1,078
Views
86
CrossRef citations to date
0
Altmetric
Reviews

Anti-chemokine small molecule drugs: a promising future?

, &
Pages 345-355 | Published online: 29 Jan 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Tej Pratap Singh, Chang Hoon Lee & Joshua M Farber. (2013) Chemokine receptors in psoriasis. Expert Opinion on Therapeutic Targets 17:12, pages 1405-1422.
Read now
Percy H Carter. (2013) Progress in the discovery of CC chemokine receptor 2 antagonists, 2009 – 2012. Expert Opinion on Therapeutic Patents 23:5, pages 549-568.
Read now
Marie-Thérèse Labro. (2012) Immunomodulatory effects of antimicrobial agents. Part I: antibacterial and antiviral agents. Expert Review of Anti-infective Therapy 10:3, pages 319-340.
Read now
Hacer Sahin, Marie-Luise Berres & Hermann E Wasmuth. (2011) Therapeutic potential of chemokine receptor antagonists for liver disease. Expert Review of Clinical Pharmacology 4:4, pages 503-513.
Read now
Wan-Fai Ng & Simon J Bowman. (2011) Biological therapies in primary Sjögren's syndrome. Expert Opinion on Biological Therapy 11:7, pages 921-936.
Read now
Aadilah Omar, Katarina Jovanovic, Bianca Da Costa Dias, Danielle Gonsalves, Kiashanee Moodley, Robert Caveney, Vusi Mbazima & Stefan FT Weiss. (2011) Patented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptor. Expert Opinion on Therapeutic Patents 21:1, pages 35-53.
Read now
Catherine J. Hutchings, Markus Koglin & Fiona H. Marshall. (2010) Therapeutic antibodies directed at G protein-coupled receptors. mAbs 2:6, pages 594-606.
Read now
Morgan O'Hayre, Catherina L Salanga, Tracy M Handel & Damon J Hamel. (2010) Emerging concepts and approaches for chemokine-receptor drug discovery. Expert Opinion on Drug Discovery 5:11, pages 1109-1122.
Read now
Michael N Hedrick, Anke S Lonsdorf, Sam T Hwang & Joshua M Farber. (2010) CCR6 as a possible therapeutic target in psoriasis. Expert Opinion on Therapeutic Targets 14:9, pages 911-922.
Read now

Articles from other publishers (77)

Isabel Hamshaw, Marco M.D. Cominetti, Wing-Yee Lai, Mark Searcey & Anja Mueller. (2023) The development of potent, competitive CXCR4 antagonists for the prevention of cancer metastasis. Biochemical Pharmacology 218, pages 115921.
Crossref
Giuseppe Bardi. (2022) Chemokines and nanomaterials: interaction for useful immune-applications. Exploration of Immunology, pages 637-647.
Crossref
Marios K Georgakis, Jürgen Bernhagen, Laura H Heitman, Christian Weber & Martin Dichgans. (2022) Targeting the CCL2–CCR2 axis for atheroprotection. European Heart Journal 43:19, pages 1799-1808.
Crossref
S. Hopkin, J.M. Lord & M. Chimen. (2021) Dysregulation of leukocyte trafficking in ageing: Causal factors and possible corrective therapies. Pharmacological Research 163, pages 105323.
Crossref
Yoon Hyeun Oum, Steven A. Kell, Younghyoun Yoon, Zhongxing Liang, Pieter Burger & Hyunsuk Shim. (2020) Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design. European Journal of Medicinal Chemistry 201, pages 112479.
Crossref
Jason Johansen-Leete, Toby Passioura, Simon R. Foster, Ram Prasad Bhusal, Daniel J. Ford, Minglong Liu, Seino A. K. Jongkees, Hiroaki Suga, Martin J. Stone & Richard J. Payne. (2020) Discovery of Potent Cyclic Sulfopeptide Chemokine Inhibitors via Reprogrammed Genetic Code mRNA Display. Journal of the American Chemical Society 142:20, pages 9141-9146.
Crossref
T. Gerlza, C. Trojacher, D. Jeremic, E. Krieger, T. Adage & A. Kungl. (2020) PEGylation of a glycosaminoglycan-binding, dominant-negative CXCL8 mutant retains bioactivity in vitro and in vivo. Cytokine 127, pages 154942.
Crossref
Katia Urso, Andrés Fernández, Patricia Velasco, Javier Cotrina, Belén de Andrés, Pilar Sánchez-Gómez, Aurelio Hernández-Laín, Sonsoles Hortelano, Juan Miguel Redondo & Eva Cano. (2019) NFATc3 controls tumour growth by regulating proliferation and migration of human astroglioma cells. Scientific Reports 9:1.
Crossref
Sejal Saglani, Clare M. Lloyd & Andrew Bush. 2019. Kendig's Disorders of the Respiratory Tract in Children. Kendig's Disorders of the Respiratory Tract in Children 101 119.e4 .
Anneleen Van Hout, Alex Klarenbeek, Vladimir Bobkov, Jordi Doijen, Marta Arimont, Chunxia Zhao, Raimond Heukers, Rebecca Rimkunas, Chris de Graaf, Theo Verrips, Bas van der Woning, Hans de Haard, Joseph B. Rucker, Kurt Vermeire, Tracy Handel, Tom Van Loy, Martine J. Smit & Dominique Schols. (2018) CXCR4-targeting nanobodies differentially inhibit CXCR4 function and HIV entry. Biochemical Pharmacology 158, pages 402-412.
Crossref
Vincent Vanheule, Helena Crijns, Fariba Poosti, Pieter Ruytinx, Nele Berghmans, Tanja Gerlza, Isabelle Ronsse, Noëmie Pörtner, Patrick Matthys, Andreas J. Kungl, Ghislain Opdenakker, Sofie Struyf & Paul Proost. (2018) Anti-inflammatory effects of the GAG-binding CXCL9(74-103) peptide in dinitrofluorobenzene-induced contact hypersensitivity in mice. Clinical & Experimental Allergy 48:10, pages 1333-1344.
Crossref
Borja Mora-Peris, George Bouliotis, Kulasegaram Ranjababu, Amanda Clarke, Frank A. Post, Mark Nelson, Laura Burgess, Juan Tiraboschi, Saye Khoo, Steve Taylor, Deborah Ashby & Alan Winston. (2018) Changes in cerebral function parameters with maraviroc-intensified antiretroviral therapy in treatment naive HIV-positive individuals. AIDS 32:8, pages 1007-1015.
Crossref
Jing Chen, Bert Ribeiro, Han Li, Larnie Myer, Peter Chase, Neha Surti, Jonathan Lippy, Litao Zhang & Mary Ellen Cvijic. (2018) Leveraging the IncuCyte Technology for Higher-Throughput and Automated Chemotaxis Assays for Target Validation and Compound Characterization. SLAS Discovery 23:2, pages 122-131.
Crossref
Elodie Martin & Cécile Delarasse. (2018) Complex role of chemokine mediators in animal models of Alzheimer's Disease. Biomedical Journal 41:1, pages 34-40.
Crossref
So Ri Kim. 2018. Severe Asthma. Severe Asthma 99 122 .
Katja Škrlec, Anja Pucer Janež, Boris Rogelj, Borut Štrukelj & Aleš Berlec. (2017) Evasin‐displaying lactic acid bacteria bind different chemokines and neutralize CXCL 8 production in Caco‐2 cells . Microbial Biotechnology 10:6, pages 1732-1743.
Crossref
Shathiswaran N. Andy, Chim Kei Chan & Habsah Abdul Kadir. (2017) Deoxyelephantopin from Elephantopus scaber modulates neuroinflammatory response through MAPKs and PI3K/Akt-dependent NF-κB signaling pathways in LPS-stimulated BV-2 microglial cells. Journal of Functional Foods 38, pages 221-231.
Crossref
Michelle Miller & Kevin Mayo. (2017) Chemokines from a Structural Perspective. International Journal of Molecular Sciences 18:10, pages 2088.
Crossref
Irina KufarevaMartin GustavssonYi ZhengBryan S. StephensTracy M. Handel. (2017) What Do Structures Tell Us About Chemokine Receptor Function and Antagonism?. Annual Review of Biophysics 46:1, pages 175-198.
Crossref
Brooke I. Polk & Lanny J. Rosenwasser. (2017) Biological Therapies of Immunologic Diseases. Immunology and Allergy Clinics of North America 37:2, pages 247-259.
Crossref
B. C. Bhavya & Madathilkovilakath Haridas. 2017. Bioresources and Bioprocess in Biotechnology. Bioresources and Bioprocess in Biotechnology 235 268 .
George A. Parker & Tracey L. Papenfuss. 2017. Immunopathology in Toxicology and Drug Development. Immunopathology in Toxicology and Drug Development 1 93 .
Stefanie Karlshøj, Roxana Maria Amarandi, Olav Larsen, Viktorija Daugvilaite, Anne Steen, Matjaž Brvar, Aurel Pui, Thomas Michael Frimurer, Trond Ulven & Mette Marie Rosenkilde. (2016) Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5). Journal of Biological Chemistry 291:52, pages 26860-26874.
Crossref
Kohei Murakami, Shingo Maeda, Tomohiro Yonezawa & Naoaki Matsuki. (2016) CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis. Veterinary Immunology and Immunopathology 182, pages 52-58.
Crossref
Bhaumik A. Pandya, Christian Baber, Audrey Chan, Brian Chamberlain, Haoqun Chandonnet, Jennifer Goss, Timothy Hopper, Blaise Lippa, Katherine Poutsiaka, Jan Romero, Sabrina Stucka, Mustafa Varoglu, Jing Zhang & Xin Zhang. (2016) Discovery of indole inhibitors of chemokine receptor 9 (CCR9). Bioorganic & Medicinal Chemistry Letters 26:14, pages 3322-3325.
Crossref
Annette K. Brenner, Håkon Reikvam & Øystein Bruserud. (2016) A Subset of Patients with Acute Myeloid Leukemia Has Leukemia Cells Characterized by Chemokine Responsiveness and Altered Expression of Transcriptional as well as Angiogenic Regulators. Frontiers in Immunology 7.
Crossref
S. Barret Kalindjian, Sanjay V. Kadnur, Christopher A. Hewson, Chandregowda Venkateshappa, Suresh Juluri, Rajendra Kristam, Bheemashankar Kulkarni, Zainuddin Mohammed, Rohit Saxena, Vellarkad N. Viswanadhan, Jayashree Aiyar & Donna McVey. (2016) A New Series of Orally Bioavailable Chemokine Receptor 9 (CCR9) Antagonists; Possible Agents for the Treatment of Inflammatory Bowel Disease. Journal of Medicinal Chemistry 59:7, pages 3098-3111.
Crossref
Valérie Bégin-Lavallée, Élora Midavaine, Marc-André Dansereau, Pascal Tétreault, Jean-Michel Longpré, Ashley M Jacobi, Scott D Rose, Mark A Behlke, Nicolas Beaudet & Philippe Sarret. (2016) Functional inhibition of chemokine receptor CCR2 by dicer-substrate-siRNA prevents pain development. Molecular Pain 12, pages 174480691665396.
Crossref
Raymond H. de Wit, Sabrina M. de Munnik, Rob Leurs, Henry F. Vischer & Martine J. Smit. 2016. Chemokines. Chemokines 457 515 .
Roxana-Maria Amarandi, Gertrud Malene Hjortø, Mette Marie Rosenkilde & Stefanie Karlshøj. 2016. Chemokines. Chemokines 155 186 .
Chie Yoshiura, Takumi Ueda, Yutaka Kofuku, Masahiko Matsumoto, Junya Okude, Keita Kondo, Yutaro Shiraishi & Ichio Shimada. (2015) Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments. Journal of Biomolecular NMR 63:4, pages 333-340.
Crossref
Bryan D. Cox, Anil K. Mehta, John O. DiRaddo, Dennis C. Liotta, Lawrence J. Wilson & James P. Snyder. (2015) Structural analysis of CXCR4 – Antagonist interactions using saturation-transfer double-difference NMR. Biochemical and Biophysical Research Communications 466:1, pages 28-32.
Crossref
Daniel Kaemmerer, Christiane Reimann, Elisa Specht, Ralph M. Wirtz, Manal Sayeg, Richard P. Baum, Stefan Schulz & Amelie Lupp. (2014) Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms. Oncotarget 6:5, pages 3346-3358.
Crossref
Roberto Solari, James E. Pease & Malcolm Begg. (2015) “Chemokine receptors as therapeutic targets: Why aren’t there more drugs?”. European Journal of Pharmacology 746, pages 363-367.
Crossref
Manuela Calin, Daniela Stan, Martin Schlesinger, Viorel Simion, Mariana Deleanu, Cristina Ana Constantinescu, Ana-Maria Gan, Monica Madalina Pirvulescu, Elena Butoi, Ileana Manduteanu, Marian Bota, Marius Enachescu, Lubor Borsig, Gerd Bendas & Maya Simionescu. (2015) VCAM-1 directed target-sensitive liposomes carrying CCR2 antagonists bind to activated endothelium and reduce adhesion and transmigration of monocytes. European Journal of Pharmaceutics and Biopharmaceutics 89, pages 18-29.
Crossref
Alma ZerneckeChristian Weber. (2014) Chemokines in Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology 34:4, pages 742-750.
Crossref
Simon P FrickerMarkus Metz. (2014) Chemokine receptor modeling: an interdisciplinary approach to drug design. Future Medicinal Chemistry 6:1, pages 91-114.
Crossref
M. Møller, H. B. Søndergaard, N. Koch-Henriksen, P. S. Sorensen, F. Sellebjerg & A. B. Oturai. (2014) The chemokine receptor CCR5 Δ32 allele in natalizumab-treated multiple sclerosis . Acta Neurologica Scandinavica 129:1, pages 27-31.
Crossref
Shambhunath Bose & Jungsook Cho. (2013) Role of chemokine CCL2 and its receptor CCR2 in neurodegenerative diseases. Archives of Pharmacal Research 36:9, pages 1039-1050.
Crossref
Niklas Muenchmeier, Sophia Boecker, Lorenz Bankel, Laura Hinz, Nicole Rieth, Constantin Lapa, Anna N. Mendler, Elfriede Noessner, Ralph Mocikat & Peter J. Nelson. (2013) A Novel CXCL10-Based GPI-Anchored Fusion Protein as Adjuvant in NK-Based Tumor Therapy. PLoS ONE 8:8, pages e72749.
Crossref
Roberto Solari. (2013) Another chemokine target bites the dust?. Thorax 68:6, pages 501-503.
Crossref
Michael A. Kron, Ahmed Metwali, Sanja Vodanovic-Jankovic & David Elliott. (2013) Nematode Asparaginyl-tRNA Synthetase Resolves Intestinal Inflammation in Mice with T-Cell Transfer Colitis. Clinical and Vaccine Immunology 20:2, pages 276-281.
Crossref
Leah A. Mitchell, Ryan J. Hansen, Adam J. Beaupre, Daniel L. Gustafson & Steven W. Dow. (2013) Optimized dosing of a CCR2 antagonist for amplification of vaccine immunity. International Immunopharmacology 15:2, pages 357-363.
Crossref
Bryan Stephens & Tracy M. Handel. 2013. Oligomerization and Allosteric Modulation in G-Protein Coupled Receptors. Oligomerization and Allosteric Modulation in G-Protein Coupled Receptors 375 420 .
Martin U. Trinker & Andreas J. Kungl. (2012) Targeting chemokine–glycan interactions: the CellJammer® technology platform. Drug Discovery Today: Technologies 9:4, pages e253-e259.
Crossref
Maikel Wijtmans, Danny J. Scholten, Iwan J.P. de Esch, Martine J. Smit & Rob Leurs. (2012) Therapeutic targeting of chemokine receptors by small molecules. Drug Discovery Today: Technologies 9:4, pages e229-e236.
Crossref
Stefanie Thiele, Mikkel Malmgaard-Clausen, Jens Engel-Andreasen, Anne Steen, Pia C. Rummel, Mads C. Nielsen, David E. Gloriam, Thomas M. Frimurer, Trond Ulven & Mette M. Rosenkilde. (2012) Modulation in Selectivity and Allosteric Properties of Small-Molecule Ligands for CC-Chemokine Receptors. Journal of Medicinal Chemistry 55:18, pages 8164-8177.
Crossref
Simon Bowman & Francesca Barone. (2012) Biologic treatments in Sjögren's syndrome. La Presse Médicale 41:9, pages e495-e509.
Crossref
Dong Seok KimWei ZhangScott E. MillmanByung Joon Hwang, Seok Joo KwonCarol ClaybergerMichele Pagano & Alan M. Krensky. (2012) Fbw7γ-mediated degradation of KLF13 prevents RANTES expression in resting human but not murine T lymphocytes. Blood 120:8, pages 1658-1667.
Crossref
Carmen Gómez-Guerrero, Beñat Mallavia & Jesus Egido. (2012) Targeting Inflammation in Cardiovascular Diseases. Still a Neglected field?. Cardiovascular Therapeutics 30:4, pages e189-e197.
Crossref
Peter J. Nelson & Mauro M. Teixeira. (2012) Dissection of inflammatory processes using chemokine biology: Lessons from clinical models. Immunology Letters 145:1-2, pages 55-61.
Crossref
Marcello Allegretti, Maria Candida Cesta, Alexandre Garin & Amanda E.I. Proudfoot. (2012) Current status of chemokine receptor inhibitors in development. Immunology Letters 145:1-2, pages 68-78.
Crossref
Anne Jaerve & Hans Werner Müller. (2012) Chemokines in CNS injury and repair. Cell and Tissue Research 349:1, pages 229-248.
Crossref
Graeme O'Boyle. (2012) The yin and yang of chemokine receptor activation. British Journal of Pharmacology 166:3, pages 895-897.
Crossref
Annette Gilchrist. (2012) Are we just learning the scales on the chemokine receptor pianos?. Future Medicinal Chemistry 4:7, pages 825-827.
Crossref
Albert Zlotnik & Osamu Yoshie. (2012) The Chemokine Superfamily Revisited. Immunity 36:5, pages 705-716.
Crossref
Graeme O'Boyle, Christopher R. J. Fox, Hannah R. Walden, Joseph D. P. Willet, Emily R. Mavin, Dominic W. Hine, Jeremy M. Palmer, Catriona E. Barker, Christopher A. Lamb, Simi Ali & John A. Kirby. (2012) Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation. Proceedings of the National Academy of Sciences 109:12, pages 4598-4603.
Crossref
DJ Scholten, M Canals, D Maussang, L Roumen, MJ Smit, M Wijtmans, C de Graaf, HF Vischer & R Leurs. (2012) Pharmacological modulation of chemokine receptor function. British Journal of Pharmacology 165:6, pages 1617-1643.
Crossref
Ebrahim Haroon, Charles L Raison & Andrew H Miller. (2011) Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior. Neuropsychopharmacology 37:1, pages 137-162.
Crossref
Peter J. Barnes. (2012) Severe asthma: Advances in current management and future therapy. Journal of Allergy and Clinical Immunology 129:1, pages 48-59.
Crossref
Peter J. Barnes & Andrew Bush. 2012. Kendig & Chernickâs Disorders of the Respiratory Tract in Children. Kendig & Chernickâs Disorders of the Respiratory Tract in Children 75 88 .
Klaus Dembowsky, Barbara Romagnoli, Johann Zimmermann, Eric Chevalier, Christian Ludin & Daniel Obrecht. 2012. Novel Developments in Stem Cell Mobilization. Novel Developments in Stem Cell Mobilization 303 332 .
Elisabeth Ersvær, Guro Kristin Melve & Øystein Bruserud. (2011) Future perspectives: should Th17 cells be considered as a possible therapeutic target in acute myeloid leukemia patients receiving allogeneic stem cell transplantation?. Cancer Immunology, Immunotherapy 60:12, pages 1669-1681.
Crossref
Anamarija Čavčić, Goran Tešović, Lana Gorenec, Ivana Grgić, Branka Benić & Snježana Židovec Lepej. (2011) Concentration gradient of CXCL10 and CXCL11 between the cerebrospinal fluid and plasma in children with enteroviral aseptic meningitis. European Journal of Paediatric Neurology 15:6, pages 502-507.
Crossref
Gurdip Bhalay, Birgit Albrecht, Mohammed Akhlaq, Urs Baettig, David Beer, Zarin Brown, Steven Charlton, Andrew Dunstan, Michelle Bradley, Peter Gedeck, Angela Glen, Trevor Howe, Thomas Keller, Juliet Leighton-Davies, Alice Li, Clive McCarthy, Cecile Mocquet, Charles Owen, Paul Nicklin & Elizabeth Rosethorne. (2011) Design and synthesis of a library of chemokine antagonists. Bioorganic & Medicinal Chemistry Letters 21:21, pages 6249-6252.
Crossref
S Christen, M Holdener, C Beerli, G Thoma, M Bayer, J M Pfeilschifter, E Hintermann, H-G Zerwes & U Christen. (2011) Small molecule CXCR3 antagonist NIBR2130 has only a limited impact on type 1 diabetes in a virus-induced mouse model. Clinical and Experimental Immunology 165:3, pages 318-328.
Crossref
Carlo Selmi. (2011) Novel Challenges for the Allergist. Clinical Reviews in Allergy & Immunology 41:1, pages 1-3.
Crossref
Susanne Kramer, Peter Buontempo, Sony Agrawal & Robert Ralston. (2011) Imaging-Based Assay for Identification and Characterization of Inhibitors of CXCR4-Tropic HIV-1 Envelope-Dependent Cell-Cell Fusion. SLAS Discovery 16:6, pages 668-675.
Crossref
Thomas J. Schall & Amanda E. I. Proudfoot. (2011) Overcoming hurdles in developing successful drugs targeting chemokine receptors. Nature Reviews Immunology 11:5, pages 355-363.
Crossref
D J Dairaghi, P Zhang, Y Wang, L C Seitz, D A Johnson, S Miao, L S Ertl, Y Zeng, J P Powers, A M Pennell, P Bekker, T J Schall & J C Jaen. (2011) Pharmacokinetic and Pharmacodynamic Evaluation of the Novel CCR1 Antagonist CCX354 in Healthy Human Subjects: Implications for Selection of Clinical Dose. Clinical Pharmacology & Therapeutics 89:5, pages 726-734.
Crossref
Roberto Würth, Federica Barbieri, Adriana Bajetto, Alessandra Pattarozzi, Monica Gatti, Carola Porcile, Gianluigi Zona, Jean-Louis Ravetti, Renato Spaziante & Tullio Florio. (2011) Expression of CXCR7 chemokine receptor in human meningioma cells and in intratumoral microvasculature. Journal of Neuroimmunology 234:1-2, pages 115-123.
Crossref
David Kremer, Orhan Aktas, Hans‐Peter Hartung & Patrick Küry. (2011) The complex world of oligodendroglial differentiation inhibitors. Annals of Neurology 69:4, pages 602-618.
Crossref
Anneleen Mortier, Mieke Gouwy, Jo Van Damme & Paul Proost. (2011) Effect of posttranslational processing on the in vitro and in vivo activity of chemokines. Experimental Cell Research 317:5, pages 642-654.
Crossref
Clement Wesley Gnanadurai, Ivona Pandrea, Nicholas F. Parrish, Matthias H. Kraus, Gerald H. Learn, Maria G. Salazar, Ulrike Sauermann, Katharina Töpfer, Rajeev Gautam, Jan Münch, Christiane Stahl-Hennig, Christian Apetrei, Beatrice H. Hahn & Frank Kirchhoff. (2010) Genetic Identity and Biological Phenotype of a Transmitted/Founder Virus Representative of Nonpathogenic Simian Immunodeficiency Virus Infection in African Green Monkeys. Journal of Virology 84:23, pages 12245-12254.
Crossref
Hacer Sahin, Christian Trautwein & Hermann E. Wasmuth. (2010) Functional role of chemokines in liver disease models. Nature Reviews Gastroenterology & Hepatology 7:12, pages 682-690.
Crossref
Peter J. Barnes. (2010) New therapies for asthma: is there any progress?. Trends in Pharmacological Sciences 31:7, pages 335-343.
Crossref
Charles A. Dinarello. (2010) Anti-inflammatory Agents: Present and Future. Cell 140:6, pages 935-950.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.