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International Journal of Hyperthermia Volume 27, 2011 - Issue 6
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Research Article

Radiofrequency ablation combined with liposomal quercetin to increase tumour destruction by modulation of heat shock protein production in a small animal model

Wei YangMinimally Invasive Tumor Therapies Laboratory, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA;Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Ultrasound, Peking University Cancer Hospital and Institute, Beijing, China
,
Muneeb AhmedMinimally Invasive Tumor Therapies Laboratory, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USACorrespondence[email protected]
, MD,
Beenish TasawwarMinimally Invasive Tumor Therapies Laboratory, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA
,
Tatyana LevchenkoDepartment of Pharmaceutical Sciences and Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, MA, USA
,
Rupa R. SawantDepartment of Pharmaceutical Sciences and Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, MA, USA
,
Michael CollinsDepartment of Radiation Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
,
Sabina SignorettiDepartment of Radiation Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
,
Vladimir TorchilinDepartment of Pharmaceutical Sciences and Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, MA, USA
&
S. Nahum GoldbergMinimally Invasive Tumor Therapies Laboratory, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA;Division of Image-guided Therapy, Department of Radiology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
 show all
Pages 527-538 | Received 25 Oct 2010, Accepted 14 Apr 2011, Published online: 16 Aug 2011

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Hao Li, Pengfei Chen, Manzhou Wang, Wenhui Wang, Fangzheng Li, Xinwei Han, Jianzhuang Ren & Xuhua Duan. (2022) Liposome quercetin enhances the ablation effects of microwave ablation in treating the rabbit VX2 liver tumor model. International Journal of Hyperthermia 39:1, pages 162-172.
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Aurelia Markezana, S. Nahum Goldberg, Gaurav Kumar, Elina Zorde-Khvalevsky, Svetlana Gourevtich, Nir Rozenblum, Eithan Galun & Muneeb Ahmed. (2021) Incomplete thermal ablation of tumors promotes increased tumorigenesis. International Journal of Hyperthermia 38:1, pages 263-272.
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Aurelia Markezana, Muneeb Ahmed, Gaurav Kumar, Elina Zorde-Khvalevsky, Nir Rozenblum, Eithan Galun & S. Nahum Goldberg. (2020) Moderate hyperthermic heating encountered during thermal ablation increases tumor cell activity. International Journal of Hyperthermia 37:1, pages 119-129.
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Pengcheng Xu, Haisheng Wang, Hongxiang Hu, Yong Ye, Yu Dong, Suxin Li, Dong Mei, Zhaoming Guo, Dan Wang, Yanxue Sun, Tengfei Yu, Junchan Qiao & Qiang Zhang. (2019) cRGDfK-Grafted Small-Size Quercetin Micelles For Enhancing Therapy Efficacy Of Active Ingredient From The Chinese Medicinal Herb. International Journal of Nanomedicine 14, pages 9173-9184.
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Fen Chen, Haiwei Bao, Haiyang Xie, Guo Tian & Tianan Jiang. (2019) Heat shock protein expression and autophagy after incomplete thermal ablation and their correlation. International Journal of Hyperthermia 36:1, pages 95-103.
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Muneeb Ahmed, Gaurav Kumar, Svetlana Gourevitch, Tatyana Levchenko, Eithan Galun, Vladimir Torchilin & S. Nahum Goldberg. (2018) Radiofrequency ablation (RFA)-induced systemic tumor growth can be reduced by suppression of resultant heat shock proteins. International Journal of Hyperthermia 34:7, pages 934-942.
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Marwan Moussa, S. Nahum Goldberg, Gaurav Kumar, Tatyana Levchenko, Vladimir Torchilin & Muneeb Ahmed. (2016) Effect of thermal dose on heat shock protein expression after radio-frequency ablation with and without adjuvant nanoparticle chemotherapies. International Journal of Hyperthermia 32:8, pages 829-841.
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Beth Goins, William T. Phillips & Ande Bao. (2016) Strategies for improving the intratumoral distribution of liposomal drugs in cancer therapy. Expert Opinion on Drug Delivery 13:6, pages 873-889.
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Yizhe Chen, Pilju Youn, Theodore J. Pysher, Courtney L. Scaife & Darin Y. Furgeson. (2014) Tumour eradication using synchronous thermal ablation and Hsp90 chemotherapy with protein engineered triblock biopolymer-geldanamycin conjugates. International Journal of Hyperthermia 30:8, pages 550-564.
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Nina M. Muñoz, Crystal Dupuis, Malea Williams, Katherine Dixon, Amanda McWatters, Rony Avritscher, Richard Bouchard, Ahmed Kaseb, Kyle M. Schachtschneider, Arvind Rao & Rahul A. Sheth. (2020) Molecularly targeted photothermal ablation improves tumor specificity and immune modulation in a rat model of hepatocellular carcinoma. Communications Biology 3:1.
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Sabya S. Das, Afzal Hussain, Priya R. Prasad Verma, Syed S. Imam, Mohammad A. Altamimi, Sultan Alshehri & Sandeep Kumar Singh. (2020) Recent Advances in Liposomal Drug Delivery System of Quercetin for Cancer Targeting: A Mechanistic Approach. Current Drug Delivery 17:10, pages 845-860.
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Hong‐yan Zhai, Qun‐fang Zhou, Jian‐ping Dou, Fang‐yi Liu, Xin‐yuan Zhu, Jie Yu & Ping Liang. (2019) Hepatic Microwave Ablation–Induced Tumor Destruction and Animal End Point Survival Can Be Improved by Suppression of Heat Shock Protein 90. Journal of Ultrasound in Medicine 39:6, pages 1223-1232.
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Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta & Shusen Zheng. (2020) Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation. Molecular Medicine Reports.
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