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Research Article

Design for Drug-Excipient Interaction Studies

Pages 43-55 | Published online: 20 Oct 2008

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Parag Roy, Nimmy Kumari, Noopur Pandey, Abhishek Gour, Amit Raj, B. Srividya, Utpal Nandi & Animesh Ghosh. (2022) Development of ezetimibe eutectic with improved biopharmaceutical and mechanical properties to design an optimized oral solid dosage formulation. Pharmaceutical Development and Technology 27:10, pages 989-998.
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Kira-Isabel Zier, Wulf Schultze, Uta Sazama, Michael Fröba & Claudia S. Leopold. (2020) Stabilizing and destabilizing effects of drug-excipient interactions in spray-dried, freeze-dried, and granulated Sennae fructus extracts. Drying Technology 38:14, pages 1882-1890.
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Monika Stojanovska Pecova, Nikola Geskovski, Gjorgji Petrushevski, Marina Chachorovska, Liljana Krsteska, Sonja Ugarkovic & Petre Makreski. (2020) Solid-state interaction of ibuprofen with magnesium stearate and product characterization thereof. Drug Development and Industrial Pharmacy 46:8, pages 1308-1317.
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Prakash Niguram, Surya Narayana Polaka, Rajeshwari Rathod, Kiran Kalia & Abhijeet S. Kate. (2020) Update on compatibility assessment of empagliflozin with the selected pharmaceutical excipients employed in solid dosage forms by thermal, spectroscopic and chromatographic techniques. Drug Development and Industrial Pharmacy 46:2, pages 209-218.
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Marzia Cirri, M. Francesca Righi, Francesca Maestrelli, Paola Mura & Maurizio Valleri. (2009) Development of Glyburide Fast-Dissolving Tablets Based on the Combined Use of Cyclodextrins and Polymers. Drug Development and Industrial Pharmacy 35:1, pages 73-82.
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Nicole Wyttenbach, Christian Birringer, Jochem Alsenz & Martin Kuentz. (2005) Drug-Excipient Compatibility Testing Using a High-Throughput Approach and Statistical Design. Pharmaceutical Development and Technology 10:4, pages 499-505.
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M. L. Vueba, F. Veiga, J. J. Sousa & Maria Eugénia Pina. (2005) Compatibility Studies Between Ibuprofen or Ketoprofen with Cellulose Ether Polymer Mixtures Using Thermal Analysis. Drug Development and Industrial Pharmacy 31:10, pages 943-949.
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B. V. Joshi, V. B. Patil & V. B. Pokharkar. (2002) Compatibility Studies Between Carbamazepine and Tablet Excipients Using Thermal and Non-thermal Methods. Drug Development and Industrial Pharmacy 28:6, pages 687-694.
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N. Muñoz, C. Ferrero, A. Muñoz-Ruiz, M. V. Velasco & M. R. Jiménez-Castellanos. (1998) Effect of Explotab® on the Tabletability of a Poorly Soluble Drug. Drug Development and Industrial Pharmacy 24:8, pages 785-791.
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P. Mura, M. T. Faucci, A. Manderioli, S. Furlanetto & S. Pinzauti. (1998) Thermal Analysis as a Screening Technique in Preformulation Studies of Picotamide Solid Dosage Forms. Drug Development and Industrial Pharmacy 24:8, pages 747-756.
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C. E. P. Malan, M. M. De Villiers & A. P. Lötter. (1997) Evaluation of Compatibility of Tablet Excipients with Albendazole and Closantel Using DSC and HPLC. Drug Development and Industrial Pharmacy 23:6, pages 533-537.
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S. Venkataram, M. Khohlokwane & S. H. Wallis. (1995) Differential Scanning Calorimetry as a Quick Scanning Technique for Solid State Stability Studies. Drug Development and Industrial Pharmacy 21:7, pages 847-855.
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Sigmund A. Schildcrout, Donald S. Risley & Rita L. Kleemann. (1993) Drug-Excipient Interactions of Seproxetine Maleate Hemi-Hydrate: Isothermal Stress Methods. Drug Development and Industrial Pharmacy 19:10, pages 1113-1130.
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K. J. Hartauer & J. K. Guillory. (1991) A Comparison of diffuse Reflectance Ft-Ir Spectroscopy and Dsc in the Characterization of a Drug-Excipient Interaction. Drug Development and Industrial Pharmacy 17:4, pages 617-630.
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E. C. Van Tonder, S. A. Botha & A. P. Lötter. (1991) Moisture the dominant factor in the stability of doxylamine succinate tablets. Drug Development and Industrial Pharmacy 17:1, pages 157-163.
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E. Ben-rayana, A. Seddas, P. Ruelle, Hø Nam-Tran & U.W. Kesselring. (1990) Influence of Water Adsorbed on Avicel PH 101® on the Thermal Decomposition of p− Aminosalicylic Acid. Molecular Crystals and Liquid Crystals Incorporating Nonlinear Optics 187:1, pages 357-364.
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S. A. Botha & A. P. Lötter. (1990) Compatiblity Study Between Oxprenolol Hydrochloride, Temazepam and Tablet Excipients using Differential Scanning Calorimetry. Drug Development and Industrial Pharmacy 16:2, pages 331-345.
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S. A. Botha & A. P. Lötter. (1990) Compatibility Study Between Naproxen and Tablet Excipients Using Differential Scanning Calorimetry. Drug Development and Industrial Pharmacy 16:4, pages 673-683.
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S. A. Botha & A. P. Lötter. (1990) Compatibility Study Between Atenolol and Tablet Excipients Using Differential Scanning Calorimetry. Drug Development and Industrial Pharmacy 16:12, pages 1945-1954.
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Donald C. Monkhouse & Agnes Maderich. (1989) Whither Compatibility Testing?. Drug Development and Industrial Pharmacy 15:13, pages 2115-2130.
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S. A. Botha & A. P. Lötter. (1989) Compatibility study between oxprenolol hydrochloride and tablet excipients using differential scanning calorimetry. Drug Development and Industrial Pharmacy 15:11, pages 1843-1853.
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S. A. Botha & A. P. Lötter. (1989) Compatibility Study Between Ketoprofen and Tablet Excipients Using Differential Scanning Calorimetry. Drug Development and Industrial Pharmacy 15:3, pages 415-426.
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F. Carli, P. Iamartino & E. Ciranni Signoretti. (1988) The Influence of Granulation Process and Surfactants on the Biopharmaceutical Properties of Phenylbutazone Tablets. Drug Development and Industrial Pharmacy 14:12, pages 1713-1734.
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S. L. Law, W. Y. Lo, F. M. Lin & C. H. Chiang. (1988) Compatibility Study of Propoxyphene HCL Solid Mixtures Using Differential Scanning Calorimetry. Drug Development and Industrial Pharmacy 14:10, pages 1465-1470.
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E. Ciranni Signoretti, C. De Sena, A. Dell'Utri & S. Alimonti. (1988) An Investigation into Eventual Interactions between Clenbuterol and Some Mucolytic Drugs by Differential Scanning Calorimetry. Drug Development and Industrial Pharmacy 14:9, pages 1167-1184.
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HÅRkan Nyqvist. (1986) Preformulation Studies of Drug Substances for Solid Dosage Forms. Drug Development and Industrial Pharmacy 12:7, pages 953-968.
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S. A. Botha, J. L. Du Preez & A. P. Lötter. (1986) DSC Screening for Drug-Drug and Drug-Excipient Interactions in Polypharmaceuticals Intended for the Alleviation of the Symptoms of Colds and Flu. I. Drug Development and Industrial Pharmacy 12:6, pages 811-827.
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Francis A. Chrzanowski, Lucy A. Ulissi, Barry J. Fegely & Azarine C. Newman. (1986) Preformulation Excipient Compatibility Testing. Application of a Differential Scanning Cal0Rimetric Method Versus a Wei Granulation Simulating, Isothermal Stress Method. Drug Development and Industrial Pharmacy 12:6, pages 783-800.
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E. Ciranni Signoretti, A. Dell'utri, A. De Salvo & L. Donini. (1986) Compatibility Study Between Clenbuterol and Tablet Excipients Using Differential Scanning Calorimetry. Drug Development and Industrial Pharmacy 12:4, pages 603-620.
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Krissia Wilhelm Romero, María Isabel Quirós, Felipe Vargas Huertas, José Roberto Vega-Baudrit, Mirtha Navarro-Hoyos & Andrea Mariela Araya-Sibaja. (2021) Design of Hybrid Polymeric-Lipid Nanoparticles Using Curcumin as a Model: Preparation, Characterization, and In Vitro Evaluation of Demethoxycurcumin and Bisdemethoxycurcumin-Loaded Nanoparticles. Polymers 13:23, pages 4207.
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Cansel Kose Ozkan, Ozgur Esim, Ayhan Savaser & Yalcin Ozkan. (2021) An Overview of Excipients Classification and Their Use in Pharmaceuticals. Current Pharmaceutical Analysis 17:3, pages 360-374.
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Faranak Ghaderi & Farnaz Monajjemzadeh. (2020) Review of the physicochemical methods applied in the investigation of the maillard reaction in pharmaceutical preparations. Journal of Drug Delivery Science and Technology 55, pages 101362.
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A.S. Narang, R.V. Mantri & K.S. Raghavan. 2017. Developing Solid Oral Dosage Forms. Developing Solid Oral Dosage Forms 151 179 .
Paroma Chakravarty, Sanjeev Kothari, Alan Deese & Joseph W. Lubach. (2015) Solid-State Characterization of Novel Propylene Glycol Ester Solvates Isolated from Lipid Formulations. Molecular Pharmaceutics 12:7, pages 2551-2557.
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Eleftheria Roumeli, Angelina Tsiapranta, Eleni Pavlidou, Georgios Vourlias, Kyriakos Kachrimanis, Dimitrios Bikiaris & Konstantinos Chrissafis. (2012) Compatibility study between trandolapril and natural excipients used in solid dosage forms. Journal of Thermal Analysis and Calorimetry 111:3, pages 2109-2115.
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Sanjay Shah, Sarika Madan & SS Agrawal. (2012) Formulation and evaluation of microsphere based oro dispersible tablets of itopride hcl. DARU Journal of Pharmaceutical Sciences 20:1.
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Karin Liltorp, Trine Gorm Larsen, Birgitte Willumsen & René Holm. (2011) Solid state compatibility studies with tablet excipients using non thermal methods. Journal of Pharmaceutical and Biomedical Analysis 55:3, pages 424-428.
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