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Original Article

Oxidative stress on lens and cataract formation: role of light and oxygen

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Pages 35-58 | Published online: 02 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (27)

Karen L. Christopher, Jennifer L. Patnaik, Kylie J. Penland, Mina B. Pantcheva, Anne M. Lynch & Cristos Ifantides. (2023) Outcomes and Risk Factors for Complications in Cataract Patients with Hepatitis C Virus Infection. Ophthalmic Epidemiology 30:5, pages 492-498.
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Shambhu D Varma. (2016) Effect of coffee (caffeine) against human cataract blindness. Clinical Ophthalmology 10, pages 213-220.
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Shambhu D Varma, Krish Chandrasekaran & Svitlana Kovtun. (2013) Sulforaphane-induced transcription of thioredoxin reductase in lens: possible significance against cataract formation. Clinical Ophthalmology 7, pages 2091-2098.
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R. Thiagarajan & R. Manikandan. (2013) Antioxidants and cataract. Free Radical Research 47:5, pages 337-345.
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R. Manikandan, R. Thiagarajan, S. Beulaja, G. Sudhandiran & M. Arumugam. (2010) Effect of Curcumin on Selenite-Induced Cataractogenesis in Wistar Rat Pups. Current Eye Research 35:2, pages 122-129.
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Shambhu D Varma & Kavita R Hegde. (2007) Oxidative stress and cataract formation: horizons on its medical prevention. Expert Review of Ophthalmology 2:5, pages 779-801.
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R. Elanchezhian, E. Ramesh, M. Sakthivel, M. Isai, P. Geraldine, M. Rajamohan, C. Nelson Jesudasan & P. A. Thomas. (2007) Acetyl-L-Carnitine Prevents Selenite-Induced Cataractogenesis in an Experimental Animal Model. Current Eye Research 32:11, pages 961-971.
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Sandeep Saxena, Prachi Srivastava, Dipak Kumar, Vinay K. Khanna & Prahlad K. Seth. (2006) Decreased Platelet Membrane Fluidity in Retinal Periphlebitis in Eales' Disease. Ocular Immunology and Inflammation 14:2, pages 113-116.
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Kerstin Nau-Staudt, Werner M. Nau, Ivan O. Haefliger & Josef Flammer. (2001) Lipid peroxidation in porcine irises: Dependence on pigmentation. Current Eye Research 22:3, pages 229-234.
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S. D. Varma, P. S. Devamanoharan & A. H. Ali. (1998) Prevention of Intracellular Oxidative Stress to Lens by Pyruvate and Its Ester. Free Radical Research 28:2, pages 131-135.
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John S. Ambler, Lawrence W. Hirst, Charles V. Clarke & Adele C. Green. (1995) The Nambour study of ocular disease. I. Design, study population and methodology. Ophthalmic Epidemiology 2:3, pages 137-144.
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Fusun Kilic & John R. Trevithick. (1995) Vitamin C reduces cytochalasin D cataractogenesis. Current Eye Research 14:10, pages 943-949.
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S. D. Varma, P.S. Devamanoharan & S. M. Morris. (1995) Prevention of cataracts by nutritional and metabolic antioxidants. Critical Reviews in Food Science and Nutrition 35:1-2, pages 111-129.
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YogR. Sharma, RasikB. Vajpayee & SantoshG. Honavar. (1994) Sunlight and Cortical Cataract. Archives of Environmental Health: An International Journal 49:5, pages 414-417.
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A Taylor. (1993) Cataract: relationship between nutrition and oxidation.. Journal of the American College of Nutrition 12:2, pages 138-146.
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Norman J. Kleiman & Abraham Spector. (1993) DNA single strand breaks in human lens epithelial cells from patients with cataract. Current Eye Research 12:5, pages 423-431.
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Abraham Spector, Guo-Ming Wang, Ren-Rong Wang, William H. Garner & Hans Moll. (1993) The prevention of cataract caused by oxidative stress in cultured rat lenses. I. H2O2 and photochemically induced cataract. Current Eye Research 12:2, pages 163-179.
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J.P. Singh & S. Singh. (1992) Senile cataract‐a biochemical approach and in vivo regulation of calcium and phosphate. Journal of Environmental Science and Health . Part A: Environmental Science and Engineering and Toxicology 27:5, pages 1273-1292.
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S. D. Varma & P. S. Devamanoharan. (1991) Hydrogen Peroxide in Human Blood. Free Radical Research Communications 14:2, pages 125-131.
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Palaniyandi S. Devamanoharan, Sankar Ramachandran & Shambhu D. Varma. (1991) Hydrogen peroxide in the eye lens: radioisotopic determination. Current Eye Research 10:9, pages 831-838.
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J.P. Singh, R.B. Misra, L.P. Srivastava & P.C. Joshi. (1990) Photoinduced effect of riboflavin in ocular tissues. Journal of Environmental Science and Health . Part A: Environmental Science and Engineering and Toxicology 25:3, pages 267-275.
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S. Persad, I. A. Menon, P. K. Basu & F. Carre. (1988) Phototoxicity of chlorpromazine on retinal pigment epithelial cells. Current Eye Research 7:1, pages 1-9.
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Garry R. Buettner & Prof. G. Czapski. (1986) Ascorbate Autoxidation in the Presence of Iron and Copper Chelates. Free Radical Research Communications 1:6, pages 349-353.
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Hideo Nishigori, Jung W. Lee, Yasuhisa Yamauchi & Motoharu Iwatsuru. (1986) The alteration of lipid peroxide in glucocorticoid-induced cataract of developing chick embryos and the effect of ascorbic acid. Current Eye Research 5:1, pages 37-40.
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Pierrette Dayhaw-Barker & Felix M. Barker. (1985) Photoeffects on the Eye. Journal of Toxicology: Cutaneous and Ocular Toxicology 4:3-4, pages 269-299.
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Peggy S. Zelenka. (1984) Lens lipids. Current Eye Research 3:11, pages 1337-1359.
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