1,696
Views
38
CrossRef citations to date
0
Altmetric
Research Article

Synthesis and antioxidant activity evaluations of melatonin-based analogue indole-hydrazide/hydrazone derivatives

, &
Pages 428-436 | Received 23 May 2011, Accepted 01 Jun 2011, Published online: 08 Jul 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Choitanya Dev Pegu, Sheikh Benazir Nasrin, Mohit L. Deb, Deep Jyoti Das, Kandarpa K. Saikia & Pranjal K. Baruah. (2017) CAN-catalyzed microwave promoted reaction of indole with Betti bases under solvent-free condition and evaluation of antibacterial activity of the products. Synthetic Communications 47:21, pages 2007-2014.
Read now
Hanif Shirinzadeh, Elif Ince, Andrew D. Westwell, Hande Gurer-Orhan & Sibel Suzen. (2016) Novel indole-based melatonin analogues substituted with triazole, thiadiazole and carbothioamides: studies on their antioxidant, chemopreventive and cytotoxic activities. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 1312-1321.
Read now
M. Orhan Puskullu, Hanif Shirinzadeh, Merve Nenni, Hande Gurer-Orhan & Sibel Suzen. (2016) Synthesis and evaluation of antioxidant activity of new quinoline-2-carbaldehyde hydrazone derivatives: bioisosteric melatonin analogues. Journal of Enzyme Inhibition and Medicinal Chemistry 31:1, pages 121-125.
Read now
Sibel Suzen, Betul Tekiner-Gulbas, Hanif Shirinzadeh, Duysal Uslu, Hande Gurer-Orhan, Mehmet Gumustas & Sibel Aysil Ozkan. (2013) Antioxidant activity of indole-based melatonin analogues in erythrocytes and their voltammetric characterization. Journal of Enzyme Inhibition and Medicinal Chemistry 28:6, pages 1143-1155.
Read now

Articles from other publishers (34)

Seyit Ali Güngör. (2023) Synthesis, in silico and in vitro studies of hydrazide‐hydrazone imine derivatives as potential cholinesterase inhibitors . Chemical Biology & Drug Design 102:4, pages 676-691.
Crossref
Lei Xie, Hang Wu, Xiaohong Huang & Tengbo Yu. (2023) Melatonin, a natural antioxidant therapy in spinal cord injury. Frontiers in Cell and Developmental Biology 11.
Crossref
Selsabil Djafarou, Arif Mermer, Burak Barut, Gizem Tatar Yılmaz, Imene Amine khodja & Houssem Boulebd. (2023) Synthesis and evaluation of the antioxidant and anti-tyrosinase activities of thiazolyl hydrazone derivatives and their application in the anti-browning of fresh-cut potato. Food Chemistry 414, pages 135745.
Crossref
Sakshi Chaudhary. (2023) SYNTHESIS AND ANTICONVULSANT ACTIVITY OF NEWER BENZOTHIAZINYL / BENZOXAZINYL INDOLES. INDIAN DRUGS 60:04, pages 17-23.
Crossref
Mirna T. Helmy, Farid M. Sroor, Abdelmageed M. Othman, Hamdi M. Hassaneen, Fatma M. Saleh & Mohamed A. Mohamed Teleb. (2022) Design, synthesis and in‐vitro evaluation of new furan‐substituted thiadiazolyl hydrazone derivatives as promising antimicrobial agents . Journal of Heterocyclic Chemistry 60:4, pages 585-595.
Crossref
Sibel Suzen & Luciano Saso. 2023. 249 276 .
Sibel Suzen. 2023. Emerging Anti-Aging Strategies. Emerging Anti-Aging Strategies 155 189 .
Nitin Kumar, Pankaj Gupta & Sahil Bansal. (2022) Progress and Development of Carbazole Scaffold Based as Potential Anti- Alzheimer Agents Using MTDL Approach. Letters in Drug Design & Discovery 19:12, pages 1049-1067.
Crossref
Suzan Alhilal, Mohammad Alhilal, Sobhi M. Gomha & Salama A. Ouf. (2022) Synthesis and biological evaluation of new aza-acyclic nucleosides and their hydrogen complexes from indole. Research on Chemical Intermediates 48:8, pages 3567-3587.
Crossref
Houssem Boulebd, Yasmine Zine, Imene Amine Khodja, Arif Mermer, Adem Demir & Abdelmadjid Debache. (2022) Synthesis and radical scavenging activity of new phenolic hydrazone/hydrazide derivatives: Experimental and theoretical studies. Journal of Molecular Structure 1249, pages 131546.
Crossref
Shaik Ghouse, Chinnabattigalla Sreenivasulu, Dakoju Ravi Kishore & Gedu Satyanarayana. (2022) Recent developments by zinc based reagents/catalysts promoted organic transformations. Tetrahedron 105, pages 132580.
Crossref
Annia Galano, Eduardo G. Guzmán-López & Russel J. Reiter. (2021) Potentiating the Benefits of Melatonin through Chemical Functionalization: Possible Impact on Multifactorial Neurodegenerative Disorders. International Journal of Molecular Sciences 22:21, pages 11584.
Crossref
Ibrahim Mhaidat, Fadel Alwedian, Taher Ababneh, Ayman Shdefat & Hasan Tashtoush. (2021) Synthesis, characterization, computational, antioxidant and fluorescence properties of novel 1,3,5-trimesic hydrazones derivatives. Heliyon 7:9, pages e08074.
Crossref
Imene Amine Khodja & Houssem Boulebd. (2020) Synthesis, biological evaluation, theoretical investigations, docking study and ADME parameters of some 1,4-bisphenylhydrazone derivatives as potent antioxidant agents and acetylcholinesterase inhibitors. Molecular Diversity 25:1, pages 279-290.
Crossref
Sunil Kumar & Ritika. (2020) A brief review of the biological potential of indole derivatives. Future Journal of Pharmaceutical Sciences 6:1.
Crossref
Hanif Shirinzadeh, Eddy Neuhaus, Elif Ince Erguc, Alev Tascioglu Aliyev, Hande Gurer-Orhan & Sibel Suzen. (2020) New indole-7-aldehyde derivatives as melatonin analogues; synthesis and screening their antioxidant and anticancer potential. Bioorganic Chemistry 104, pages 104219.
Crossref
Romina Castañeda-Arriaga, Adriana Pérez-González, Miguel Reina & Annia Galano. (2020) Computer-designed melatonin derivatives: potent peroxyl radical scavengers with no pro-oxidant behavior. Theoretical Chemistry Accounts 139:8.
Crossref
Hanif Shirinzadeh, Mohammed Ghalia, Alev Tascioglu, Ferial Intissar Adjali, Gulsen Gunesacar, Hande Gurer-Orhan & Sibel Suzen. (2020) Bioisosteric modification on melatonin: synthesis of new naphthalene derivatives, in vitro antioxidant activity and cytotoxicity studies. Brazilian Journal of Pharmaceutical Sciences 56.
Crossref
Su-Yan Wang, Xin-Chi Shi & Pedro Laborda. (2020) Indole-based melatonin analogues: Synthetic approaches and biological activity. European Journal of Medicinal Chemistry 185, pages 111847.
Crossref
Edison Osorio, Karent Bravo, Wilson Cardona, Andres Yepes, Edison H. Osorio & Juan C. Coa. (2019) Antiaging activity, molecular docking, and prediction of percutaneous absorption parameters of quinoline–hydrazone hybrids. Medicinal Chemistry Research 28:11, pages 1959-1973.
Crossref
Murat Bingul, Mehmet F. Saglam, Hakan Kandemir, Mehmet Boga & Ibrahim F. Sengul. (2019) Synthesis of indole-2-carbohydrazides and 2-(indol-2-yl)-1,3,4-oxadiazoles as antioxidants and their acetylcholinesterase inhibition properties. Monatshefte für Chemie - Chemical Monthly 150:8, pages 1553-1560.
Crossref
Momin Khan, Umar Ali, Anis Ur Rahman, Muhammad Ibrahim, Abdul Hameed, Muhammad Asif, Zahid Hussain, Kanwal, Khalid Mohammed Khan, Shahnaz Perveen & Munir ur Rehman. (2019) Green Synthesis, Characterization, DPPH and Ferrous Ion-chelating (FIC) Activity of Tetrakis-Schiff’s Bases of Terephthalaldehyde. Letters in Drug Design & Discovery 16:3, pages 249-255.
Crossref
Neda O. Anastassova, Denista Y. Yancheva, Anelia Ts Mavrova, Magdalena S. Kondeva-Burdina, Virginia I. Tzankova, Nadya G. Hristova-Avakumova & Vera A. Hadjimitova. (2018) Design, synthesis, antioxidant properties and mechanism of action of new N,N′-disubstituted benzimidazole-2-thione hydrazone derivatives. Journal of Molecular Structure 1165, pages 162-176.
Crossref
Muafia Jabeen, Sajjad Ahmad, Khadija Shahid, Abdul Sadiq & Umer Rashid. (2018) Ursolic Acid Hydrazide Based Organometallic Complexes: Synthesis, Characterization, Antibacterial, Antioxidant, and Docking Studies. Frontiers in Chemistry 6.
Crossref
Annia Galano, Dun-Xian Tan & Russel Reiter. (2018) Melatonin: A Versatile Protector against Oxidative DNA Damage. Molecules 23:3, pages 530.
Crossref
Sibel Suzen. 2018. Molecular Basis and Emerging Strategies for Anti-aging Interventions. Molecular Basis and Emerging Strategies for Anti-aging Interventions 217 235 .
Annia Galano. (2016) A first principles investigation on the electron donor ability of synthetic melatonin derivatives: implications for their antioxidant activity. Theoretical Chemistry Accounts 135:6.
Crossref
Hande Gurer-Orhan, Cigdem Karaaslan, Senem Ozcan, Omidreza Firuzi, Marjan Tavakkoli, Luciano Saso & Sibel Suzen. (2016) Novel indole-based melatonin analogues: Evaluation of antioxidant activity and protective effect against amyloid β-induced damage. Bioorganic & Medicinal Chemistry 24:8, pages 1658-1664.
Crossref
Annia Galano. (2016) Computational-aided design of melatonin analogues with outstanding multifunctional antioxidant capacity. RSC Advances 6:27, pages 22951-22963.
Crossref
Yara E. El-Shorafa, Daisy H. Fleita, Ola K. Sakka, William T. A. Harrison, Khaled Mahmoud & Rafat M. Mohareb. (2015) Syntheses, crystal structures, in vitro antitumor and free radical scavenging activity evaluation of a series of 2-substituted thiophenes. Medicinal Chemistry Research 24:7, pages 3021-3036.
Crossref
Maria Hr. Vakarelska-Popovska & Zhivko As. Velkov. (2014) Structure of Flavones and Flavonols. Part II: Role of Position on the O-H Bond Dissociation Enthalpy. Computational Chemistry 02:01, pages 1-5.
Crossref
Claudio C. Silveira, Samuel R. Mendes, Josemar R. Soares, Francine N. Victoria, Débora M. Martinez & Lucielli Savegnago. (2013) Synthesis and antioxidant activity of new C-3 sulfenyl indoles. Tetrahedron Letters 54:36, pages 4926-4929.
Crossref
Cigdem Karaaslan, Hachemi Kadri, Tulay Coban, Sibel Suzen & Andrew D. Westwell. (2013) Synthesis and antioxidant properties of substituted 2-phenyl-1H-indoles. Bioorganic & Medicinal Chemistry Letters 23:9, pages 2671-2674.
Crossref
Sibel Suzen, Seyhan Sezen Cihaner & Tulay Coban. (2012) Synthesis and Comparison of Antioxidant Properties of Indole-Based Melatonin Analogue Indole Amino Acid Derivatives. Chemical Biology & Drug Design 79:1, pages 76-83.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.