, Pankaj K. Singh & Haitao Wen. (2019) O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3. Immunity 50:3, pages 576-590.e6.
Crossref
Venkatesh Pooladanda, Sowjanya Thatikonda, Swarna Bale, Bijay Pattnaik, Dilep Kumar Sigalapalli, Nagendra Babu Bathini, Shashi Bala Singh & Chandraiah Godugu. (2019) Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation. Cell Death & Disease 10:2.
Crossref
Agata Sakowicz, Michalina Lisowska, Lidia Biesiada, Elżbieta Płuciennik, Agnieszka Gach, Magda Rybak-Krzyszkowska, Hubert Huras, Bartosz Sakowicz, Hanna Romanowicz, Agnieszka W. Piastowska-Ciesielska, Mariusz Grzesiak & Tadeusz Pietrucha. (2019) Placental Expression of NEMO Protein in Normal Pregnancy and Preeclampsia. Disease Markers 2019, pages 1-12.
Crossref
Xian Zhang, En Shi, Lan Yang, Weina Fu, Feng Hu & Xisong Zhou. (2019) Gentiopicroside attenuates diabetic retinopathy by inhibiting inflammation, oxidative stress, and NF-κB activation in rat model. European Journal of Inflammation 17, pages 205873921984783.
Crossref
Qisheng Zuo, Chen Zhang, Kai Jin, Jin Jing, Changhua Sun, Mahmoud F. Ahmed, Jiuzhou Song, Yani Zhang, Guohong Chen & Bichun Li. (2018) NICD-mediated notch transduction regulates the different fate of chicken primordial germ cells and spermatogonial stem cells. Cell & Bioscience 8:1.
Crossref
Yan Li, Mi Zhou, Xiuying Lv, Lina Song, Di Zhang, Yan He, Mian Wang, Xue Zhao, Xiaoqing Yuan, Guixiu Shi & Dashan Wang. (2018) Reduced Activity of HDAC3 and Increased Acetylation of Histones H3 in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis. Journal of Immunology Research 2018, pages 1-10.
Crossref
Joo Hyun Kim, Abigail Lukowicz, Wenhui Qu, Andrea Johnson & Marija Cvetanovic. (2018) Astroglia contribute to the pathogenesis of spinocerebellar ataxia Type 1 (SCA1) in a biphasic, stage-of-disease specific manner. Glia 66:9, pages 1972-1987.
Crossref
Sabrina Stebe-Frick, Maureen J. Ostaff, Eduard F. Stange, Nisar P. Malek & Jan Wehkamp. (2018) Histone deacetylase-mediated regulation of the antimicrobial peptide hBD2 differs in intestinal cell lines and cultured tissue. Scientific Reports 8:1.
Crossref
Jennifer M. Peterson, David J. Wang, Vikram Shettigar, Steve R. Roof, Benjamin D. Canan, Nadine Bakkar, Jonathan Shintaku, Jin-Mo Gu, Sean C. Little, Nivedita M. Ratnam, Priya Londhe, Leina Lu, Christopher E. Gaw, Jennifer M. Petrosino, Sandya Liyanarachchi, Huating Wang, Paul M. L. Janssen, Jonathan P. Davis, Mark T. Ziolo, Sudarshana M. Sharma & Denis C. Guttridge. (2018) NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model. Nature Communications 9:1.
Crossref
Yuyan Tan, Elaine Delvaux, Jennifer Nolz, Paul D. Coleman, Shengdi Chen & Diego Mastroeni. (2018) Upregulation of histone deacetylase 2 in laser capture nigral microglia in Parkinson's disease. Neurobiology of Aging 68, pages 134-141.
Crossref
Conrad P. Hodgkinson, Richard E. Pratt, Imke Kirste, Sophie Dal-Pra, John P. Cooke & Victor J. Dzau. (2018) Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B. Stem Cells 36:8, pages 1198-1209.
Crossref
Qi Huang, Chaoyang Ma, Li Chen, Dan Luo, Rui Chen & Fengxia Liang. (2018) Mechanistic Insights Into the Interaction Between Transcription Factors and Epigenetic Modifications and the Contribution to the Development of Obesity. Frontiers in Endocrinology 9.
Crossref
Meng Li, Betty C.A.M. van Esch, Gerry T.M. Wagenaar, Johan Garssen, Gert Folkerts & Paul A.J. Henricks. (2018) Pro- and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells. European Journal of Pharmacology 831, pages 52-59.
Crossref
Teresa C. Calegari‐Silva, Áislan C. Vivarini, Renata de M. S. Pereira, Karina L. Dias‐Teixeira, Carolina T. Rath, Amanda S. S. Pacheco, Gabrielle B. L. Silva, Charlene A. S. Pinto, José V. dos Santos, Alessandra M. Saliba, Carlos E. P. Corbett, Claudia M. Castro Gomes, Nicolas Fasel & Ulisses G. Lopes. (2018) Leishmania amazonensis downregulates macrophage iNOS expression via Histone Deacetylase 1 (HDAC1): a novel parasite evasion mechanism . European Journal of Immunology 48:7, pages 1188-1198.
Crossref
Evelyne Collignon, Annalisa CanaleClémence Al Wardi, Martin BizetEmilie Calonne, Sarah DedeurwaerderSoizic GaraudCéline NaveauxWhitney BarhamAndrew WilsonSophie BouchatPascale Hubert, Carine Van LintFiona YullChristos SotiriouKaren Willard-Gallo, Agnès NoelFrançois Fuks. (2018) Immunity drives TET1 regulation in cancer through NF-κB . Science Advances 4:6.
Crossref
Fang-Zhou Jiao, Yao Wang, Hai-Yue Zhang, Wen-bin Zhang, Lu-Wen Wang & Zuo-Jiong Gong. (2018) Histone Deacetylase 2 Inhibitor CAY10683 Alleviates Lipopolysaccharide Induced Neuroinflammation Through Attenuating TLR4/NF-κB Signaling Pathway. Neurochemical Research 43:6, pages 1161-1170.
Crossref
Christine M. Gross, Manuela Kellner, Ting Wang, Qing Lu, Xutong Sun, Evgeny A. Zemskov, Satish Noonepalle, Archana Kangath, Sanjiv Kumar, Manuel Gonzalez-Garay, Ankit A. Desai, Saurabh Aggarwal, Boris Gorshkov, Christina Klinger, Alexander D. Verin, John D. Catravas, Jeffrey R. Jacobson, Jason X.-J. Yuan, Ruslan Rafikov, Joe G. N. Garcia & Stephen M. Black. (2018) LPS-induced Acute Lung Injury Involves NF-κB–mediated Downregulation of SOX18. American Journal of Respiratory Cell and Molecular Biology 58:5, pages 614-624.
Crossref
Bahar Miraghazadeh & Matthew C. Cook. (2018) Nuclear Factor-kappaB in Autoimmunity: Man and Mouse. Frontiers in Immunology 9.
Crossref
Ivana Vancurova, Mohammad M. Uddin, Yue Zou & Ales Vancura. (2018) Combination Therapies Targeting HDAC and IKK in Solid Tumors. Trends in Pharmacological Sciences 39:3, pages 295-306.
Crossref
Xiao-Yan Bai, Shujing Li, Miao Wang, Xiahui Li, Yangyang Yang, Zhaowei Xu, Bowen Li, Yanan Li, Kangkai Xia, Huan Chen & Huijian Wu. (2018) Krüppel-like factor 9 down-regulates matrix metalloproteinase 9 transcription and suppresses human breast cancer invasion. Cancer Letters 412, pages 224-235.
Crossref
Yang-Nan Ding, Xiaoqiang Tang, Hou-Zao Chen & De-Pei Liu. 2018. Aging and Aging-Related Diseases. Aging and Aging-Related Diseases 55 75 .
Linghua Chen, Yining Huang, Ming Xu, Zuxin Cheng & Jingui Zheng. (2017) Proteomic Analysis Reveals Coordinated Regulation of Anthocyanin Biosynthesis through Signal Transduction and Sugar Metabolism in Black Rice Leaf. International Journal of Molecular Sciences 18:12, pages 2722.
Crossref
Bryan Serrels, Niamh McGivern, Marta CanelAdam Byron, Sarah C. Johnson, Henry J. McSorleyNiall Quinn, David Taggart, Alex Von KreigsheimStephen M. AndertonAlan Serrels & Margaret C. Frame. (2017) IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks. Science Signaling 10:508.
Crossref
Christina L. Lamparter, Nicola A. Philbrook & Louise M. Winn. (2017) Valproic acid increases NF-κB transcriptional activation despite decreasing DNA binding ability in P19 cells, which may play a role in VPA-initiated teratogenesis. Reproductive Toxicology 74, pages 32-39.
Crossref
Hua-Fei Deng, Xiao-Li Wang, Hui Sun & Xian-Zhong Xiao. (2017) Puerarin inhibits expression of tissue factor induced by oxidative low-density lipoprotein through activating the PI3K/Akt/eNOS pathway and inhibiting activation of ERK1/2 and NF-κB. Life Sciences 191, pages 115-121.
Crossref
Toshiaki Tanaka, Yasukazu Hozumi, Mitsuyoshi Iino & Kaoru Goto. (2017) NAP1L1 regulates NF-κB signaling pathway acting on anti-apoptotic Mcl-1 gene expression. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864:10, pages 1759-1768.
Crossref
Himavanth R. Gatla, Yue Zou, Mohammad M. Uddin & Ivana Vancurova. (2017) Epigenetic regulation of interleukin-8 expression by class I HDAC and CBP in ovarian cancer cells. Oncotarget 8:41, pages 70798-70810.
Crossref
Nisha Nagarsheth, Max S. Wicha & Weiping Zou. (2017) Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy. Nature Reviews Immunology 17:9, pages 559-572.
Crossref
Daisuke Ibi, Mario de la Fuente Revenga, Nebojsa Kezunovic, Carolina Muguruza, Justin M Saunders, Supriya A Gaitonde, José L Moreno, Maryum K Ijaz, Vishaka Santosh, Alexey Kozlenkov, Terrell Holloway, Jeremy Seto, Aintzane García-Bea, Mitsumasa Kurita, Grace E Mosley, Yan Jiang, Daniel J Christoffel, Luis F Callado, Scott J Russo, Stella Dracheva, Juan F López-Giménez, Yongchao Ge, Carlos R Escalante, J Javier Meana, Schahram Akbarian, George W Huntley & Javier González-Maeso. (2017) Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects. Nature Neuroscience 20:9, pages 1247-1259.
Crossref
Uthra Rajamani, Andrew R. Gross, Camille Ocampo, Allen M. Andres, Roberta A. Gottlieb & Dhruv Sareen. (2017) RETRACTED ARTICLE:Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives. Nature Communications 8:1.
Crossref
Arunava Bandyopadhaya, Amy Tsurumi & Laurence G. Rahme. (2017) NF-κBp50 and HDAC1 Interaction Is Implicated in the Host Tolerance to Infection Mediated by the Bacterial Quorum Sensing Signal 2-Aminoacetophenone. Frontiers in Microbiology 8.
Crossref
Mi Jeong Kim, Won Sam Kim, Dong Oh Kim, Jae-Eun Byun, Hangsak Huy, Soo Yun Lee, Hae Young Song, Young-Jun Park, Tae-Don Kim, Suk Ran Yoon, Eun-Ji Choi, Hyunjung Ha, Haiyoung Jung & Inpyo Choi. (2017) Macrophage migration inhibitory factor interacts with thioredoxin-interacting protein and induces NF-κB activity. Cellular Signalling 34, pages 110-120.
Crossref
Lauriane Lecoq, Luca Raiola, Philippe R. Chabot, Normand Cyr, Geneviève Arseneault, Pascale Legault & James G. Omichinski. (2017) Structural characterization of interactions between transactivation domain 1 of the p65 subunit of NF-κB and transcription regulatory factors. Nucleic Acids Research 45:9, pages 5564-5576.
Crossref
Chih Chieh Tao, Wei Lun Hsu, Yun Li Ma, Sin Jhong Cheng & Eminy HY Lee. (2017) Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer’s disease. Cell Death & Differentiation 24:4, pages 597-614.
Crossref
Niek G. J. Leus, Thea van den Bosch, Petra E. van der Wouden, Kim Krist, Maria E. Ourailidou, Nikolaos Eleftheriadis, Loes E. M. Kistemaker, Sophie Bos, Rutger A. F. Gjaltema, Solomon A. Mekonnen, Rainer Bischoff, Reinoud Gosens, Hidde J. Haisma & Frank J. Dekker. (2017) HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice. Scientific Reports 7:1.
Crossref
Junyu Lin, Chenjian Gu, Zhongliang Shen, Yanfeng Liu, Wei Wang, Shuai Tao, Xiaoxian Cui, Jing Liu & Youhua Xie. (2017) Hepatocyte nuclear factor 1α downregulates HBV gene expression and replication by activating the NF-κB signaling pathway. PLOS ONE 12:3, pages e0174017.
Crossref
Himavanth R. Gatla, Yue Zou, Mohammad M. Uddin, Bipradeb Singha, Pengli Bu, Ales Vancura & Ivana Vancurova. (2017) Histone Deacetylase (HDAC) Inhibition Induces IκB Kinase (IKK)-dependent Interleukin-8/CXCL8 Expression in Ovarian Cancer Cells. Journal of Biological Chemistry 292:12, pages 5043-5054.
Crossref
M Sauer, M Schuldner, N Hoffmann, A Cetintas, K S Reiners, O Shatnyeva, M Hallek, H P Hansen, S Gasser & E P von Strandmann. (2016) CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells. Oncogene 36:7, pages 933-941.
Crossref
Renu A. Kowluru & Manish Mishra. (2017) Epigenetic regulation of redox signaling in diabetic retinopathy: Role of Nrf2. Free Radical Biology and Medicine 103, pages 155-164.
Crossref
Gilson P. Dorneles, Maria Carolina R. Boeira, Lucas L. Schipper, Ivy R. V. Silva, Viviane R. Elsner, Pedro Dal Lago, Alessandra Peres & Pedro R. T. Romão. (2017) Acute Strenuous Exercise Induces an Imbalance on Histone H4 Acetylation/Histone Deacetylase 2 and Increases the Proinflammatory Profile of PBMC of Obese Individuals. Oxidative Medicine and Cellular Longevity 2017, pages 1-12.
Crossref
Hannah Wapenaar & Frank J. Dekker. (2016) Histone acetyltransferases: challenges in targeting bi-substrate enzymes. Clinical Epigenetics 8:1.
Crossref
Li Li, Dr. Tonghua Mei & Yun Zeng. (2016) HDAC2 promotes the migration and invasion of non-small cell lung cancer cells via upregulation of fibronectin. Biomedicine & Pharmacotherapy 84, pages 284-290.
Crossref
Ilangovan Raju, Gur P. Kaushal & Randy S. Haun. (2016) Epigenetic regulation of KLK7 gene expression in pancreatic and cervical cancer cells . Biological Chemistry 397:11, pages 1135-1146.
Crossref
Veronika Simko, Martina Takacova, Michaela Debreova, Katarina Laposova, Elena Ondriskova-Panisova, Silvia Pastorekova, Lucia Csaderova & Jaromir Pastorek. (2016) Dexamethasone downregulates expression of carbonic anhydrase IX via HIF-1α and NF-κB-dependent mechanisms. International Journal of Oncology 49:4, pages 1277-1288.
Crossref
Thing-Fong Tzeng, Wayne Liu, Shorong-Shii Liou, Tang-Yao Hong & I-Min Liu. (2016) Antioxidant-Rich Extract from Plantaginis Semen Ameliorates Diabetic Retinal Injury in a Streptozotocin-Induced Diabetic Rat Model. Nutrients 8:9, pages 572.
Crossref
Winfred Stacey, Shreyas Bhave & Rosalie M. Uht. (2016) Mechanisms by Which 17β-Estradiol (E2) Suppress Neuronal cox-2 Gene Expression. PLOS ONE 11:9, pages e0161430.
Crossref
James B. Hayes, Linda M. Sircy, Lauren E. Heusinkveld, Wandi Ding, Rachel N. Leander, Erin E. McClelland & David E. Nelson. (2016) Modulation of Macrophage Inflammatory Nuclear Factor κB (NF-κB) Signaling by Intracellular Cryptococcus neoformans. Journal of Biological Chemistry 291:30, pages 15614-15627.
Crossref
Tho X. PhamJi-Young Lee. (2016) Anti-Inflammatory Effect of Spirulina platensis in Macrophages Is Beneficial for Adipocyte Differentiation and Maturation by Inhibiting Nuclear Factor- κ B Pathway in 3T3-L1 Adipocytes . Journal of Medicinal Food 19:6, pages 535-542.
Crossref
Z Li, Q Hao, J Luo, J Xiong, S Zhang, T Wang, L Bai, W Wang, M Chen, W Wang, L Gu, K Lv & J Chen. (2015) USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2. Oncogene 35:22, pages 2902-2912.
Crossref
Gilson Pires Dorneles, Ivy Reichert Vital da Silva, Arthiese Korb, Karine Bertoldi, Ionara Rodrigues Siqueira, Viviane Rostirola Elsner, Pedro Roosevelt Torres Romão & Alessandra Peres. (2016) High intensity interval exercise enhances the global HDAC activity in PBMC and anti-inflammatory cytokines of overweight-obese subjects. Obesity Medicine 2, pages 25-30.
Crossref
Timothy L. Chen, Nikhil Gupta, Amy Lehman, Amy S. Ruppert, Lianbo Yu, Christopher C. Oakes, Rainer Claus, Christoph Plass, Kami J. Maddocks, Leslie Andritsos, Jeffery A. Jones, David M. Lucas, Amy J. Johnson, John C. Byrd & Erin Hertlein. (2016) Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia. Oncotarget 7:19, pages 28684-28696.
Crossref
Niek G.J. Leus, Petra E. van der Wouden, Thea van den Bosch, Wouter T.R. Hooghiemstra, Maria E. Ourailidou, Loes E.M. Kistemaker, Rainer Bischoff, Reinoud Gosens, Hidde J. Haisma & Frank J. Dekker. (2016) HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. Biochemical Pharmacology 108, pages 58-74.
Crossref
Olga Villamizar, Christopher B. Chambers, Yin-Yuan Mo, Donald S. Torry, Reese Hofstrand, Janice M. Riberdy, Derek A. Persons & Andrew Wilber. (2016) Fas-antisense long noncoding RNA is differentially expressed during maturation of human erythrocytes and confers resistance to Fas-mediated cell death. Blood Cells, Molecules, and Diseases 58, pages 57-66.
Crossref
Natarajan Balasubramaniyan, Meenakshisundaram Ananthanarayanan & Frederick J. Suchy. (2016) Nuclear factor-κB regulates the expression of multiple genes encoding liver transport proteins. American Journal of Physiology-Gastrointestinal and Liver Physiology 310:8, pages G618-G628.
Crossref
Daniela Börnigen, Svitlana Tyekucheva, Xiaodong Wang, Jennifer R. Rider, Gwo-Shu Lee, Lorelei A. Mucci, Christopher Sweeney & Curtis Huttenhower. (2016) Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer. PLOS Computational Biology 12:4, pages e1004820.
Crossref
Si Han Sherman Ho, Azhar Ali, Tan Min Chin & Mei Lin Go. (2016) Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NF-κB pathway. Oncotarget 7:10, pages 11625-11636.
Crossref
Maartje C P Cleophas, Tania O Crişan, Heidi Lemmers, Helga Toenhake-Dijkstra, Gianluca Fossati, Tim L Jansen, Charles A Dinarello, Mihai G Netea & Leo A B Joosten. (2016) Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases. Annals of the Rheumatic Diseases 75:3, pages 593-600.
Crossref
Toshiaki Tanaka & Mitsuyoshi Iino. (2016) Nuclear Translocation of p65 is Controlled by Sec6 via the Degradation of IκBα. Journal of Cellular Physiology 231:3, pages 719-730.
Crossref
Olga Ruiz-Andres, Beatriz Suarez-Alvarez, Cristina Sánchez-Ramos, Maria Monsalve, Maria D. Sanchez-Niño, Marta Ruiz-Ortega, Jesús Egido, Alberto Ortiz & Ana B. Sanz. (2016) The inflammatory cytokine TWEAK decreases PGC-1α expression and mitochondrial function in acute kidney injury. Kidney International 89:2, pages 399-410.
Crossref
Dandan Liu, Jordan T. Perkins & Bernhard Hennig. (2016) EGCG prevents PCB-126-induced endothelial cell inflammation via epigenetic modifications of NF-κB target genes in human endothelial cells. The Journal of Nutritional Biochemistry 28, pages 164-170.
Crossref
Ali Ahmadzadeh-Amiri & Ahmad Ahmadzadeh-Amiri. (2016) Epigenetic Diabetic Vascular Complications. Journal of Pediatrics Review In Press:In Press.
Crossref
Chunting Tan, Lingling Xuan, Shuhua Cao, Ganggang Yu, Qi Hou & Haoyan Wang. (2016) Decreased Histone Deacetylase 2 (HDAC2) in Peripheral Blood Monocytes (PBMCs) of COPD Patients. PLOS ONE 11:1, pages e0147380.
Crossref
Elizabeth E. Hull, McKale R. Montgomery & Kathryn J. Leyva. (2016) HDAC Inhibitors as Epigenetic Regulators of the Immune System: Impacts on Cancer Therapy and Inflammatory Diseases. BioMed Research International 2016, pages 1-15.
Crossref
Adam Jerzy Białas, Przemysław Sitarek, Joanna Miłkowska-Dymanowska, Wojciech Jerzy Piotrowski & Paweł Górski. (2016) The Role of Mitochondria and Oxidative/Antioxidative Imbalance in Pathobiology of Chronic Obstructive Pulmonary Disease. Oxidative Medicine and Cellular Longevity 2016, pages 1-15.
Crossref
Maria E. Ourailidou, Niek G. J. Leus, Kim Krist, Alessia Lenoci, Antonello Mai & Frank J. Dekker. (2016) Chemical epigenetics to assess the role of HDAC1–3 inhibition in macrophage pro-inflammatory gene expression. MedChemComm 7:11, pages 2184-2190.
Crossref
Xuexin Yu, Lin Feng, Zujing Han, Bo Wu, Shuyuan Wang, Yun Xiao, Feng Li, Lianfeng Zhang, Bangrong Cao, Xuebing Di, Dan Lu, Xia Li, Wei Jiang, Kaitai Zhang & Shujun Cheng. (2016) Crosstalk of dynamic functional modules in lung development of rhesus macaques. Molecular BioSystems 12:4, pages 1342-1349.
Crossref
Lakshmi Kuttippurathu, Biswanath Patra, Jan B. Hoek & Rajanikanth Vadigepalli. (2016) A novel comparative pattern count analysis reveals a chronic ethanol-induced dynamic shift in immediate early NF-κB genome-wide promoter binding during liver regeneration. Molecular BioSystems 12:3, pages 1037-1056.
Crossref
A.R. Maiuri & H.M. O’Hagan. 2016. Molecular and Cellular Changes in the Cancer Cell. Molecular and Cellular Changes in the Cancer Cell 69 117 .
H. Wapenaar & F.J. Dekker. 2016. Medical Epigenetics. Medical Epigenetics 685 704 .
Thea van den Bosch, Niek G.J. Leus, Tirza Timmerman & Frank J. Dekker. 2016. Drug Discovery in Cancer Epigenetics. Drug Discovery in Cancer Epigenetics 191 208 .
Christine V. Möser & Ellen Niederberger. 2016. Compendium of Inflammatory Diseases. Compendium of Inflammatory Diseases 976 986 .
Daniel Vitt, Roland Baumgartner & Hella Kohlhof. 2015. Epigenetics for Drug Discovery. Epigenetics for Drug Discovery 96 126 .
A. Takahashi, M.C. de Andrés, K. Hashimoto, E. Itoi & R.O.C. Oreffo. (2015) Epigenetic regulation of interleukin-8, an inflammatory chemokine, in osteoarthritis. Osteoarthritis and Cartilage 23:11, pages 1946-1954.
Crossref
Inhwa Hwang, Eunju Lee, Seon-A Jeon & Je-Wook Yu. (2015) Histone deacetylase 6 negatively regulates NLRP3 inflammasome activation. Biochemical and Biophysical Research Communications 467:4, pages 973-978.
Crossref
Koustav Sarkar, Sanjoy Sadhukhan, Seong-Su Han & Yatin M. Vyas. (2015) SUMOylation-disrupting WAS mutation converts WASp from a transcriptional activator to a repressor of NF-κB response genes in T cells. Blood 126:14, pages 1670-1682.
Crossref
Ying-Jung Chen & Long-Sen Chang. (2015) NFκB- and AP-1-mediated DNA looping regulates matrix metalloproteinase-9 transcription in TNF-α-treated human leukemia U937 cells. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1849:10, pages 1248-1259.
Crossref
Stuart Gallagher, Jessamy Tiffen & Peter Hersey. (2015) Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy. Cancers 7:4, pages 1959-1982.
Crossref
Madhu V. SinghMichael Z. CichaDavid K. MeyerholzMark W. ChapleauFrançois M. Abboud. (2015) Dual Activation of TRIF and MyD88 Adaptor Proteins by Angiotensin II Evokes Opposing Effects on Pressure, Cardiac Hypertrophy, and Inflammatory Gene Expression. Hypertension 66:3, pages 647-656.
Crossref
Julia Spratte, Anne Oemus, Marek Zygmunt & Herbert Fluhr. (2015) Interferon-γ differentially modulates the impact of tumor necrosis factor-α on human endometrial stromal cells. Reproductive Biology 15:3, pages 146-153.
Crossref
Arindam Paul, Marsha Danley, Biswarup Saha, Ossama Tawfik & Soumen Paul. (2015) PKCζ Promotes Breast Cancer Invasion by Regulating Expression of E-cadherin and Zonula Occludens-1 (ZO-1) via NFκB-p65. Scientific Reports 5:1.
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Emma M. Smith, Lei Zhang, Brian A. Walker, Emma L. Davenport, Lauren I. Aronson, David Krige, Leon Hooftman, Alan H. Drummond, Gareth J. Morgan & Faith E. Davies. (2013) The combination of HDAC and aminopeptidase inhibitors is highly synergistic in myeloma and leads to disruption of the NFκB signalling pathway. Oncotarget 6:19, pages 17314-17327.
Crossref
Karim Jundi & Catherine Greene. (2015) Transcription of Interleukin-8: How Altered Regulation Can Affect Cystic Fibrosis Lung Disease. Biomolecules 5:3, pages 1386-1398.
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Y. Zhou, G.F. Wang, L. Yang, F. Liu, J.Q. Kang, R.L. Wang, W. Gu & C.Y. Wang. (2015) Treatment with 1,25(OH)2D3 induced HDAC2 expression and reduced NF-κB p65 expression in a rat model of OVA-induced asthma. Brazilian Journal of Medical and Biological Research 48:7, pages 654-664.
Crossref
Michael Lienhard SchmitzLaureano de la Vega. (2015) New Insights into the Role of Histone Deacetylases as Coactivators of Inflammatory Gene Expression. Antioxidants & Redox Signaling 23:1, pages 85-98.
Crossref
Xi Chen, Xiao-jun Guan, Xiao-hua Peng, Zhi-lei Cui, Chun-yu Luan & Xue-jun Guo. (2015) Acetylation of lysine 9 on histone H3 is associated with increased pro-inflammatory cytokine release in a cigarette smoke-induced rat model through HDAC1 depression. Inflammation Research 64:7, pages 513-526.
Crossref
Linna Li & Wenliang Li. (2015) Epithelial–mesenchymal transition in human cancer: Comprehensive reprogramming of metabolism, epigenetics, and differentiation. Pharmacology & Therapeutics 150, pages 33-46.
Crossref
Melissa J. Churchill, Daniel J. Cowley, Steve L. Wesselingh, Paul R. Gorry & Lachlan R. Gray. (2014) HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research. Journal of NeuroVirology 21:3, pages 290-300.
Crossref
Abdel-Rahman N Zekri, Zeinab Korany Hassan, Abeer A Bahnassy, Hussein M Khaled, Mahmoud N El-Rouby, Rasha M Haggag & Fouad M Abu-Taleb. (2015) Differentially Expressed Genes in Metastatic Advanced Egyptian Bladder Cancer. Asian Pacific Journal of Cancer Prevention 16:8, pages 3543-3549.
Crossref
Yong Liu, Yao Li, LiMin Zhang, MingQiang Li, Chao Li, ChengBiao Xue, Xia Huang & Ping Zhou. (2015) NF-κB Downregulates Cbl-b through Binding and Suppressing Cbl-b Promoter in T Cell Activation. The Journal of Immunology 194:8, pages 3778-3783.
Crossref

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