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Review Article

Chemohyperthermia in non-muscle-invasive bladder cancer: An overview of the literature and recommendations

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Pages 363-373 | Received 11 Dec 2015, Accepted 14 Feb 2016, Published online: 07 Apr 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Iris S. G. Brummelhuis, Johannes Crezee & J. Alfred Witjes. (2023) Evaluation of thermal dose effect in radiofrequency-induced hyperthermia with intravesical chemotherapy for nonmuscle invasive bladder cancer. International Journal of Hyperthermia 40:1.
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F Johannes P van Valenberg, Iris S G Brummelhuis, Lars H Lindner, Felix Kuhnle, Barbara Wedmann, Pascal Schweizer, Martin Hossann, J Alfred Witjes & Egbert Oosterwijk. (2021) DPPG2-Based Thermosensitive Liposomes with Encapsulated Doxorubicin Combined with Hyperthermia Lead to Higher Doxorubicin Concentrations in the Bladder Compared to Conventional Application in Pigs: A Rationale for the Treatment of Muscle-Invasive Bladder Cancer. International Journal of Nanomedicine 16, pages 75-88.
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Yu-Ching Wen, Liang-Ming Lee, Yung-Wei Lin, Syuan-Hao Syu, Ke-Hsun Lin, Yen-Chun Fan, Hsin-Lun Lee, Benjamin Chung Howe Lai & Hung-Jen Shih. (2021) Loco-regional deep hyperthermia combined with intravesical Mitomycin instillation reduces the recurrence of non-muscle invasive papillary bladder cancer. International Journal of Hyperthermia 38:1, pages 1627-1632.
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Astrid van der Horst, H. Petra Kok & Johannes Crezee. (2021) Effect of gastrointestinal gas on the temperature distribution in pancreatic cancer hyperthermia treatment planning. International Journal of Hyperthermia 38:1, pages 229-240.
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Mohamad Moussa, Athanasios G Papatsoris, Athanasios Dellis, Mohamed Abou Chakra & Wajih Saad. (2020) Novel anticancer therapy in BCG unresponsive non-muscle-invasive bladder cancer. Expert Review of Anticancer Therapy 20:11, pages 965-983.
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G. Schooneveldt, H. P. Kok, A. Bakker, E. D. Geijsen, M. C. C. M. Hulshof, T. M. de Reijke & J. Crezee. (2018) The effect of air pockets in the urinary bladder on the temperature distribution during loco-regional hyperthermia treatment of bladder cancer patients. International Journal of Hyperthermia 35:1, pages 441-449.
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Gerben Schooneveldt, H. Petra Kok, Akke Bakker, Elisabeth D. Geijsen, Coen R. N. Rasch, Jean J. M. C. H. de la Rosette, Maarten C. C. M. Hulshof, Theo M. de Reijke & Hans Crezee. (2018) Clinical validation of a novel thermophysical bladder model designed to improve the accuracy of hyperthermia treatment planning in the pelvic region. International Journal of Hyperthermia 35:1, pages 383-397.
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F. Johannes P. van Valenberg, Antoine G. van der Heijden, Rianne J. M. Lammers, Johannes Falke, Tom J. H. Arends, Egbert Oosterwijk & J. Alfred Witjes. (2018) Intravesical radiofrequency induced hyperthermia enhances mitomycin C accumulation in tumour tissue. International Journal of Hyperthermia 34:7, pages 988-993.
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Hans Crezee & Brant A. Inman. (2016) The use of hyperthermia in the treatment of bladder cancer. International Journal of Hyperthermia 32:4, pages 349-350.
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Articles from other publishers (19)

Francesco Claps, Nicola Pavan, Luca Ongaro, Domenico Tierno, Gabriele Grassi, Carlo Trombetta, Gabriele Tulone, Alchiede Simonato, Riccardo Bartoletti, Laura S. Mertens, Bas W. G. van Rhijn, Maria Carmen Mir & Bruna Scaggiante. (2023) BCG-Unresponsive Non-Muscle-Invasive Bladder Cancer: Current Treatment Landscape and Novel Emerging Molecular Targets. International Journal of Molecular Sciences 24:16, pages 12596.
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JJ H. Zhang, Savannah L. Starr & Karim Chamie. (2023) Novel Delivery Mechanisms for Existing Systemic Agents and Emerging Therapies in Bladder Cancer. Bladder Cancer 9:2, pages 109-123.
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Clara Cerrato, Morgan Roupret & Maria Carmen Mir. (2023) Results from HIVEC-II for Intermediate-risk Non–muscle-invasive Bladder Cancer: Is This a Dead End for Mitomycin C Hyperthermia?. European Urology 83:6, pages 505-507.
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Javier C. Angulo, José L. Álvarez-Ossorio, José L. Domínguez-Escrig, José L. Moyano, Alejandro Sousa, Jesús M. Fernández, Francisco Gómez-Veiga, Miguel Unda, Joaquín Carballido, Victor Carrero, Tomás Fernandez-Aparicio, Ángel García de Jalón, Eduardo Solsona, Brant Inman & Joan Palou. (2023) Hyperthermic Mitomycin C in Intermediate-risk Non–muscle-invasive Bladder Cancer: Results of the HIVEC-1 Trial. European Urology Oncology 6:1, pages 58-66.
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Peng ZhangYi Ding. (2022) Novel Therapeutic Strategies for BCG-unresponsive Non-muscle Invasive Bladder Cancer. annals of urologic oncology, pages 1-9.
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Matthieu Simonet, Ana Dominguez Gutierrez, Angelo Territo, Thomas Prudhomme, Ricardo Campi, Iulia Andras, Michael Baboudjian, Vital Hevia & Romain Boissier. (2022) Systematic review on oncologic outcomes on adjuvant endovesical treatment for non-muscle invasive bladder cancer in patients with solid organ transplant. World Journal of Urology 40:12, pages 2901-2910.
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Weijian Zhou, Jianping Liu, Dongdong Mao, Changying Hu & Dianjun Gao. (2022) The clinical efficacy and safety of equipment-assisted intravesical instillation of mitomycin C after transurethral resection of bladder tumour in patients with nonmuscular invasive bladder cancer: A meta-analysis. PLOS ONE 17:10, pages e0276453.
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Kelly Ward, Mark O Kitchen, Suresh-Jay Mathias, Farhat L Khanim & Richard T. Bryan. (2022) Novel intravesical therapeutics in the treatment of non-muscle invasive bladder cancer: Horizon scanning. Frontiers in Surgery 9.
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You Li, Shams F. Youssef & Asma BM. Buanz. (2022) Intravesical combination therapies for non-muscle invasive bladder cancer: Recent advances and future directions. European Journal of Pharmacology 926, pages 175024.
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Morteza Ghaderi Aram, Hadi Aliakbarian & Hana Dobšíček Trefná. (2022) An ultra‐wideband compact design for hyperthermia: Open ridged‐waveguide antenna. IET Microwaves, Antennas & Propagation 16:2-3, pages 137-152.
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Ana Plata, Félix Guerrero-Ramos, Carlos Garcia, Alejandro González-Díaz, Ignacio Gonzalez-Valcárcel, José Manuel de la Morena, Francisco Javier Díaz-Goizueta, Julio Fernández del Álamo, Victoria Gonzalo, Javier Montero, Alejandro Sousa-Escandón, Juan León, Jose Luis Pontones, Francisco Delgado, Miguel Adriazola, Ángela Pascual, Jesús Calleja, Ana Ruano, Luis Martínez-Piñeiro & Javier C. Angulo. (2021) Long-Term Experience with Hyperthermic Chemotherapy (HIVEC) Using Mitomycin-C in Patients with Non-Muscle Invasive Bladder Cancer in Spain. Journal of Clinical Medicine 10:21, pages 5105.
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YuvarajaB Thyavihally, SantoshS Waigankar, Preetham Dev, Ashish Asari, AbhinavP Pednekar, Nevitha Athikari, Abhijit Raut, Archan Khandekar & Naresh Badlani. (2021) Comparing adverse effects, short term outcomes, and cost implications of hyperthermic intravesical chemotherapy with Mitomycin-C and intravesical bacillus Calmette–Guerin instillation (Moscow-I strain) in the management of intermediate and high-risk nonmuscle invasive bladder cancer. Urology Annals 13:4, pages 424.
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Emsad Puric, Emanuel Stutz, Lars Lindner, Andreas Meister, Thomas Kern, Niloy R. Datta, Susanne J. Rogers & Oliver Riesterer. (2020) Hyperthermie in der Therapie von malignen Beckentumoren. InFo Hämatologie + Onkologie 23:7-8, pages 35-44.
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Dunia Khaled, John Taylor & Jeffrey Holzbeierlein. (2020) Salvage Therapy for Non–muscle-invasive Bladder Cancer. Urologic Clinics of North America 47:1, pages 119-128.
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Niloy Ranjan Datta, Emanuel Stutz, Emsad Puric, Brigitte Eberle, Andreas Meister, Dietmar Marder, Olaf Timm, Susanne Rogers, Stephen Wyler & Stephan Bodis. (2019) A Pilot Study of Radiotherapy and Local Hyperthermia in Elderly Patients With Muscle-Invasive Bladder Cancers Unfit for Definitive Surgery or Chemoradiotherapy. Frontiers in Oncology 9.
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Gerben Schooneveldt, Hana Dobšíček Trefná, Mikael Persson, Theo M. de Reijke, Klas Blomgren, H. Petra Kok & Hans Crezee. (2019) Hyperthermia Treatment Planning Including Convective Flow in Cerebrospinal Fluid for Brain Tumour Hyperthermia Treatment Using a Novel Dedicated Paediatric Brain Applicator. Cancers 11:8, pages 1183.
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F. Johannes P. van Valenberg, Amir Kajtazovic, Giorgio Canepa, Gerson Lüdecke, Jill-Isabel Kilb, Katja K. H. Aben, Ofer Nativ, Sanjeev Madaan, Benjamin Ayres, Rami Issa & J. Alfred Witjes. (2018) Intravesical Radiofrequency-Induced Chemohyperthermia for Carcinoma in Situ of the Urinary Bladder: A Retrospective Multicentre Study. Bladder Cancer 4:4, pages 365-376.
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W.‑D. U. Böhm, R. Koch, S. Wenzel, M. P. Wirth & M. Toma. (2018) Zur urogenitalen Klinik der lokalisierten/systemischen BCGitisDevelopment and treatment of localized/systemic BCGitis. Der Urologe 57:5, pages 568-576.
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Christian Gorsche, Christoph Schnoell, Thomas Koch, Norbert Moszner & Robert Liska. (2018) Debonding on Demand with Highly Cross-Linked Photopolymers: A Combination of Network Regulation and Thermally Induced Gas Formation. Macromolecules 51:3, pages 660-669.
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