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Molecular and Cellular Biology Volume 14, 1994 - Issue 11
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Cell Growth and Development

The Ribosomal L5 Protein Is Associated with mdm-2 and mdm-2-p53 Complexes

Vincent Marechal1 Service de Microbiologie, Hôpital Rothschild, F-75571Paris 12, France
,
Brian Elenbaas2 Department of Molecular Biology, Princeton University, Princeton, New Jersey08544−1014
,
Jacques Piette3 Institut de Génétique Moléculaire de Montpellier—UMR 9942, Centre National de la Recherche Scientifique, F-34033Montpellier Cedex 1, France
,
Jean-Claude Nicolas1 Service de Microbiologie, Hôpital Rothschild, F-75571Paris 12, France
&
Arnold J. Levine2 Department of Molecular Biology, Princeton University, Princeton, New Jersey08544−1014
Pages 7414-7420 | Received 16 Jun 1994, Accepted 09 Aug 1994, Published online: 30 Mar 2023

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Neylen Del Toro, Ana Fernandez-Ruiz, Lian Mignacca, Paloma Kalegari, Marie-Camille Rowell, Sebastian Igelmann, Emmanuelle Saint-Germain, Mehdi Benfdil, Stéphane Lopes-Paciencia, Léa Brakier-Gingras, Véronique Bourdeau, Gerardo Ferbeyre & Frédéric Lessard. (2019) Ribosomal protein RPL22/eL22 regulates the cell cycle by acting as an inhibitor of the CDK4-cyclin D complex. Cell Cycle 18:6-7, pages 759-770.
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Franziska Wandrey, Christian Montellese, Krisztian Koos, Lukas Badertscher, Lukas Bammert, Atlanta G. Cook, Ivo Zemp, Peter Horvath & Ulrike Kutay. (2015) The NF45/NF90 Heterodimer Contributes to the Biogenesis of 60S Ribosomal Subunits and Influences Nucleolar Morphology. Molecular and Cellular Biology 35:20, pages 3491-3503.
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Allison James, Yubo Wang, Himanshu Raje, Raphyel Rosby & Patrick DiMario. (2014) Nucleolar stress with and without p53. Nucleus 5:5, pages 402-426.
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Takayoshi Yamauchi, Masaaki Nishiyama, Toshiro Moroishi, Kanae Yumimoto & Keiichi I. Nakayama. (2014) MDM2 Mediates Nonproteolytic Polyubiquitylation of the DEAD-Box RNA Helicase DDX24. Molecular and Cellular Biology 34:17, pages 3321-3340.
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Graeme Walker & Neil Box. (2008) Ribosomal stress, p53 activation and the tanning response. Expert Review of Dermatology 3:6, pages 649-656.
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Jason A Lehman, Jacob A Eitel, Christopher N Batuello & Lindsey D Mayo. (2008) Therapeutic considerations for Mdm2: not just a one trick pony. Expert Opinion on Drug Discovery 3:11, pages 1309-1321.
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Mikael S. Lindstroöm, Aiwen Jin, Chad Deisenroth, Gabrielle White Wolf & Yanping Zhang. (2007) Cancer-Associated Mutations in the MDM2 Zinc Finger Domain Disrupt Ribosomal Protein Interaction and Attenuate MDM2-Induced p53 Degradation. Molecular and Cellular Biology 27:3, pages 1056-1068.
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Linda Panić, Sanda Tamarut, Melanie Sticker-Jantscheff, Martina Barkić, Davor Solter, Miljana Uzelac, Kristina Grabušić & Siniša Volarević. (2006) Ribosomal Protein S6 Gene Haploinsufficiency Is Associated with Activation of a p53-Dependent Checkpoint during Gastrulation. Molecular and Cellular Biology 26:23, pages 8880-8891.
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Yue Yu, Leonard B. Maggi$suffix/text()$suffix/text(), Suzanne N. Brady, Anthony J. Apicelli, Mu-Shui Dai, Hua Lu & Jason D. Weber. (2006) Nucleophosmin Is Essential for Ribosomal Protein L5 Nuclear Export. Molecular and Cellular Biology 26:10, pages 3798-3809.
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Aiwen Jin, Koji Itahana, Kevin O'Keefe & Yanping Zhang. (2004) Inhibition of HDM2 and Activation of p53 by Ribosomal Protein L23. Molecular and Cellular Biology 24:17, pages 7669-7680.
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Mu-Shui Dai, Shelya X. Zeng, Yetao Jin, Xiao-Xin Sun, Larry David & Hua Lu. (2004) Ribosomal Protein L23 Activates p53 by Inhibiting MDM2 Function in Response to Ribosomal Perturbation but Not to Translation Inhibition. Molecular and Cellular Biology 24:17, pages 7654-7668.
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Julia I. Bárdos, Noan-Minh Chau & Margaret Ashcroft. (2004) Growth Factor-Mediated Induction of HDM2 Positively Regulates Hypoxia-Inducible Factor 1α Expression. Molecular and Cellular Biology 24:7, pages 2905-2914.
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Yanping Zhang, Gabrielle White Wolf, Krishna Bhat, Aiwen Jin, Theresa Allio, William A. Burkhart & Yue Xiong. (2003) Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway. Molecular and Cellular Biology 23:23, pages 8902-8912.
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Dimitri G. Pestov, Žaklina Strezoska & Lester F. Lau. (2001) Evidence of p53-Dependent Cross-Talk between Ribosome Biogenesis and the Cell Cycle: Effects of Nucleolar Protein Bop1 on G1/S Transition. Molecular and Cellular Biology 21:13, pages 4246-4255.
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Susan J. Miller, Tuangporn Suthiphongchai, Gerard P. Zambetti & Mark E. Ewen. (2000) p53 Binds Selectively to the 5′ Untranslated Region of cdk4, an RNA Element Necessary and Sufficient for Transforming Growth Factor β- and p53-Mediated Translational Inhibition of cdk4. Molecular and Cellular Biology 20:22, pages 8420-8431.
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Weiguo Zhai & Lucio Comai. (2000) Repression of RNA Polymerase I Transcription by the Tumor Suppressor p53. Molecular and Cellular Biology 20:16, pages 5930-5938.
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Jason D. Weber, Mei-Ling Kuo, Brian Bothner, Enrico L. DiGiammarino, Richard W. Kriwacki, Martine F. Roussel & Charles J. Sherr. (2000) Cooperative Signals Governing ARF-Mdm2 Interaction and Nucleolar Localization of the Complex. Molecular and Cellular Biology 20:7, pages 2517-2528.
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Öonagh Loughran & Nicholas B. La Thangue. (2000) Apoptotic and Growth-Promoting Activity of E2F Modulated by MDM2. Molecular and Cellular Biology 20:6, pages 2186-2197.
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Tamar Juven-Gershon, Ohad Shifman, Tamar Unger, Adi Elkeles, Ygal Haupt & Moshe Oren. (1998) The Mdm2 Oncoprotein Interacts with the Cell Fate Regulator Numb. Molecular and Cellular Biology 18:7, pages 3974-3982.
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Beatriz M. A. Fontoura, Cesar A. Atienza, Elena A. Sorokina, Takashi Morimoto & Robert B. Carroll. (1997) Cytoplasmic p53 Polypeptide Is Associated with Ribosomes. Molecular and Cellular Biology 17:6, pages 3146-3154.
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Jiandong Chen, Xiangwei Wu, Jiayuh Lin & Arnold J. Levine. (1996) mdm-2 Inhibits the G1 Arrest and Apoptosis Functions of the p53 Tumor Suppressor Protein. Molecular and Cellular Biology 16:5, pages 2445-2452.
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Takashi Watanabe, Atsushi Ichikawa, Hidehiko Saito & Tomomitsu Hotta. (1996) Overexpression of the MDM2 Oncogene in Leukemia and Lymphoma. Leukemia & Lymphoma 21:5-6, pages 391-397.
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Sharon Klein, Takashi Morimoto & Daniel B. Rifkin. (1996) Characterization of Fibroblast Growth Factor-2 Binding to Ribosomes. Growth Factors 13:3-4, pages 219-228.
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Articles from other publishers (10)

Gazmend Temaj, Rifat Hadziselimovic, Hilada Nefic & Nexhibe Nuhii. (2022) Ribosome biogenesis and ribosome therapy in cancer cells. Research Results in Pharmacology 8:4, pages 15-24.
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Asimina Zisi, Jiri Bartek & Mikael S. Lindström. (2022) Targeting Ribosome Biogenesis in Cancer: Lessons Learned and Way Forward. Cancers 14:9, pages 2126.
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Sladana BursaćMaja Cokarić BrdovčakMartin PfannkuchenInes OrsolićLior Golomb, Yan Zhu, Chen Katz, Lilyn Daftuar, Kristina GrabušićIva VukelićVedrana FilićMoshe Oren, Carol Prives & Siniša Volarević. (2012) Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress. Proceedings of the National Academy of Sciences 109:50, pages 20467-20472.
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Wuguo Chen & Dirk P. Dittmer. (2011) Ribosomal Protein S6 Interacts with the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus. Journal of Virology 85:18, pages 9495-9505.
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Abhik Saha, Masanao Murakami, Pankaj Kumar, Bharat Bajaj, Karen Sims & Erle S. Robertson. (2009) Epstein-Barr Virus Nuclear Antigen 3C Augments Mdm2-Mediated p53 Ubiquitination and Degradation by Deubiquitinating Mdm2. Journal of Virology 83:9, pages 4652-4669.
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Alyson W. MacInnes, Adam Amsterdam, Charles A. Whittaker, Nancy Hopkins & Jacqueline A. Lees. (2008) Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations. Proceedings of the National Academy of Sciences 105:30, pages 10408-10413.
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Weikang Tao & Arnold J. Levine. (1999) P19 ARF stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2 . Proceedings of the National Academy of Sciences 96:12, pages 6937-6941.
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Lihong Chen, Sudhir Agrawal, Wenqiang Zhou, Ruiwen Zhang & Jiandong Chen. (1998) Synergistic activation of p53 by inhibition of MDM2 expression and DNA damage . Proceedings of the National Academy of Sciences 95:1, pages 195-200.
Crossref
Yu Wu, Hua Huang, Zoe Miner & Molly Kulesz-Martin. (1997) Activities and response to DNA damage of latent and active sequence-specific DNA binding forms of mouse p53. Proceedings of the National Academy of Sciences 94:17, pages 8982-8987.
Crossref
D. Mark PritchardAlastair J. M. WatsonChristopher S. PottenAnn L. JackmanJohn A. Hickman. (1997) Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: Evidence for the involvement of RNA perturbation. Proceedings of the National Academy of Sciences 94:5, pages 1795-1799.
Crossref

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