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Original Research

Amorphous silica nanoparticles trigger nitric oxide/peroxynitrite imbalance in human endothelial cells: inflammatory and cytotoxic effects

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Pages 2821-2835 | Published online: 09 Nov 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (17)

Xuemeng Dong, Zehao Wu, Xiuping Li, Liyan Xiao, Man Yang, Yang Li, Junchao Duan & Zhiwei Sun. (2020) The Size-dependent Cytotoxicity of Amorphous Silica Nanoparticles: A Systematic Review of in vitro Studies. International Journal of Nanomedicine 15, pages 9089-9113.
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Mansour Almansour, Saud Alarifi & Bashir Jarrar. (2018) In vivo investigation on the chronic hepatotoxicity induced by intraperitoneal administration of 10-nm silicon dioxide nanoparticles. International Journal of Nanomedicine 13, pages 2685-2696.
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Magdalena Kusaczuk, Rafał Krętowski, Monika Naumowicz, Anna Stypułkowska & Marzanna Cechowska-Pasko. (2018) Silica nanoparticle-induced oxidative stress and mitochondrial damage is followed by activation of intrinsic apoptosis pathway in glioblastoma cells. International Journal of Nanomedicine 13, pages 2279-2294.
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W. Kyle Mandler, Timothy R. Nurkiewicz, Dale W. Porter & I. Mark Olfert. (2017) Thrombospondin-1 mediates multi-walled carbon nanotube induced impairment of arteriolar dilation. Nanotoxicology 11:1, pages 112-122.
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Abderrahim Nemmar, Priya Yuvaraju, Sumaya Beegam, Javed Yasin, Elsadig E Kazzam & Badreldin H Ali. (2016) Oxidative stress, inflammation, and DNA damage in multiple organs of mice acutely exposed to amorphous silica nanoparticles. International Journal of Nanomedicine 11, pages 919-928.
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James Clark, Clive C. Gregory, Ian P. Matthews & Bastiaan Hoogendoorn. (2016) The biological effects upon the cardiovascular system consequent to exposure to particulates of less than 500 nm in size. Biomarkers 21:1, pages 1-47.
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Caixia Guo, Yinye Xia, Piye Niu, Lizhen Jiang, Junchao Duan, Yang Yu, Xianqing Zhou, Yanbo Li & Zhiwei Sun. (2015) Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling. International Journal of Nanomedicine 10, pages 1463-1477.
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Désirée White-Schenk, Riyi Shi & James F Leary. (2015) Nanomedicine strategies for treatment of secondary spinal cord injury. International Journal of Nanomedicine 10, pages 923-938.
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Sylvie Poussard, Marion Decossas, Olivier Le Bihan, Stéphane Mornet, Grégoire Naudin & Olivier Lambert. (2015) Internalization and fate of silica nanoparticles in C2C12 skeletal muscle cells: evidence of a beneficial effect on myoblast fusion. International Journal of Nanomedicine 10, pages 1479-1492.
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Junchao Duan, Yongbo Yu, Yang Yu, Yang Li, Ji Wang, Weijia Geng, Lizhen Jiang, Qiuling Li, Xianqing Zhou & Zhiwei Sun. (2014) Silica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway. International Journal of Nanomedicine 9, pages 5131-5141.
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Abderrahim Nemmar, Sulayma Albarwani, Sumaya Beegam, Priya Yuvaraju, Javed Yasin, Samir Attoub & Badreldin H Ali. (2014) Amorphous silica nanoparticles impair vascular homeostasis and induce systemic inflammation. International Journal of Nanomedicine 9, pages 2779-2789.
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Jung-Eun Kim, Hyejin Kim, Seong Soo A An, Eun Ho Maeng, Meyoung-Kon Kim & Yoon-Jae Song. (2014) In vitro cytotoxicity of SiO2 or ZnO nanoparticles with different sizes and surface charges on U373MG human glioblastoma cells. International Journal of Nanomedicine 9:sup2, pages 235-241.
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Trisha Eustaquio & James F Leary. (2012) Nanobarcoding: detecting nanoparticles in biological samples using in situ polymerase chain reaction. International Journal of Nanomedicine 7, pages 5625-5639.
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Maneerat Ekkapongpisit, Antonino Giovia, Carlo Follo, Giuseppe Caputo & Ciro Isidoro. (2012) Biocompatibility, endocytosis, and intracellular trafficking of mesoporous silica and polystyrene nanoparticles in ovarian cancer cells: effects of size and surface charge groups. International Journal of Nanomedicine 7, pages 4147-4158.
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Maneerat Ekkapongpisit, Antonino Giovia, Giuseppina Nicotra, Matteo Ozzano, Giuseppe Caputo & Ciro Isidoro. (2012) Labeling and exocytosis of secretory compartments in RBL mastocytes by polystyrene and mesoporous silica nanoparticles. International Journal of Nanomedicine 7, pages 1829-1840.
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J Jose Corbalan, Carlos Medina, Adam Jacoby, Tadeusz Malinski & Marek W Radomski. (2012) Amorphous silica nanoparticles aggregate human platelets: potential implications for vascular homeostasis. International Journal of Nanomedicine 7, pages 631-639.
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Xiuyan Wan, Xinhao Zhang, Wei Pan, Bo Liu, Longhai Yu, Honghong Wang, Na Li & Bo Tang. (2019) Ratiometric Fluorescent Quantification of the Size-Dependent Cellular Toxicity of Silica Nanoparticles. Analytical Chemistry 91:9, pages 6088-6096.
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Jiban Saikia, Raziye Mohammadpour, Mostafa Yazdimamaghani, Hannah Northrup, Vladimir Hlady & Hamidreza Ghandehari. (2018) Silica Nanoparticle–Endothelial Interaction: Uptake and Effect on Platelet Adhesion under Flow Conditions. ACS Applied Bio Materials 1:5, pages 1620-1627.
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Ilhwan Park, Tra Nguyen, Jinsoo Park, Ah Young Yoo, Jae Kweon Park & Sungbo Cho. (2018) Impedance Characterization of Chitosan Cytotoxicity to MCF-7 Breast Cancer Cells Using a Multidisc Indium Tin Oxide Microelectrode Array. Journal of The Electrochemical Society 165:2, pages B55-B59.
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Sivakumar Murugadoss, Dominique Lison, Lode Godderis, Sybille Van Den Brule, Jan Mast, Frederic Brassinne, Noham Sebaihi & Peter H. Hoet. (2017) Toxicology of silica nanoparticles: an update. Archives of Toxicology 91:9, pages 2967-3010.
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