Advanced search
Publication Cover
Molecular and Cellular Biology Volume 22, 2002 - Issue 4
Submit an article Journal homepage
378
Views
1,274
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway

Eek-hoon Jho1 Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, New York10032;2 Laboratory of Ophthalmology and Visual Science, Catholic University Medical College, Seoul137-701, Korea
,
Tong Zhang1 Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, New York10032
,
Claire Domon3 INSERM Unit 381, F-67200Strasbourg, France
,
Choun-Ki Joo2 Laboratory of Ophthalmology and Visual Science, Catholic University Medical College, Seoul137-701, Korea
,
Jean-Noel Freund3 INSERM Unit 381, F-67200Strasbourg, France
&
Frank Costantini1 Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, New York10032Correspondence[email protected]
Pages 1172-1183 | Received 17 Sep 2001, Accepted 16 Nov 2001, Published online: 28 Mar 2023

Citations (1274)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (32)

Joseph R. Chitwood, Nabarun Chakraborty, Rasha Hammamieh, Sharon M. Moe, Neal X. Chen, Melissa A. Kacena & Roman M. Natoli. (2021) Predicting fracture healing with blood biomarkers: the potential to assess patient risk of fracture nonunion. Biomarkers 26:8, pages 703-717.
Read now
Pin Lv & Yuan Xue. (2021) ETS like-1 protein ELK1-induced lncRNA LINC01638 accelerates the progression of papillary thyroid cancer by regulating Axin2 through Wnt/β-catenin signaling pathway. Bioengineered 12:1, pages 3873-3885.
Read now
Xiumei Zhang, Yalan Luo & Qingchang Li. (2020) TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling. OncoTargets and Therapy 13, pages 5819-5830.
Read now
Qian Li, Yue Hua, Yilin Yang, Xinyu He, Wei Zhu, Jiyong Wang & Xiaoqing Gan. (2018) T Cell Factor 7 (TCF7)/TCF1 Feedback Controls Osteocalcin Signaling in Brown Adipocytes Independent of the Wnt/β-Catenin Pathway. Molecular and Cellular Biology 38:7.
Read now
Lorenza González-Mariscal, Arturo Raya-Sandino, Laura González-González & Christian Hernández-Guzmán. (2018) Relationship between G proteins coupled receptors and tight junctions. Tissue Barriers 6:1.
Read now
Takeshi Shimizu, Ron Smits & Kazuhiro Ikenaka. (2016) Microglia-Induced Activation of Noncanonical Wnt Signaling Aggravates Neurodegeneration in Demyelinating Disorders. Molecular and Cellular Biology 36:21, pages 2728-2741.
Read now
Ilaria Spadoni, Alessandro Pietrelli, Graziano Pesole & Maria Rescigno. (2016) Gene expression profile of endothelial cells during perturbation of the gut vascular barrier. Gut Microbes 7:6, pages 540-548.
Read now
Amit Kumar, Ravindra B. Chalamalasetty, Mark W. Kennedy, Sara Thomas, Shreya N. Inala, Robert J. Garriock & Terry P. Yamaguchi. (2016) Zfp703 Is a Wnt/β-Catenin Feedback Suppressor Targeting the β-Catenin/Tcf1 Complex. Molecular and Cellular Biology 36:12, pages 1793-1802.
Read now
Iyoko Katoh, Nahoko Fukunishi, Masahiro Fujimuro, Hirotake Kasai, Kohji Moriishi, Ryu-Ichiro Hata & Shun-ichi Kurata. (2016) Repression of Wnt/β-catenin response elements by p63 (TP63). Cell Cycle 15:5, pages 699-710.
Read now
Xunxian Liu, Xinyue Lu, Kaimei Song & Marc R. Blackman. (2016) Natural Functions of PLIN2 Mediating Wnt/LiCl Signaling and Glycogen Synthase Kinase 3 (GSK3)/GSK3 Substrate-Related Effects Are Modulated by Lipid. Molecular and Cellular Biology 36:3, pages 421-437.
Read now
Saviz Ehyai, Mathew G. Dionyssiou, Joseph W. Gordon, Declan Williams, K. W. Michael Siu & John C. McDermott. (2016) A p38 Mitogen-Activated Protein Kinase-Regulated Myocyte Enhancer Factor 2–β-Catenin Interaction Enhances Canonical Wnt Signaling. Molecular and Cellular Biology 36:2, pages 330-346.
Read now
Vasco Marcato, Lionel Luron, Lucie M. Laqueuvre, Dominique Simon, Zeyni Mansuroglu, Marie Flamand, Jean-Jacques Panthier, Sylvie Souès, Charbel Massaad & Eliette Bonnefoy. (2016) β-Catenin Upregulates the Constitutive and Virus-Induced Transcriptional Capacity of the Interferon Beta Promoter through T-Cell Factor Binding Sites. Molecular and Cellular Biology 36:1, pages 13-29.
Read now
AnYuan Zhong, Xue Pan, MinHua Shi & HuaJun Xu. (2015) −148 C/T polymorphism of Axin2 contributes to a decreased risk of cancer: evidence from a meta-analysis. OncoTargets and Therapy 8, pages 1957-1966.
Read now
Yuxuan Xia & Shaoping Wu. (2015) Tissue inhibitor of metalloproteinase 2 inhibits activation of the β-catenin signaling in melanoma cells. Cell Cycle 14:11, pages 1666-1674.
Read now
Angela Anderegg & Rajeshwar Awatramani. (2015) Making a mes: A transcription factor-microRNA pair governs the size of the midbrain and the dopaminergic progenitor pool. Neurogenesis 2:1.
Read now
Xiang Hua Han, Yong-Ri Jin, Leonard Tan, Tatiana Kosciuk, Jin-Seon Lee & Jeong Kyo Yoon. (2014) Regulation of the Follistatin Gene by RSPO-LGR4 Signaling via Activation of the WNT/β-Catenin Pathway in Skeletal Myogenesis. Molecular and Cellular Biology 34:4, pages 752-764.
Read now
Jung Hur & Sunjoo Jeong. (2013) Multitasking β-catenin: from adhesion and transcription to RNA regulation. Animal Cells and Systems 17:5, pages 299-305.
Read now
Nam Hee Kim, Yong Hoon Cha, Shi Eun Kang, Yoon Mi Lee, Inhan Lee, So Young Cha, Joo Kyung Ryu, Jung Min Na, Changbum Park, HoGeun Yoon, Gyeong-Ju Park, Jong In Yook & Hyun Sil Kim. (2013) p53 regulates nuclear GSK-3 levels through miR-34-mediated Axin2 suppression in colorectal cancer cells. Cell Cycle 12:10, pages 1578-1587.
Read now
I-Ching Wang, Jonathan Snyder, Yufang Zhang, Julie Lander, Yuto Nakafuku, James Lin, Gang Chen, Tanya V. Kalin, Jeffrey A. Whitsett & Vladimir V. Kalinichenko. (2012) Foxm1 Mediates Cross Talk between Kras/Mitogen-Activated Protein Kinase and Canonical Wnt Pathways during Development of Respiratory Epithelium. Molecular and Cellular Biology 32:19, pages 3838-3850.
Read now
Fumitaka Inoue, Daisuke Kurokawa, Maiko Takahashi & Shinichi Aizawa. (2012) Gbx2 Directly Restricts Otx2 Expression to Forebrain and Midbrain, Competing with Class III POU Factors. Molecular and Cellular Biology 32:13, pages 2618-2627.
Read now
Juan P. Parody, Maria L. Alvarez, Ariel D. Quiroga, Maria P. Ceballos, Daniel E. Frances, Gerardo B. Pisani, Jose M. Pellegrino, Cristina E. Carnovale & Maria C. Carrillo. (2010) Attenuation of the Wnt/β-catenin/TCF pathway by in vivo interferon-α2b (IFN-α2b) treatment in preneoplastic rat livers. Growth Factors 28:3, pages 166-177.
Read now
Ina Kramer, Christine Halleux, Hansjoerg Keller, Marco Pegurri, Jonathan H. Gooi, Patricia Brander Weber, Jian Q. Feng, Lynda F. Bonewald & Michaela Kneissel. (2010) Osteocyte Wnt/β-Catenin Signaling Is Required for Normal Bone Homeostasis. Molecular and Cellular Biology 30:12, pages 3071-3085.
Read now
Yosuke Funato & Hiroaki Miki. (2010) Redox regulation of Wnt signalling via nucleoredoxin. Free Radical Research 44:4, pages 379-388.
Read now
Anthony V Nguyen, Micaela Martinez, Michael J Stamos, Mary P Moyer, Kestutis Planutis, Christopher Hope & Randall F Holcombe. (2009) Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer. Cancer Management and Research 1, pages 25-37.
Read now
Kristina Ellwanger, Hiroaki Saito, Philippe Clément-Lacroix, Nicole Maltry, Joachim Niedermeyer, Woon Kyu Lee, Roland Baron, Georges Rawadi, Heiner Westphal & Christof Niehrs. (2008) Targeted Disruption of the Wnt Regulator Kremen Induces Limb Defects and High Bone Density. Molecular and Cellular Biology 28:15, pages 4875-4882.
Read now
Claudio Sustmann, Henrik Flach, Hanna Ebert, Quinn Eastman & Rudolf Grosschedl. (2008) Cell-Type-Specific Function of BCL9 Involves a Transcriptional Activation Domain That Synergizes with β-Catenin. Molecular and Cellular Biology 28:10, pages 3526-3537.
Read now
Pantelis Hatzis, Laurens G. van der Flier, Marc A. van Driel, Victor Guryev, Fiona Nielsen, Sergei Denissov, Isaäc J. Nijman, Jan Koster, Evan E. Santo, Willem Welboren, Rogier Versteeg, Edwin Cuppen, Marc van de Wetering, Hans Clevers & Hendrik G. Stunnenberg. (2008) Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells. Molecular and Cellular Biology 28:8, pages 2732-2744.
Read now
Fawzia A. Atcha, Adeela Syed, Beibei Wu, Nate P. Hoverter, Noriko N. Yokoyama, Ju-Hui T. Ting, Jesus E. Munguia, Harry J. Mangalam, J. Lawrence Marsh & Marian L. Waterman. (2007) A Unique DNA Binding Domain Converts T-Cell Factors into Strong Wnt Effectors. Molecular and Cellular Biology 27:23, pages 8352-8363.
Read now
Simon Wöhrle, Britta Wallmen & Andreas Hecht. (2007) Differential Control of Wnt Target Genes Involves Epigenetic Mechanisms and Selective Promoter Occupancy by T-Cell Factors. Molecular and Cellular Biology 27:23, pages 8164-8177.
Read now
Ian V. Chia & Frank Costantini. (2005) Mouse Axin and Axin2/Conductin Proteins Are Functionally Equivalent In Vivo. Molecular and Cellular Biology 25:11, pages 4371-4376.
Read now
Masaaki Nishiyama, Keiko Nakayama, Ryosuke Tsunematsu, Tadasuke Tsukiyama, Akira Kikuchi & Keiichi I. Nakayama. (2004) Early Embryonic Death in Mice Lacking the β-Catenin-Binding Protein Duplin. Molecular and Cellular Biology 24:19, pages 8386-8394.
Read now
Barbara Lustig, Boris Jerchow, Martin Sachs, Sigrid Weiler, Torsten Pietsch, Uwe Karsten, Marc van de Wetering, Hans Clevers, Peter M. Schlag, Walter Birchmeier & Jürgen Behrens. (2002) Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors. Molecular and Cellular Biology 22:4, pages 1184-1193.
Read now

Articles from other publishers (1242)

Ramani Shyam Kapuganti, Bushra Hayat, Biswajit Padhy, Pranjya Paramita Mohanty & Debasmita Pankaj Alone. (2023) Dickkopf-1 and ROCK2 upregulation and associated protein aggregation in pseudoexfoliation syndrome and glaucoma. Life Sciences 326, pages 121797.
Crossref
Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Lahiru Chamara Weerasinghe Arachchige, Mirko Peitzsch, Nicole Bechmann, Sameh A. Youssef, Alain de Bruin, Elvira R. M. Bakker, Frank Claessens, Marie-Christine Chaboissier & Andreas Schedl. (2023) Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice. Disease Models & Mechanisms 16:6.
Crossref
Yura Son, W. Walter Lorenz & Chad M. Paton. (2023) Linoleic acid-induced ANGPTL4 inhibits C2C12 skeletal muscle differentiation by suppressing Wnt/β-catenin. The Journal of Nutritional Biochemistry 116, pages 109324.
Crossref
Isabella Lin, Angela Wei, Zain Awamleh, Meghna Singh, Aileen Ning, Analeyla Herrera, Bianca E. Russell, Rosanna Weksberg & Valerie A. Arboleda. (2023) Multiomics of Bohring-Opitz syndrome truncating ASXL1 mutations identify canonical and noncanonical Wnt signaling dysregulation. JCI Insight 8:10.
Crossref
Yoshifumi Tsuchiya, René B. SvenssonChing-Yan Chloé YeungPeter SchjerlingMichael Kjaer. (2023) Tensile Loaded Tissue-Engineered Human Tendon Constructs Stimulate Myotube Formation. Tissue Engineering Part A 29:9-10, pages 292-305.
Crossref
Gyusang Jeong, Seung Hyun Shin, Su Na Kim, Yongjoo Na, Byung Cheol Park, Jeong Hun Cho, Won-Seok Park & Hyoung-June Kim. (2023) Ginsenoside Re prevents 3-methyladenine-induced catagen phase acceleration by regulating Wnt/β-catenin signaling in human dermal papilla cells. Journal of Ginseng Research 47:3, pages 440-447.
Crossref
Xue-Lian Sun, Zhen-Hua Chen, Xize Guo, Jingjing Wang, Mengmeng Ge, Samuel Zheng Hao Wong, Ting Wang, Si Li, Mingze Yao, Laura A. Johnston & Qing-Feng Wu. (2023) Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development. Developmental Cell 58:9, pages 744-759.e11.
Crossref
Mushriq Al-Jazrawe, Steven Xu, Raymond Poon, Qingxia Wei, Joanna Przybyl, Sushama Varma, Matt van de Rijn & Benjamin A. Alman. (2023) CD142 Identifies Neoplastic Desmoid Tumor Cells, Uncovering Interactions Between Neoplastic and Stromal Cells That Drive Proliferation. Cancer Research Communications 3:4, pages 697-708.
Crossref
Elliot D. Kramer, Stephanie L. Tzetzo, Sean H. Colligan, Mary L. Hensen, Craig M. Brackett, Björn E. Clausen, Makoto M. Taketo & Scott I. Abrams. (2023) β-Catenin signaling in alveolar macrophages enhances lung metastasis through a TNF-dependent mechanism. JCI Insight 8:8.
Crossref
Lianqi Chen, Yan-Ping Liu, Li-Fei Tian, Mingzhou Li, Shuyu Yang, Song Wang, Wenqing Xu & Xiao-Xue Yan. (2023) Structural Basis of the Interaction between Human Axin2 and SIAH1 in the Wnt/β-Catenin Signaling Pathway. Biomolecules 13:4, pages 647.
Crossref
Kuan‐Yu Chu, Yin‐Lin Wang, Jung‐Tsu Chen, Chia‐Hui Lin, Chung‐Chen Jane Yao, Yi‐Jane Chen, Huan‐Wen Chen, James P. Simmer, Jan C.‐C. Hu & Shih‐Kai Wang. (2023) PAX9 mutations and genetic synergism in familial tooth agenesis . Annals of the New York Academy of Sciences.
Crossref
Rui Ma, Xudong Xie, Chunmei Xu, Peilei Shi, Yafei Wu & Jun Wang. (2023) Loss of β‐catenin causes cementum hypoplasia by hampering cementogenic differentiation of Axin2‐expressing cells. Journal of Periodontal Research 58:2, pages 414-421.
Crossref
Julie Leclerc, Marie Beaumont, Roseline Vibert, Stéphane Pinson, Catherine Vermaut, Cathy Flament, Tonio Lovecchio, Lucie Delattre, Christophe Demay, Florence Coulet, Erell Guillerm, Nadim Hamzaoui, Patrick R. Benusiglio, Afane Brahimi, François Cornelis, Hélène Delhomelle, Sandra Fert‐Ferrer, Benjamin P. J. Fournier, Alain Hovnanian, Clémentine Legrand, Alain Lortholary, David Malka, Florence Petit, Jean‐Christophe Saurin, Sophie Lejeune, Chrystelle Colas & Marie‐Pierre Buisine. (2022) AXIN2 germline testing in a French cohort validates pathogenic variants as a rare cause of predisposition to colorectal polyposis and cancer . Genes, Chromosomes and Cancer 62:4, pages 210-222.
Crossref
Hyeoncheol Kim, Luke B Villareal, Zhaoli Liu, Mohammad Haneef, Daniel M Falcon, David R Martin, Ho‐Joon Lee, Michael K Dame, Durga Attili, Ying Chen, James Varani, Jason R. Spence, Olga Kovbasnjuk, Justin A Colacino, Costas A. Lyssiotis, Henry C Lin, Yatrik M Shah & Xiang Xue. (2023) Transferrin Receptor‐Mediated Iron Uptake Promotes Colon Tumorigenesis. Advanced Science 10:10.
Crossref
Bani Mukhopadhyay, Kellie Holovac, Kornel Schuebel, Partha Mukhopadhyay, Resat Cinar, Sindhu Iyer, Cheryl Marietta, David Goldman & George Kunos. (2023) The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics. Cell Death Discovery 9:1.
Crossref
Sophia Beng Hui Lim, Shang Wei, Andy Hee-Meng Tan, Maurice A. M. van Steensel & Xinhong Lim. (2023) Lrig1-expressing epidermal progenitors require SCD1 to maintain the dermal papilla niche. Scientific Reports 13:1.
Crossref
Linh Vo, Michael W. Schmidtke, Nevton T. Da Rosa-Junior, Mindong Ren, Michael Schlame & Miriam L. Greenberg. (2023) Cardiolipin metabolism regulates expression of muscle transcription factor MyoD1 and muscle development. Journal of Biological Chemistry 299:3, pages 102978.
Crossref
Laura A. Dada, Lynn C. Welch, Natalia D. Magnani, Ziyou Ren, Hyebin Han, Patricia L. Brazee, Diego Celli, Annette S. Flozak, Anthea Weng, Mariana Maciel Herrerias, Vitalii Kryvenko, István Vadász, Constance E. Runyan, Hiam Abdala-Valencia, Masahiko Shigemura, S. Marina Casalino-Matsuda, Alexander V. Misharin, G.R. Scott Budinger, Cara J. Gottardi & Jacob I. Sznajder. (2023) Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells. JCI Insight 8:4.
Crossref
Megan E. Jones, Johanna Büchler, Tom Dufor, Ernest Palomer, Samuel TeoNuria Martin-Flores, Katharina BoroviakEmmanouil MetzakopianAlasdair Gibb & Patricia C. Salinas. (2023) A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease. Science Advances 9:2.
Crossref
Gengyi Zou & Jae-Il Park. (2023) Wnt signaling in liver regeneration, disease, and cancer. Clinical and Molecular Hepatology 29:1, pages 33-50.
Crossref
Zhi-Hui Zhang, Ming-Dong Liu, Kai Yao, Shen Xu, De-Xin Yu, Dong-Dong Xie & De-Xiang Xu. (2023) Vitamin D deficiency aggravates growth and metastasis of prostate cancer through promoting EMT in two β-catenin-related mechanisms. The Journal of Nutritional Biochemistry 111, pages 109177.
Crossref
Tanne van der Wal & Renée van Amerongen. 2023. Wnt Signaling in Development and Disease. Wnt Signaling in Development and Disease 61 93 .
Rony Chidiac & Stephane Angers. 2023. Wnt Signaling in Development and Disease. Wnt Signaling in Development and Disease 121 143 .
Lea Gessler, Christopher Kurtek, Mira Merholz, Yongzhi Jian & Said Hashemolhosseini. (2022) In Adult Skeletal Muscles, the Co-Receptors of Canonical Wnt Signaling, Lrp5 and Lrp6, Determine the Distribution and Size of Fiber Types, and Structure and Function of Neuromuscular Junctions. Cells 11:24, pages 3968.
Crossref
Laury Amelia Roa Fuentes, Marjon Bloemen, Carine EL Carels, Frank ADTG Wagener & Johannes W Von den Hoff. (2022) Retinoic acid effects on in vitro palatal fusion and WNT signaling. European Journal of Oral Sciences 130:6.
Crossref
Shanshan He, Ruchir Bhatt, Carl Brown, Emily A. Brown, Derek L. Buhr, Kan Chantranuvatana, Patrick Danaher, Dwayne Dunaway, Ryan G. Garrison, Gary Geiss, Mark T. Gregory, Margaret L. Hoang, Rustem Khafizov, Emily E. Killingbeck, Dae Kim, Tae Kyung Kim, Youngmi Kim, Andrew Klock, Mithra Korukonda, Alecksandr Kutchma, Zachary R. Lewis, Yan Liang, Jeffrey S. Nelson, Giang T. Ong, Evan P. Perillo, Joseph C. Phan, Tien Phan-Everson, Erin Piazza, Tushar Rane, Zachary Reitz, Michael Rhodes, Alyssa Rosenbloom, David Ross, Hiromi Sato, Aster W. Wardhani, Corey A. Williams-Wietzikoski, Lidan Wu & Joseph M. Beechem. (2022) High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging. Nature Biotechnology 40:12, pages 1794-1806.
Crossref
Laura Simonson, Ethan Oldham & Hao Chang. (2022) Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development. Development 149:22.
Crossref
Heba A. S. Bazid, Rehab Monir Samaka, Marwa E. A. Mousa & Iman Seleit. (2022) Immunohistochemical expression of Axin‐2, as an implication of the role of stem cell in scar pathogenesis and prognosis. Journal of Cosmetic Dermatology 21:11, pages 6010-6020.
Crossref
Ryoko Nagano, Shinsuke Fujii, Kana Hasegawa, Hidefumi Maeda & Tamotsu Kiyoshima. (2022) Wnt signaling promotes tooth germ development through YAP1-TGF-β signaling. Biochemical and Biophysical Research Communications 630, pages 64-70.
Crossref
Giulia Pizzolato, Lavanya Moparthi, Simon Söderholm, Claudio Cantù & Stefan Koch. (2022) The oncogenic transcription factor FOXQ1 is a differential regulator of Wnt target genes. Journal of Cell Science 135:19.
Crossref
James M. Chan, Mark Clendenning, Sharelle Joseland, Peter Georgeson, Khalid Mahmood, Romy Walker, Julia Como, Jihoon E. Joo, Susan Preston, Ryan A. Hutchinson, Bernard J. Pope, Andrew Metz, Catherine Beard, Rebecca Purvis, Julie Arnold, Varnika Vijay, Galina Konycheva, Nathan Atkinson, Susan Parry, Mark A. Jenkins, Finlay A. Macrae, Christophe Rosty, Ingrid M. Winship & Daniel D. Buchanan. (2021) Rare germline variants in the AXIN2 gene in families with colonic polyposis and colorectal cancer. Familial Cancer 21:4, pages 399-413.
Crossref
Mario Sánchez-Canteli, Luis Juesas, Irati Garmendia, María Otero-Rosales, Alfonso Calvo, Monica Alvarez-Fernández, Aurora Astudillo, Luis M. Montuenga, Juana M. García-Pedrero & Juan P. Rodrigo. (2022) Tumor-Intrinsic Nuclear β-Catenin Associates with an Immune Ignorance Phenotype and a Poorer Prognosis in Head and Neck Squamous Cell Carcinomas. International Journal of Molecular Sciences 23:19, pages 11559.
Crossref
Limin Zhou, Hongying Li, Dunlan Zhang, Lu Chen, Hong Dong, Yuqin Yuan & Tinghui Wang. (2022) OTX1 promotes tumorigenesis and progression of cervical cancer by regulating the Wnt signaling pathway. Oncology Reports 48:5.
Crossref
Jiaqi Liu, Guang Shu, Anqi Wu, Xiaojun Zhang, Zhengwei Zhou, Ayesha B. Alvero, Gil Mor & Gang Yin. (2022) TWIST1 induces proteasomal degradation of β-catenin during the differentiation of ovarian cancer stem-like cells. Scientific Reports 12:1.
Crossref
Kristýna Olbertová, Dušan Hrčkulák, Vítězslav Kříž, Wojciech Jesionek, Jan Kubovčiak, Milan Ešner, Vladimír Kořínek & Marcela Buchtová. (2022) Role of LGR5-positive mesenchymal cells in craniofacial development. Frontiers in Cell and Developmental Biology 10.
Crossref
Che-Fan Huang, Cara J. Gottardi & Milan Mrksich. (2022) Tyrosine phosphatase activity is restricted by basic charge substituting mutation of substrates. Scientific Reports 12:1.
Crossref
Mizuki Nagata, Jeryl D. English, Noriaki Ono & Wanida Ono. (2022) Diverse stem cells for periodontal tissue formation and regeneration. genesis 60:8-9.
Crossref
Jolanda J. D. de Roo, Amiet Chhatta, Laura Garcia-Perez, Brigitta A. E. Naber, Sandra A. Vloemans, Daniela C. F. Salvatori, Karin Pike-Overzet, Harald Mikkers & Frank J. T. Staal. (2022) Axin2/Conductin Is Required for Normal Haematopoiesis and T Lymphopoiesis. Cells 11:17, pages 2679.
Crossref
Qianlin Ye, Arshia Bhojwani & Jimmy K. Hu. (2022) Understanding the development of oral epithelial organs through single cell transcriptomic analysis. Development 149:16.
Crossref
Alexander Scheiter, Frederik Hierl, Ingrid Winkel, Felix Keil, Margit Klier-Richter, Cédric Coulouarn, Florian Lüke, Arne Kandulski, Matthias Evert, Wolfgang Dietmaier, Diego F. Calvisi & Kirsten Utpatel. (2022) Wnt/β-Catenin-Pathway Alterations and Homologous Recombination Deficiency in Cholangiocarcinoma Cell Lines and Clinical Samples: Towards Specific Vulnerabilities. Journal of Personalized Medicine 12:8, pages 1270.
Crossref
Jennifer Kurz, Anna-Carina Weiss, Timo H.-W. Lüdtke, Lena Deuper, Mark-Oliver Trowe, Hauke Thiesler, Herbert Hildebrandt, Joerg Heineke, Stephen A. Duncan & Andreas Kispert. (2022) GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter . Development 149:15.
Crossref
Aya Badeea Ismail, Marwan ’Mohammad Saeed’ Naji, İnci Nebih, Gulten Tuncel, Burcu Ozbakir, Sehime Gulsun Temel, Pinar Tulay, Gamze Mocan & Mahmut Cerkez Ergoren. (2022) The expression profile of WNT/β-catanin signalling genes in human oocytes obtained from polycystic ovarian syndrome (PCOS) patients. Zygote 30:4, pages 536-542.
Crossref
Khalid Saad Alharbi, Tabinda Ali, Yogendra Singh, Ahmed Saleh Ali Al-Ghamdi, Imran Kazmi, Fahad A. Al-Abbasi, Sami I. Alzarea, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Sachin Kumar Singh, Dinesh Kumar Chellappan, Kamal Dua & Gaurav Gupta. (2022) Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction. Chemico-Biological Interactions 363, pages 110020.
Crossref
Kento Takaya, Ayano Sunohara, Noriko Aramaki-Hattori, Shigeki Sakai, Keisuke Okabe, Hideko Kanazawa, Toru Asou & Kazuo Kishi. (2022) Role of Wnt Signaling in Mouse Fetal Skin Wound Healing. Biomedicines 10:7, pages 1536.
Crossref
Chiaki Horie, Chi Zhu, Kiyoshi Yamaguchi, Saya Nakagawa, Yumiko Isobe, Kiyoko Takane, Tsuneo Ikenoue, Yasunori Ohta, Yukihisa Tanaka, Susumu Aikou, Giichiro Tsurita, Yuka Ahiko, Dai Shida & Yoichi Furukawa. (2022) Motile sperm domain containing 1 is upregulated by the Wnt/β‑catenin signaling pathway in colorectal cancer. Oncology Letters 24:2.
Crossref
Ellen Youngsoo RimHans Clevers & Roel Nusse. (2022) The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators. Annual Review of Biochemistry 91:1, pages 571-598.
Crossref
Jong Hoon Won, Jacob S. Choi & Joon-Il Jun. (2022) CCN1 interacts with integrins to regulate intestinal stem cell proliferation and differentiation. Nature Communications 13:1.
Crossref
Tianyu Zhao, Moira McMahon, Kurt Reynolds, Subbroto Kumar Saha, Arjun Stokes & Chengji J. Zhou. (2022) The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice. Disease Models & Mechanisms 15:6.
Crossref
K. Wang, C. Xu, X. Xie, Y. Jing, P.J. Chen, S. Yadav, Z. Wang, R.W. Taylor, J. Wang & J.Q. Feng. (2022) Axin2+ PDL Cells Directly Contribute to New Alveolar Bone Formation in Response to Orthodontic Tension Force. Journal of Dental Research 101:6, pages 695-703.
Crossref
Laetitia Ganier, Stephane Betzi, Carine Derviaux, Philippe Roche, Charlotte Dessaux, Christophe Muller, Laurent Hoffer, Xavier Morelli & Jean-Paul Borg. (2022) Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer. ACS Chemical Biology 17:5, pages 1061-1072.
Crossref
Caroline Caetano da Silva, Thomas Edouard, Melanie Fradin, Marion Aubert-Mucca, Manon Ricquebourg, Ratish Raman, Jean Pierre Salles, Valérie Charon, Pascal Guggenbuhl, Marc Muller, Martine Cohen-Solal & Corinne Collet. (2022) WNT11, a new gene associated with early onset osteoporosis, is required for osteoblastogenesis . Human Molecular Genetics 31:10, pages 1622-1634.
Crossref
Carolina N. Franco, May M. Noe & Lauren V. Albrecht. (2022) Metabolism and Endocrine Disorders: What Wnt Wrong?. Frontiers in Endocrinology 13.
Crossref
Xiuheng Xue, Caiyun Fan, Luping Wang, Lei Gao, Kai Fan, Mengling Peng, Fugui Fang, Jianbo Cheng & Juhua Wang. (2022) Ascorbic acid regulates mouse spermatogonial stem cell proliferation in a Wnt/β-catenin/ROS signaling dependent manner. Theriogenology 184, pages 61-72.
Crossref
Yu-Hwai Tsai, Angeline Wu, Joshua H. Wu, Meghan M. Capeling, Emily M. Holloway, Sha Huang, Michael Czerwinkski, Ian Glass, Peter D.R. Higgins & Jason R. Spence. (2022) Acquisition of NOTCH dependence is a hallmark of human intestinal stem cell maturation. Stem Cell Reports 17:5, pages 1138-1153.
Crossref
Pablo Astudillo. (2022) An emergent Wnt5a/YAP/TAZ regulatory circuit and its possible role in cancer. Seminars in Cell & Developmental Biology 125, pages 45-54.
Crossref
Qun Niu, Jingjing Shi, Qing Gao & Jiang Fu. (2021) WNT5A Enhances LH-Mediated Expression of HAS2 in Granulosa Cells. Reproductive Sciences 29:5, pages 1618-1629.
Crossref
Alexandra A. Vetrova, Tatiana S. Lebedeva, Aleena A. Saidova, Daria M. Kupaeva, Yulia A. Kraus & Stanislav V. Kremnyov. (2021) From apolar gastrula to polarized larva: Embryonic development of a marine hydroid, Dynamena pumila . Developmental Dynamics 251:5, pages 795-825.
Crossref
Jian Sun, NaYoung Ha, Zhixu Liu, Qian Bian & Xudong Wang. (2022) A Neural Crest-specific Overexpression Mouse Model Reveals the Transcriptional Regulatory Effects of Dlx2 During Maxillary Process Development. Frontiers in Physiology 13.
Crossref
Henry F. Duncan, Yoshifumi Kobayashi, Yukako Yamauchi, Angela Quispe-Salcedo, Zhi Chao Feng, Jia Huang, Nicola C. Partridge, Teruyo Nakatani, Jeanine D’Armiento & Emi Shimizu. (2022) The Critical Role of MMP13 in Regulating Tooth Development and Reactionary Dentinogenesis Repair Through the Wnt Signaling Pathway. Frontiers in Cell and Developmental Biology 10.
Crossref
Gerard Llimos, Vincent Gardeux, Ute Koch, Judith F. Kribelbauer, Antonina Hafner, Daniel Alpern, Joern Pezoldt, Maria Litovchenko, Julie Russeil, Riccardo Dainese, Riccardo Moia, Abdurraouf Mokhtar Mahmoud, Davide Rossi, Gianluca Gaidano, Christoph Plass, Pavlo Lutsik, Clarissa Gerhauser, Sebastian M. Waszak, Alistair Boettiger, Freddy Radtke & Bart Deplancke. (2022) A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation. Nature Communications 13:1.
Crossref
Davide M. Coda, Harshil Patel, Ilaria Gori, Tessa E. Gaarenstroom, Ok-Ryul Song, Michael Howell & Caroline S. Hill. (2022) A network of transcription factors governs the dynamics of NODAL/Activin transcriptional responses. Journal of Cell Science 135:8.
Crossref
Anna-Lena Lemster, Elisabeth Sievers, Helen Pasternack, Pamela Lazar-Karsten, Niklas Klümper, Verena Sailer, Anne Offermann, Johannes Brägelmann, Sven Perner & Jutta Kirfel. (2022) Histone Demethylase KDM5C Drives Prostate Cancer Progression by Promoting EMT. Cancers 14:8, pages 1894.
Crossref
Julia Swoboda, Patrick Mittelsdorf, Yuan Chen, Ralf Weiskirchen, Johannes Stallhofer, Silke Schüle & Nikolaus Gassler. (2022) Intestinal Wnt in the transition from physiology to oncology. World Journal of Clinical Oncology 13:3, pages 168-185.
Crossref
Edward J. Perkins, E. Alice Woolard & Natàlia Garcia-Reyero. (2022) Integration of Adverse Outcome Pathways, Causal Networks and ‘Omics to Support Chemical Hazard Assessment. Frontiers in Toxicology 4.
Crossref
Aneliya Knauthe, Sonnhild Mittag, Laura Bloch, Kai Frederik Albring, Martin Schmidt, Oliver Werz & Otmar Huber. (2022) Hyperforin and Myrtucommulone Derivatives Act as Natural Modulators of Wnt/β-Catenin Signaling in HCT116 Colon Cancer Cells. International Journal of Molecular Sciences 23:6, pages 2984.
Crossref
Ana R. Moshkovsky & Marc W. Kirschner. (2022) The nonredundant nature of the Axin2 regulatory network in the canonical Wnt signaling pathway. Proceedings of the National Academy of Sciences 119:9.
Crossref
Jeffry Cesario, Sara Ha, Julie Kim, Niam Kataria & Juhee Jeong. (2022) Candidate positive targets of LHX6 and LHX8 transcription factors in the developing upper jaw. Gene Expression Patterns 43, pages 119227.
Crossref
Maryla Młynarczyk & Irena Kasacka. (2022) The role of the Wnt/β-catenin pathway and the functioning of the heart in arterial hypertension – A review. Advances in Medical Sciences 67:1, pages 87-94.
Crossref
Elsa Bourayou & Rachel Golub. (2022) Signaling Pathways Tuning Innate Lymphoid Cell Response to Hepatocellular Carcinoma. Frontiers in Immunology 13.
Crossref
Rokas Lukosevicius, Simonas Juzenas, Violeta Salteniene, Ugne Kulokiene, Justina Arstikyte, Georg Hemmrich-Stanisak, Andre Franke, Alexander Link, Paulius Ruzgys, Saulius Satkauskas, Henrikas Pauzas, Tadas Latkauskas, Gediminas Kiudelis, Francesc Balaguer, Juozas Kupcinskas & Jurgita Skieceviciene. (2022) miRNome Profiling and Functional Analysis Reveal Involvement of hsa-miR-1246 in Colon Adenoma-Carcinoma Transition by Targeting AXIN2 and CFTR. International Journal of Molecular Sciences 23:4, pages 2107.
Crossref
Cezanne Miete, Gonzalo P. Solis, Alexey Koval, Martina Brückner, Vladimir L. Katanaev, Jürgen Behrens & Dominic B. Bernkopf. (2022) Gαi2-induced conductin/axin2 condensates inhibit Wnt/β-catenin signaling and suppress cancer growth. Nature Communications 13:1.
Crossref
Elisa Pedone, Mario Failli, Gennaro Gambardella, Rossella De Cegli, Antonella La Regina, Diego di Bernardo & Lucia Marucci. (2022) β-catenin perturbations control differentiation programs in mouse embryonic stem cells. iScience 25:2, pages 103756.
Crossref
Austin Armstrong, Ashok Mandala, Milan Malhotra & Jaya P. Gnana-Prakasam. (2022) Canonical Wnt Signaling in the Pathology of Iron Overload-Induced Oxidative Stress and Age-Related Diseases. Oxidative Medicine and Cellular Longevity 2022, pages 1-13.
Crossref
Shion Orikasa, Nobuyuki Kawashima, Kento Tazawa, Kentaro Hashimoto, Keisuke Sunada-Nara, Sonoko Noda, Mayuko Fujii, Tetsu Akiyama & Takashi Okiji. (2022) Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9. Scientific Reports 12:1.
Crossref
Jenny A. Klein, Zhen Li, Sanjeev Rampam, Jack Cardini, Amara Ayoub, Patricia Shaw, Angela L. Rachubinski, Joaquin M. Espinosa, Ella Zeldich & Tarik F. Haydar. (2022) Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs With Trisomy 21. Frontiers in Cellular Neuroscience 15.
Crossref
Sarah S. McCarthy, Michele Karolak & Leif Oxburgh. (2022) Smad4 controls proliferation of interstitial cells in the neonatal kidney . Development 149:1.
Crossref
Alberto Bertozzi, Chi-Chung Wu, Stefan Hans, Michael Brand & Gilbert Weidinger. (2022) Wnt/β-catenin signaling acts cell-autonomously to promote cardiomyocyte regeneration in the zebrafish heart. Developmental Biology 481, pages 226-237.
Crossref
Yingying Han, Alvaro Villarreal-Ponce, Guadalupe GutierrezJr.Jr., Quy Nguyen, Peng Sun, Ting Wu, Benjamin Sui, Geert Berx, Thomas Brabletz, Kai Kessenbrock, Yi Arial Zeng, Kazuhide Watanabe & Xing Dai. (2022) Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1. Cell Reports 38:2, pages 110240.
Crossref
Ishita S. Hiremath, Arul Goel, Sudha Warrier, Alan Prem Kumar, Gautam Sethi & Manoj Garg. (2021) The multidimensional role of the Wnt/β‐catenin signaling pathway in human malignancies. Journal of Cellular Physiology 237:1, pages 199-238.
Crossref
Francisco Sir-Mendoza, Farith González-Martínez & Meisser Madera. (2021) Prevalence of KRAS, PIK3CA, BRAF and AXIN2 gene mutations in colorectal cancer and its relationship with dental agenesis: a systematic review. Revista de la Facultad de Medicina 71:1, pages e95595.
Crossref
Katharina F. Sonnen & Claudia Y. Janda. (2021) Signalling dynamics in embryonic development. Biochemical Journal 478:23, pages 4045-4070.
Crossref
Shaun Hurley, Conor Mohan, Philipp Suetterlin, Robert Ellingford, Kimberley L. H. Riegman, Jacob Ellegood, Angela Caruso, Caterina Michetti, Olivier Brock, Romy Evans, Fabrizio Rudari, Alessio Delogu, Maria Luisa Scattoni, Jason P. Lerch, Cathy Fernandes & M. Albert Basson. (2021) Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development. Molecular Autism 12:1.
Crossref
Haitao Gu, Zhiquan Xu, Jianbo Zhang, Yanbing Wei, Ling Cheng & Jijian Wang. (2021) circ_0038718 promotes colon cancer cell malignant progression via the miR-195-5p/Axin2 signaling axis and also effect Wnt/β-catenin signal pathway. BMC Genomics 22:1.
Crossref
Federico Ghiselli, Barbara Rossi, Martina Felici, Maria Parigi, Giovanni Tosi, Laura Fiorentini, Paola Massi, Andrea Piva & Ester Grilli. (2021) Isolation, culture, and characterization of chicken intestinal epithelial cells. BMC Molecular and Cell Biology 22:1.
Crossref
Mengqi Zhou, Hong Zhang, Heather Camhi, Figen Seymen, Mine Koruyucu, Yelda Kasimoglu, Jung-Wook Kim, Hera Kim-Berman, Ninna M. R. Yuson, Paul J. Benke, Yiqun Wu, Feng Wang, Yaqin Zhu, James P. Simmer & Jan C-C. Hu. (2021) Analyses of oligodontia phenotypes and genetic etiologies. International Journal of Oral Science 13:1.
Crossref
Hoang Dong Nguyen, Martine Bisson, Michelle Scott, Gilles Boire, Luigi Bouchard & Sophie Roux. (2021) miR profile in pagetic osteoclasts: from large-scale sequencing to gene expression study. Journal of Molecular Medicine 99:12, pages 1771-1781.
Crossref
Thomas NaertDieter TulkensTom Van NieuwenhuysenJoanna PrzybylSuzan DemuynckMatt van de RijnMushriq Al-JazraweBenjamin A. AlmanPaul J. CouckeKim De LeeneerChristian Vanhove, Savvas N. Savvides, David Creytens & Kris Vleminckx. (2021) CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping. Proceedings of the National Academy of Sciences 118:47.
Crossref
Soohyun P. Kim, Hao Da, Lei Wang, Makoto M. Taketo, Mei Wan & Ryan C. Riddle. (2021) Bone‐derived sclerostin and Wnt/β‐catenin signaling regulate PDGFRα + adipoprogenitor cell differentiation . The FASEB Journal 35:11.
Crossref
Benjamin M Vierra. (2021) Prophylactic subtotal colectomy in a patient with an AXIN2 mutation. Journal of Surgical Case Reports 2021:11.
Crossref
Tony Oosterveen, Pedro Garção, Emma Moles-Garcia, Clement Soleilhavoup, Marco Travaglio, Shahida Sheraz, Rosa Peltrini, Kieran Patrick, Valerie Labas, Lucie Combes-Soia, Ulrika Marklund, Peter Hohenstein & Lia Panman. (2021) Pluripotent stem cell derived dopaminergic subpopulations model the selective neuron degeneration in Parkinson’s disease. Stem Cell Reports 16:11, pages 2718-2735.
Crossref
Devesh Tewari, Sweta Bawari, Shikha Sharma, Lindsay K. DeLiberto & Anupam Bishayee. (2021) Targeting the crosstalk between canonical Wnt/β-catenin and inflammatory signaling cascades: A novel strategy for cancer prevention and therapy. Pharmacology & Therapeutics 227, pages 107876.
Crossref
Linlin Zhang, Min Sang, Ying Li, Yingying Li, Erfeng Yuan, Lijun Yang, Wenli Shi, Yangyang Yuan, Bo Yang, Peifeng Yang & Enwu Yuan. (2021) WNT3 hypomethylation counteracts low activity of the Wnt signaling pathway in the placenta of preeclampsia. Cellular and Molecular Life Sciences 78:21-22, pages 6995-7008.
Crossref
Priyanka Garg, Maura Strigini, Laura Peurière, Laurence Vico & Donata Iandolo. (2021) The Skeletal Cellular and Molecular Underpinning of the Murine Hindlimb Unloading Model. Frontiers in Physiology 12.
Crossref
Barbara Świerczek-Lasek, Damian Dudka, Damian Bauer, Tomasz Czajkowski, Katarzyna Ilach, Władysława Streminska, Agata Kominek, Katarzyna Piwocka, Maria A. Ciemerych & Karolina Archacka. (2021) Comparison of Differentiation Pattern and WNT/SHH Signaling in Pluripotent Stem Cells Cultured under Different Conditions. Cells 10:10, pages 2743.
Crossref
Lauren V. Albrecht, Nydia Tejeda-MuñozEdward M. De Robertis. (2021) Cell Biology of Canonical Wnt Signaling. Annual Review of Cell and Developmental Biology 37:1, pages 369-389.
Crossref
Venkata Thulabandu, Timothy Nehila, James W. Ferguson & Radhika P. Atit. (2021) Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development. Developmental Biology 478, pages 25-40.
Crossref
Rofia Boudria, Vanessa Laurienté, Antonin Oudar, Souleymane Harouna-Rachidi, Elisabetta Dondi, Christine Le Roy, Laura Gardano, Nadine Varin-Blank & Lionel Guittat. (2021) Regulatory interplay between Vav1, Syk and β-catenin occurs in lung cancer cells. Cellular Signalling 86, pages 110079.
Crossref
Xue Tan, Lingling Zhang, Tianqi Li, Jianmin Zhan, Kun Qiao, Haili Wu, Shenfei Sun, Meina Huang, Fangxi Zhang, Meixing Zhang, Changwei Li, Runsheng Li & Hongjie Pan. (2021) Lgr4 Regulates Oviductal Epithelial Secretion Through the WNT Signaling Pathway. Frontiers in Cell and Developmental Biology 9.
Crossref
Young Yi, Young Mi Woo, Kyu Ho Hwang, Hyun Sil Kim & Sang Hyeong Lee. (2021) Niclosamide and Pyrvinium Are Both Potential Therapeutics for Osteosarcoma, Inhibiting Wnt–Axin2–Snail Cascade. Cancers 13:18, pages 4630.
Crossref
Frederic Abou Azar & Gareth E. Lim. (2021) Metabolic Contributions of Wnt Signaling: More Than Controlling Flight. Frontiers in Cell and Developmental Biology 9.
Crossref
Aravinda-Bharathi Ramakrishnan, Lisheng Chen, Peter E Burby & Ken M Cadigan. (2021) Wnt target enhancer regulation by a CDX/TCF transcription factor collective and a novel DNA motif. Nucleic Acids Research 49:15, pages 8625-8641.
Crossref
Soyoung Kim, Gahyeon Song, Taebok Lee, Minseong Kim, Jeongrae Kim, Hyeryun Kwon, Jiyoung Kim, Wonyoung Jeong, Ukjin Lee, Chaebin Na, Sangwon Kang, Wantae Kim, Je Kyung Seong & Eek-hoon Jho. (2021) PARsylated transcription factor EB (TFEB) regulates the expression of a subset of Wnt target genes by forming a complex with β-catenin-TCF/LEF1. Cell Death & Differentiation 28:9, pages 2555-2570.
Crossref
Sina Mohammadi, Carolina Morell-Perez, Charles W. Wright, Thomas P. Wyche, Cory H. White, Theodore R. Sana & Linda A. Lieberman. (2021) Assessing donor-to-donor variability in human intestinal organoid cultures. Stem Cell Reports 16:9, pages 2364-2378.
Crossref
Shenglan Li, Jinyi Chen, Feng Chen, Ce Wang, Xiaodi Guo, Can Wang, Yaqiong Fan, Yali Wang, Yichen Peng & Wenbin Li. (2021) Liposomal honokiol promotes hair growth via activating Wnt3a/β-catenin signaling pathway and down regulating TGF-β1 in C57BL/6N mice. Biomedicine & Pharmacotherapy 141, pages 111793.
Crossref
Jan Willem Bek, Chen Shochat, Adelbert De Clercq, Hanna De Saffel, Annekatrien Boel, Juriaan Metz, Frans Rodenburg, David Karasik, Andy Willaert & Paul J Coucke. (2021) Lrp5 Mutant and Crispant Zebrafish Faithfully Model Human Osteoporosis, Establishing the Zebrafish as a Platform for CRISPR ‐Based Functional Screening of Osteoporosis Candidate Genes . Journal of Bone and Mineral Research 36:9, pages 1749-1764.
Crossref
Shefali Mehta, Swapnil Hingole & Varun Chaudhary. (2021) The Emerging Mechanisms of Wnt Secretion and Signaling in Development. Frontiers in Cell and Developmental Biology 9.
Crossref
Krishnakali Dasgupta, Jeffry M. Cesario, Sara Ha, Kesava Asam, Lindsay J. Deacon, Ana H. Song, Julie Kim, John Cobb, Jeong Kyo Yoon & Juhee Jeong. (2021) R-Spondin 3 Regulates Mammalian Dental and Craniofacial Development. Journal of Developmental Biology 9:3, pages 31.
Crossref
Katsutoshi Sato, Amol A. Padgaonkar, Stacey J. Baker, Stephen C. Cosenza, Olga Rechkoblit, D. R. C. Venkata Subbaiah, Josep Domingo-Domenech, Alison Bartkowski, Elisa R. Port, Aneel K. Aggarwal, M. V. Ramana Reddy, Hanna Y. Irie & E. Premkumar Reddy. (2021) Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease. Nature Communications 12:1.
Crossref
Ying Zhao, Kai Meng, Yutong Yan, Yuyang Miao, Xiaoe Zhao, Qiang Wei & Baohua Ma. (2021) Inhibition of cell proliferation and promotion of acinus-like structure formation from goat mammary epithelial cells via Wnt/β-catenin signaling. In Vitro Cellular & Developmental Biology - Animal 57:7, pages 676-684.
Crossref
Ki M. Mak & Da Wi Shin. (2020) Hepatic sinusoids versus central veins: Structures, markers, angiocrines, and roles in liver regeneration and homeostasis. The Anatomical Record 304:8, pages 1661-1691.
Crossref
Hiu Lee, Mingjing Meng, Yulong Liu, Tao Su & Hiu Kwan. (2021) Medicinal herbs and bioactive compounds overcome the drug resistance to epidermal growth factor receptor inhibitors in non‑small cell lung cancer (Review). Oncology Letters 22:3.
Crossref
Alice H. Reis & Sergei Y. Sokol. (2021) Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification. Scientific Reports 11:1.
Crossref
Lore Pottie, Wouter Van Gool, Michiel Vanhooydonck, Franz-Georg Hanisch, Geert Goeminne, Andreja Rajkovic, Paul Coucke, Patrick Sips & Bert Callewaert. (2021) Loss of zebrafish atp6v1e1b, encoding a subunit of vacuolar ATPase, recapitulates human ARCL type 2C syndrome and identifies multiple pathobiological signatures. PLOS Genetics 17:6, pages e1009603.
Crossref
Anushree Vijaykumar & Mina Mina. (2021) Lithium Chloride Exerts Differential Effects on Dentinogenesis and Osteogenesis in Primary Pulp Cultures. Frontiers in Dental Medicine 2.
Crossref
Marua Abu Risha, Asghar Ali, Puntita Siengdee, Nares Trakooljul, Fiete Haack, Dirk Dannenberger, Klaus Wimmers & Siriluck Ponsuksili. (2021) Wnt signaling related transcripts and their relationship to energy metabolism in C2C12 myoblasts under temperature stress. PeerJ 9, pages e11625.
Crossref
Nestor Kamdem, Yvette Roske, Dmytro Kovalskyy, Maxim O. Platonov, Oleksii Balinskyi, Annika Kreuchwig, Jörn Saupe, Liang Fang, Anne Diehl, Peter Schmieder, Gerd Krause, Jörg Rademann, Udo Heinemann, Walter Birchmeier & Hartmut Oschkinat. (2021) Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling. Magnetic Resonance 2:1, pages 355-374.
Crossref
Barbora Putnová, Iveta Putnová, Miša Škorič & Marcela Buchtová. (2021) The Expression of Selected Wnt Pathway Members (FZD6, AXIN2 and β-Catenin) in Canine Oral Squamous Cell Carcinoma and Acanthomatous Ameloblastoma. Animals 11:6, pages 1615.
Crossref
Di Deng, Xiaoqing Qian, Binjun Chen, Xiaoyu Yang, Yanmei Wang, Fanglu Chi, Yibo Huang, Yu Zhao & Dongdong Ren. (2021) Canonical Wnt Signaling Pathway on Polarity Formation of Utricle Hair Cells. Neural Plasticity 2021, pages 1-11.
Crossref
Karol Kaiser, Ahram Jang, Petra Kompanikova, Melody P. Lun, Jan Prochazka, Ondrej Machon, Neil Dani, Michaela Prochazkova, Benoit Laurent, Daniel Gyllborg, Renee van Amerongen, Ryann M. Fame, Suhasini Gupta, Feizhen Wu, Roger A. Barker, Ivana Bukova, Radislav Sedlacek, Zbynek Kozmik, Ernest Arenas, Maria K. Lehtinen & Vitezslav Bryja. (2021) MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development 148:10.
Crossref
James W. Foster, Rupin N. Parikh, Jiangxia Wang, Kraig S. Bower, Mario Matthaei, Shukti Chakravarti, Albert S. Jun, Charles G. Eberhart & Uri S. Soiberman. (2021) Transcriptomic and Immunohistochemical Analysis of Progressive Keratoconus Reveal Altered WNT10A in Epithelium and Bowman's Layer. Investigative Opthalmology & Visual Science 62:6, pages 16.
Crossref
Yue Wu, Xiaosi Jin, Yuhao Zhang, Jing Zheng & Rulai Yang. (2021) Genetic and epigenetic mechanisms in the development of congenital heart diseases. World Journal of Pediatric Surgery 4:2, pages e000196.
Crossref
Marlyn D. Laksitorini, Vinith Yathindranath, Wei Xiong, Fiona E. Parkinson, James A. Thliveris & Donald W. Miller. (2020) Impact of Wnt/β‐catenin signaling on ethanol‐induced changes in brain endothelial cell permeability. Journal of Neurochemistry 157:4, pages 1118-1137.
Crossref
Simon Söderholm & Claudio Cantù. (2020) The WNT/β‐catenin dependent transcription: A tissue‐specific business. WIREs Mechanisms of Disease 13:3.
Crossref
Marina Kaiser, Irina Wojahn, Carsten Rudat, Timo H. Lüdtke, Vincent M. Christoffels, Anne Moon, Andreas Kispert & Mark-Oliver Trowe. (2021) Regulation of otocyst patterning by Tbx2 and Tbx3 is required for inner ear morphogenesis in the mouse . Development 148:8.
Crossref
Arie C. van Vliet, Jinhui Lee, Marlijn van der Poel, Matthew R. J. Mason, Jasprina N. Noordermeer, Lee G. Fradkin, Martijn R. Tannemaat, Martijn J. A. Malessy, Joost Verhaagen & Fred De Winter. (2021) Coordinated changes in the expression of Wnt pathway genes following human and rat peripheral nerve injury. PLOS ONE 16:4, pages e0249748.
Crossref
Kevin G Mark & Michael Rape. (2021) Ubiquitin‐dependent regulation of transcription in development and disease. EMBO reports 22:4.
Crossref
Rediet Zewdu, Elnaz Mirzaei Mehrabad, Kelley Ingram, Pengshu Fang, Katherine L Gillis, Soledad A Camolotto, Grace Orstad, Alex Jones, Michelle C Mendoza, Benjamin T Spike & Eric L Snyder. (2021) An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. eLife 10.
Crossref
Junxiu Nong, Kexin Kang, Qiaoni Shi, Xuechen Zhu, Qinghua Tao & Ye-Guang Chen. (2021) Phase separation of Axin organizes the β-catenin destruction complex. Journal of Cell Biology 220:4.
Crossref
Fatemeh Kiaee, Majid Zaki-Dizaji, Nasim Hafezi, Amir Almasi-Hashiani, Haleh Hamedifar, Araz Sabzevari, Afshin Shirkani, Zeineb Zian, Farhad Jadidi-Niaragh, Fatemeh Aghamahdi, Mahdi Goudarzvand, Reza Yazdani, Hassan Abolhassani, Asghar Aghamohammadi & Gholamreza Azizi. (2021) Clinical, Immunologic and Molecular Spectrum of Patients with Immunodeficiency, Centromeric Instability, and Facial Anomalies (ICF) Syndrome: A Systematic Review. Endocrine, Metabolic & Immune Disorders - Drug Targets 21:4, pages 664-672.
Crossref
Andrea Toth, Barbara Zhao & William J. Zacharias. 2021. Lung Stem Cells in Development, Health and Disease. Lung Stem Cells in Development, Health and Disease 122 133 .
A. Vijaykumar, S.H. Root & M. Mina. (2020) Wnt/β-Catenin Signaling Promotes the Formation of Preodontoblasts In Vitro. Journal of Dental Research 100:4, pages 387-396.
Crossref
Ada Weinstock, Karishma Rahman, Or Yaacov, Hitoo Nishi, Prashanthi Menon, Cyrus A Nikain, Michela L Garabedian, Stephanie Pena, Naveed Akbar, Brian E Sansbury, Sean P Heffron, Jianhua Liu, Gregory Marecki, Dawn Fernandez, Emily J Brown, Kelly V Ruggles, Stephen A Ramsey, Chiara Giannarelli, Matthew Spite, Robin P Choudhury, P'ng Loke & Edward A Fisher. (2021) Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis. eLife 10.
Crossref
Xiaoli Lou, Yuchen Meng & Yanqiang Hou. (2021) A literature review on function and regulation mechanism of DKK4. Journal of Cellular and Molecular Medicine 25:6, pages 2786-2794.
Crossref
Twan J. J. de Winter & Roeland Nusse. (2021) Running Against the Wnt: How Wnt/β-Catenin Suppresses Adipogenesis. Frontiers in Cell and Developmental Biology 9.
Crossref
Karen Dunbar, Rebecca A Jones, Kevin Dingwell, Thomas J Macartney, James C Smith & Gopal P Sapkota. (2020) FAM83F regulates canonical Wnt signalling through an interaction with CK1α. Life Science Alliance 4:2, pages e202000805.
Crossref
Karen Dunbar, Thomas J Macartney & Gopal P Sapkota. (2020) IMiDs induce FAM83F degradation via an interaction with CK1α to attenuate Wnt signalling. Life Science Alliance 4:2, pages e202000804.
Crossref
Juanmei Gao, Yuan Liao, Mengsheng Qiu & Wanhua Shen. (2020) Wnt/β-Catenin Signaling in Neural Stem Cell Homeostasis and Neurological Diseases. The Neuroscientist 27:1, pages 58-72.
Crossref
Bai Dai, Ri‐Na Sha, Jian‐Long Yuan & Dong‐Jun Liu. (2021) Multiple potential roles of thymosin β4 in the growth and development of hair follicles. Journal of Cellular and Molecular Medicine 25:3, pages 1350-1358.
Crossref
Dennis R. Warner, Jeffrey B. Warner, Josiah E. Hardesty, Ying L. Song, Chi‐Yu Chen, Zoe Chen, Jing X. Kang, Craig J. McClain & Irina A. Kirpich. (2021) Beneficial effects of an endogenous enrichment in n3‐PUFAs on Wnt signaling are associated with attenuation of alcohol‐mediated liver disease in mice. The FASEB Journal 35:2.
Crossref
Hidekazu Naganuma, Koichiro Miike, Tomoko Ohmori, Shunsuke Tanigawa, Takumi Ichikawa, Mariko Yamane, Masatoshi Eto, Hitoshi Niwa, Akio Kobayashi & Ryuichi Nishinakamura. (2021) Molecular detection of maturation stages in the developing kidney. Developmental Biology 470, pages 62-73.
Crossref
Donald W. LittleIIIIII, Typhanie Dumontet, Christopher R. LaPensee & Gary D. Hammer. (2021) β-catenin in adrenal zonation and disease. Molecular and Cellular Endocrinology 522, pages 111120.
Crossref
Mizuki Nagata, Noriaki Ono & Wanida Ono. (2020) Unveiling diversity of stem cells in dental pulp and apical papilla using mouse genetic models: a literature review. Cell and Tissue Research 383:2, pages 603-616.
Crossref
Kumiko Yoshioka-Kobayashi & Ryoichiro Kageyama. (2020) Imaging and manipulating the segmentation clock. Cellular and Molecular Life Sciences 78:4, pages 1221-1231.
Crossref
Hongfei Ge, Chao Zhang, Yang Yang, Weixiang Chen, Jun Zhong, Xuanyu Fang, Xuheng Jiang, Liang Tan, Yongjie Zou, Rong Hu, Yujie Chen & Hua Feng. (2021) Ambroxol Upregulates Glucocerebrosidase Expression to Promote Neural Stem Cells Differentiation Into Neurons Through Wnt/β-Catenin Pathway After Ischemic Stroke. Frontiers in Molecular Neuroscience 13.
Crossref
Ozgun Ozalp, Ozge Cark, Yagmur Azbazdar, Betul Haykir, Gokhan Cucun, Ismail Kucukaylak, Gozde Alkan-Yesilyurt, Erdinc Sezgin & Gunes Ozhan. (2021) Nradd Acts as a Negative Feedback Regulator of Wnt/β-Catenin Signaling and Promotes Apoptosis. Biomolecules 11:1, pages 100.
Crossref
Jiaxue Hao, Xufen Dai, Juan Gao, Yuexuan Li, Zhaoling Hou, Zhongman Chang & Yuxin Wang. (2021) Curcumin suppresses colorectal tumorigenesis via the Wnt/β‑catenin signaling pathway by downregulating Axin2. Oncology Letters 21:3.
Crossref
Avijit Mallick & Bhagwati P. Gupta. (2021) AXIN-AMPK signaling: Implications for healthy aging. F1000Research 10, pages 1259.
Crossref
Turk Rhen, Zachary Even, Alaina Brenner, Alexandra Lodewyk, Debojyoti Das, Sunil Singh & Rebecca Simmons. (2021) Evolutionary Turnover in Wnt Gene Expression but Conservation of Wnt Signaling during Ovary Determination in a TSD Reptile. Sexual Development 15:1-3, pages 47-68.
Crossref
Jeroen M. Bugter, Nicola Fenderico & Madelon M. Maurice. (2020) Mutations and mechanisms of WNT pathway tumour suppressors in cancer. Nature Reviews Cancer 21:1, pages 5-21.
Crossref
Joep Sprangers, Irene C. Zaalberg & Madelon M. Maurice. (2020) Organoid-based modeling of intestinal development, regeneration, and repair. Cell Death & Differentiation 28:1, pages 95-107.
Crossref
Wanchun Zhu, Tianchi Tang, Shijun Yuan, Bowen Chang, Shiting Li & Ming Chen. (2021) Prediction of CTNNB1 Mutation Status in Pediatric Cystic Adamantinomatous Craniopharyngioma by Using Preoperative Magnetic Resonance Imaging Manifestation. Clinical Neurology and Neurosurgery 200, pages 106347.
Crossref
Anjali P. Patni, Joel P. Joseph, D. Macrin & Arikketh Devi. 2021. Stem Cells and Aging. Stem Cells and Aging 9 52 .
Francesca Gori & Roland Baron. 2021. Marcus and Feldman's Osteoporosis. Marcus and Feldman's Osteoporosis 257 279 .
Pooja R. Sonavane & Karl Willert. 2021. Pharmacology of the WNT Signaling System. Pharmacology of the WNT Signaling System 3 28 .
Saskia Madelon Ada de Man & Renée van Amerongen. 2021. Pharmacology of the WNT Signaling System. Pharmacology of the WNT Signaling System 137 173 .
Neerajana Datta, Shrabastee Chakraborty, Malini Basu & Mrinal K. Ghosh. (2020) Tumor Suppressors Having Oncogenic Functions: The Double Agents. Cells 10:1, pages 46.
Crossref
Kevin O. Rivera, Fabrizio Russo, Ryan M. Boileau, Ryan E. Tomlinson, Theodore Miclau, Ralph S. Marcucio, Tejal A. Desai & Chelsea S. Bahney. (2020) Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion. Scientific Reports 10:1.
Crossref
Yue Zhang, Fanhong Zeng, Xu Han, Jun Weng & Yi Gao. (2020) Lineage tracing: technology tool for exploring the development, regeneration, and disease of the digestive system. Stem Cell Research & Therapy 11:1.
Crossref
Luciana Petti, Giulia Rizzo, Federica Rubbino, Sudharshan Elangovan, Piergiuseppe Colombo, Silvia Restelli, Andrea Piontini, Vincenzo Arena, Michele Carvello, Barbara Romano, Tommaso Cavalleri, Achille Anselmo, Federica Ungaro, Silvia D’Alessio, Antonino Spinelli, Sanja Stifter, Fabio Grizzi, Alessandro Sgambato, Silvio Danese, Luigi Laghi, Alberto Malesci & Stefania Vetrano. (2020) Unveiling role of sphingosine-1-phosphate receptor 2 as a brake of epithelial stem cell proliferation and a tumor suppressor in colorectal cancer. Journal of Experimental & Clinical Cancer Research 39:1.
Crossref
Vanessa Dietinger, Cira R. García de Durango, Svenja Wiechmann, Sophie L. Boos, Marlies Michl, Jens Neumann, Heiko Hermeking, Bernhard Kuster & Peter Jung. (2020) Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer. Cell Communication and Signaling 18:1.
Crossref
Tomasz Radaszkiewicz & Vítězslav Bryja. (2020) Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells. Cell Communication and Signaling 18:1.
Crossref
Tanne van der Wal & Renée van Amerongen. (2020) Walking the tight wire between cell adhesion and WNT signalling: a balancing act for β-catenin. Open Biology 10:12.
Crossref
Siu Chiu Chan, Sachin S. Hajarnis, Sophia M. Vrba, Vishal Patel & Peter Igarashi. (2020) Hepatocyte nuclear factor 1β suppresses canonical Wnt signaling through transcriptional repression of lymphoid enhancer–binding factor 1. Journal of Biological Chemistry 295:51, pages 17560-17572.
Crossref
Annie Tong, Yuh-Lit Chow, Katie Xu, Rita Hardiman, Paul Schneider & Seong-Seng Tan. (2020) Transcriptome analysis of ankylosed primary molars with infraocclusion. International Journal of Oral Science 12:1.
Crossref
James C. Cavallo, Steffen Scholpp & Mark B. Flegg. (2020) Delay-driven oscillations via Axin2 feedback in the Wnt/ -catenin signalling pathway . Journal of Theoretical Biology 507, pages 110458.
Crossref
Kedchin Jearawuttanakul, Phattharachanok Khumkhrong, Kanoknetr Suksen, Somrudee Reabroi, Bamroong Munyoo, Patoomratana Tuchinda, Suparerk Borwornpinyo, Nittaya Boonmuen & Arthit Chairoungdua. (2020) Cleistanthin A induces apoptosis and suppresses motility of colorectal cancer cells. European Journal of Pharmacology 889, pages 173604.
Crossref
Sam O. Kleeman & Simon J. Leedham. (2020) Not All Wnt Activation Is Equal: Ligand-Dependent versus Ligand-Independent Wnt Activation in Colorectal Cancer. Cancers 12:11, pages 3355.
Crossref
Jan S. Tchorz. (2020) The Conundrum of the Pericentral Hepatic Niche: WNT/-Catenin Signaling, Metabolic Zonation, and Many Open Questions. Gene Expression 20:2, pages 119-124.
Crossref

Displaying 200 of 1274 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.