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Review Article

Colonic Drug Targeting

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Pages 129-149 | Received 04 Feb 1997, Accepted 14 Oct 1997, Published online: 26 Jun 2009

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Manoj Kumar Sarangi, M. E. Bhanoji Rao & Versha Parcha. (2021) Smart polymers for colon targeted drug delivery systems: a review. International Journal of Polymeric Materials and Polymeric Biomaterials 70:16, pages 1130-1166.
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Sima Singh, Niranjan G Kotla, Sonia Tomar, Balaji Maddiboyina, Thomas J Webster, Dinesh Sharma & Omprakash Sunnapu. (2015) A nanomedicine-promising approach to provide an appropriate colon-targeted drug delivery system for 5-fluorouracil. International Journal of Nanomedicine 10, pages 7175-7182.
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Sanjay J. Kshirsagar, Mangesh R. Bhalekar, Jiten N. Patel, Santosh K. Mohapatra & Nitin S. Shewale. (2012) Preparation and characterization of nanocapsules for colon-targeted drug delivery system. Pharmaceutical Development and Technology 17:5, pages 607-613.
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Nahla S. Barakat, Saleh A. Al-Suwayeh, Ehab I. Taha & Alaa Eldeen Bakry Yassin. (2011) A new pressure-controlled colon delivery capsule for chronotherapeutic treatment of nocturnal asthma. Journal of Drug Targeting 19:5, pages 365-372.
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V. R. Sinha, R. V. Kumar & J. R. Bhinge. (2009) Influence of Polymeric Blend of Carbomer-Gum on the Targeted Delivery of 5-FU. Polymer-Plastics Technology and Engineering 48:12, pages 1287-1294.
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Mayur M. Patel, Tejal J. Shah, Avani F. Amin & Nitesh N. Shah. (2009) Design, Development and Optimization of a Novel Time and pH-Dependent Colon Targeted Drug Delivery System. Pharmaceutical Development and Technology 14:1, pages 65-72.
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Laila Fatima Ali Asghar & Sajeev Chandran. (2008) Design and evaluation of matrices of Eudragit with polycarbophil and carbopol for colon-specific delivery. Journal of Drug Targeting 16:10, pages 741-757.
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Marta Roldo, Eugen Barbu, James F Brown, David W Laight, John D Smart & John Tsibouklis. (2007) Azo compounds in colon-specific drug delivery. Expert Opinion on Drug Delivery 4:5, pages 547-560.
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Soodabeh Davaran, Mohammad R. Rashidi & Abbas Khani. (2007) Synthesis of Chemically Cross-Linked Hydroxypropyl Methyl Cellulose Hydrogels and their Application in Controlled Release of 5-Amino Salicylic Acid. Drug Development and Industrial Pharmacy 33:8, pages 881-887.
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V. R. Sinha, J. R. Bhinge, Rachna Kumria & Manoj Kumar. (2006) Development of Pulsatile Systems for Targeted Drug Delivery of Celecoxib for Prophylaxis of Colorectal Cancer. Drug Delivery 13:3, pages 221-225.
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ShanthaL. Kosaraju. (2005) Colon Targeted Delivery Systems: Review of Polysaccharides for Encapsulation and Delivery. Critical Reviews in Food Science and Nutrition 45:4, pages 251-258.
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Filippos Kesisoglou & Ellen M Zimmermann. (2005) Novel drug delivery strategies for the treatment of inflammatory bowel disease. Expert Opinion on Drug Delivery 2:3, pages 451-463.
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Hiraku Onishi, Tomoko Oosegi, Yoshiharu Machida & James W. McGinity. (2005) Preparation and In Vitro Evaluation of Chitosan Microspheres Containing Prednisolone: Comparison of Simple and Conjugate Microspheres. Drug Development and Industrial Pharmacy 31:7, pages 597-605.
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J. Alvarez-Fuentes, M. Fernández-Arévalo, M.L. González-Rodríguez, M. Cirri & P. Mura. (2004) Development of Enteric-coated Timed-release Matrix Tablets for Colon Targeting. Journal of Drug Targeting 12:9-10, pages 607-612.
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Meiling Qi, Peng Wang & Dezheng Wu. (2003) A Novel pH- and Time-Dependent System for Colonic Drug Delivery. Drug Development and Industrial Pharmacy 29:6, pages 661-667.
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Osvaldo Albuquerque Cavalcanti, Guy Van den Mooter, Ida Caramico-Soares & Renaat Kinget. (2002) Polysaccharides as Excipients for Colon-Specific Coatings. Permeability and Swelling Properties of Casted Films. Drug Development and Industrial Pharmacy 28:2, pages 157-164.
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Zhaopeng Hu, Tatsuharu Shimokawa, Tomoya Ohno, Go Kimura, Shun-Suke Mawatari, Megumi Kamitsuna, Yukako Yoshikawa, Shigeki Masuda & Kanji Takada. (1999) Characterization of Norfloxacine Release from Tablet Coated with a New pH-Sensitive Polymer, P-4135F. Journal of Drug Targeting 7:3, pages 223-232.
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V.R. Sinha, B.R. Mittal & Rachna Kumria. (2005) In vivo evaluation of time and site of disintegration of polysaccharide tablet prepared for colon-specific drug delivery. International Journal of Pharmaceutics 289:1-2, pages 79-85.
Crossref
S.M. Al-Saidan, Y.S.R. Krishnaiah, V. Satyanarayana, P. Bhaskar & R.S. Karthikeyan. (2004) Pharmacokinetic evaluation of guar gum-based three-layer matrix tablets for oral controlled delivery of highly soluble metoprolol tartrate as a model drug. European Journal of Pharmaceutics and Biopharmaceutics 58:3, pages 697-703.
Crossref
Alf Lamprecht, Hiromitsu Yamamoto, Hirofumi Takeuchi & Yoshiaki Kawashima. (2004) Design of pH-sensitive microspheres for the colonic delivery of the immunosuppressive drug tacrolimus. European Journal of Pharmaceutics and Biopharmaceutics 58:1, pages 37-43.
Crossref
Lee F Siew, Sit-Ming Man, J.Michael Newton & Abdul W Basit. (2004) Amylose formulations for drug delivery to the colon: a comparison of two fermentation models to assess colonic targeting performance in vitro. International Journal of Pharmaceutics 273:1-2, pages 129-134.
Crossref
Tamara Minko. (2004) Drug targeting to the colon with lectins and neoglycoconjugates. Advanced Drug Delivery Reviews 56:4, pages 491-509.
Crossref
Gang Cheng. (2004) Time- and pH-dependent colon-specific drug delivery for orally administered diclofenac sodium and 5-aminosalicylic acid. World Journal of Gastroenterology 10:12, pages 1769.
Crossref
V.R Sinha, B.R Mittal, K.K Bhutani & Rachna Kumria. (2004) Colonic drug delivery of 5-fluorouracil: an in vitro evaluation. International Journal of Pharmaceutics 269:1, pages 101-108.
Crossref
Pieter van der Bijl & Armorel D van Eyk. (2003) Comparative in vitro permeability of human vaginal, small intestinal and colonic mucosa. International Journal of Pharmaceutics 261:1-2, pages 147-152.
Crossref
V.R Sinha & Rachna Kumria. (2003) Microbially triggered drug delivery to the colon. European Journal of Pharmaceutical Sciences 18:1, pages 3-18.
Crossref
V.R Sinha & Rachna Kumria. (2002) Binders for colon specific drug delivery: an in vitro evaluation. International Journal of Pharmaceutics 249:1-2, pages 23-31.
Crossref
Y.S.R Krishnaiah, R.S Karthikeyan & V Satyanarayana. (2002) A three-layer guar gum matrix tablet for oral controlled delivery of highly soluble metoprolol tartrate. International Journal of Pharmaceutics 241:2, pages 353-366.
Crossref
A. Van Laere & W. Van Den Ende. (2002) Inulin metabolism in dicots: chicory as a model system. Plant, Cell & Environment 25:6, pages 803-813.
Crossref
Libo Yang, James S Chu & Joseph A Fix. (2002) Colon-specific drug delivery: new approaches and in vitro/in vivo evaluation. International Journal of Pharmaceutics 235:1-2, pages 1-15.
Crossref
Jinhe Li, Libo Yang, Sheila M. Ferguson, Tom J. Hudson, Shunsuke Watanabe, Masataka Katsuma & Joseph A. Fix. (2002) In vitro evaluation of dissolution behavior for a colon-specific drug delivery system (CODES™) in multi-pH media using United States Pharmacopeia apparatus II and III. AAPS PharmSciTech 3:4.
Crossref
P Nyk?nen, S Lemp??M.-L Aaltonen, H J?rjenson, P Veski & M Marvola. (2001) Citric acid as excipient in multiple-unit enteric-coated tablets for targeting drugs on the colon. International Journal of Pharmaceutics 229:1-2, pages 155-162.
Crossref
Alf Lamprecht, Nathalie Ubrich, Hiromitsu Yamamoto, Ulrich Schäfer, Hirofumi Takeuchi, Claus-Michael Lehr, Philippe Maincent & Yoshiaki Kawashima. (2001) Design of rolipram-loaded nanoparticles: comparison of two preparation methods. Journal of Controlled Release 71:3, pages 297-306.
Crossref
Young-Il Jeong, Tomoya Ohno, Zhaopeng Hu, Yukako Yoshikawa, Nobuhito Shibata, Shunji Nagata & Kanji Takada. (2001) Evaluation of an intestinal pressure-controlled colon delivery capsules prepared by a dipping method. Journal of Controlled Release 71:2, pages 175-182.
Crossref
F. Hirayama, T. Ogata, H. Yano, H. Arima, K. Udo, M. Takano & K. Uekama. (2000) Release characteristics of a short‐chain fatty acid, n‐butyric acid, from its β‐cyclodextrin ester conjugate in rat biological media. Journal of Pharmaceutical Sciences 89:11, pages 1486-1495.
Crossref
Reinhard Paschke, Jutta Kalbitz & Christian Paetz. (2000) Novel spacer linked bile acid?cisplatin compounds as a model for specific drug delivery, synthesis and characterization. Inorganica Chimica Acta 304:2, pages 241-249.
Crossref
Nobuhito Shibata, Tatsuharu Shimokawa, Zhi-Qiang Jiang, Young-Il Jeong, Tomoya Ohno, Go Kimura, Yukako Yoshikawa, Kenji Koga, Masahiro Murakami & Kanji Takada. (2000) Characteristics of intestinal absorption and disposition of glycyrrhizin in mice. Biopharmaceutics & Drug Disposition 21:3, pages 95-101.
Crossref
Liesbeth Vervoort, Guy Van den Mooter, Patrick Augustijns & Renaat Kinget. (1998) Inulin hydrogels. I. Dynamic and equilibrium swelling properties. International Journal of Pharmaceutics 172:1-2, pages 127-135.
Crossref

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