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The importance of TSLP in allergic disease and its role as a potential therapeutic target

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Yu-qing Hu & Jian-zhong Zhang. (2022) A Comparison for Type 2 Cytokines and Lesional Inflammatory Infiltrations in Bullous Pemphigoid and Atopic Dermatitis. Clinical, Cosmetic and Investigational Dermatology 15, pages 2313-2321.
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Dina Leth Møller, Katrine Kielsen, Claus Henrik Nielsen, Henrik Sengeløv, Anders Elm Pedersen, Lars Peter Ryder & Klaus Müller. (2022) Thymic stromal lymphopoietin levels after allogeneic hematopoietic stem cell transplantation. Immunopharmacology and Immunotoxicology 44:6, pages 1004-1012.
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Giuseppe Ingrasci, Zoe M. Lipman & Gil Yosipovitch. (2021) When topical therapy of atopic dermatitis fails: a guide for the clinician. Expert Review of Clinical Immunology 17:12, pages 1245-1256.
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Kam Lun Hon, Steven Loo, Alexander K. C. Leung, Joyce T. S. Li & Vivian W. Y. Lee. (2020) An overview of drug discovery efforts for eczema: why is this itch so difficult to scratch?. Expert Opinion on Drug Discovery 15:4, pages 487-498.
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Liang-Ming Cai, Yu-Qi Zhou, Li-Fen Yang, Jing-Xin Qu, Zhen-Yuan Dai, Hong-Tao Li, Li Pan, Hui-Qing Ye & Zhuang-Gui Chen. (2019) Thymic stromal lymphopoietin induced early stage of epithelial-mesenchymal transition in human bronchial epithelial cells through upregulation of transforming growth factor beta 1. Experimental Lung Research 45:8, pages 221-235.
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Ángel Arias & Alfredo J. Lucendo. (2019) Molecular basis and cellular mechanisms of eosinophilic esophagitis for the clinical practice. Expert Review of Gastroenterology & Hepatology 13:2, pages 99-117.
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Melanie A Ruffner, Katie Kennedy & Antonella Cianferoni. (2019) Pathophysiology of eosinophilic esophagitis: recent advances and their clinical implications. Expert Review of Clinical Immunology 15:1, pages 83-95.
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Hillary L. Shane, Carrie M. Long & Stacey E. Anderson. (2019) Novel cutaneous mediators of chemical allergy. Journal of Immunotoxicology 16:1, pages 13-27.
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Na-Ra Han, Phil-Dong Moon, Hyung-Min Kim & Hyun-Ja Jeong. (2018) Cordycepin ameliorates skin inflammation in a DNFB-challenged murine model of atopic dermatitis. Immunopharmacology and Immunotoxicology 40:5, pages 401-407.
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Hong-tao Li, Zhuang-gui Chen, Hui Liu, Jin Ye, Xiao-ling Zou, Yan-hong Wang, Hai-ling Yang, Ping Meng & Tian-tuo Zhang. (2016) Treatment of allergic rhinitis with CpG oligodeoxynucleotides alleviates the lower airway outcomes of combined allergic rhinitis and asthma syndrome via a mechanism that possibly involves in TSLP. Experimental Lung Research 42:6, pages 322-333.
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Articles from other publishers (129)

Honglin Qu, Xinning Liu, Ting Jiang, Guodong Huang, Houhao Cai, Daijun Xing, Yuecheng Mao & Xin Zheng. (2023) Integration analysis using bioinformatics and experimental validation on the clinical and biological significance of TSLP in cancers. Cellular Signalling 111, pages 110874.
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Andreas Frey, Lars P. Lunding & Michael Wegmann. (2023) The Dual Role of the Airway Epithelium in Asthma: Active Barrier and Regulator of Inflammation. Cells 12:18, pages 2208.
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Decai Wang, Fan Wang, Yu Huang, Jianjun Wang, Huiwen Luo, Pu Zhang, Jingtao Peng, Gang Tang, Yaodong Wang, Li Yu & Dong Ni. (2023) TSLP/TSLPR promotes renal fibrosis by activating STAT3 in renal fibroblasts. International Immunopharmacology 121, pages 110430.
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Hye-Jeong Jang, Jung Bok Lee & Jeong-Kee Yoon. (2023) Advanced In Vitro Three-Dimensional Skin Models of Atopic Dermatitis. Tissue Engineering and Regenerative Medicine 20:4, pages 539-552.
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Shan Wang, Bowen Liu, Jiahao Huang, Huiru He, Linghui Zhou, Ying He, Jie Yan & Ailin Tao. (2023) Succinate and mitochondrial DNA trigger atopic march from atopic dermatitis to intestinal inflammation. Journal of Allergy and Clinical Immunology 151:4, pages 1050-1066.e7.
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Lanyan Fu, Daniel Thomas MacKeigan, Qing Gong, Di Che, Yufen Xu, Lei Pi, Chaonan Sun, Hongyan Yu, Kaining Chen, Huazhong Zhou, Zhiyong Jiang, Zhouping Wang, Li Zhang, Eric G. Cerenzia, Heyu Ni & Xiaoqiong Gu. (2022) Thymic stromal lymphopoietin induces platelet mitophagy and promotes thrombosis in Kawasaki disease. British Journal of Haematology 200:6, pages 776-791.
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Wieneke Dijk, Caterina Villa, Sara Benedé, Emilia Vassilopoulou, Isabel Mafra, María Garrido‐Arandia, Mónica Martínez Blanco, Gregory Bouchaud, Tamara Hoppenbrouwers, Simona Lucia Bavaro, Linda Giblin, Karen Knipping, Ana Maria Castro, Susana Delgado, Joana Costa & Shanna Bastiaan‐Net. (2022) Critical features of an in vitro intestinal absorption model to study the first key aspects underlying food allergen sensitization. Comprehensive Reviews in Food Science and Food Safety 22:2, pages 971-1005.
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Jerome Kaikati, Reine Merhy, Anne-sophie Sarkis & Roland Tomb. (2023) Secukinumab: A life-changing treatment for Netherton syndrome?. Annales de Dermatologie et de Vénéréologie 150:1, pages 61-63.
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Elena Grueso-Navarro, Pilar Navarro, Emilio J. Laserna-Mendieta, Alfredo J. Lucendo & Laura Arias-González. (2023) Blood-Based Biomarkers for Eosinophilic Esophagitis and Concomitant Atopic Diseases: A Look into the Potential of Extracellular Vesicles. International Journal of Molecular Sciences 24:4, pages 3669.
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Ji Hye Yoon, Mi-Yeon Kim & Jae Youl Cho. (2023) Apigenin: A Therapeutic Agent for Treatment of Skin Inflammatory Diseases and Cancer. International Journal of Molecular Sciences 24:2, pages 1498.
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Ping Miao, Yiming Jiang, Ying Jian, Jiali Shi, Yao Liu, Pipat Piewngam, Yue Zheng, Gordon Y. C. Cheung, Qian Liu, Michael Otto & Min Li. (2023) Exacerbation of allergic rhinitis by the commensal bacterium Streptococcus salivarius. Nature Microbiology 8:2, pages 218-230.
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Kristina Mäemets-Allas, Mariliis Klaas, Claudia Griselda Cárdenas-León, Terje Arak, Esko Kankuri & Viljar Jaks. (2023) Stimulation with THBS4 activates pathways that regulate proliferation, migration and inflammation in primary human keratinocytes. Biochemical and Biophysical Research Communications 642, pages 97-106.
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David Grand, John W. Frew & Jason E. Hawkes. 2023. Atopic Dermatitis : Inside Out Or Outside in. Atopic Dermatitis : Inside Out Or Outside in 168 178 .
Alison G. Stanbery, Shuchi Smita, Jakob von Moltke, Elia D. Tait Wojno & Steven F. Ziegler. (2022) TSLP, IL-33, and IL-25: Not just for allergy and helminth infection. Journal of Allergy and Clinical Immunology 150:6, pages 1302-1313.
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Zhaoheng Wang, Jiangdong An, Daxue Zhu, Haiwei Chen, Aixin Lin, Jihe Kang, Wenzhao Liu & Xuewen Kang. (2022) Periostin: an emerging activator of multiple signaling pathways. Journal of Cell Communication and Signaling 16:4, pages 515-530.
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V. Dytiatkovskyi. (2022) Variants of the single nucleotide polymorphisms of thymic stromal lymphopoietin and orsomucoid-1-like protein 3 as predictors of the mono- and polyorganic clinical phenotypes of atopic disorders in children. CHILD`S HEALTH 17:6, pages 276-281.
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Nang-Kyu Kim, Sung-Hoon Kim, Bo-Hyeon Park & Eun-Ju Choi. (2022) Human Epidermal Growth Factor Improves Atopic Disease-like Skin Lesions in DFE/DNCB Induced BALB/c Mice and Human Keratinocytes. Exercise Science 31:4, pages 537-544.
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Xuefeng Xu, Huaping Dai & Jinglan Zhang. (2022) The potential role of interleukin (IL)‐25/IL‐33/thymic stromal lymphopoietin (TSLP) on the pathogenesis of idiopathic pulmonary fibrosis. The Clinical Respiratory Journal 16:11, pages 696-707.
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Wael Alturaiki. (2022) High plasma levels of the TSLP cytokine in Saudi patients with chronic stable asthma. Journal of King Saud University - Science 34:7, pages 102271.
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Elizabeth Chorvinsky, Gustavo Nino, Kyle Salka, Susana Gaviria, Maria J. Gutierrez & Dinesh K. Pillai. (2022) TSLP bronchoalveolar lavage levels at baseline are linked to clinical disease severity and reduced lung function in children with asthma. Frontiers in Pediatrics 10.
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Wenchuan Chang, Hao Lv, Lu Tan, Ziang Gao, Peiqiang Liu, Danxue Qin, Wei Zhang & Yu Xu. (2022) Downregulation of deubiquitinating enzyme USP25 promotes the development of allergic rhinitis by enhancing TSLP signaling in the nasal epithelium. Molecular Medicine Reports 26:5.
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Hwa Pyoung Lee, Wooram Choi, Ki Woong Kwon, Long You, Laily Rahmawati, Van Dung Luong, Wonhee Kim, Byoung-Hee Lee, Sarah Lee, Ji Hye Kim & Jae Youl Cho. (2022) Inhibitory Effects of Grewia tomentosa Juss. on IgE-Mediated Allergic Reaction and DNCB-Induced Atopic Dermatitis. Plants 11:19, pages 2540.
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T. Bieber, A.S. Paller, K. Kabashima, M. Feely, M.J. Rueda, J.A. Ross Terres & A. Wollenberg. (2022) Atopic dermatitis: pathomechanisms and lessons learned from novel systemic therapeutic options. Journal of the European Academy of Dermatology and Venereology 36:9, pages 1432-1449.
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Babina Sanjel & Won-Sik Shim. (2022) The contribution of mouse models to understanding atopic dermatitis. Biochemical Pharmacology 203, pages 115177.
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Jae Won Lee & Ee Taek Hwang. (2022) Oral administration of tetrahydrocurcumin entrapped hybrid colloid as a food additive ameliorates atopic dermatitis. Journal of Functional Foods 90, pages 104972.
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Luca Fania, Gaia Moretta, Flaminia Antonelli, Enrico Scala, Damiano Abeni, Cristina Albanesi & Stefania Madonna. (2022) Multiple Roles for Cytokines in Atopic Dermatitis: From Pathogenic Mediators to Endotype-Specific Biomarkers to Therapeutic Targets. International Journal of Molecular Sciences 23:5, pages 2684.
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Nyoman Suryawati, Made Wardhana, IMade Bakta & Made Jawi. (2022) Moisturizing nanoemulgel of turmeric (Curcuma longa) rhizome extract ameliorates atopic dermatitis-like skin lesions in mice model through thymic stromal lymphopoietin, interleukin-13, and interleukin-17. Biomolecular and Health Science Journal 5:2, pages 81.
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Yiang Yu, Jingxin Li & Chuanyong Liu. (2022) Oxytocin suppresses epithelial cell-derived cytokines production and alleviates intestinal inflammation in food allergy. Biochemical Pharmacology 195, pages 114867.
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Rebecca L. Watkinson, Kevin Looi, Ingrid A. Laing, Antonella Cianferoni & Anthony Kicic. (2021) Viral Induced Effects on a Vulnerable Epithelium; Lessons Learned From Paediatric Asthma and Eosinophilic Oesophagitis. Frontiers in Immunology 12.
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Weiwei Wang, Hongwei Yu, Yongliang Pan & Shengwen Shao. (2021) Combined Treatment With H1 and H4 Receptor Antagonists Improves Th2 Inflammatory Responses in the Nasal Mucosa of Allergic Rhinitis Rats. American Journal of Rhinology & Allergy 35:6, pages 809-816.
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C. Moermans, K. Damas, J. Guiot, M.S. Njock, J.L. Corhay, M. Henket, F. Schleich & R. Louis. (2021) Sputum IL-25, IL-33 and TSLP, IL-23 and IL-36 in airway obstructive diseases. Reduced levels of IL-36 in eosinophilic phenotype. Cytokine 140, pages 155421.
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Jae Ho Choi, Gi Ho Lee, Sun Woo Jin, Ji Yeon Kim, Yong Pil Hwang, Eun Hee Han, Young Ho Kim & Hye Gwang Jeong. (2021) Impressic Acid Ameliorates Atopic Dermatitis-Like Skin Lesions by Inhibiting ERK1/2-Mediated Phosphorylation of NF-κB and STAT1. International Journal of Molecular Sciences 22:5, pages 2334.
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Seung-Heon Shin, Mi-Kyung Ye, Mi-Hyun Chae & Dong-Won Lee. (2021) <i>Chamaecyparis obtusa</i> Essential Oil Inhibits House Dust Mite Induced Nasal Epithelial Cell Activation and Immune Responses. Journal of Oleo Science 70:3, pages 431-438.
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Partho Protim Adhikary, Zheng Tan, Brent D.G. Page & Sarah Hedtrich. (2021) TSLP as druggable target – a silver-lining for atopic diseases?. Pharmacology & Therapeutics 217, pages 107648.
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Noo Ri Lee, Beom Jun Kim, Chung Hyeok Lee, Young Bin Lee, Solam Lee, Hyun Jee Hwang, Eunjung Kim, Sung Hee Kim, Min-Geol Lee, Sang Eun Lee, Gareth G. Lavery & Eung Ho Choi. (2020) Role of 11β-hydroxysteroid dehydrogenase type 1 in the development of atopic dermatitis. Scientific Reports 10:1.
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