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Bioscience, Biotechnology, and Biochemistry Volume 76, 2012 - Issue 3
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Original Articles

Introducing Site-Specific Glycosylation Using Protein Engineering Techniques Reduces the Immunogenicity of β-Lactoglobulin

Yoshiyuki TATSUMIDepartment of Applied Biological Science, Tokyo University of Agriculture and Technology
,
Yoshimasa SASAHARADepartment of Applied Biological Science, Tokyo University of Agriculture and Technology
,
Noriki KOHYAMADepartment of Applied Biological Science, Tokyo University of Agriculture and Technology
,
Satomi AYANODepartment of Applied Biological Science, Tokyo University of Agriculture and Technology
,
Michio ENDODepartment of Applied Biological Science, Tokyo University of Agriculture and Technology
,
Tadashi YOSHIDADepartment of Applied Biological Science, Tokyo University of Agriculture and Technology
,
Kiyoshi YAMADADepartment of Applied Biological Chemistry, The University of Tokyo
,
Mamoru TOTSUKADepartment of Applied Biological Chemistry, The University of Tokyo
&
Makoto HATTORIDepartment of Applied Biological Science, Tokyo University of Agriculture and Technology
 show all
Pages 478-485 | Received 11 Oct 2011, Accepted 24 Nov 2011, Published online: 22 May 2014

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Qun Zhou, Julie Jaworski, Yanfeng Zhou, Delphine Valente, Joanne Cotton, Denise Honey, Ekaterina Boudanova, Jochen Beninga, Ercole Rao, Ronnie Wei, Christine Mauriac, Clark Pan, Anna Park & Huawei Qiu. (2020) Engineered Fc-glycosylation switch to eliminate antibody effector function. mAbs 12:1.
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Seronei Chelulei Cheison & Ulrich Kulozik. (2017) Impact of the environmental conditions and substrate pre-treatment on whey protein hydrolysis: A review. Critical Reviews in Food Science and Nutrition 57:2, pages 418-453.
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Naoki Inada, Mai Hayashi, Tadashi Yoshida & Makoto Hattori. (2015) Functional improvements in β-lactoglobulin by conjugating with soybean soluble polysaccharide. Bioscience, Biotechnology, and Biochemistry 79:1, pages 97-102.
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Articles from other publishers (13)

Michio Endo, Tadashi Yoshida, Keisatoi Ishii, Taku Iwamoto, Mamoru Totsuka & Makoto Hattori. (2023) Site-specific glycosylation and single amino acid substitution dramatically reduced the immunogenicity of β-lactoglobulin. Bioscience, Biotechnology, and Biochemistry 87:4, pages 426-433.
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Agustina Gugliotta, María Jesús Leopold, Eduardo Mufarrege, Marina Etcheverrigaray, Ricardo Kratje, Natalia Ceaglio & Marcos Oggero. (2021) Pharmacokinetics Versus In Vitro Antiproliferative Potency to Design a Novel Hyperglycosylated hIFN-α2 Biobetter. Pharmaceutical Research 38:1, pages 37-50.
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Raquel Caminha Dantas, Ludmilla Freire Caetano, Ariany Lima Sousa Torres, Matheus Soares Alves, Emanuelly Thays Muniz Figueiredo Silva, Louhanna Pinheiro Rodrigues Teixeira, Daniel Câmara Teixeira, Renato de Azevedo Moreira, Marcela Helena Gambim Fonseca, Saul Gaudêncio Neto, Leonardo Tondello Martins, Gilvan Pessoa Furtado & Kaio Cesar Simiano Tavares. (2019) Expression of a recombinant bacterial l-asparaginase in human cells. BMC Research Notes 12:1.
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Mats Carlsson, Martin Braddock, Yuling Li, Jihong Wang, Weichen Xu, Nicholas White, Ayman Megally, Gillian Hunter & Gene Colice. (2019) Evaluation of Antibody Properties and Clinically Relevant Immunogenicity, Anaphylaxis, and Hypersensitivity Reactions in Two Phase III Trials of Tralokinumab in Severe, Uncontrolled Asthma. Drug Safety 42:6, pages 769-784.
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Praveen Praveen, Martina Kocan, Adam Valkovic, Ross Bathgate & Mohammed Akhter Hossain. (2019) Single chain peptide agonists of relaxin receptors. Molecular and Cellular Endocrinology 487, pages 34-39.
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Qun Zhou & Huawei Qiu. (2019) The Mechanistic Impact of N-Glycosylation on Stability, Pharmacokinetics, and Immunogenicity of Therapeutic Proteins. Journal of Pharmaceutical Sciences 108:4, pages 1366-1377.
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Hiroshi Iwamoto, Takeshi Matsubara, Tomoyuki Okamoto, Takuya Matsumoto, Mayu Yoshikawa & Yasuhiro Takeda. (2019) Ingestion of Casein Hydrolysate Induces Oral Tolerance and Suppresses Subsequent Epicutaneous Sensitization and Development of Anaphylaxis Reaction to Casein in Mice. International Archives of Allergy and Immunology 179:3, pages 221-230.
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Sarfaraz Niazi. 2015. Biosimilars and Interchangeable Biologics. Biosimilars and Interchangeable Biologics 23 66 .
Lili Xu, Yu Shen, Jin Hou, Bingyin Peng, Hongting Tang & Xiaoming Bao. (2014) Secretory pathway engineering enhances secretion of cellobiohydrolase I from Trichoderma reesei in Saccharomyces cerevisiae. Journal of Bioscience and Bioengineering 117:1, pages 45-52.
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L. Sawyer. 2013. Advanced Dairy Chemistry. Advanced Dairy Chemistry 211 259 .
Miranda M. C. van Beers & Muriel Bardor. (2012) Minimizing immunogenicity of biopharmaceuticals by controlling critical quality attributes of proteins. Biotechnology Journal 7:12, pages 1473-1484.
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Rachael J. Almond, Brian F. Flanagan, Ian Kimber & Rebecca J. Dearman. (2012) Influence of protein expression system on elicitation of IgE antibody responses: Experience with lactoferrin. Toxicology 301:1-3, pages 50-57.
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Darja Kanduc. (2012) Homology, similarity, and identity in peptide epitope immunodefinition. Journal of Peptide Science 18:8, pages 487-494.
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