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Research Article

Amelioration of Ochratoxin A-induced immunotoxic effects by silymarin and vitamin E in White Leghorn cockerels

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Pages 25-31 | Received 22 Jan 2012, Accepted 15 Apr 2012, Published online: 26 Jun 2012

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Read on this site (12)

Shaaban S. Elnesr, Hamada A. M. Elwan, Mohamed I. El Sabry & Abdelrazeq M. Shehata. (2023) The nutritional importance of milk thistle (Silybum marianum) and its beneficial influence on poultry. World's Poultry Science Journal 79:4, pages 751-768.
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Muhammad A. Tahir, Asghar Abbas, Muhammad Muneeb, Rana M. Bilal, Kashif Hussain, Abdel-Moneim E. Abdel-Moneim, Mayada R. Farag, Kuldeep Dhama, Shaaban S. Elnesr & Mahmoud Alagawany. (2022) Ochratoxicosis in poultry: occurrence, environmental factors, pathological alterations and amelioration strategies. World's Poultry Science Journal 78:3, pages 727-749.
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Sahar Fanoudi, Mohaddeseh Sadat Alavi, Gholamreza Karimi & Hossein Hosseinzadeh. (2020) Milk thistle (Silybum Marianum) as an antidote or a protective agent against natural or chemical toxicities: a review. Drug and Chemical Toxicology 43:3, pages 240-254.
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Aisha Khatoon & Zain ul Abidin. (2020) Mycotoxicosis – diagnosis, prevention and control: past practices and future perspectives. Toxin Reviews 39:2, pages 99-114.
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Lidia Radko & Wojciech Cybulski. (2019) The decrease of lasalocid residue in the edible tissues by silymarin supplementation of chicken diet. Food Additives & Contaminants: Part A 36:5, pages 722-728.
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Aisha Khatoon, Muhammad Zargham Khan, Zain ul Abidin & Sheraz Ahmed Bhatti. (2018) Effects of feeding bentonite clay upon ochratoxin A–induced immunosuppression in broiler chicks. Food Additives & Contaminants: Part A 35:3, pages 538-545.
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Ahrar Khan, Muhammad Mustjab Aalim, Muhammad Zargham Khan, M. Kashif Saleemi, Cheng He, Aisha Khatoon & Shafia Tehseen Gul. (2017) Amelioration of immunosuppressive effects of aflatoxin and ochratoxin A in White Leghorn layers with distillery yeast sludge. Toxin Reviews 36:4, pages 275-281.
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Z. Abidin, A. Khatoon, N. Arooj, S. Hussain, S. Ali, A. W. Manzoor & M. K. Saleemi. (2017) Estimation of ochratoxin A in poultry feed and its ingredients with special reference to temperature conditions. British Poultry Science 58:3, pages 251-255.
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Sheraz Ahmed Bhatti, Muhammad Zargham Khan, Muhammad Kashif Saleemi, Muhammad Saqib, Ahrar Khan & Zahoor ul-Hassan. (2017) Protective role of bentonite against aflatoxin B1- and ochratoxin A-induced immunotoxicity in broilers. Journal of Immunotoxicology 14:1, pages 66-76.
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Zain ul Abidin, Muhammad Zargham Khan, Aisha Khatoon, Muhammad Kashif Saleemi & Ahrar Khan. (2016) Protective effects of l-carnitine upon toxicopathological alterations induced by ochratoxin A in white Leghorn cockerels. Toxin Reviews 35:3-4, pages 157-164.
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Daniela E. Marin & Ionelia Taranu. (2015) Ochratoxin A and its effects on immunity. Toxin Reviews 34:1, pages 11-20.
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Aisha Khatoon, Muhammad Yasir Nawaz, Ghazala Mehboob, Muhammad Kashif Saleemi, Shafia Tehseen Gul, Rao Zahid Abbas, Muhammad Umar Ijaz, Bilal Murtaza, Sheraz Ahmed Bhatti, Zain ul Abidin & Aamir Riaz Khan. (2023) Unraveling the combined deleterious effects of ochratoxin A and atrazine upon broiler’s health: Toxicopathological, serum biochemical and immunological perspectives. Toxicon 236, pages 107327.
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Alexandra M. QuinnSteven Sandberg-Lewis. (2023) Challenging Case in Clinical Practice: Identification and Treatment of Mycotoxin Illness Using an Environmental Medicine Perspective. Integrative and Complementary Therapies 29:5, pages 232-238.
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Blessing A. Obafemi, Isaac A. Adedara & Joao B.T. Rocha. (2023) Neurotoxicity of ochratoxin A: Molecular mechanisms and neurotherapeutic strategies. Toxicology 497-498, pages 153630.
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Alessandro Guerrini & Doriana Eurosia Angela Tedesco. (2023) Restoring Activity of Milk Thistle (Silybum marianum L.) on Serum Biochemical Parameters, Oxidative Status, Immunity, and Performance in Poultry and Other Animal Species, Poisoned by Mycotoxins: A Review. Animals 13:3, pages 330.
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Peter F. Surai. 2023. Molecular Nutrition and Mitochondria. Molecular Nutrition and Mitochondria 535 559 .
Mian Muhammad Awais, Ujala Mehtab, Muhammad Irfan Anwar, Muhammad Raza Hameed, Masood Akhtar, Ahmad Raza, Riffat Aisha, Faqir Muhammad, Muhammad Kashif Saleemi & Ahad Fayyaz. (2022) Mitigation potential of individual and combined dietary supplementation of local Bentonite Clay and Distillery Sludge against Ochratoxin-A induced toxicity in broilers. BMC Veterinary Research 18:1.
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Sadaf SHAKOOR, Amin ISMAIL, Mohd Redzwan SABRAN, Norhafizah MOHTARRUDIN, Ubedullah KAKA & Muhammad NADEEM. (2022) In-vivo study of synthetic and natural food colors effect on biochemical and immunity parameters. Food Science and Technology 42.
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Ramesh C. Gupta, Robin B. Doss, Rajiv Lall, Ajay Srivastava & Anita Sinha. 2022. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 983 1002 .
Ashiq Ali, Aisha Khatoon, Muhammad Kashif Saleemi & Rao Zahid Abbas. (2021) Aflatoxins associated oxidative stress and immunological alterations are mitigated by dietary supplementation of Pichia kudriavzevii in broiler chicks. Microbial Pathogenesis 161, pages 105279.
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Kamila Bechynska, Vit Kosek, Marie Fenclova, Lucie Muchova, Vaclav Smid, Jakub Suk, Karel Chalupsky, Eva Sticova, Kamila Hurkova, Jana Hajslova, Libor Vitek & Milena Stranska. (2021) The Effect of Mycotoxins and Silymarin on Liver Lipidome of Mice with Non-Alcoholic Fatty Liver Disease. Biomolecules 11:11, pages 1723.
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Sara Shahba, Jalil Mehrzad & Amir Mohammad Malvandi. (2021) Neuroimmune disruptions from naturally occurring levels of mycotoxins. Environmental Science and Pollution Research 28:25, pages 32156-32176.
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Olga Bagno, Sergey Shevchenko, Antonina Shevchenko, Oleg Prokhorov, Anna Shentseva, Grigory Vavin & Elena Ulrich. (2021) Physiological status of broiler chickens with diets supplemented with milk thistle extract. Veterinary World, pages 1319-1323.
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Pauline Christ Ledur & Janio M. Santurio. (2020) Cytoprotective effects of curcumin and silymarin on PK-15 cells exposed to ochratoxin A, fumonisin B1 and deoxynivalenol. Toxicon 185, pages 97-103.
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SATYENDRA SINGH, RAM SINGH & A B MANDAL. (2019) Associated efficiency of Saccharomyces cerevisiae and vitamin E in ameliorating adverse effects of ochratoxin A on biochemical profile and immune response in broiler chickens. The Indian Journal of Animal Sciences 89:5.
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Dandan Liu, Jiarui Su, Jiashan Lin, Gang Qian, Xingxiang Chen, Suquan Song & Kehe Huang. (2018) Activation of AMPK-dependent SIRT-1 by astragalus polysaccharide protects against ochratoxin A-induced immune stress in vitro and in vivo. International Journal of Biological Macromolecules 120, pages 683-692.
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Sheraz Ahmed Bhatti, Muhammad Zargham Khan, Zahoor Ul Hassan, Muhammad Kashif Saleemi, Aisha Khatoon, Zain ul Abidin & Muhammad Raza Hameed. (2018) Dietary L-carnitine and vitamin-E; a strategy to combat ochratoxin-A induced immunosuppression. Toxicon 153, pages 62-71.
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Lili Hou, Xuan Zhou, Fang Gan, Zixuan Liu, Yajiao Zhou, Gang Qian & Kehe Huang. (2018) Combination of Selenomethionine and N -Acetylcysteine Alleviates the Joint Toxicities of Aflatoxin B1 and Ochratoxin A by ERK MAPK Signal Pathway in Porcine Alveolar Macrophages . Journal of Agricultural and Food Chemistry 66:23, pages 5913-5923.
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Ramesh C. Gupta, Ajay Srivastava & Rajiv Lall. 2018. Veterinary Toxicology. Veterinary Toxicology 1019 1027 .
A. KhatoonM.Z. KhanZ. AbidinA. KhanM.K. Saleemi. (2017) Mitigation potential of distillery sludge against ochratoxin A induced immunological alterations in broiler chicks. World Mycotoxin Journal 10:3, pages 255-262.
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Ramesh C. Gupta, Michelle A. Lasher, Ida R. Miller Mukherjee, Ajay Srivastava & Rajiv Lall. 2017. Reproductive and Developmental Toxicology. Reproductive and Developmental Toxicology 945 962 .
MOHIT SINGH, RAM SINGH, A B MANDAL & MAMTA SHARMA. (2016) Influence of dietary supplementation of vitamin E in ameliorating adverse effects of ochratoxin on biochemical profile and immune response in broiler chickens. The Indian Journal of Animal Sciences 86:12.
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Peter F. Surai, Vladimir I. Fisinin & Filiz Karadas. (2016) Antioxidant systems in chick embryo development. Part 1. Vitamin E, carotenoids and selenium. Animal Nutrition 2:1, pages 1-11.
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