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Original Article

The effects of orchidectomy and supraphysiological testosterone administration on trabecular bone structure and gene expression in rats

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Pages 60-66 | Received 10 Jul 2014, Accepted 11 Aug 2014, Published online: 28 Aug 2014

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Vinícius de Paiva Gonçalves, Adriana Alicia Cabrera-Ortega, Jhonatan de Souza Carvalho, Dania Ramadan & Luís Carlos Spolidorio. (2021) Physiological testosterone replacement effects on male aged rats with orchiectomy-induced osteoporosis in advanced stage: a tomographic and biomechanical pilot study. The Aging Male 24:1, pages 139-147.
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Nur-Vaizura Mohamad, Soelaiman Ima-Nirwana & Kok-Yong Chin. (2020) The effects of gonadotropin-releasing hormone agonist (buserelin) and orchidectomy on bone turnover markers and histomorphometry in rats. The Aging Male 23:5, pages 327-334.
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Sok Kuan Wong, Kok-Yong Chin & Soelaiman Ima-Nirwana. (2019) The Osteoprotective Effects Of Kaempferol: The Evidence From In Vivo And In Vitro Studies. Drug Design, Development and Therapy 13, pages 3497-3514.
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Nur-Vaizura Mohamad, Ima-Nirwana Soelaiman & Kok-Yong Chin. (2016) A concise review of testosterone and bone health. Clinical Interventions in Aging 11, pages 1317-1324.
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A. Khanna. (2023) Effect of resistance exercise on bone health of old aged individuals: Review. Science & Sports 38:4, pages 323-336.
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Bing-na Zhou, Qian Zhang, Xiao-yun Lin, Jing Hu, Di-chen Zhao, Yan Jiang, Xiao-ping Xing & Mei Li. (2022) The roles of sclerostin and irisin on bone and muscle of orchiectomized rats. BMC Musculoskeletal Disorders 23:1.
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Kazuyoshi Shigehara, Kouji Izumi, Yoshifumi Kadono & Atsushi Mizokami. (2021) Testosterone and Bone Health in Men: A Narrative Review. Journal of Clinical Medicine 10:3, pages 530.
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Jing Qiu, Hongxia Gong, Bixin Wang, Weiguo Gu, Lei Wang, Miaomiao Gu, Yuan Zhang & Xiangdong Du. (2020) The use of clozapine is protective for low bone mineral density induced by prolactin-raising antipsychotics in inpatients with schizophrenia. Archives of Osteoporosis 15:1.
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Jian Zhou, Yaping Wei, Yuan Lan, Jingjing Zuo, Xiangqing Hou & Weikai Hou. (2019) Individual and joint association of bioavailable testosterone and aging with neutrophil-to-lymphocyte ratio in Chinese middle-aged and elderly men. Aging Clinical and Experimental Research 32:8, pages 1515-1523.
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Maureen L. Meister, Huanbiao Mo, Xiangming Ji & Chwan‐Li Shen. (2020) Tocotrienols in Bone Protection: Evidence from Preclinical Studies. eFood 1:3, pages 217-225.
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Silvia Colucci & Giacomina Brunetti. 2020. Encyclopedia of Bone Biology. Encyclopedia of Bone Biology 588 594 .
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James Jolly, Kok-Yong Chin, Ekram Alias, Kien Chua & Ima Soelaiman. (2018) Protective Effects of Selected Botanical Agents on Bone. International Journal of Environmental Research and Public Health 15:5, pages 963.
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Chwan-Li Shen, Annika Klein, Kok-Yong Chin, Huanbiao Mo, Peihsuan Tsai, Rong-Sen Yang, Ming-Chien Chyu & Soelaiman Ima-Nirwana. (2017) Tocotrienols for bone health: a translational approach. Annals of the New York Academy of Sciences 1401:1, pages 150-165.
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Vladimir Z. Ajdžanović, Branko R. Filipović, Branka T. Šošić Jurjević & Verica Lj. Milošević. (2017) Testosterone supplementation, glucocorticoid milieu and bone homeostasis in the ageing male. Fundamental & Clinical Pharmacology 31:4, pages 372-382.
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Saranyapin Potikanond, Pinyada Rattanachote, Hiranya Pintana, Panan Suntornsaratoon, Narattaphol Charoenphandhu, Nipon Chattipakorn & Siriporn Chattipakorn. (2016) Obesity does not aggravate osteoporosis or osteoblastic insulin resistance in orchiectomized rats. Journal of Endocrinology 228:2, pages 85-95.
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