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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 27, 2012 - Issue 5
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Research Article

Nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity

Shenghui YuDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, PR China
,
Linna ZhangQilu Hospital of Shandong University, Jinan, Shandong, PR China
,
Shifeng YanDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, PR China
,
Peng WangDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, PR China
,
Tino SanchezDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, USA
,
Frauke ChristLaboratory for Molecular Virology and Gene Therapy, Department of Molecular and Cellular Medicine IRC KULAK and KULeuven, Leuven, Flanders, Belgium
,
Zeger DebyserLaboratory for Molecular Virology and Gene Therapy, Department of Molecular and Cellular Medicine IRC KULAK and KULeuven, Leuven, Flanders, Belgium
,
Nouri NeamatiDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, USA
&
Guisen ZhaoDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, PR ChinaCorrespondence[email protected] [email protected]
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Pages 628-640 | Received 16 May 2011, Accepted 10 Jul 2011, Published online: 11 Jan 2012

Citations (3)

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Read on this site (1)

S. Yu, P. Wang, Y. Li, Y. Liu & G. Zhao. (2013) Docking-based CoMFA and CoMSIA study of azaindole carboxylic acid derivatives as promising HIV-1 integrase inhibitors. SAR and QSAR in Environmental Research 24:10, pages 819-839.
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Articles from other publishers (2)

Sirin Uysal, Zeynep Soyer, Merve Saylam, Ayse H. Tarikogullari, Sinem Yilmaz & Petek Ballar Kirmizibayrak. (2021) Design, synthesis and biological evaluation of novel naphthoquinone-4-aminobenzensulfonamide/carboxamide derivatives as proteasome inhibitors. European Journal of Medicinal Chemistry 209, pages 112890.
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Shenghui Yu, Tino Wilson Sanchez, Yang Liu, Yanzhen Yin, Nouri Neamati & Guisen Zhao. (2013) Design and synthesis of novel pyrimidone analogues as HIV-1 integrase inhibitors. Bioorganic & Medicinal Chemistry Letters 23:22, pages 6134-6137.
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