Citations (74)
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Jekaterīna Ivanova, Morteza Abdoli, Alessio Nocentini, Raivis Žalubovskis & Claudiu T. Supuran. (2023) Derivatives of 4-methyl-1,2,3-benzoxathiazine 2,2-dioxide as selective inhibitors of human carbonic anhydrases IX and XII over the cytosolic isoforms I and II. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Jekaterina Ivanova, Morteza Abdoli, Alessio Nocentini, Raivis Žalubovskis & Claudiu T. Supuran. (2023) 1,2,3-Benzoxathiazine-2,2-dioxides – effective inhibitors of human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1, pages 225-238.
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Claudiu T. Supuran. (2022) Anti-obesity carbonic anhydrase inhibitors: challenges and opportunities. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2478-2488.
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Alessio Nocentini, Claudiu T. Supuran & Clemente Capasso. (2021) An overview on the recently discovered iota-carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 1988-1995.
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Claudiu T. Supuran. (2020) An update on drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 16:4, pages 297-307.
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Andrea Angeli & Claudiu T. Supuran. (2018) Treatment of sleep apnea with a combination of a carbonic anhydrase inhibitor and an aldosterone antagonist: a patent evaluation of CA2958110 and IN6616DEN2012. Expert Opinion on Therapeutic Patents 28:10, pages 723-727.
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Morteza Abdoli, Andrea Angeli, Murat Bozdag, Fabrizio Carta, Ali Kakanejadifard, Hamid Saeidian & Claudiu T. Supuran. (2017) Synthesis and carbonic anhydrase I, II, VII, and IX inhibition studies with a series of benzo[d]thiazole-5- and 6-sulfonamides. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1071-1078.
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Murat Bozdag, Silvia Bua, Sameh M. Osman, Zeid AlOthman & Claudiu T. Supuran. (2017) Carbonic anhydrase I, II, IV and IX inhibition with a series of 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 885-892.
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Marco Bragagni, Fabrizio Carta, Sameh M. Osman, Zeid AlOthman & Claudiu T. Supuran. (2017) Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 701-706.
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Erol Licsandru, Muhammet Tanc, Istvan Kocsis, Mihail Barboiu & Claudiu T. Supuran. (2017) A class of carbonic anhydrase I – selective activators. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 37-46.
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F. Zehra Küçükbay, Hasan Küçükbay, Muhammet Tanc & Claudiu T. Supuran. (2016) Synthesis and carbonic anhydrase I, II, IV and XII inhibitory properties of N-protected amino acid – sulfonamide conjugates. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 1476-1483.
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Ozen Ozensoy Guler, Clemente Capasso & Claudiu T. Supuran. (2016) A magnificent enzyme superfamily: carbonic anhydrases, their purification and characterization. Journal of Enzyme Inhibition and Medicinal Chemistry 31:5, pages 689-694.
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Claudiu T. Supuran. (2016) Carbonic anhydrase inhibition and the management of neuropathic pain. Expert Review of Neurotherapeutics 16:8, pages 961-968.
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Claudiu T. Supuran. (2016) How many carbonic anhydrase inhibition mechanisms exist?. Journal of Enzyme Inhibition and Medicinal Chemistry 31:3, pages 345-360.
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Claudiu T. Supuran. (2016) Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 12:4, pages 423-431.
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Murat Bozdag, Fabrizio Carta, Daniela Vullo, Semra Isik, Zeid AlOthman, Sameh M. Osman, Andrea Scozzafava & Claudiu T. Supuran. (2016) Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae β-carbonic anhydrase. Journal of Enzyme Inhibition and Medicinal Chemistry 31:1, pages 132-136.
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Namrata Singasane, Prashant S. Kharkar, Mariangela Ceruso, Claudiu T. Supuran & Mrunmayee P. Toraskar. (2015) Inhibition of carbonic anhydrase isoforms I, II, IX and XII with Schiff’s bases incorporating iminoureido moieties. Journal of Enzyme Inhibition and Medicinal Chemistry 30:6, pages 901-907.
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Daniela Vullo, Semra Isik, Murat Bozdag, Fabrizio Carta & Claudiu T. Supuran. (2015) 7-Amino-3,4-dihydro-1H-quinolin-2-one, a compound similar to the substituted coumarins, inhibits α-carbonic anhydrases without hydrolysis of the lactam ring. Journal of Enzyme Inhibition and Medicinal Chemistry 30:5, pages 773-777.
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Claudiu T Supuran. (2015) Acetazolamide for the treatment of idiopathic intracranial hypertension. Expert Review of Neurotherapeutics 15:8, pages 851-856.
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Aditi Sharma, Meena Tiwari & Claudiu T. Supuran. (2014) Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX. Journal of Enzyme Inhibition and Medicinal Chemistry 29:2, pages 292-296.
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Fortunato Migliardini, Viviana De Luca, Vincenzo Carginale, Mosè Rossi, Pasquale Corbo, Claudiu T. Supuran & Clemente Capasso. (2014) Biomimetic CO2 capture using a highly thermostable bacterial α-carbonic anhydrase immobilized on a polyurethane foam. Journal of Enzyme Inhibition and Medicinal Chemistry 29:1, pages 146-150.
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Andrea Scozzafava, Claudiu T Supuran & Fabrizio Carta. (2013)
Antiobesity carbonic anhydrase inhibitors: a literature and patent review
. Expert Opinion on Therapeutic Patents 23:6, pages 725-735.
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Anna-Kaisa Harju, Fatemeh Bootorabi, Marianne Kuuslahti, Claudiu T. Supuran & Seppo Parkkila. (2013) Carbonic anhydrase III: A neglected isozyme is stepping into the limelight. Journal of Enzyme Inhibition and Medicinal Chemistry 28:2, pages 231-239.
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Articles from other publishers (51)
Walaa Hamada Abd-Allah, Mostafa Abd El-Mohsen Anwar, Eman R. Mohammed & Samir M. El Moghazy. (2023) Anticonvulsant Classes and Possible Mechanism of Actions. ACS Chemical Neuroscience 14:23, pages 4076-4092.
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Claudiu T. Supuran. (2023) A simple yet multifaceted 90 years old, evergreen enzyme: Carbonic anhydrase, its inhibition and activation. Bioorganic & Medicinal Chemistry Letters 93, pages 129411.
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Satyajit Khatua, Tanusri De Bhowmik & Srabani Taraphder. (2023) A Case Study on the Use of Binding Free Energies to Screen Inhibitors of Human Carbonic Anhydrase II. ChemPhysChem 24:10.
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Mackenzie Taylor & Junming Ho. (2023) MM/GBSA prediction of relative binding affinities of carbonic anhydrase inhibitors: effect of atomic charges and comparison with Autodock4Zn. Journal of Computer-Aided Molecular Design 37:4, pages 167-182.
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Xiaoqing Chen, Yilang Li, Xun Yuan, Wenchang Yuan, Conglin Li, Yue Zeng, Yuling Lian, Xiaoxia Qiu, Yuan Qin, Guiping Zhang, Xiawen Liu, Chengfeng Luo, Jian-Dong Luo & Ning Hou. (2022) Methazolamide Attenuates the Development of Diabetic Cardiomyopathy by Promoting β-Catenin Degradation in Type 1 Diabetic Mice. Diabetes 71:4, pages 795-811.
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Amena Ali, Abuzer Ali, Musarrat Husain Warsi, Mohammad Akhlaquer Rahman, Mohamed Jawed Ahsan & Faizul Azam. (2022) An Insight into the Structural Requirements and Pharmacophore Identification of Carbonic Anhydrase Inhibitors to Combat Oxidative Stress at High Altitudes: An In-Silico Approach. Current Issues in Molecular Biology 44:3, pages 1027-1045.
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Nicole Lemon, Elisa Canepa, Marc A. Ilies & Silvia Fossati. (2021) Carbonic Anhydrases as Potential Targets Against Neurovascular Unit Dysfunction in Alzheimer’s Disease and Stroke. Frontiers in Aging Neuroscience 13.
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Dandan Su, Yan Zhang, Sébastien Ulrich & Mihail Barboiu. (2021) Constitutional Dynamic Inhibition/Activation of Carbonic Anhydrases. ChemPlusChem 86:11, pages 1500-1510.
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Dmitry Dar'in, Grigory Kantin, Stanislav Kalinin, Tatiana Sharonova, Alexander Bunev, Gennady I. Ostapenko, Alessio Nocentini, Vladimir Sharoyko, Claudiu T. Supuran & Mikhail Krasavin. (2021) Investigation of 3-sulfamoyl coumarins against cancer-related IX and XII isoforms of human carbonic anhydrase as well as cancer cells leads to the discovery of 2-oxo-2H-benzo[h]chromene-3-sulfonamide – A new caspase-activating proapoptotic agent. European Journal of Medicinal Chemistry 222, pages 113589.
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Francesca Mancuso, Anna Di Fiore, Laura De Luca, Andrea Angeli, Giuseppina De Simone, Claudiu T. Supuran & Rosaria Gitto. (2021) Design, synthesis and biochemical evaluation of novel carbonic anhydrase inhibitors triggered by structural knowledge on hCA VII. Bioorganic & Medicinal Chemistry 44, pages 116279.
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Chi-Ren Huang, Hung-Yi Chuang, Nai-Ching Chen, Shu-Fang Chen, Chung-Yao Hsu & Yao-Chung Chuang. (2021) Zonisamide Therapy Reduces Metabolic Consequences and Diminishes Nonalcoholic Fatty Liver Disease in Patients with Epilepsy. Journal of Clinical Medicine 10:15, pages 3380.
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Tatiana Sharonova, Polina Paramonova, Stanislav Kalinin, Alexander Bunev, Rovshan Е. Gasanov, Alessio Nocentini, Vladimir Sharoyko, Tatiana B. Tennikova, Dmitry Dar’in, Claudiu T. Supuran & Mikhail Krasavin. (2021) Insertion of metal carbenes into the anilinic N–H bond of unprotected aminobenzenesulfonamides delivers low nanomolar inhibitors of human carbonic anhydrase IX and XII isoforms. European Journal of Medicinal Chemistry 218, pages 113352.
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Claudiu T. Supuran. (2021) Emerging role of carbonic anhydrase inhibitors. Clinical Science 135:10, pages 1233-1249.
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Silvia Bua, Raj Kumar Mongre, Manisha Tiwari & Claudiu T. Supuran. (2021) Discovery of Potent Carbonic Anhydrase Inhibitors as Effective Anticonvulsant Agents: Drug Design, Synthesis, and In Vitro and In Vivo Investigations. Journal of Medicinal Chemistry 64:6, pages 3100-3114.
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Cecilia Zavala-Tecuapetla, Manola Cuellar-Herrera & Hiram Luna-Munguia. (2020) Insights into Potential Targets for Therapeutic Intervention in Epilepsy. International Journal of Molecular Sciences 21:22, pages 8573.
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Aiga Grandāne, Alessio Nocentini, Ilona Domračeva, Raivis Žalubovskis & Claudiu T. Supuran. (2020) Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII. European Journal of Medicinal Chemistry 200, pages 112300.
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Aiga Grandane, Alessio Nocentini, Thomas Werner, Raivis Zalubovskis & Claudiu T. Supuran. (2020) Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors. Bioorganic & Medicinal Chemistry 28:11, pages 115496.
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Rita Meleddu, Simona Distinto, Filippo Cottiglia, Rossella Angius, Pierluigi Caboni, Andrea Angeli, Claudia Melis, Serenella Deplano, Stefano Alcaro, Francesco Ortuso, Claudiu T. Supuran & Elias Maccioni. (2020) New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII. ACS Medicinal Chemistry Letters 11:5, pages 852-856.
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Francesca Mancuso, Anna Di Fiore, Laura De Luca, Andrea Angeli, Simona M. Monti, Giuseppina De Simone, Claudiu T. Supuran & Rosaria Gitto. (2020) Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms. ACS Medicinal Chemistry Letters 11:5, pages 1000-1005.
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Ayşegül Sümer, Eşref Edip Keha, Ahmet Menteşe & Ahmet Alver. (2020) Effects of topiramate on adipocyte differentiation and gene expression of certain carbonic anhydrase isoenzymes. Turkish Journal of Biochemistry 45:2, pages 121-129.
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Daniela Vullo, Ronny Lehneck, William A. Donald, Stefanie Pöggeler & Claudiu T. Supuran. (2020) Sulfonamide Inhibition Studies of the β-Class Carbonic Anhydrase CAS3 from the Filamentous Ascomycete Sordaria macrospora. Molecules 25:5, pages 1036.
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Murat Bozdag, Abdulmalik Saleh Alfawaz Altamimi, Daniela Vullo, Claudiu T. Supuran & Fabrizio Carta. (2019) State of the Art on Carbonic Anhydrase Modulators for Biomedical Purposes. Current Medicinal Chemistry 26:15, pages 2558-2573.
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Prete, Angeli, Ghobril, Hitce, Clavaud, Marat, Supuran & Capasso. (2019) Anion Inhibition Profile of the β-Carbonic Anhydrase from the Opportunist Pathogenic Fungus Malassezia Restricta Involved in Dandruff and Seborrheic Dermatitis. Metabolites 9:7, pages 147.
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Meng‐Tsang Hsieh, Ping‐Tao Tseng, Yi‐Cheng Wu, Yu‐Kang Tu, Hung‐Chi Wu, Chih‐Wei Hsu, Wei‐Te Lei, Brendon Stubbs, Andre F. Carvalho, Chih‐Sung Liang, Ta‐Chuan Yeh, Tien‐Yu Chen, Che‐Sheng Chu, Juo‐Chi Li, Chia‐Ling Yu, Yen‐Wen Chen & Dian‐Jeng Li. (2019) Effects of different pharmacologic smoking cessation treatments on body weight changes and success rates in patients with nicotine dependence: A network meta‐analysis. Obesity Reviews 20:6, pages 895-905.
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Damiano Tanini, Antonella Capperucci, Claudiu T. Supuran & Andrea Angeli. (2019) Sulfur, selenium and tellurium containing amines act as effective carbonic anhydrase activators. Bioorganic Chemistry 87, pages 516-522.
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Sonia Del Prete, Daniela Vullo, Cynthia Ghobril, Julien Hitce, Cécile Clavaud, Xavier Marat, Clemente Capasso & Claudiu T. Supuran. (2019) Cloning, Purification, and Characterization of a β-Carbonic Anhydrase from Malassezia restricta, an Opportunistic Pathogen Involved in Dandruff and Seborrheic Dermatitis. International Journal of Molecular Sciences 20:10, pages 2447.
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Maria Rosa Buemi, Anna Di Fiore, Laura De Luca, Andrea Angeli, Francesca Mancuso, Stefania Ferro, Simona Maria Monti, Martina Buonanno, Emilio Russo, Giovanbattista De Sarro, Giuseppina De Simone, Claudiu T. Supuran & Rosaria Gitto. (2019) Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. European Journal of Medicinal Chemistry 163, pages 443-452.
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Andrea Angeli, Damiano Tanini, Alessio Nocentini, Antonella Capperucci, Marta Ferraroni, Paola Gratteri & Claudiu T. Supuran. (2019) Selenols: a new class of carbonic anhydrase inhibitors. Chemical Communications 55:5, pages 648-651.
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Nasr Y. Khalil, Haitham K. AlRabiah, Saad S. AL Rashoud, Ahmed Bari & Tanveer A. Wani. 2019. Profiles of Drug Substances, Excipients, and Related Methodology. Profiles of Drug Substances, Excipients, and Related Methodology
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Silvia Bua, Manisha Tiwari & Claudiu T. Supuran. (2018) Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation. Journal of Medicinal Chemistry 61:7, pages 3151-3165.
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Ylenia Cau, Daniela Vullo, Mattia Mori, Elena Dreassi, Claudiu Supuran & Maurizio Botta. (2017) Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII. Molecules 23:1, pages 17.
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Elvira Bruno, Maria Rosa Buemi, Anna Di Fiore, Laura De Luca, Stefania Ferro, Andrea Angeli, Roberto Cirilli, Daniele Sadutto, Vincenzo Alterio, Simona Maria Monti, Claudiu T. Supuran, Giuseppina De Simone & Rosaria Gitto. (2017) Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides. Journal of Medicinal Chemistry 60:10, pages 4316-4326.
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Riccardo Nescatelli, Simone Carradori, Federico Marini, Vicky Caponigro, Remo Bucci, Celeste De Monte, Adriano Mollica, Luisa Mannina, Mariangela Ceruso, Claudiu T. Supuran & Daniela Secci. (2017) Geographical characterization by MAE-HPLC and NIR methodologies and carbonic anhydrase inhibition of Saffron components. Food Chemistry 221, pages 855-863.
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Menshawy A. Mohamed, Alaa A.-M. Abdel-Aziz, Helmy M. Sakr, Adel S. El-Azab, Silvia Bua & Claudiu T. Supuran. (2017) Synthesis and human/bacterial carbonic anhydrase inhibition with a series of sulfonamides incorporating phthalimido moieties. Bioorganic & Medicinal Chemistry 25:8, pages 2524-2529.
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Claudiu T. Supuran. (2016) Structure and function of carbonic anhydrases. Biochemical Journal 473:14, pages 2023-2032.
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Giosuè Costa, Maria Concetta Gidaro, Daniela Vullo, Claudiu T. Supuran & Stefano Alcaro. (2016) Active Components of Essential Oils as Anti-Obesity Potential Drugs Investigated by in Silico Techniques. Journal of Agricultural and Food Chemistry 64:26, pages 5295-5300.
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Maria Rosa Buemi, Laura De Luca, Stefania Ferro, Elvira Bruno, Mariangela Ceruso, Claudiu T. Supuran, Klára Pospíšilová, Jiří Brynda, Pavlína Řezáčová & Rosaria Gitto. (2015) Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. European Journal of Medicinal Chemistry 102, pages 223-232.
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Sonia Del Prete, Viviana De Luca, Elena Iandolo, Claudiu T. Supuran & Clemente Capasso. (2015) Protonography, a powerful tool for analyzing the activity and the oligomeric state of the γ-carbonic anhydrase identified in the genome of Porphyromonas gingivalis. Bioorganic & Medicinal Chemistry 23:13, pages 3747-3750.
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Mustafa Durgun, Hasan Turkmen, Mariangela Ceruso & Claudiu T. Supuran. (2015) Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII. Bioorganic & Medicinal Chemistry Letters 25:11, pages 2377-2381.
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Luca Costantino & Daniela Barlocco. (2015) New perspectives on the development of antiobesity drugs. Future Medicinal Chemistry 7:3, pages 315-336.
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Özlen Güzel-Akdemir, Atilla Akdemir, Nilgün Karalı & Claudiu T. Supuran. (2015) Discovery of novel isatin-based sulfonamides with potent and selective inhibition of the tumor-associated carbonic anhydrase isoforms IX and XII. Organic & Biomolecular Chemistry 13:23, pages 6493-6499.
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V. Alterio, M. Tanc, J. Ivanova, R. Zalubovskis, I. Vozny, S. M. Monti, A. Di Fiore, G. De Simone & C. T. Supuran. (2015) X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor. Organic & Biomolecular Chemistry 13:13, pages 4064-4069.
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Busra Sarikaya, Mariangela Ceruso, Fabrizio Carta & Claudiu T. Supuran. (2014) Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: Identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones. Bioorganic & Medicinal Chemistry 22:21, pages 5883-5890.
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Aiga Grandane, Muhammet Tanc, Raivis Zalubovskis & Claudiu T. Supuran. (2014) 6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII. Bioorganic & Medicinal Chemistry Letters 24:5, pages 1256-1260.
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Aiga Grandane, Muhammet Tanc, Raivis Zalubovskis & Claudiu T. Supuran. (2014) Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII. Bioorganic & Medicinal Chemistry 22:5, pages 1522-1528.
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Ramazan Ulus, İbrahim Yeşildağ, Muhammet Tanç, Metin Bülbül, Muharrem Kaya & Claudiu T. Supuran. (2013) Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII. Bioorganic & Medicinal Chemistry 21:18, pages 5799-5805.
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Janis Leitans, Agnese Sprudza, Muhammet Tanc, Igor Vozny, Raivis Zalubovskis, Kaspars Tars & Claudiu T. Supuran. (2013) 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: Solution and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry 21:17, pages 5130-5138.
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Muhammet Tanc, Fabrizio Carta, Murat Bozdag, Andrea Scozzafava & Claudiu T. Supuran. (2013) 7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors. Bioorganic & Medicinal Chemistry 21:15, pages 4502-4510.
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Gul N. Shah, Timothy S. Rubbelke, Joshua Hendin, Hien Nguyen, Abdul Waheed, James D. Shoemaker & William S. Sly. (2013) Targeted mutagenesis of mitochondrial carbonic anhydrases VA and VB implicates both enzymes in ammonia detoxification and glucose metabolism. Proceedings of the National Academy of Sciences 110:18, pages 7423-7428.
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L.M. Berreau. 2013. Comprehensive Inorganic Chemistry II. Comprehensive Inorganic Chemistry II
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Meir Bialer. (2012) Why are antiepileptic drugs used for nonepileptic conditions?. Epilepsia 53, pages 26-33.
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