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Research Article

Melan-A specific CD8+ T lymphocytes after hyperthermic isolated limb perfusion: A pilot study in patients with in-transit metastases of malignant melanoma

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Pages 234-238 | Received 10 Dec 2012, Accepted 28 Feb 2013, Published online: 16 Apr 2013

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Junko Johansson, Roberta Kiffin, Ebru Aydin, Malin S. Nilsson, Kristoffer Hellstrand, Per Lindnér, Peter Naredi, Roger Olofsson Bagge & Anna Martner. (2020) Isolated limb perfusion with melphalan activates interferon-stimulated genes to induce tumor regression in patients with melanoma in-transit metastasis. OncoImmunology 9:1.
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Francesco Fiz, Giuseppe Villa, Enrico Ferrari, Elena Pomposelli, Silvia Morbelli, Antonella Alloisio, Daniela Pende, Raffaella Meazza, Cristina Gereloni, Cecilia Marini, Giovanni Battista Ratto & Gianmario Sambuceti. (2018) Prevention of systemic toxicity in hyperthermic isolated lung perfusion using radioisotopic leakage monitoring. International Journal of Hyperthermia 34:4, pages 469-478.
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Roger Olofsson Bagge, Jan Mattsson & Lo Hafström. (2014) Regional hyperthermic perfusion with melphalan after surgery for recurrent malignant melanoma of the extremities – Long-term follow-up of a randomised trial. International Journal of Hyperthermia 30:5, pages 295-298.
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Roger Olofsson, Jan Mattsson & Per Lindnér. (2013) Long-term follow-up of 163 consecutive patients treated with isolated limb perfusion for in-transit metastases of malignant melanoma. International Journal of Hyperthermia 29:6, pages 551-557.
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Articles from other publishers (14)

Sungyun Kim, Jae-Hee Ahn, Da In Jeong, Mingyu Yang, Jae-Hyeon Jeong, Yeoung Eun Choi, Hyun Jin Kim, Youngjoo Han, Mrinmoy Karmakar, Hyun-Jeong Ko & Hyun-Jong Cho. (2023) Alum-tuned hyaluronic acid-based hydrogel with immune checkpoint inhibition for immunophoto therapy of cancer. Journal of Controlled Release 362, pages 1-18.
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Carl-Jacob Holmberg, Jan Mattsson & Roger Olofsson Bagge. (2023) Effects of the Introduction of Modern Immunotherapy on the Outcome of Isolated Limb Perfusion for Melanoma In-Transit Metastases. Cancers 15:2, pages 472.
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Carl-Jacob Holmberg, Lars Ny, Tina J. Hieken, Matthew S. Block, Michael J. Carr, Vernon K. Sondak, Christoffer Örtenwall, Dimitrios Katsarelias, Florentia Dimitriou, Alexander M. Menzies, Robyn PM. Saw, Aljosja Rogiers, Richard J. StrakerIIIIII, Giorgos Karakousis, Rona Applewaite, Lalit Pallan, Dale Han, John T. Vetto, David E. Gyorki, Emilia Nan Tie, Maria Grazia Vitale, Paulo A. Ascierto, Reinhard Dummer, Jade Cohen, Jane YC. Hui, Jacob Schachter, Nethanel Asher, H. Helgadottir, Harvey Chai, Hidde Kroon, Brendon Coventry, Luke D. Rothermel, James Sun, Matteo S. Carlino, Zoey Duncan, Kristy Broman, Jeffrey Weber, Ann Y. Lee, Russell S. Berman, Jüri Teras, David W. Ollila, Georgina V. Long, Jonathan S. Zager, Alexander van Akkooi & Roger Olofsson Bagge. (2022) The efficacy of immune checkpoint blockade for melanoma in-transit with or without nodal metastases – A multicenter cohort study. European Journal of Cancer 169, pages 210-222.
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E.J. Davies, S.J.M. Reijers, A.C.J. Van Akkooi, W.J. Van Houdt & A.J. Hayes. (2022) Isolated limb perfusion for locally advanced melanoma in the immunotherapy era. European Journal of Surgical Oncology 48:6, pages 1288-1292.
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Zihui Li, Jie Deng, Jianhai Sun & Yanling Ma. (2020) Hyperthermia Targeting the Tumor Microenvironment Facilitates Immune Checkpoint Inhibitors. Frontiers in Immunology 11.
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Junko Johansson, Roberta Kiffin, Annica Andersson, Per Lindnér, Peter L. Naredi, Roger Olofsson Bagge & Anna Martner. (2018) Isolated Limb Perfusion With Melphalan Triggers Immune Activation in Melanoma Patients. Frontiers in Oncology 8.
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Dimitrios Katsarelias, Erik Rådbo, Ilan Ben-Shabat, Jan Mattsson & Roger Olofsson Bagge. (2018) The Effect of Temperature and Perfusion Time on Response, Toxicity, and Survival in Patients with In-transit Melanoma Metastases Treated with Isolated Limb Perfusion. Annals of Surgical Oncology 25:7, pages 1836-1842.
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Ilan Ben-Shabat, Valerio Belgrano, Lars Ny, Jonas Nilsson, Per Lindnér & Roger Olofsson Bagge. (2015) Long-Term Follow-Up Evaluation of 68 Patients with Uveal Melanoma Liver Metastases Treated with Isolated Hepatic Perfusion. Annals of Surgical Oncology 23:4, pages 1327-1334.
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Anna Martner, Junko Johansson, Ilan Ben-Shabat & Roger Olofsson Bagge. (2015) Melphalan, Antimelanoma Immunity, and Inflammation—Letter. Cancer Research 75:24, pages 5398-5399.
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Georgia Beasley & Douglas Tyler. (2014) In-transit Melanoma Metastases: Incidence, Prognosis, and the Role of Lymphadenectomy. Annals of Surgical Oncology 22:2, pages 358-360.
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Christian U. Blank & Alexander Enk. (2015) Therapeutic use of anti-CTLA-4 antibodies. International Immunology 27:1, pages 3-10.
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Betty S. Jiang, Georgia M. Beasley, Paul J. Speicher, Paul J. Mosca, Michael A. Morse, Brent Hanks, April Salama & Douglas S. Tyler. (2014) Immunotherapy Following Regional Chemotherapy Treatment of Advanced Extremity Melanoma. Annals of Surgical Oncology 21:8, pages 2525-2531.
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Michael E. Lidsky, Paul J. Speicher, Betty Jiang, Masahito Tsutsui & Douglas S. Tyler. (2014) Isolated limb infusion as a model to test new agents to treat metastatic melanoma. Journal of Surgical Oncology 109:4, pages 357-365.
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Elizabeth A. Repasky, Sharon S. Evans & Mark W. Dewhirst. (2013) Temperature Matters! And Why It Should Matter to Tumor Immunologists. Cancer Immunology Research 1:4, pages 210-216.
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