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Clinical

Long-term follow-up of 163 consecutive patients treated with isolated limb perfusion for in-transit metastases of malignant melanoma

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Pages 551-557 | Received 18 Jan 2013, Accepted 01 May 2013, Published online: 18 Jul 2013

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Read on this site (8)

Junko Johansson, Roberta Kiffin, Ebru Aydin, Malin S. Nilsson, Kristoffer Hellstrand, Per Lindnér, Peter Naredi, Roger Olofsson Bagge & Anna Martner. (2020) Isolated limb perfusion with melphalan activates interferon-stimulated genes to induce tumor regression in patients with melanoma in-transit metastasis. OncoImmunology 9:1.
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Anna Corderfeldt, Susanne Nielsen, Dimitrios Katsarelias, Anders Hjärpe, Jan Mattsson & Roger Olofsson Bagge. (2019) Is blood a necessary component of the perfusate during isolated limb perfusion – a randomized controlled trial. International Journal of Hyperthermia 36:1, pages 793-799.
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Valerio Belgrano, Jan Mattsson, Jonas Nilsson, Roger Olofsson Bagge & Dimitrios Katsarelias. (2019) BRAF status as a predictive factor for response in isolated limb perfusion. International Journal of Hyperthermia 36:1, pages 510-514.
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Roger Olofsson Bagge, Per Carlson, Roya Razzazian, Christoffer Hansson, Anders Hjärpe, Jan Mattsson & Dimitrios Katsarelias. (2018) Minimally invasive isolated limb perfusion – technical details and initial outcome of a new treatment method for limb malignancies. International Journal of Hyperthermia 35:1, pages 667-673.
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Hansje-Eva Teulings, Esther P. M. Tjin, Karina J. Willemsen, Stephanie van der Kleij, Sylvia ter Meulen, E. Helen Kemp, Gabrielle Krebbers, Carel J. M. van Noesel, Cornelis L. M. C. Franken, Jan W. Drijfhout, Cornelis J. M. Melief, Ludmila Nieuweboer-Krobotova, Omgo E. Nieweg, Jos A. van der Hage, J. P. Wietze van der Veen, Germaine N. Relyveld & Rosalie M. Luiten. (2018) Anti-Melanoma immunity and local regression of cutaneous metastases in melanoma patients treated with monobenzone and imiquimod; a phase 2 a trial. OncoImmunology 7:4.
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Andreas Nyström Wendt, Jan Mattsson & Roger Olofsson Bagge. (2017) Myoglobin does not predict local toxicity in isolated limb perfusion. International Journal of Hyperthermia 33:6, pages 679-683.
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Ilan Ben-Shabat, Valerio Belgrano, Christoffer Hansson & Roger Olofsson Bagge. (2017) The effect of perfusate buffering on toxicity and response in isolated hepatic perfusion for uveal melanoma liver metastases. International Journal of Hyperthermia 33:4, pages 483-488.
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Valerio Belgrano, Ilan Ben-Shabat, Peter Bergh & Roger Olofsson Bagge. (2016) Isolated limb perfusion as a treatment option for rare types of tumours. International Journal of Hyperthermia 32:6, pages 595-599.
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Articles from other publishers (30)

Anna Corderfeldt Keiller, Markus Axelsson, Gudrun Bragadottir, Kaj Blennow, Henrik Zetterberg & Roger Olofsson Bagge. (2023) A prospective feasibility trial exploring novel biomarkers for neurotoxicity after isolated limb perfusion. Perfusion.
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Anne Huibers, Danielle K. DePalo, Matthew C. Perez, Jonathan S. Zager & Roger Olofsson Bagge. (2023) Isolated hyperthermic perfusions for cutaneous melanoma in-transit metastasis of the limb and uveal melanoma metastasis to the liver. Clinical & Experimental Metastasis.
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Anna Corderfeldt Keiller, Anna Holmén, Christoffer Hansson, Sven-Erik Ricksten, Gudrun Bragadottir & Roger Olofsson Bagge. (2022) Non-invasive and invasive measurement of skeletal muscular oxygenation during isolated limb perfusion. Perfusion 38:5, pages 1019-1028.
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Carl-Jacob Holmberg, Jan Mattsson & Roger Olofsson Bagge. (2023) Effects of the Introduction of Modern Immunotherapy on the Outcome of Isolated Limb Perfusion for Melanoma In-Transit Metastases. Cancers 15:2, pages 472.
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Hanna Wesslau, Anders Carlander, Lars Ny, Fredrik Wärnberg, Roger Olofsson Bagge & Ann-Sophie Lindqvist Bagge. (2022) Tumor Burden and Health-Related Quality of Life in Patients with Melanoma In-Transit Metastases. Cancers 15:1, pages 161.
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Carl-Jacob Holmberg, Lars Ny, Tina J. Hieken, Matthew S. Block, Michael J. Carr, Vernon K. Sondak, Christoffer Örtenwall, Dimitrios Katsarelias, Florentia Dimitriou, Alexander M. Menzies, Robyn PM. Saw, Aljosja Rogiers, Richard J. StrakerIIIIII, Giorgos Karakousis, Rona Applewaite, Lalit Pallan, Dale Han, John T. Vetto, David E. Gyorki, Emilia Nan Tie, Maria Grazia Vitale, Paulo A. Ascierto, Reinhard Dummer, Jade Cohen, Jane YC. Hui, Jacob Schachter, Nethanel Asher, H. Helgadottir, Harvey Chai, Hidde Kroon, Brendon Coventry, Luke D. Rothermel, James Sun, Matteo S. Carlino, Zoey Duncan, Kristy Broman, Jeffrey Weber, Ann Y. Lee, Russell S. Berman, Jüri Teras, David W. Ollila, Georgina V. Long, Jonathan S. Zager, Alexander van Akkooi & Roger Olofsson Bagge. (2022) The efficacy of immune checkpoint blockade for melanoma in-transit with or without nodal metastases – A multicenter cohort study. European Journal of Cancer 169, pages 210-222.
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E.J. Davies, S.J.M. Reijers, A.C.J. Van Akkooi, W.J. Van Houdt & A.J. Hayes. (2022) Isolated limb perfusion for locally advanced melanoma in the immunotherapy era. European Journal of Surgical Oncology 48:6, pages 1288-1292.
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Marcello Moro Queiroz, Eduardo Bertolli, Francisco Aparecido Belfort & Rodrigo Ramella Munhoz. (2022) Management of In-Transit Metastases. Current Oncology Reports 24:5, pages 573-583.
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Ayushi Patel, Michael J. Carr, James Sun & Jonathan S. Zager. (2021) In-transit metastatic cutaneous melanoma: current management and future directions. Clinical & Experimental Metastasis 39:1, pages 201-211.
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Lourdes Sevilla-Ortega, Lara Ferrándiz-Pulido, Natalia Palazón-Carrión, María del Carmen Álamo de la Gala, Rubén de Toro-Salas, José Garnacho-Montero, José Antonio Marcos-Rodríguez, Ana Agudo Martínez, Omar Araji-Tiliani, María Cinta Calvo-Morón, José Miguel Barquero-Aroca, Antonio Ramón Fernández-López, José María Jaime-Borrego, Juan Carlos Santos-Jiménez, David Moreno-Ramírez & Luis de la Cruz-Merino. (2021) Role of Isolated Limb Perfusion in the Era of Targeted Therapies and Immunotherapy in Melanoma. A Systematic Review of The Literature. Cancers 13:21, pages 5485.
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Sanni K. A. Tulokas, Laura M. Kohtamäki, Siru P. Mäkelä, Susanna Juteau, Anders Albäck, Pirkka J. Vikatmaa, Kalle E. Mattila, Tanja K. Skyttä, Jussi P. Koivunen, Kristiina Tyynelä-Korhonen & Micaela M. Hernberg. (2021) Isolated limb perfusion with melphalan as treatment for regionally advanced melanoma of the limbs: results of 60 patients treated in Finland during 2007–2018. Melanoma Research 31:5, pages 456-463.
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Rebecca Knackstedt, Timothy Smile, Jennifer Yu & Brian R. Gastman. (2021) Non-Operative Options for Loco-regional Melanoma. Clinics in Plastic Surgery 48:4, pages 631-642.
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Roger Olofsson Bagge, Lars Ny, Paolo A. Ascierto, F. Stephen Hodi, James Larkin, Caroline Robert, Jacob Schachter, Jeffrey S. Weber, Georgina V. Long & Alexander C.J. van Akkooi. (2021) The efficacy of immunotherapy for in-transit metastases of melanoma: an analysis of randomized controlled trials. Melanoma Research 31:2, pages 181-185.
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Emmanuel M. Gabriel, Minhyung Kim, Daniel T. Fisher, Colin Powers, Kristopher Attwood, Sanjay P. Bagaria, Keith L. Knutson & Joseph J. Skitzki. (2020) Dynamic control of tumor vasculature improves antitumor responses in a regional model of melanoma. Scientific Reports 10:1.
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Georgia M. Beasley, Jonathan S. Zager & John F. Thompson. (2019) The Landmark Series: Regional Therapy of Recurrent Cutaneous Melanoma. Annals of Surgical Oncology 27:1, pages 35-42.
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Monica Ekenberg, Hanna Wesslau, Roger Olofsson Bagge & My Engström. (2019) Patient experiences with isolated limb perfusion for malignant melanoma – A qualitative study. European Journal of Oncology Nursing 43, pages 101672.
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Viktor Sandblom, Ingun Ståhl, Christoffer Hansson, Roger Olofsson Bagge & Eva Forssell-Aronsson. (2019) Local treatment of liver metastases by administration of 177Lu-octreotate via isolated hepatic perfusion – A preclinical simulation of a novel treatment strategy. Surgical Oncology 29, pages 148-156.
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Tavis Read, Michael Lonne, David S. Sparks, Michael David, Michael Wagels, Helmut Schaider, H. Peter Soyer & B. Mark Smithers. (2019) A systematic review and meta‐analysis of locoregional treatments for in‐transit melanoma. Journal of Surgical Oncology 119:7, pages 887-896.
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Valerio Belgrano, Jessica Pettersson, Jonas A. Nilsson, Jan Mattsson, Dimitrios Katsarelias & Roger Olofsson Bagge. (2019) Response and Toxicity of Repeated Isolated Limb Perfusion (re-ILP) for Patients With In-Transit Metastases of Malignant Melanoma. Annals of Surgical Oncology 26:4, pages 1055-1062.
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Dimitrios Katsarelias, John Båth, Per Carlson, Jan Mattsson & Roger Olofsson Bagge. (2019) Leakage through the bone-marrow during isolated limb perfusion in the lower extremity. Journal of Surgical Case Reports 2019:4.
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Brianna Cote, Deepa Rao, Raid G. Alany, Glen S. Kwon & Adam W.G. Alani. (2019) Lymphatic changes in cancer and drug delivery to the lymphatics in solid tumors. Advanced Drug Delivery Reviews 144, pages 16-34.
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Dimitrios Katsarelias, Erik Rådbo, Ilan Ben-Shabat, Jan Mattsson & Roger Olofsson Bagge. (2018) The Effect of Temperature and Perfusion Time on Response, Toxicity, and Survival in Patients with In-transit Melanoma Metastases Treated with Isolated Limb Perfusion. Annals of Surgical Oncology 25:7, pages 1836-1842.
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Tavis A. Read, Aaron Smith, Janine Thomas, Michael David, Matthew Foote, Michael Wagels, Andrew Barbour & B. Mark Smithers. (2018) Intralesional PV‐10 for the treatment of in‐transit melanoma metastases—Results of a prospective, non‐randomized, single center study. Journal of Surgical Oncology 117:4, pages 579-587.
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Max F. Madu, Marion M. Deken, Jos A. van der Hage, Katarzyna Jóźwiak, Michel W. J. M. Wouters & Alexander C. J. van Akkooi. (2017) Isolated Limb Perfusion for Melanoma is Safe and Effective in Elderly Patients. Annals of Surgical Oncology 24:7, pages 1997-2005.
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. (2017) Melphalan. Reactions Weekly 1651:1, pages 196-196.
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Lesly A. Dossett, Ilan Ben-Shabat, Roger Olofsson Bagge & Jonathan S. Zager. (2016) Clinical Response and Regional Toxicity Following Isolated Limb Infusion Compared with Isolated Limb Perfusion for In-Transit Melanoma. Annals of Surgical Oncology 23:7, pages 2330-2335.
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Jan P. Deroose, Dirk J. Grünhagen, Alexander M.M. Eggermont & Cornelis Verhoef. (2015) Repeated isolated limb perfusion in melanoma patients with recurrent in-transit metastases. Melanoma Research 25:5, pages 427-431.
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Emmanuel Gabriel & Joseph Skitzki. (2015) The Role of Regional Therapies for in-Transit Melanoma in the Era of Improved Systemic Options. Cancers 7:3, pages 1154-1177.
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Dirk J. GrünhagenHidde M. KroonCornelis Verhoef. (2015) Perfusion and Infusion for Melanoma In-Transit Metastases in the Era of Effective Systemic Therapy. American Society of Clinical Oncology Educational Book:35, pages e528-e534.
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Mark Hurwitz & Paul Stauffer. (2014) Hyperthermia, Radiation and Chemotherapy: The Role of Heat in Multidisciplinary Cancer Care. Seminars in Oncology 41:6, pages 714-729.
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