4,007
Views
129
CrossRef citations to date
0
Altmetric
SPECIAL FOCUS: RNA Vaccines - Review

mRNA transcript therapy

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Wubetu Yihunie, Getinet Nibret & Yibeltal Aschale. (2023) Recent Advances in Messenger Ribonucleic Acid (mRNA) Vaccines and Their Delivery Systems: A Review. Clinical Pharmacology: Advances and Applications 15, pages 77-98.
Read now
Akon Higuchi, Tzu-Cheng Sung, Ting Wang, Qing-Dong Ling, S. Suresh Kumar, Shih-Tien Hsu & Akihiro Umezawa. (2023) Material Design for Next-Generation mRNA Vaccines Using Lipid Nanoparticles. Polymer Reviews 63:2, pages 394-436.
Read now
Evalyne M Jansen, Henderik W Frijlink, Wouter LJ Hinrichs & Mitchel JR Ruigrok. (2022) Are inhaled mRNA vaccines safe and effective? A review of preclinical studies. Expert Opinion on Drug Delivery 19:11, pages 1471-1485.
Read now
Kenneth K.W. To & William C.S. Cho. (2021) An overview of rational design of mRNA-based therapeutics and vaccines. Expert Opinion on Drug Discovery 16:11, pages 1307-1317.
Read now
Iván del Moral-Sánchez & Kwinten Sliepen. (2019) Strategies for inducing effective neutralizing antibody responses against HIV-1. Expert Review of Vaccines 18:11, pages 1127-1143.
Read now
Ilona Kocmik, Karolina Piecyk, Magdalena Rudzinska, Anna Niedzwiecka, Edward Darzynkiewicz, Renata Grzela & Marzena Jankowska-Anyszka. (2018) Modified ARCA analogs providing enhanced translational properties of capped mRNAs. Cell Cycle 17:13, pages 1624-1636.
Read now
Philipp Reautschnig, Paul Vogel & Thorsten Stafforst. (2017) The notorious R.N.A. in the spotlight - drug or target for the treatment of disease. RNA Biology 14:5, pages 651-668.
Read now
Ying K. Tam, Thomas D. Madden & Michael J. Hope. (2016) Pieter Cullis’ quest for a lipid-based, fusogenic delivery system for nucleic acid therapeutics: success with siRNA so what about mRNA?. Journal of Drug Targeting 24:9, pages 774-779.
Read now

Articles from other publishers (121)

Fatima Rizvi, Yu-Ri Lee, Ricardo Diaz-Aragon, Pushpinder S. Bawa, Juhoon So, Rodrigo M. Florentino, Susan Wu, Arianna Sarjoo, Emily Truong, Anna R. Smith, Feiya Wang, Elissa Everton, Alina Ostrowska, Kyounghwa Jung, Ying Tam, Hiromi Muramatsu, Norbert Pardi, Drew Weissman, Alejandro Soto-Gutierrez, Donghun Shin & Valerie Gouon-Evans. (2023) VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis. Cell Stem Cell 30:12, pages 1640-1657.e8.
Crossref
Bingchen Li & Erwin London. (2023) Inner leaflet cationic lipid increases nucleic acid loading independently of outer leaflet lipid charge in asymmetric liposomes. Methods 219, pages 16-21.
Crossref
Swarda Deo, Kaushik Desai, Aishwarya Patare, Rucha Wadapurkar, Saniya Rade, Siddhi Mahudkar, Madhura Sathe, Shalini Srivastava, Pragya Prasanna & Ajay Singh. (2023) Evaluation of self-amplifying mRNA platform for protein expression and genetic stability: Implication for mRNA therapies. Biochemical and Biophysical Research Communications 680, pages 108-118.
Crossref
Alexey D. Perenkov, Alena D. Sergeeva, Maria V. Vedunova & Dmitri V. Krysko. (2023) In Vitro Transcribed RNA-Based Platform Vaccines: Past, Present, and Future. Vaccines 11:10, pages 1600.
Crossref
Falak Goyal, Anandini Chattopadhyay, Umashanker Navik, Aklank Jain, P. Hemachandra Reddy, Gurjit Kaur Bhatti & Jasvinder Singh Bhatti. (2023) Advancing Cancer Immunotherapy: The Potential of mRNA Vaccines As a Promising Therapeutic Approach. Advanced Therapeutics.
Crossref
Tian Tan, Shu-Ting Deng, Bing-Huo Wu, Qi Yang, Meng-Wan Wu, Hong Wu, Chen-Hui Cao & Chuan Xu. (2023) mRNA Vaccine - A New Cancer Treatment Strategy. Current Cancer Drug Targets 23:9, pages 669-681.
Crossref
Yunfeng Yan, Xiaomin Liu, Longyu Wang, Chengfan Wu, Qi Shuai, Yanmei Zhang & Shuai Liu. (2023) Branched hydrophobic tails in lipid nanoparticles enhance mRNA delivery for cancer immunotherapy. Biomaterials 301, pages 122279.
Crossref
Karol Kurpiejewski, Marzena Jankowska-Anyszka & Renata Grzela. (2023) N2 modified cap analogues as translation inhibitors and substrates for preparation of therapeutic mRNA. European Biophysics Journal 52:6-7, pages 511-519.
Crossref
Yahya F Jamous & Dalal A Alhomoud. (2023) The Safety and Effectiveness of mRNA Vaccines Against SARS-CoV-2. Cureus.
Crossref
Ahmet Hınçer, Recep Erdem Ahan, Ebru Aras & Urartu Özgür Şafak Şeker. (2023) Making the Next Generation of Therapeutics: mRNA Meets Synthetic Biology. ACS Synthetic Biology 12:9, pages 2505-2515.
Crossref
Londiwe Simphiwe Mbatha, Jude Akinyelu, Fiona Maiyo & Tukayi Kudanga. (2023) Future prospects in mRNA vaccine development. Biomedical Materials 18:5, pages 052006.
Crossref
Jingjing Zhang, Yuheng Liu, Chao Li, Qin Xiao, Dandan Zhang, Yang Chen, Joseph Rosenecker, Xiaoyan Ding & Shan Guan. (2023) Recent Advances and Innovations in the Preparation and Purification of In Vitro-Transcribed-mRNA-Based Molecules. Pharmaceutics 15:9, pages 2182.
Crossref
Sepehr Dehghani-Ghahnaviyeh, Michael Smith, Yan Xia, Athanasios Dousis, Alan Grossfield & Sreyoshi Sur. (2023) Ionizable Amino Lipids Distribution and Effects on DSPC/Cholesterol Membranes: Implications for Lipid Nanoparticle Structure. The Journal of Physical Chemistry B 127:31, pages 6928-6939.
Crossref
Victor Solodushko & Brian Fouty. (2023) Terminal hairpins improve protein expression in IRES-initiated mRNA in the absence of a cap and polyadenylated tail. Gene Therapy 30:7-8, pages 620-627.
Crossref
Dongqiao Li, Cynthia Liu, Yingzhu Li, Rumiana Tenchov, Janet M. Sasso, Di Zhang, Dan Li, Lixue Zou, Xuezhao Wang & Qiongqiong Zhou. (2023) Messenger RNA-Based Therapeutics and Vaccines: What’s beyond COVID-19?. ACS Pharmacology & Translational Science 6:7, pages 943-969.
Crossref
Guilherme J. Guimaraes, Jaeah Kim & Michael G. Bartlett. (2023) Characterization of mRNA therapeutics. Mass Spectrometry Reviews.
Crossref
Edit Oláh. (2023) Learning from cancer to address COVID-19. Biologia Futura 74:1-2, pages 29-43.
Crossref
Wei Yang, Jianwei Cao, Hui Cheng, Liang Chen, Meihua Yu, Yu Chen & Xingang Cui. (2023) Nanoformulations targeting immune cells for cancer therapy: mRNA therapeutics. Bioactive Materials 23, pages 438-470.
Crossref
Huan-Huan Wei, Liangliang Zheng & Zefeng Wang. (2023) mRNA therapeutics: New vaccination and beyond. Fundamental Research.
Crossref
Eugenia A. Panova, Denis A. Kleymenov, Dmitry V. Shcheblyakov, Evgeniia N. Bykonia, Elena P. Mazunina, Alina S. Dzharullaeva, Anastasia N. Zolotar, Artem A. Derkaev, Ilias B. Esmagambetov, Ivan I. Sorokin, Evgeny V. Usachev, Anatoly N. Noskov, Igor A. Ivanov, Timofei S. Zatsepin, Sergey E. Dmitriev, Vladimir A. Gushchin, Boris S. Naroditsky, Denis Y. Logunov & Alexander L. Gintsburg. (2023) Single-domain antibody delivery using an mRNA platform protects against lethal doses of botulinum neurotoxin A. Frontiers in Immunology 14.
Crossref
Renata Grzela, Karolina Piecyk, Anna Stankiewicz-Drogon, Paulina Pietrow, Maciej Lukaszewicz, Karol Kurpiejewski, Edward Darzynkiewicz & Marzena Jankowska-Anyszka. (2023) N2 modified dinucleotide cap analogs as a potent tool for mRNA engineering. RNA 29:2, pages 200-216.
Crossref
Wenhui Zha, Ji Wang, Zongke Guo, Yanhao Zhang, Yang Wang, Shuo Dong, Chao Liu, Hanlei Xing & Xinsong Li. (2023) Efficient delivery of VEGF-A mRNA for promoting diabetic wound healing via ionizable lipid nanoparticles. International Journal of Pharmaceutics 632, pages 122565.
Crossref
Yu Liu, Xu Liu, Jiaxin Huang, Yingying Shi, Zhenyu Luo, Junlei Zhang, Xuemeng Guo, Mengshi Jiang, Xiang Li, Hang Yin, Bing Qin, Guannan Guan, Lihua Luo, Yun Zhou & Jian You. (2022) Nonlysosomal Route of mRNA Delivery and Combining with Epigenetic Regulation Optimized Antitumor Immunoprophylactic Efficacy. Advanced Healthcare Materials 12:4.
Crossref
Yuan Yuan, Fan Gao, Ying Chang, Qiu Zhao & Xingxing He. (2023) Advances of mRNA vaccine in tumor: a maze of opportunities and challenges. Biomarker Research 11:1.
Crossref
Raquel Martinez-Campelo & Marcos Garcia-Fuentes. (2023) Matrices Activated with Messenger RNA. Journal of Functional Biomaterials 14:1, pages 48.
Crossref
Androulla N. Miliotou, Parthena F. Foltopoulou, Alexandra Ingendoh-Tsakmakidis, Asterios S. Tsiftsoglou, Ioannis S. Vizirianakis, Ioannis S. Pappas & Lefkothea C. Papadopoulou. (2023) Protein Transduction Domain-Mediated Delivery of Recombinant Proteins and In Vitro Transcribed mRNAs for Protein Replacement Therapy of Human Severe Genetic Mitochondrial Disorders: The Case of Sco2 Deficiency. Pharmaceutics 15:1, pages 286.
Crossref
Christin Schmidt & Barbara S. Schnierle. (2023) Self-Amplifying RNA Vaccine Candidates: Alternative Platforms for mRNA Vaccine Development. Pathogens 12:1, pages 138.
Crossref
Shuo Dong, Ji Wang, Zongke Guo, Yanhao Zhang, Wenhui Zha, Yang Wang, Chao Liu, Hanlei Xing & Xinsong Li. (2023) Efficient delivery of VEGFA mRNA for promoting wound healing via ionizable lipid nanoparticles. Bioorganic & Medicinal Chemistry 78, pages 117135.
Crossref
Simone Pecetta, S. Sohail Ahmed, Ronald Ellis & Rino Rappuoli. 2023. Plotkin's Vaccines. Plotkin's Vaccines 1350 1373.e9 .
Walter Gottlieb LandWalter Gottlieb Land. 2023. Damage-Associated Molecular Patterns in Human Diseases. Damage-Associated Molecular Patterns in Human Diseases 203 284 .
Md. Emranul Karim, Sheikh Tanzina Haque, Hamed Al-Busaidi, Athirah Bakhtiar, Kyi Kyi Tha, Mark M. Banaszak Holl & Ezharul Hoque Chowdhury. (2022) Scope and challenges of nanoparticle-based mRNA delivery in cancer treatment. Archives of Pharmacal Research 45:12, pages 865-893.
Crossref
Denzil Furtado, Christina Cortez-Jugo, Ya Hui Hung, Ashley I. Bush & Frank Caruso. (2022) mRNA Treatment Rescues Niemann–Pick Disease Type C1 in Patient Fibroblasts. Molecular Pharmaceutics 19:11, pages 3987-3999.
Crossref
Rachel Skelton, Arantxa Roach, Lauren E. Prudhomme, Jing Yu Carolina Cen Feng, Pooja Gaikwad & Ryan M. Williams. (2022) Formulation of Lipid-Free Polymeric Mesoscale Nanoparticles Encapsulating mRNA. Pharmaceutical Research 39:11, pages 2699-2707.
Crossref
Yi-Han Zuo, Xiao-Ping Zhao & Xing-Xing Fan. (2022) Nanotechnology-based chimeric antigen receptor T-cell therapy in treating solid tumor. Pharmacological Research 184, pages 106454.
Crossref
Lu Yang, Lin Tang, Ming Zhang & Chaoyong Liu. (2022) Recent Advances in the Molecular Design and Delivery Technology of mRNA for Vaccination Against Infectious Diseases. Frontiers in Immunology 13.
Crossref
Albert Liu & Xiao Wang. (2022) The Pivotal Role of Chemical Modifications in mRNA Therapeutics. Frontiers in Cell and Developmental Biology 10.
Crossref
Qing He, Hua Gao, Dejiang Tan, Heng Zhang & Jun-zhi Wang. (2022) mRNA cancer vaccines: Advances, trends and challenges. Acta Pharmaceutica Sinica B 12:7, pages 2969-2989.
Crossref
Shugang Qin, Xiaoshan Tang, Yuting Chen, Kepan Chen, Na Fan, Wen Xiao, Qian Zheng, Guohong Li, Yuqing Teng, Min Wu & Xiangrong Song. (2022) mRNA-based therapeutics: powerful and versatile tools to combat diseases. Signal Transduction and Targeted Therapy 7:1.
Crossref
Maochen Li, Han Wang, Lili Tian, Zehan Pang, Qingkun Yang, Tianqi Huang, Junfen Fan, Lihua Song, Yigang Tong & Huahao Fan. (2022) COVID-19 vaccine development: milestones, lessons and prospects. Signal Transduction and Targeted Therapy 7:1.
Crossref
Kamil BATUR & Hakan YARDIMCI. (2022) mRNA AŞILARINDA GÜNCEL YAKLAŞIMLARCURRENT APPROACHES to mRNA VACCINES. Veteriner Farmakoloji ve Toksikoloji Derneği Bülteni 13:1, pages 1-10.
Crossref
Tomislav Domazet-Lošo. (2022) mRNA Vaccines: Why Is the Biology of Retroposition Ignored?. Genes 13:5, pages 719.
Crossref
Fatemeh Nafian, Simin Nafian, Ghazal Soleymani, Zahra Pourmanouchehri, Mahnaz Kiyanjam, Sharareh Berenji Jalaei, Hanie Jeyroudi & Sayed Mohammad Mohammdi. 2022. Vaccine Development. Vaccine Development.
Sita Awasthi & Harvey M. Friedman. (2022) An mRNA vaccine to prevent genital herpes. Translational Research 242, pages 56-65.
Crossref
Elizabeth Rosado Balmayor. (2022) Synthetic mRNA – emerging new class of drug for tissue regeneration. Current Opinion in Biotechnology 74, pages 8-14.
Crossref
Enyue Fang, Xiaohui Liu, Miao Li, Zelun Zhang, Lifang Song, Baiyu Zhu, Xiaohong Wu, Jingjing Liu, Danhua Zhao & Yuhua Li. (2022) Advances in COVID-19 mRNA vaccine development. Signal Transduction and Targeted Therapy 7:1.
Crossref
Yi Lin, Ernst Wagner & Ulrich Lächelt. (2022) Non-viral delivery of the CRISPR/Cas system: DNA versus RNA versus RNP . Biomaterials Science 10:5, pages 1166-1192.
Crossref
Hanieh Moradian, Toralf Roch, Larissa Anthofer, Andreas Lendlein & Manfred Gossen. (2022) Chemical modification of uridine modulates mRNA-mediated proinflammatory and antiviral response in primary human macrophages. Molecular Therapy - Nucleic Acids 27, pages 854-869.
Crossref
Rodolfo E. De La Vega, Martijn van Griensven, Wen ZhangMichael J. CoenenChristopher V. Nagelli, Joseph A. PanosCarlos J. Peniche Silva, Johannes GeigerChristian Plank, Christopher H. Evans & Elizabeth R. Balmayor. (2022) Efficient healing of large osseous segmental defects using optimized chemically modified messenger RNA encoding BMP-2. Science Advances 8:7.
Crossref
Edo Kon, Uri Elia & Dan Peer. (2022) Principles for designing an optimal mRNA lipid nanoparticle vaccine. Current Opinion in Biotechnology 73, pages 329-336.
Crossref
Sheema Mir. (2022) Hantavirus Induced Kidney Disease. Frontiers in Medicine 8.
Crossref
Joel G. Rurik, István Tombácz, Amir Yadegari, Pedro O. Méndez Fernández, Swapnil V. ShewaleLi Li, Toru Kimura, Ousamah Younoss Soliman, Tyler E. Papp, Ying K. TamBarbara L. MuiSteven M. Albelda, Ellen Puré, Carl H. June, Haig Aghajanian, Drew Weissman, Hamideh Parhiz & Jonathan A. Epstein. (2022) CAR T cells produced in vivo to treat cardiac injury. Science 375:6576, pages 91-96.
Crossref
Jiao Wei & Aimin Hui. (2022) Review of Ribosome Interactions with SARS-CoV-2 and COVID-19 mRNA Vaccine. Life 12:1, pages 57.
Crossref
Aline Yen Ling Wang. (2022) Modified mRNA-Based Vaccines Against Coronavirus Disease 2019. Cell Transplantation 31, pages 096368972210902.
Crossref
Itziar Gómez-Aguado, Julen Rodríguez-Castejón, Marina Beraza-Millor, Alicia Rodríguez-Gascón, Ana del Pozo-Rodríguez & María Ángeles Solinís. 2022. mRNA-Based Therapeutics. mRNA-Based Therapeutics 207 293 .
Frantisek Drafi, Silvester Ponist, Bruno Sepodes & Katarina Bauerova. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology 321 341 .
Lei Miao, Yu Zhang & Leaf Huang. (2021) mRNA vaccine for cancer immunotherapy. Molecular Cancer 20:1.
Crossref
Androulla N. Miliotou, Ioannis S. Pappas, George Spyroulias, Efthimia Vlachaki, Asterios S. Tsiftsoglou, Ioannis S. Vizirianakis & Lefkothea C. Papadopoulou. (2021) Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders. Molecular Therapy - Nucleic Acids 26, pages 694-710.
Crossref
Ana Krhač Levačić, Simone Berger, Judith Müller, Andrea Wegner, Ulrich Lächelt, Christian Dohmen, Carsten Rudolph & Ernst Wagner. (2021) Dynamic mRNA polyplexes benefit from bioreducible cleavage sites for in vitro and in vivo transfer. Journal of Controlled Release 339, pages 27-40.
Crossref
Steven A. Berkowitz & Thomas Laue. (2021) Boundary convection during sedimentation velocity in the Optima analytical ultracentrifuge. Analytical Biochemistry 631, pages 114306.
Crossref
Rundong Feng, Suryaji Patil, Xin Zhao, Zhiping Miao & Airong Qian. (2021) RNA Therapeutics - Research and Clinical Advancements. Frontiers in Molecular Biosciences 8.
Crossref
Guangna Liu, Motao Zhu, Xiao Zhao & Guangjun Nie. (2021) Nanotechnology-empowered vaccine delivery for enhancing CD8+ T cells-mediated cellular immunity. Advanced Drug Delivery Reviews 176, pages 113889.
Crossref
Alireza Shahryari, Ingo Burtscher, Zahra Nazari & Heiko Lickert. (2021) Engineering Gene Therapy: Advances and Barriers. Advanced Therapeutics 4:9.
Crossref
Subbiah Jeeva, Ki-Hye Kim, Chong Hyun Shin, Bao-Zhong Wang & Sang-Moo Kang. (2021) An Update on mRNA-Based Viral Vaccines. Vaccines 9:9, pages 965.
Crossref
Chiranjib Chakraborty, Ashish Ranjan Sharma, Manojit Bhattacharya & Sang-Soo Lee. (2021) From COVID-19 to Cancer mRNA Vaccines: Moving From Bench to Clinic in the Vaccine Landscape. Frontiers in Immunology 12.
Crossref
Xuhua Xia. (2021) Detailed Dissection and Critical Evaluation of the Pfizer/BioNTech and Moderna mRNA Vaccines. Vaccines 9:7, pages 734.
Crossref
Tufan Gökirmak, Mehran Nikan, Svenja Wiechmann, Thazha P. Prakash, Michael Tanowitz & Punit P. Seth. (2021) Overcoming the challenges of tissue delivery for oligonucleotide therapeutics. Trends in Pharmacological Sciences 42:7, pages 588-604.
Crossref
Jingsong Cao, Minjung Choi, Eleonora Guadagnin, Maud Soty, Marine Silva, Vincent Verzieux, Edward Weisser, Arianna Markel, Jenny Zhuo, Shi Liang, Ling Yin, Andrea Frassetto, Anne-Renee Graham, Kristine Burke, Tatiana Ketova, Cosmin Mihai, Zach Zalinger, Becca Levy, Gilles Besin, Meredith Wolfrom, Barbara Tran, Christopher Tunkey, Erik Owen, Joe Sarkis, Athanasios Dousis, Vladimir Presnyak, Christopher Pepin, Wei Zheng, Lei Ci, Marjie Hard, Edward Miracco, Lisa Rice, Vi Nguyen, Mike Zimmer, Uma Rajarajacholan, Patrick F. Finn, Gilles Mithieux, Fabienne Rajas, Paolo G. V. Martini & Paloma H. Giangrande. (2021) mRNA therapy restores euglycemia and prevents liver tumors in murine model of glycogen storage disease. Nature Communications 12:1.
Crossref
Niall McMullan. 2021. Molecular Biology and Biotechnology. Molecular Biology and Biotechnology 440 488 .
Yingzhu Li, Rumiana Tenchov, Jeffrey Smoot, Cynthia Liu, Steven Watkins & Qiongqiong Zhou. (2021) A Comprehensive Review of the Global Efforts on COVID-19 Vaccine Development. ACS Central Science 7:4, pages 512-533.
Crossref
Prafulla Kumar Padhi & Feranando Charrua-Santos. (2021) Quantum Biotech and Internet of Virus Things: Towards a Theoretical Framework. Applied System Innovation 4:2, pages 27.
Crossref
Omnia Fayed, Martijn van Griensven, Zeinab Tahmasebi Birgani, Christian Plank & Elizabeth R. Balmayor. (2021) Transcript-Activated Coatings on Titanium Mediate Cellular Osteogenesis for Enhanced Osteointegration. Molecular Pharmaceutics 18:3, pages 1121-1137.
Crossref
Sean Mc Cafferty, Joyca De Temmerman, Tasuku Kitada, Jacob R. Becraft, Ron Weiss, Darrell J. Irvine, Mathias Devreese, Siegrid De Baere, Francis Combes & Niek N. Sanders. (2021) In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation. Molecular Therapy 29:3, pages 1164-1173.
Crossref
Tsvetelina Velikova & Tsvetoslav Georgiev. (2021) SARS-CoV-2 vaccines and autoimmune diseases amidst the COVID-19 crisis. Rheumatology International 41:3, pages 509-518.
Crossref
Fatima Rizvi, Elissa Everton, Anna R. Smith, Hua Liu, Elizabeth Osota, Mitchell Beattie, Ying Tam, Norbert Pardi, Drew Weissman & Valerie Gouon-Evans. (2021) Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA. Nature Communications 12:1.
Crossref
Goodluck Anthony Kelechi Ohanube & Uchejeso Mark Obeta. (2021) mRNA Vaccine: Determinants of Clinical Efficacy, and Optimization of Pharmacological Effects. International Journal Of Pharmaceutical And Phytopharmacological Research 11:5, pages 1-10.
Crossref
Mi Tian, Tao Wang & Peng Wang. (2021) Development and Clinical Validation of a Seven-Gene Prognostic Signature Based on Multiple Machine Learning Algorithms in Kidney Cancer. Cell Transplantation 30, pages 096368972096917.
Crossref
Vikas Kushwaha, Anuprabha & R. C. Sobti. 2021. Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications. Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications 273 287 .
Maria L. Guevara, Francesca Persano & Stefano Persano. (2020) Advances in Lipid Nanoparticles for mRNA-Based Cancer Immunotherapy. Frontiers in Chemistry 8.
Crossref
A. Katharina Kolonko, Janes Efing, Yadira González-Espinosa, Nadine Bangel-Ruland, Willy van Driessche, Francisco M. Goycoolea & Wolf-Michael Weber. (2020) Capsaicin-Loaded Chitosan Nanocapsules for wtCFTR-mRNA Delivery to a Cystic Fibrosis Cell Line. Biomedicines 8:9, pages 364.
Crossref
Shuqin Xu, Kunpeng Yang, Rose Li & Lu Zhang. (2020) mRNA Vaccine Era—Mechanisms, Drug Platform and Clinical Prospection. International Journal of Molecular Sciences 21:18, pages 6582.
Crossref
M. Yu. Nikitina, A. A. Ponomareva, A. G. Daminova, T. A. Nevzorova, Ya. V. Tarakanchikova, E. N. Atochina-Wasserman & R. I. Litvinov. (2020) Viability, Ultrastructure, and Migration Activity of Neutrophils after Phagocytosis of Synthetic Microcapsules. Cell and Tissue Biology 14:4, pages 275-285.
Crossref
Tingting Shen, Yu Zhang, Shurong Zhou, Shuibin Lin, Xiao-Bing Zhang & Guizhi Zhu. (2020) Nucleic Acid Immunotherapeutics for Cancer. ACS Applied Bio Materials 3:5, pages 2838-2849.
Crossref
Yuhua Weng, Chunhui Li, Tongren Yang, Bo Hu, Mengjie Zhang, Shuai Guo, Haihua Xiao, Xing-Jie Liang & Yuanyu Huang. (2020) The challenge and prospect of mRNA therapeutics landscape. Biotechnology Advances 40, pages 107534.
Crossref
Shuhui LimRegina KhooKhong Ming PehJinkai TeoShih Chieh ChangSimon NgGreg L. BeilhartzRoman A. MelnykCharles W. Johannes, Christopher J. Brown, David P. Lane, Brian HenryAnthony W. Partridge. (2020) bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA). Proceedings of the National Academy of Sciences 117:11, pages 5791-5800.
Crossref
Sergio Linares-Fernández, Céline Lacroix, Jean-Yves Exposito & Bernard Verrier. (2020) Tailoring mRNA Vaccine to Balance Innate/Adaptive Immune Response. Trends in Molecular Medicine 26:3, pages 311-323.
Crossref
Itziar Gómez-Aguado, Julen Rodríguez-Castejón, Mónica Vicente-Pascual, Alicia Rodríguez-Gascón, María Ángeles Solinís & Ana del Pozo-Rodríguez. (2020) Nanomedicines to Deliver mRNA: State of the Art and Future Perspectives. Nanomaterials 10:2, pages 364.
Crossref
Muhammad Imran Qadir, Sherien Bukhat, Sumaira Rasul, Hamid Manzoor & Majid Manzoor. (2019) RNA therapeutics: Identification of novel targets leading to drug discovery. Journal of Cellular Biochemistry 121:2, pages 898-929.
Crossref
Androulla N. Miliotou & Lefkothea C. Papadopoulou. 2020. Chimeric Antigen Receptor T Cells. Chimeric Antigen Receptor T Cells 87 117 .
Ramachandra Naik & Keith Peden. 2022. mRNA Vaccines. mRNA Vaccines 187 205 .
Brett W Jagger, Kimberly A Dowd, Rita E Chen, Pritesh Desai, Bryant Foreman, Katherine E Burgomaster, Sunny Himansu, Wing-Pui Kong, Barney S Graham, Theodore C Pierson & Michael S Diamond. (2019) Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice. The Journal of Infectious Diseases 220:10, pages 1577-1588.
Crossref
Cristina Poveda, Amadeo B. Biter, Maria Elena Bottazzi & Ulrich Strych. (2019) Establishing Preferred Product Characterization for the Evaluation of RNA Vaccine Antigens. Vaccines 7:4, pages 131.
Crossref
Alvin J. Mukalel, Rachel S. Riley, Rui Zhang & Michael J. Mitchell. (2019) Nanoparticles for nucleic acid delivery: Applications in cancer immunotherapy. Cancer Letters 458, pages 102-112.
Crossref
A. A. Goryaev, M. V. Savkina, Yu. I. Obukhov, V. A. Merkulov & Yu. V. Olefir. (2019) DNA and RNA Vaccines: Current Status, Quality Requirements and Specific Aspects of Preclinical Studies. BIOpreparations. Prevention, Diagnosis, Treatment 19:2, pages 72-80.
Crossref
Zeljka Trepotec, Johannes Geiger, Christian Plank, Manish K. Aneja & Carsten Rudolph. (2019) Segmented poly(A) tails significantly reduce recombination of plasmid DNA without affecting mRNA translation efficiency or half-life. RNA 25:4, pages 507-518.
Crossref
Zeljka Trepotec, Eva Lichtenegger, Christian Plank, Manish K. Aneja & Carsten Rudolph. (2019) Delivery of mRNA Therapeutics for the Treatment of Hepatic Diseases. Molecular Therapy 27:4, pages 794-802.
Crossref
Chengxiang Zhang, Xinfu Zhang, Weiyu Zhao, Chunxi Zeng, Wenqing Li, Bin Li, Xiao Luo, Junan Li, Justin Jiang, Binbin Deng, David W. McComb & Yizhou Dong. (2019) Chemotherapy drugs derived nanoparticles encapsulating mRNA encoding tumor suppressor proteins to treat triple-negative breast cancer. Nano Research 12:4, pages 855-861.
Crossref
Cuiling Zhang, Giulietta Maruggi, Hu Shan & Junwei Li. (2019) Advances in mRNA Vaccines for Infectious Diseases. Frontiers in Immunology 10.
Crossref
Bin Li, Xinfu Zhang & Yizhou Dong. (2018) Nanoscale platforms for messenger RNA delivery. WIREs Nanomedicine and Nanobiotechnology 11:2.
Crossref
Zeljka TrepotecManish K. AnejaJohannes GeigerGuenther HasenpuschChristian PlankCarsten Rudolph. (2019) Maximizing the Translational Yield of mRNA Therapeutics by Minimizing 5′-UTRs. Tissue Engineering Part A 25:1-2, pages 69-79.
Crossref
Yuhang Jiang, Alice Gaudin, Junwei Zhang, Tushar Agarwal, Eric Song, Amy C. Kauffman, Gregory T. Tietjen, Yongheng Wang, Zhaozhong Jiang, Christopher J. Cheng & W. Mark Saltzman. (2018) A “top-down” approach to actuate poly(amine-co-ester) terpolymers for potent and safe mRNA delivery. Biomaterials 176, pages 122-130.
Crossref
J Magarian Blander & Gaetan Barbet. (2018) Exploiting vita-PAMPs in vaccines. Current Opinion in Pharmacology 41, pages 128-136.
Crossref
Christian Gampe, Amy C. Seila White, Swetha Siva, Frédéric Zécri & John Diener. (2018) 3′-Modification stabilizes mRNA and increases translation in cells. Bioorganic & Medicinal Chemistry Letters 28:14, pages 2451-2453.
Crossref
Glenn D. Bell, Yi Yang, Euphemia Leung & Geoffrey W. Krissansen. (2018) mRNA transfection by a Xentry-protamine cell-penetrating peptide is enhanced by TLR antagonist E6446. PLOS ONE 13:7, pages e0201464.
Crossref
Clay PattonGist H. FarrIIIIIIDing AnPaolo G.V. MartiniLisa Maves. (2018) Lipid Nanoparticle Packaging Is an Effective and Nontoxic mRNA Delivery Platform in Embryonic Zebrafish. Zebrafish 15:3, pages 217-227.
Crossref
Azizul Haque, Faruk Berat Akçeşme & Anudeep B Pant. (2017) A Review of Zika Virus: Hurdles toward Vaccine Development and the Way Forward. Antiviral Therapy 23:4, pages 285-293.
Crossref
Norbert Pardi, Michael J. Hogan, Frederick W. Porter & Drew Weissman. (2018) mRNA vaccines — a new era in vaccinology. Nature Reviews Drug Discovery 17:4, pages 261-279.
Crossref
Mary G. Prieve, Pierrot Harvie, Sean D. Monahan, Debashish Roy, Allen G. Li, Teri L. Blevins, Amber E. Paschal, Matt Waldheim, Eric C. Bell, Anna Galperin, Jean-Rene Ella-Menye & Michael E. Houston. (2018) Targeted mRNA Therapy for Ornithine Transcarbamylase Deficiency. Molecular Therapy 26:3, pages 801-813.
Crossref
Shinu John, Olga Yuzhakov, Angela Woods, Jessica Deterling, Kimberly Hassett, Christine A. Shaw & Giuseppe Ciaramella. (2018) Multi-antigenic human cytomegalovirus mRNA vaccines that elicit potent humoral and cell-mediated immunity. Vaccine 36:12, pages 1689-1699.
Crossref
Ameer Khusro, Chirom Aarti, Alberto Barbabosa-Pilego & Pedro Sánchez-Aparicio. (2018) Outbreak of Zika virus pathogenesis and quest of its vaccine development: Where do we stand now?. Microbial Pathogenesis 116, pages 289-295.
Crossref
Kaitlyn M Morabito & Barney S Graham. (2017) Zika Virus Vaccine Development. The Journal of Infectious Diseases 216:suppl_10, pages S957-S963.
Crossref
Yunfeng Yan, Hu Xiong, Xinyi Zhang, Qiang Cheng & Daniel J. Siegwart. (2017) Systemic mRNA Delivery to the Lungs by Functional Polyester-based Carriers. Biomacromolecules 18:12, pages 4307-4315.
Crossref
Yang Liu, Manoj N. Krishnan & Kyle K.L. Phua. (2017) Suppression of mRNA Nanoparticle Transfection in Human Fibroblasts by Selected Interferon Inhibiting Small Molecule Compounds. Biomolecules 7:4, pages 56.
Crossref
Norbert Pardi, Anthony J. Secreto, Xiaochuan Shan, Fotini Debonera, Joshua Glover, Yanjie Yi, Hiromi Muramatsu, Houping Ni, Barbara L. Mui, Ying K. Tam, Farida Shaheen, Ronald G. Collman, Katalin Karikó, Gwenn A. Danet-Desnoyers, Thomas D. Madden, Michael J. Hope & Drew Weissman. (2017) Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge. Nature Communications 8:1.
Crossref
Norbert Pardi, Michael J. Hogan, Rebecca S. Pelc, Hiromi Muramatsu, Hanne Andersen, Christina R. DeMaso, Kimberly A. Dowd, Laura L. Sutherland, Richard M. Scearce, Robert Parks, Wendeline Wagner, Alex Granados, Jack Greenhouse, Michelle Walker, Elinor Willis, Jae-Sung Yu, Charles E. McGee, Gregory D. Sempowski, Barbara L. Mui, Ying K. Tam, Yan-Jang Huang, Dana Vanlandingham, Veronica M. Holmes, Harikrishnan Balachandran, Sujata Sahu, Michelle Lifton, Stephen Higgs, Scott E. Hensley, Thomas D. Madden, Michael J. Hope, Katalin Karikó, Sampa Santra, Barney S. Graham, Mark G. Lewis, Theodore C. Pierson, Barton F. Haynes & Drew Weissman. (2017) Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination. Nature 543:7644, pages 248-251.
Crossref
David B. Rozema. 2017. Platform Technologies in Drug Discovery and Validation. Platform Technologies in Drug Discovery and Validation 17 59 .
Kevin J. Kauffman, Faryal F. Mir, Siddharth Jhunjhunwala, James C. Kaczmarek, Juan E. Hurtado, Jung H. Yang, Matthew J. Webber, Piotr S. Kowalski, Michael W. Heartlein, Frank DeRosa & Daniel G. Anderson. (2016) Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo. Biomaterials 109, pages 78-87.
Crossref
Kevin J. Kauffman, Matthew J. Webber & Daniel G. Anderson. (2016) Materials for non-viral intracellular delivery of messenger RNA therapeutics. Journal of Controlled Release 240, pages 227-234.
Crossref
Jeffrey B Ulmer & Andrew J Geall. (2016) Recent innovations in mRNA vaccines. Current Opinion in Immunology 41, pages 18-22.
Crossref
Yu Liu, Rui Sousa & Yun-Xing Wang. (2016) Specific labeling: An effective tool to explore the RNA world. BioEssays 38:2, pages 192-200.
Crossref
Robert E. Rhoads. 2016. Synthetic mRNA. Synthetic mRNA 3 27 .
Norbert Pardi, Steven Tuyishime, Hiromi Muramatsu, Katalin Kariko, Barbara L. Mui, Ying K. Tam, Thomas D. Madden, Michael J. Hope & Drew Weissman. (2015) Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes. Journal of Controlled Release 217, pages 345-351.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.