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Research Article

Transdermal delivery of meloxicam using niosomal hydrogels: in vitro and pharmacodynamic evaluation

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Pages 820-826 | Received 14 Feb 2014, Accepted 18 May 2014, Published online: 09 Jun 2014

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Abeer S Hassan, Amal Hofni, Mohammed AS Abourehab & Iman AM Abdel-Rahman. (2023) Ginger Extract–Loaded Transethosomes for Effective Transdermal Permeation and Anti-Inflammation in Rat Model. International Journal of Nanomedicine 18, pages 1259-1280.
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Hussein M Eid, Adel A Ali, Ahmed M Abdelhaleem Ali, Essam M Eissa, Randa M Hassan, Fatma I Abo El-Ela & Amira H Hassan. (2022) Potential Use of Tailored Citicoline Chitosan-Coated Liposomes for Effective Wound Healing in Diabetic Rat Model. International Journal of Nanomedicine 17, pages 555-575.
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Ayat Allam & Gihan Fetih. (2016) Sublingual fast dissolving niosomal films for enhanced bioavailability and prolonged effect of metoprolol tartrate. Drug Design, Development and Therapy 10, pages 2421-2433.
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Jianmin Chen & Yunhua Gao. (2016) Strategies for meloxicam delivery to and across the skin: a review. Drug Delivery 23:8, pages 3146-3156.
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Ahlam Zaid Alkilani, Rania Hamed, Hajer Abdo, Lubna Swellmeen, Haneen A. Basheer, Walaa Wahdan & Amani D. Abu Kwiak. (2022) Formulation and Evaluation of Azithromycin-Loaded Niosomal Gel: Optimization, In Vitro Studies, Rheological Characterization, and Cytotoxicity Study. ACS Omega 7:44, pages 39782-39793.
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Tamer M. Mahmoud, Mohamed M. Nafady, Hanan O. Farouk, Dina M. Mahmoud, Yasmin M. Ahmed, Randa Mohammed Zaki & Doaa S. Hamad. (2022) Novel Bile Salt Stabilized Vesicles-Mediated Effective Topical Delivery of Diclofenac Sodium: A New Therapeutic Approach for Pain and Inflammation. Pharmaceuticals 15:9, pages 1106.
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Marina A. Bekhet, Adel A. Ali, Rasha M. Kharshoum, Fatma I. Abo El-Ela & Heba F. Salem. (2022) Intranasal Niosomal In Situ Gel As A Novel Strategy for Improving Citicoline Efficacy and Brain Delivery in Treatment of Epilepsy: In Vitro and Ex Vivo Characterization and In Vivo Pharmacodynamics Investigation. Journal of Pharmaceutical Sciences 111:8, pages 2258-2269.
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Ayat A. Allam, Nermin E. Eleraky, Nadeen H. Diab, Mahmoud Elsabahy, Sahar A. Mohamed, Hala S. Abdel-Ghaffar, Nivin A. Hassan, Samia A. Shouman, Mervat M. Omran, Sahar B. Hassan & Noura G. Eissa. (2022) Development of Sedative Dexmedetomidine Sublingual In Situ Gels: In Vitro and In Vivo Evaluations. Pharmaceutics 14:2, pages 220.
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Marwa Hasanein Asfour, Sameh Hosam Abd El-Alim, Ghada Elsayed Ahmed Awad & Ahmed Alaa Kassem. (2021) Chitosan/β-glycerophosphate in situ forming thermo-sensitive hydrogel for improved ocular delivery of moxifloxacin hydrochloride. European Journal of Pharmaceutical Sciences 167, pages 106041.
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Mahmoud M. A. Elsayed, Saleh Abd El Rasoul, Abd El hakim Ramadan & Amal K. Hussein. (2019) Response Surface Methodology as a Useful Tool for Development and Optimization of Sustained Release Ketorolac Tromethamine Niosomal Organogels. Journal of Pharmaceutical Innovation 15:4, pages 664-677.
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Inayat B. Pathan, Mahesh Sakhare, Wahid Ambekar & Chitral M. Setty. (2020) Dermal Delivery of Meloxicam Nanosuspensions based Gel: Optimization with Box Behnken Design Experiment Approach: Ex Vivo and In Vivo Study. Nanoscience & Nanotechnology-Asia 10:6, pages 766-777.
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Sameh Hosam Abd El-Alim, Abeer Salama & Asmaa Badawy Darwish. (2020) Provesicular elastic carriers of Simvastatin for enhanced wound healing activity: An in-vitro/in-vivo study. International Journal of Pharmaceutics 585, pages 119470.
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Hesham M. Tawfeek, Ahmed A.H. Abdellatif, Jelan A. Abdel-Aleem, Yasser A. Hassan & Dina Fathalla. (2020) Transfersomal gel nanocarriers for enhancement the permeation of lornoxicam. Journal of Drug Delivery Science and Technology 56, pages 101540.
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Shahira F. El Menshawe, Heba M. Aboud, Mohammed H. Elkomy, Rasha M. Kharshoum & Amany M. Abdeltwab. (2019) A novel nanogel loaded with chitosan decorated bilosomes for transdermal delivery of terbutaline sulfate: artificial neural network optimization, in vitro characterization and in vivo evaluation. Drug Delivery and Translational Research 10:2, pages 471-485.
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Hesham M. Tawfeek, Doaa A. E. Abou-Taleb, Dalia M. Badary, Mohamed Ibrahim & Ahmed A. H. Abdellatif. (2019) Pharmaceutical, clinical, and immunohistochemical studies of metformin hydrochloride topical hydrogel for wound healing application. Archives of Dermatological Research 312:2, pages 113-121.
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Emirhan Nemutlu, İpek Eroğlu, Hakan Eroğlu & Sedef Kır. (2019) In Vitro Release Test of Nano-drug Delivery Systems Based on Analytical and Technological Perspectives. Current Analytical Chemistry 15:4, pages 373-409.
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Amit Verma, Gajanand Sharma, Ankit Jain, Ankita Tiwari, Shivani Saraf, Pritish Kumar Panda, Om Prakash Katare & Sanjay K. Jain. (2019) Systematic optimization of cationic surface engineered mucoadhesive vesicles employing Design of Experiment (DoE): A preclinical investigation. International Journal of Biological Macromolecules 133, pages 1142-1155.
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Sameh Hosam Abd El-Alim, Ahmed Alaa Kassem, Mona Basha & Abeer Salama. (2019) Comparative study of liposomes, ethosomes and transfersomes as carriers for enhancing the transdermal delivery of diflunisal: In vitro and in vivo evaluation. International Journal of Pharmaceutics 563, pages 293-303.
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Heba A. Fathi, Ayat Allam, Mahmoud Elsabahy, Gihan Fetih & Mahmoud El-Badry. (2018) Nanostructured lipid carriers for improved oral delivery and prolonged antihyperlipidemic effect of simvastatin. Colloids and Surfaces B: Biointerfaces 162, pages 236-245.
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Vanesa Andreu & Manuel Arruebo. (2018) Current progress and challenges of nanoparticle-based therapeutics in pain management. Journal of Controlled Release 269, pages 189-213.
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Rabinarayan parhi. (2017) Cross-Linked Hydrogel for Pharmaceutical Applications: A Review. Advanced Pharmaceutical Bulletin 7:4, pages 515-530.
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Ahmed Alaa Kassem, Sameh Hosam Abd El-Alim & Marwa Hasanein Asfour. (2017) Enhancement of 8-methoxypsoralen topical delivery via nanosized niosomal vesicles: Formulation development, in vitro and in vivo evaluation of skin deposition. International Journal of Pharmaceutics 517:1-2, pages 256-268.
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Sayed H. Auda, Dina Fathalla, Gihan Fetih, Mahmoud El-Badry & Faiyaz Shakeel. (2015) Niosomes as transdermal drug delivery system for celecoxib: in vitro and in vivo studies. Polymer Bulletin 73:5, pages 1229-1245.
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