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Original Article

Cost-utility analysis of deferasirox compared to standard therapy with desferrioxamine for patients requiring iron chelation therapy in the United Kingdom

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Pages 1609-1621 | Accepted 14 Mar 2008, Published online: 23 Apr 2008

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Evan W Davies, Samuel Llewellyn, Amélie Beaudet, Charlotte E Kosmas, Wendy Gin-Sing & Helen A Doll. (2018) Elicitation of health state utilities associated with the mode of administration of drugs acting on the prostacyclin pathway in pulmonary arterial hypertension. Patient Preference and Adherence 12, pages 1079-1088.
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Ali T Taher, John B Porter, Antonis Kattamis, Vip Viprakasit & M Domenica Cappellini. (2016) Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with nontransfusion-dependent thalassemia syndromes. Drug Design, Development and Therapy 10, pages 4073-4078.
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N.C. Desai & R.D. Senta. (2015) Simultaneous Rp-HPLC determination of salicylamide, salicylic acid and deferasirox in the bulk API dosages forms. Journal of Taibah University for Science 9:2, pages 245-251.
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Todd A Lee, Sarah von Riedemann & Fernando Tricta. (2014) Cost-utility of chelators in transfusion-dependent β-thalassemia major patients: a review of the pharmacoeconomic literature. Expert Review of Pharmacoeconomics & Outcomes Research 14:5, pages 651-660.
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K. Tolley, N. Oliver, E. Miranda, K. Migliaccio-Walle, D. Bozkaya & Q. Li. (2010) Cost effectiveness of deferasirox compared to desferrioxamine in the treatment of iron overload in lower-risk, transfusion-dependent myelodysplastic syndrome patients. Journal of Medical Economics 13:3, pages 559-570.
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Ali Taher & Maria Domenica Cappellini. (2009) Update on the use of deferasirox in the management of iron overload. Therapeutics and Clinical Risk Management 5, pages 857-868.
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Farhan Imran & Pradyumna Phatak. (2009) Pharmacoeconomic benefits of deferasirox in the management of iron overload syndromes. Expert Review of Pharmacoeconomics & Outcomes Research 9:4, pages 297-304.
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Louis S. Matza, L. Clark Paramore, Katie D. Stewart, Hayley Karn, Minesh Jobanputra & Andrew C. Dietz. (2019) Health state utilities associated with treatment for transfusion-dependent β-thalassemia. The European Journal of Health Economics 21:3, pages 397-407.
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Parisa Saiyarsarai, Elahe Khorasani, Hasti Photogeraphy, Mohsen Ghaffari Darab & Meysam Seyedifar. (2020) Cost-utility of new film-coated tablet formulation of deferasirox vs deferoxamine among major beta-thalassemia patients in Iran. Medicine 99:28, pages e20949.
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Monica Hadi, Paul Swinburn, Luba Nalysnyk, Alaa Hamed & Atul Mehta. (2018) A health state utility valuation study to assess the impact of treatment mode of administration in Gaucher disease. Orphanet Journal of Rare Diseases 13:1.
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Dijiong Wu, Xiaowen Wen, Wenbin Liu, Linlong Xu, Baodong Ye & Yuhong Zhou. (2017) A composite mouse model of aplastic anemia complicated with iron overload. Experimental and Therapeutic Medicine.
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Alessia Pepe, Giuseppe Rossi, Anthony Bentley, Maria Caterina Putti, Ludovica Frizziero, Domenico Giuseppe D’Ascola, Liana Cuccia, Anna Spasiano, Aldo Filosa, Vincenzo Caruso, Aishah Hanif & Antonella Meloni. (2017) Cost-Utility Analysis of Three Iron Chelators Used in Monotherapy for the Treatment of Chronic Iron Overload in β-Thalassaemia Major Patients: An Italian Perspective. Clinical Drug Investigation 37:5, pages 453-464.
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Guido Crisponi, Valeria Marina Nurchi & Maria Antonietta Zoroddu. (2014) Iron Chelating Agents for Iron Overload Diseases. Thalassemia Reports 4:2, pages 2046.
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Nick Adlard, Philip Kinghorn & Emma Frew. (2014) Is the UK NICE “Reference Case” Influencing the Practice of Pediatric Quality-Adjusted Life-Year Measurement within Economic Evaluations?. Value in Health 17:4, pages 454-461.
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Winfred C Wang & Kerry Dwan. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Anthony Bentley, Samantha Gillard, Michael Spino, John Connelly & Fernando Tricta. (2013) Cost–Utility Analysis of Deferiprone for the Treatment of β-Thalassaemia Patients with Chronic Iron Overload: A UK Perspective. PharmacoEconomics 31:9, pages 807-822.
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Ali Keshtkaran, Mehdi Javanbakht, Sedigheh Salavati, Atefeh Mashayekhi, Mehran Karimi & Bijan Nuri. (2013) Cost-utility analysis of oral deferasirox versus infusional deferoxamine in transfusion-dependent β-thalassemia patients. Transfusion 53:8, pages 1722-1729.
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Jonathan Karnon, Keith Tolley, Joao Vieira & David Chandiwana. (2012) Lifetime Cost-Utility Analyses of Deferasirox in Beta-Thalassaemia Patients with Chronic Iron Overload. Clinical Drug Investigation 32:12, pages 805-815.
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L. B. Jordan, F. Vekeman, A. Sengupta, M. Corral, A. Guo & M. S. Duh. (2012) Persistence and compliance of deferoxamine versus deferasirox in Medicaid patients with sickle-cell disease. Journal of Clinical Pharmacy and Therapeutics 37:2, pages 173-181.
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Nantasit Luangasanatip, Nathorn Chaiyakunapruk, Nilawan Upakdee & Peerapon Wong. (2011) Iron-Chelating Therapies in a Transfusion-Dependent Thalassaemia Population in Thailand. Clinical Drug Investigation 31:7, pages 493-505.
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Manuel Muñoz, José Antonio García-Erce & Ángel Francisco Remacha. (2011) Disorders of iron metabolism. Part II: iron deficiency and iron overload. Journal of Clinical Pathology 64:4, pages 287-296.
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Heather A. Leitch. (2011) Optimizing Therapy for Iron Overload in the Myelodysplastic Syndromes. Drugs 71:2, pages 155-177.
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R.H.B. Meyboom. 2011. A worldwide yearly survey of new data in adverse drug reactions. A worldwide yearly survey of new data in adverse drug reactions 465 478 .
Pattara Leelahavarong, Usa Chaikledkaew, Suradej Hongeng, Vijj Kasemsup, Yoel Lubell & Yot Teerawattananon. (2010) A cost-utility and budget impact analysis of allogeneic hematopoietic stem cell transplantation for severe thalassemic patients in Thailand. BMC Health Services Research 10:1.
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Aryeh Shander & Kathleen Sazama. (2010) Clinical consequences of iron overload from chronic red blood cell transfusions, its diagnosis, and its management by chelation therapy. Transfusion 50:5, pages 1144-1155.
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Jinhyun Kim & Younhee Kim. (2009) A Time-Cost Augmented Economic Evaluation of Oral Deferasirox versus Infusional Dereroxmine for Patients with Iron Overload in South Korea. Value in Health 12, pages S78-S81.
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David P. Steensma. (2009) Myelodysplasia paranoia: Iron as the new radon. Leukemia Research 33:9, pages 1158-1163.
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Federica PiloAnna Angela Di TucciLaura DessìEmanuele Angelucci. (2009) Management of Transfusional Chronic Iron Overload: Focus on Deferasirox. Clinical Medicine. Therapeutics 1, pages CMT.S1970.
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