7,511
Views
98
CrossRef citations to date
0
Altmetric
Review Articles

Porphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer’s disease

, &
Article: 33029 | Received 31 Jul 2016, Accepted 21 Oct 2016, Published online: 22 Nov 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Caroline A. de Jongh, Teun J. de Vries, Floris J. Bikker, Susan Gibbs & Bastiaan P. Krom. (2023) Mechanisms of Porphyromonas gingivalis to translocate over the oral mucosa and other tissue barriers. Journal of Oral Microbiology 15:1.
Read now
Qiong Ma, Xueke Li, Hua Jiang, Xi Fu, Liting You, Fengming You & Yifeng Ren. (2023) Mechanisms underlying the effects, and clinical applications, of oral microbiota in lung cancer: current challenges and prospects. Critical Reviews in Microbiology 0:0, pages 1-22.
Read now
Jihei Sara Lee, Sangchul Yoon, Soo Jung Han, Eun-Do Kim, Jiyeon Kim, Hae-Sol Shin & Kyoung Yul Seo. (2022) Eyedrop vaccination: an immunization route with promises for effective responses to pandemics. Expert Review of Vaccines 21:1, pages 91-101.
Read now
Ingar Olsen. (2021) Possible effects of Porphyromonas gingivalis on the blood–brain barrier in Alzheimer’s disease. Expert Review of Anti-infective Therapy 19:11, pages 1367-1371.
Read now
Kenji Matsushita, Masae Yamada-Furukawa, Mie Kurosawa & Yosuke Shikama. (2020) Periodontal Disease and Periodontal Disease-Related Bacteria Involved in the Pathogenesis of Alzheimer’s Disease. Journal of Inflammation Research 13, pages 275-283.
Read now
Ingar Olsen & Özlem Yilmaz. (2019) Possible role of Porphyromonas gingivalis in orodigestive cancers. Journal of Oral Microbiology 11:1.
Read now
Ingar Olsen, Sim K. Singhrao & Jan Potempa. (2018) Citrullination as a plausible link to periodontitis, rheumatoid arthritis, atherosclerosis and Alzheimer’s disease. Journal of Oral Microbiology 10:1.
Read now
Ingar Olsen, John D. Lambris & George Hajishengallis. (2017) Porphyromonas gingivalis disturbs host–commensal homeostasis by changing complement function. Journal of Oral Microbiology 9:1.
Read now
Ingar Olsen, Sim K. Singhrao & Harald Osmundsen. (2017) Periodontitis, pathogenesis and progression: miRNA-mediated cellular responses to Porphyromonas gingivalis. Journal of Oral Microbiology 9:1.
Read now

Articles from other publishers (87)

Christine Zürcher & Christian Humpel. (2023) Saliva: a challenging human fluid to diagnose brain disorders with a focus on Alzheimer’s disease. Neural Regeneration Research 18:12, pages 2606-2610.
Crossref
O. A. Gonzalez, S. Kirakodu, L. Nguyen & J. L. Ebersole. (2023) Macrophage‐related gingival transcriptomic patterns and microbiome alterations in experimental periodontitis in nonhuman primates. Journal of Periodontal Research 58:6, pages 1148-1170.
Crossref
Cristhiam de J.  Hernández Martínez, Pedro  Felix Silva, Sergio L. Salvador, Michel Messora & Daniela B. Palioto. (2023) Chronological analysis of periodontal bone loss in experimental periodontitis in mice. Clinical and Experimental Dental Research.
Crossref
Omar M Warsi, Lars Gedda, Katarina Edwards & Dan I Andersson. (2023) Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities. FEMS Microbiology Ecology 99:12.
Crossref
Brian A. Kleiboeker, Cheryl Frankfater, Mary E. Davey & Fong-Fu Hsu. (2023) Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl- and phosphoglycerol dipeptide lipid families. Journal of Lipid Research, pages 100470.
Crossref
Lan Yang, Jiaxuan Wu, Guocheng Mei, Qiaozhi Jiang, Zhiheng Su, Haiqing Liao, Zhenmin Liu, Renchuan Tao & Xiangzhi Yong. (2023) Corydalis Saxicola Bunting Total Alkaloid Eliminates Porphyromonas gingivalis strain 33277 Internalized into Macrophages by Inhibition of TLR2. Microbes and Infection, pages 105244.
Crossref
Xiu-Li Wang, Hua-Wen Xu & Ning-Ning Liu. (2023) Oral Microbiota: A New Insight into Cancer Progression, Diagnosis and Treatment. Phenomics 3:5, pages 535-547.
Crossref
Qiong Ma, Xiao Zeng, Xueke Li, Liting You, Xi Fu, Fengming You & Yifeng Ren. (2023) Current status and prospects of the relationship between oral microbiome and the occurrence and development of lung cancer. Chinese Science Bulletin.
Crossref
Nahoko Kato-Kogoe, Kuniyasu Kamiya, Shoichi Sakaguchi, Michi Omori, Eri Komori, Asako Kudo, Shota Nakamura, Takashi Nakano, Takaaki Ueno, Junko Tamaki & Masaaki Hoshiga. (2023) Salivary Microbiota Associated with Peripheral Microvascular Endothelial Dysfunction. Journal of Atherosclerosis and Thrombosis 30:7, pages 820-833.
Crossref
Yuexiang Li, Yunfeng Ma, Jianan Yu, Cancan Li, Da Yu, Ruoxi Dai, Quanli Li & Chris Ying Cao. (2023) A dual functional polypeptide with antibacterial and anti-inflammatory properties for the treatment of periodontitis. International Journal of Biological Macromolecules 242, pages 124920.
Crossref
Yan Xuan, Cai Yu, Kang Ni, Lou Congcong, Qiu Lixin & Luan Qingxian. (2023) Protective Effects of Tanshinone IIA on Porphyromonas gingivalis-induced Atherosclerosis via the Downregulation of the NOX2/NOX4-ROS Mediation of NF-κB Signaling Pathway. Microbes and Infection, pages 105177.
Crossref
Ru Jin, Xiaoqiao Ning, Xiang Liu, Yueyang Zhao & Guo Ye. (2023) Porphyromonas gingivalis-induced periodontitis could contribute to cognitive impairment in Sprague–Dawley rats via the P38 MAPK signaling pathway. Frontiers in Cellular Neuroscience 17.
Crossref
Najwane Said-Sadier, Batoul Sayegh, Raymond Farah, Linda Abou Abbas, Rania Dweik, Norina Tang & David M. Ojcius. (2023) Association between Periodontal Disease and Cognitive Impairment in Adults. International Journal of Environmental Research and Public Health 20:6, pages 4707.
Crossref
Xiaowei Liu, Lei Yang & Xuelian Tan. (2023) PD-1/PD-L1 pathway: A double-edged sword in periodontitis. Biomedicine & Pharmacotherapy 159, pages 114215.
Crossref
Myongin Oh & Donald F. Weaver. (2023) Alzheimer’s disease as a fundamental disease of information processing systems: An information theory perspective. Frontiers in Neuroscience 17.
Crossref
Nadya Lumelsky. (2023) Oral-systemic immune axis: Crosstalk controlling health and disease. Frontiers in Dental Medicine 3.
Crossref
Andrea Quagliariello, Alessandra Modi, Gabriel Innocenti, Valentina Zaro, Cecilia Conati Barbaro, Annamaria Ronchitelli, Francesco Boschin, Claudio Cavazzuti, Elena Dellù, Francesca Radina, Alessandra Sperduti, Luca Bondioli, Stefano Ricci, Miriam Lognoli, Maria Giovanna Belcastro, Valentina Mariotti, David Caramelli, Marta Mariotti Lippi, Emanuela Cristiani, Maria Elena Martino, Italo Maria Muntoni & Martina Lari. (2022) Ancient oral microbiomes support gradual Neolithic dietary shifts towards agriculture. Nature Communications 13:1.
Crossref
Cheng Li, Ran Yu & Yumei Ding. (2022) Association between Porphyromonas Gingivalis and systemic diseases: Focus on T cells-mediated adaptive immunity. Frontiers in Cellular and Infection Microbiology 12.
Crossref
Mark Stasiewicz & Tomasz M. Karpiński. (2022) The oral microbiota and its role in carcinogenesis. Seminars in Cancer Biology 86, pages 633-642.
Crossref
Mark I. Ryder. (2022) The Link Between Periodontitis and Alzheimer’s Disease: Reality or Yet Another Association. Current Oral Health Reports 9:4, pages 157-166.
Crossref
Shalini Kanagasingam, Christopher von Ruhland, Richard Welbury, Sasanka S. Chukkapalli & Sim K. Singhrao. (2022) Porphyromonas gingivalis Conditioned Medium Induces Amyloidogenic Processing of the Amyloid-β Protein Precursor upon in vitro Infection of SH-SY5Y Cells. Journal of Alzheimer's Disease Reports 6:1, pages 577-587.
Crossref
Yajun Shi, Bin Wei, Lingjun Li, Bin Wang & Miao Sun. (2022) Th17 cells and inflammation in neurological disorders: Possible mechanisms of action. Frontiers in Immunology 13.
Crossref
Jason D. Maarsingh, Paweł Łaniewski & Melissa M. Herbst-Kralovetz. (2022) Immunometabolic and potential tumor-promoting changes in 3D cervical cell models infected with bacterial vaginosis-associated bacteria. Communications Biology 5:1.
Crossref
Xiao Han, Junling Ren, Hannah Lohner, Lan Yakoumatos, Ruqiang Liang & Huizhi Wang. (2022) SGK1 negatively regulates inflammatory immune responses and protects against alveolar bone loss through modulation of TRAF3 activity. Journal of Biological Chemistry 298:6, pages 102036.
Crossref
Mihai S. Cirstea, Daniel Kliger, Abbey D. MacLellan, Adam C. Yu, Jenna Langlois, Mannie Fan, Seti Boroomand, Faezeh Kharazyan, Robin G.Y. Hsiung, Brian A. MacVicar, Howard Chertkow, Victor Whitehead, B. Brett Finlay & Silke Appel-Cresswell. (2022) The Oral and Fecal Microbiota in a Canadian Cohort of Alzheimer’s Disease. Journal of Alzheimer's Disease 87:1, pages 247-258.
Crossref
Kuo-Shyang Jeng, Chiung-Fang Chang, I-Shyan Sheen, Chi-Juei Jeng & Chih-Hsuan Wang. (2022) Upper Gastrointestinal Cancer and Liver Cirrhosis. Cancers 14:9, pages 2269.
Crossref
Shiyue Liu, Ya-nan Wang, Lu Yu, Jianhua Li & Shaohua Ge. (2022) Development of a thermosensitive hydrogel loaded with DTT and SDF-1 facilitating in situ periodontal bone regeneration. Chemical Engineering Journal 432, pages 134308.
Crossref
Yan Zhang, Shuang Song, Haitao Li, Xinyan Wang, Lianlian Song & Jianfei Xue. (2022) Polysaccharide from Ganoderma lucidum alleviates cognitive impairment in a mouse model of chronic cerebral hypoperfusion by regulating CD4 + CD25 + Foxp3 + regulatory T cells . Food & Function 13:4, pages 1941-1952.
Crossref
Jia Liu, Xiaoxuan Wang, Fei Xue, Ming Zheng & Qingxian Luan. (2021) Abnormal mitochondrial structure and function are retained in gingival tissues and human gingival fibroblasts from patients with chronic periodontitis. Journal of Periodontal Research 57:1, pages 94-103.
Crossref
Hang Zou, Niu Zhou, Yilian Huang, Aoxiang Luo & Jianbo Sun. (2022) Phenotypes, roles, and modulation of regulatory lymphocytes in periodontitis and its associated systemic diseases. Journal of Leukocyte Biology 111:2, pages 451-467.
Crossref
Maja Ptasiewicz, Ewelina Grywalska, Paulina Mertowska, Izabela Korona-Głowniak, Agata Poniewierska-Baran, Paulina Niedźwiedzka-Rystwej & Renata Chałas. (2022) Armed to the Teeth—The Oral Mucosa Immunity System and Microbiota. International Journal of Molecular Sciences 23:2, pages 882.
Crossref
Biaolong Deng, Weiqi Zhang, Yicheng Zhu, Yangyang Li, Dan Li & Bin Li. (2021) FOXP3 + regulatory T cells and age‐related diseases . The FEBS Journal 289:2, pages 319-335.
Crossref
Steeve Bregaint, Emile Boyer, Shao Bing Fong, Vincent Meuric, Martine Bonnaure-Mallet & Anne Jolivet-Gougeon. (2021) Porphyromonas gingivalis outside the oral cavity. Odontology 110:1, pages 1-19.
Crossref
Chenyu Chu, Xiwen Zhao, Shengan Rung, Wenlan Xiao, Li Liu, Yili Qu & Yi Man. (2021) Application of biomaterials in periodontal tissue repair and reconstruction in the presence of inflammation under periodontitis through the foreign body response: Recent progress and perspectives. Journal of Biomedical Materials Research Part B: Applied Biomaterials 110:1, pages 7-17.
Crossref
Jiaqi Zhang, Mengru Xie, Xiaofei Huang, Guangjin Chen, Ying Yin, Xiaofeng Lu, Guangxia Feng, Ran Yu & Lili Chen. (2021) The Effects of Porphyromonas gingivalis on Atherosclerosis-Related Cells. Frontiers in Immunology 12.
Crossref
Minoru Sasaki, Yu Shimoyama, Yoshitoyo Kodama & Taichi Ishikawa. (2021) Tryptophanyl tRNA Synthetase from Human Macrophages Infected by Porphyromonas gingivalis Induces a Proinflammatory Response Associated with Atherosclerosis. Pathogens 10:12, pages 1648.
Crossref
Xida Zhao, Jingbo Liu, Chong Zhang, Ning Yu, Ze Lu, Shuwei Zhang, Yuchao Li, Qian Li, Junchao Liu, Dongjuan Liu & Yaping Pan. (2021) Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase. International Journal of Oral Science 13:1.
Crossref
Yan Zhang, Xinyan Wang, Xiaomei Yang, Xiudong Yang, Jianfei Xue & Yanjun Yang. (2021) Ganoderic Acid A To Alleviate Neuroinflammation of Alzheimer’s Disease in Mice by Regulating the Imbalance of the Th17/Tregs Axis. Journal of Agricultural and Food Chemistry 69:47, pages 14204-14214.
Crossref
Atefe Ghamar Talepoor, Banafsheh Rastegari, Mehdi Kalani & Mehrnoosh Doroudchi. (2021) Decrease in the inflammatory cytokines of LPS-stimulated PBMCs of patients with atherosclerosis by a TLR-4 antagonist in the co-culture with HUVECs. International Immunopharmacology 101, pages 108295.
Crossref
Erin C. Mooney, Sara E. Holden, Xia-Juan Xia, Yajie Li, Min Jiang, Camille N. Banson, Bin Zhu & Sinem Esra Sahingur. (2021) Quercetin Preserves Oral Cavity Health by Mitigating Inflammation and Microbial Dysbiosis. Frontiers in Immunology 12.
Crossref
Hirohiko Okamura, Katsuhiko Hirota, Kaya Yoshida, Yao Weng, Yuhan He, Noriko Shiotsu, Mika Ikegame, Yoko Uchida-Fukuhara, Airi Tanai & Jiajie Guo. (2021) Outer membrane vesicles of Porphyromonas gingivalis: Novel communication tool and strategy. Japanese Dental Science Review 57, pages 138-146.
Crossref
Wenlei Yu, Linjie Lu, Xintong Ji, Qiwei Qian, Xiaohan Lin & Huanhuan Wang. (2021) Recent Advances on Possible Association Between the Periodontal Infection of Porphyromonas gingivalis and Central Nervous System Injury. Journal of Alzheimer's Disease 84:1, pages 51-59.
Crossref
Mark I. Ryder & Pinelopi Xenoudi. (2021) Alzheimer disease and the periodontal patient: New insights, connections, and therapies. Periodontology 2000 87:1, pages 32-42.
Crossref
Abdelrahman Elwishahy, Khatia Antia, Sneha Bhusari, Nkorika Chiamaka Ilechukwu, Olaf Horstick & Volker Winkler. (2021) Porphyromonas Gingivalis as a Risk Factor to Alzheimer’s Disease: A Systematic Review. Journal of Alzheimer's Disease Reports 5:1, pages 721-732.
Crossref
Mark Stasiewicz, Marek Kwaśniewski & Tomasz M. Karpiński. (2021) Microbial Associations with Pancreatic Cancer: A New Frontier in Biomarkers. Cancers 13:15, pages 3784.
Crossref
Anne O. Rice. (2021) Alzheimer's Disease and Oral-Systemic Health: Bidirectional Care Integration Improving Outcomes. Frontiers in Oral Health 2.
Crossref
Junling Ren, Xiao Han, Hannah Lohner, Ruqiang Liang, Shuang Liang & Huizhi Wang. (2021) Serum- and Glucocorticoid-Inducible Kinase 1 Promotes Alternative Macrophage Polarization and Restrains Inflammation through FoxO1 and STAT3 Signaling. The Journal of Immunology 207:1, pages 268-280.
Crossref
Kübra Bunte, Christina Kuhn, Carolin Walther, Ulrike Peters, Ghazal Aarabi, Ralf Smeets & Thomas Beikler. (2021) Clinical significance of ragA , ragB , and PG0982 genes in Porphyromonas gingivalis isolates from periodontitis patients . European Journal of Oral Sciences 129:3.
Crossref
Kang-Woon Lee, Jae-Goo Kim, Karpagam Veerappan, Hoyong Chung, Sathishkumar Natarajan, Ki-Young Kim & Junhyung Park. (2021) Utilizing Red Spotted Apollo Butterfly Transcriptome to Identify Antimicrobial Peptide Candidates against Porphyromonas gingivalis. Insects 12:5, pages 466.
Crossref
Grigorios Plemmenos, Evangelos Evangeliou, Nikolaos Polizogopoulos, Andreas Chalazias, Marianthi Deligianni & Christina Piperi. (2021) Central Regulatory Role of Cytokines in Periodontitis and Targeting Options. Current Medicinal Chemistry 28:15, pages 3032-3058.
Crossref
Garth D. Ehrlich. (2021) A Trove of Original Treasures. Genetic Testing and Molecular Biomarkers 25:5, pages 307-308.
Crossref
Ingar Olsen. (2021) Can Porphyromonas gingivalis Contribute to Alzheimer’s Disease Already at the Stage of Gingivitis?. Journal of Alzheimer's Disease Reports 5:1, pages 237-241.
Crossref
Jinyu Kong, Xiang Yuan, Jian Wang, Yiwen Liu, Wei Sun, Bianli Gu, Zijun Lan & Shegan Gao. (2021) Frequencies of Porphyromonas gingivalis Detection in Oral-Digestive Tract Tumors. Pathology and Oncology Research 27.
Crossref
Cher Farrugia, Graham P. Stafford, Jan Potempa, Robert N. Wilkinson, Yan Chen, Craig Murdoch & Magdalena Widziolek. (2020) Mechanisms of vascular damage by systemic dissemination of the oral pathogen Porphyromonas gingivalis . The FEBS Journal 288:5, pages 1479-1495.
Crossref
Sarah Myers, Thuy Do, Josephine L. Meade, Aradhna Tugnait, Jon J. Vernon, Jelena Pistolic, Robert E. W. Hancock, Philip D. Marsh, Harsh M. Trivedi, Dandan Chen & Deirdre A. Devine. (2021) Immunomodulatory streptococci that inhibit CXCL8 secretion and NFκB activation are common members of the oral microbiota. Journal of Medical Microbiology 70:3.
Crossref
Maki Nakagawa, Michihiro Shirasugi, Toshiro Yamamoto, Takaaki Nakaya & Narisato Kanamura. (2021) Long-term exposure to butyric acid induces excessive production of matrix metalloproteases in human gingival fibroblasts. Archives of Oral Biology 123, pages 105035.
Crossref
Kazuyoshi Kawahara. (2021) Variation, Modification and Engineering of Lipid A in Endotoxin of Gram-Negative Bacteria. International Journal of Molecular Sciences 22:5, pages 2281.
Crossref
Ingar Olsen. (2021) Porphyromonas Gingivalis May Seek the Alzheimer’s Disease Brain to Acquire Iron from Its Surplus. Journal of Alzheimer's Disease Reports 5:1, pages 79-86.
Crossref
D. S. Shlykova, V. M. Pisarev, A. M. Gaponov & A. V. Tutelyan. (2021) Interaction of bacterial extracellular microvesicles with eukaryotic cells.. Medical Immunology (Russia) 22:6, pages 1065-1084.
Crossref
CitraFeriana Putri & EndangWiniati Bachtiar. (2021) Infection of Porphyromonas gingivalis in Alzheimer’s Disease and the Suppression of Immunity. Dental Hypotheses 12:4, pages 174.
Crossref
Yiwen Liu, Xiang Yuan, Kuisheng Chen, Fuyou Zhou, Haijun Yang, Hong Yang, Yijun Qi, Jinyu Kong, Wei Sun & Shegan Gao. (2021) Clinical significance and prognostic value of Porphyromonas gingivalis infection in lung cancer. Translational Oncology 14:1, pages 100972.
Crossref
Hans Förstl & Sophia Förstl. 2021. Prävention und Gesundheitsförderung. Prävention und Gesundheitsförderung 905 931 .
Lina J. Suárez, Hernan Garzón, Silie Arboleda & Adriana Rodríguez. (2020) Oral Dysbiosis and Autoimmunity: From Local Periodontal Responses to an Imbalanced Systemic Immunity. A Review. Frontiers in Immunology 11.
Crossref
Feng Mei, Mengru Xie, Xiaofei Huang, Yanlin Long, Xiaofeng Lu, Xiaoli Wang & Lili Chen. (2020) Porphyromonas gingivalis and Its Systemic Impact: Current Status. Pathogens 9:11, pages 944.
Crossref
Christian Bailly. (2020) The implication of the PD-1/PD-L1 checkpoint in chronic periodontitis suggests novel therapeutic opportunities with natural products. Japanese Dental Science Review 56:1, pages 90-96.
Crossref
Jean-Paul Rocca, Carlo Fornaini, Zuomin Wang, Lixin Tan & Elisabetta Merigo. (2020) Focal Infection and Periodontitis: A Narrative Report and New Possible Approaches. International Journal of Microbiology 2020, pages 1-9.
Crossref
Ruben Aquino-Martinez, Sundeep Khosla, Joshua N. Farr & David G. Monroe. (2020) Periodontal Disease and Senescent Cells: New Players for an Old Oral Health Problem?. International Journal of Molecular Sciences 21:20, pages 7441.
Crossref
J. Tian, C. Liu, X. Zheng, X. Jia, X. Peng, R. Yang, X. Zhou & X. Xu. (2020) Porphyromonas gingivalis Induces Insulin Resistance by Increasing BCAA Levels in Mice . Journal of Dental Research 99:7, pages 839-846.
Crossref
Friedrich Leblhuber, Kostja Steiner, Simon Geisler, Dietmar Fuchs & Johanna M. Gostner. (2020) On the Possible Relevance of Bottom-up Pathways in the Pathogenesis of Alzheimer’s Disease. Current Topics in Medicinal Chemistry 20:15, pages 1415-1421.
Crossref
Shouchao Wei, Wanjuan Peng, Yingren Mai, Kanglan Li, Wei Wei, Li Hu, Shaoping Zhu, Haihong Zhou, Wanxin Jie, Zhuangsheng Wei, Chenyao Kang, Ruikai Li, Zhou Liu, Bin Zhao & Zhiyou Cai. (2019) Outer membrane vesicles enhance tau phosphorylation and contribute to cognitive impairment. Journal of Cellular Physiology 235:5, pages 4843-4855.
Crossref
José Antonio Gil Montoya, Rocío Barrios, Inés Sanchez‐Lara, Pablo Ramos, Cristobal Carnero, Francisco Fornieles, Juan Montes, Soraya Santana, Juan de Dios Luna & Miguel Angel Gonzalez‐Moles. (2019) Systemic inflammatory impact of periodontitis on cognitive impairment. Gerodontology 37:1, pages 11-18.
Crossref
Yuta Manabe. (2020) In the face of the serious fact that there are 4,620,000 patients diagnosed as having dementia in Japan認知症462万人時代の実際. Annals of Japan Prosthodontic Society 12:2, pages 122-128.
Crossref
Hans Förstl & Sophia Förstl. 2020. Prävention und Gesundheitsförderung. Prävention und Gesundheitsförderung 1 28 .
Eun‐Chong Han, Song‐Yi Choi, Youngkyun Lee, Jin‐Woo Park, Su‐Hyung Hong & Heon‐Jin Lee. (2019) Extracellular RNAs in periodontopathogenic outer membrane vesicles promote TNF‐α production in human macrophages and cross the blood‐brain barrier in mice. The FASEB Journal 33:12, pages 13412-13422.
Crossref
Xiang Yuan, Yiwen Liu, Guifang Li, Zijun Lan, Mingyang Ma, Huaxu Li, Jinyu Kong, Jiangtao Sun, Gaochao Hou, Xurong Hou, Yingjian Ma, Feng Ren, Fuyou Zhou & Shegan Gao. (2019) Blockade of Immune-Checkpoint B7-H4 and Lysine Demethylase 5B in Esophageal Squamous Cell Carcinoma Confers Protective Immunity against P. gingivalis Infection . Cancer Immunology Research 7:9, pages 1440-1456.
Crossref
Jialiang Yu, Yusheng Lin, Xiao Xiong, Kai Li, Zhimeng Yao, Hongmei Dong, Zuojie Jiang, Dan Yu, Sai-Ching Jim Yeung & Hao Zhang. (2019) Detection of Exosomal PD-L1 RNA in Saliva of Patients With Periodontitis. Frontiers in Genetics 10.
Crossref
Sim K. Singhrao, Sarita Robinson & Alice Harding. 2019. Trends in Personalized Nutrition. Trends in Personalized Nutrition 81 104 .
Toshi Horie, Megumi Inomata & Takeshi Into. (2018) OmpA-Like Proteins of Porphyromonas gingivalis Mediate Resistance to the Antimicrobial Peptide LL-37 . Journal of Pathogens 2018, pages 1-7.
Crossref
Sim K. Singhrao & Ingar Olsen. (2018) Are Porphyromonas gingivalis Outer Membrane Vesicles Microbullets for Sporadic Alzheimer’s Disease Manifestation?. Journal of Alzheimer's Disease Reports 2:1, pages 219-228.
Crossref
Hiba Mohammed, Elena Varoni, Andrea Cochis, Massimo Cordaro, Patrizia Gallenzi, Romeo Patini, Edoardo Staderini, Carlo Lajolo, Lia Rimondini & Vincenzo Rocchetti. (2018) Oral Dysbiosis in Pancreatic Cancer and Liver Cirrhosis: A Review of the Literature. Biomedicines 6:4, pages 115.
Crossref
Megumi Inomata, Toshi Horie & Takeshi Into. (2018) OmpA-like proteins of Porphyromonas gingivalis contribute to serum resistance and prevent Toll-like receptor 4-mediated host cell activation. PLOS ONE 13:8, pages e0202791.
Crossref
Tamas Fulop, Jacek M. Witkowski, Karine Bourgade, Abdelouahed Khalil, Echarki Zerif, Anis Larbi, Katsuiku Hirokawa, Graham Pawelec, Christian Bocti, Guy Lacombe, Gilles Dupuis & Eric H. Frost. (2018) Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer’s Disease?. Frontiers in Aging Neuroscience 10.
Crossref
Chris J. Carter, James France, StJohn Crean & Sim K. Singhrao. (2017) The Porphyromonas gingivalis/Host Interactome Shows Enrichment in GWASdb Genes Related to Alzheimer's Disease, Diabetes and Cardiovascular Diseases. Frontiers in Aging Neuroscience 9.
Crossref
Alice Harding, Ulrike Gonder, Sarita J. Robinson, StJohn Crean & Sim K. Singhrao. (2017) Exploring the Association between Alzheimer’s Disease, Oral Health, Microbial Endocrinology and Nutrition. Frontiers in Aging Neuroscience 9.
Crossref
Anna B. Pritchard, StJohn Crean, Ingar Olsen & Sim K. Singhrao. (2017) Periodontitis, Microbiomes and their Role in Alzheimer’s Disease. Frontiers in Aging Neuroscience 9.
Crossref
Francisco B. Teixeira, Miki T. Saito, Filipe C. Matheus, Rui D. Prediger, Elizabeth S. Yamada, Cristiane S. F. Maia & Rafael R. Lima. (2017) Periodontitis and Alzheimer’s Disease: A Possible Comorbidity between Oral Chronic Inflammatory Condition and Neuroinflammation. Frontiers in Aging Neuroscience 9.
Crossref
Zhuling Guo, Wanyun Lin, Linhan Wu, Kashaf NAZ & Min Yao. (2022) Porphyromonas Gingivalis Trigger the Lipid Metabolism Disorders in Atherosclerosis Via PPARγ-LXRα-ABCA1/ABCG1 Signaling Pathway. SSRN Electronic Journal.
Crossref