Advanced search
Publication Cover
Virulence Volume 6, 2015 - Issue 1
Submit an article Journal homepage
1,325
Views
41
CrossRef citations to date
0
Altmetric
Research Papers

Cryptococcus neoformans induces antimicrobial responses and behaves as a facultative intracellular pathogen in the non mammalian model Galleria mellonella

Nuria Trevijano-ContadorMycology Reference Laboratory; National Center for Microbiology; Instituto de Salud Carlos III; Carretera Majadahonda-Pozuelo, Km2; Majadahonda, 28220, Madrid, Spain
,
Inés Herrero-FernándezMycology Reference Laboratory; National Center for Microbiology; Instituto de Salud Carlos III; Carretera Majadahonda-Pozuelo, Km2; Majadahonda, 28220, Madrid, Spain
,
Irene García-BarbazánMycology Reference Laboratory; National Center for Microbiology; Instituto de Salud Carlos III; Carretera Majadahonda-Pozuelo, Km2; Majadahonda, 28220, Madrid, Spain
,
Liliana ScorzoniMycology Reference Laboratory; National Center for Microbiology; Instituto de Salud Carlos III; Carretera Majadahonda-Pozuelo, Km2; Majadahonda, 28220, Madrid, Spain;Laboratório de Micologia Clínica; Faculdade de Ciências Farmacêuticas; R. Expedicionários do Brasil, 1621, CEP. 14801–902, Araraquara, São Paulo, Brazil
,
Cristina RuedaMycology Reference Laboratory; National Center for Microbiology; Instituto de Salud Carlos III; Carretera Majadahonda-Pozuelo, Km2; Majadahonda, 28220, Madrid, Spain
,
Suélen Andreia RossiMycology Reference Laboratory; National Center for Microbiology; Instituto de Salud Carlos III; Carretera Majadahonda-Pozuelo, Km2; Majadahonda, 28220, Madrid, Spain;Laboratório de Micologia Clínica; Faculdade de Ciências Farmacêuticas; R. Expedicionários do Brasil, 1621, CEP. 14801–902, Araraquara, São Paulo, Brazil
,
Rocío García-RodasMycology Reference Laboratory; National Center for Microbiology; Instituto de Salud Carlos III; Carretera Majadahonda-Pozuelo, Km2; Majadahonda, 28220, Madrid, Spain
&
Oscar ZaragozaMycology Reference Laboratory; National Center for Microbiology; Instituto de Salud Carlos III; Carretera Majadahonda-Pozuelo, Km2; Majadahonda, 28220, Madrid, SpainCorrespondence[email protected]
 show all
Pages 66-74 | Received 25 Aug 2014, Accepted 06 Nov 2014, Published online: 16 Mar 2015

Citations (41)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (5)

Xiuyun Li, Huijun Yang, Ximeng Duan, Min Cui, Wenlan Xing & Shicun Zheng. (2023) Synergistic effect of eravacycline combined with fluconazole against resistant Candida albicans in vitro and in vivo. Expert Review of Anti-infective Therapy 21:11, pages 1259-1267.
Read now
Shoshana Barnoy, Hanan Gancz, Yuewei Zhu, Cary L. Honnold, Daniel V. Zurawski & Malabi M. Venkatesan. (2017) The Galleria mellonella larvae as an in vivo model for evaluation of Shigella virulence. Gut Microbes 8:4, pages 335-350.
Read now
Caroline Maria Marcos, Julhiany de Fátima da Silva, Haroldo Cesar de Oliveira, Patrícia Akemi Assato, Junya de Lacorte Singulani, Angela Maria Lopez, Diana Patricia Tamayo, Orville Hernandez-Ruiz, Juan G McEwen, Maria José Soares Mendes-Giannini & Ana Marisa Fusco-Almeida. (2016) Decreased expression of 14-3-3 in Paracoccidioides brasiliensis confirms its involvement in fungal pathogenesis . Virulence 7:2, pages 72-84.
Read now
Liliana Scorzoni, Ana Carolina Alves de Paula e Silva, Junya de Lacorte Singulani, Fernanda Sangalli Leite, Haroldo Cesar de Oliveira, Rosangela Aparecida Moraes da Silva, Ana Marisa Fusco-Almeida & Maria José Soares Mendes-Giannini. (2015) Comparison of virulence between Paracoccidioides brasiliensis and Paracoccidioides lutzii using Galleria mellonella as a host model. Virulence 6:8, pages 766-776.
Read now
Helene C Eisenman. (2015) Metamorphosis of Galleria mellonella research . Virulence 6:1, pages 1-2.
Read now

Articles from other publishers (36)

Dawid Gniazdo, Wanesa Sasal, Aleksandra Omelaniuk, Weronika Brudz & Wiesław Kaca. (2023) Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity . Advancements of Microbiology 62:3-4, pages 173-182.
Crossref
Nathália Faria Reis, Myrela Conceição Santos de Jesus, Lais Cavalcanti dos Santos Velasco de Souza, Lucas Martins Alcântara, Julia Andrade de Castro Rodrigues, Simone Cristina Pereira Brito, Patrícia de Azambuja Penna, Cecília Stahl Vieira, José Rodrigo Santos Silva, Bruno de Araújo Penna, Ricardo Luiz Dantas Machado, Hector M. Mora-Montes & Andréa Regina de Souza Baptista. (2023) Sporothrix brasiliensis Infection Modulates Antimicrobial Peptides and Stress Management Gene Expression in the Invertebrate Biomodel Galleria mellonella. Journal of Fungi 9:11, pages 1053.
Crossref
Larysa Bugyna, Samuel Kendra & Helena Bujdáková. (2023) Galleria mellonella—A Model for the Study of aPDT—Prospects and Drawbacks. Microorganisms 11:6, pages 1455.
Crossref
Aitor Elizalde-Bielsa, Beatriz Aragón-Aranda, Maite Loperena-Barber, Miriam Salvador-Bescós, Ignacio Moriyón, Amaia Zúñiga-Ripa & Raquel Conde-Álvarez. (2023) Development and evaluation of the Galleria mellonella (greater wax moth) infection model to study Brucella host-pathogen interaction. Microbial Pathogenesis 174, pages 105930.
Crossref
Daniel F. Q. Smith, Quigly Dragotakes, Madhura Kulkarni, J. Marie Hardwick & Arturo Casadevall. (2022) Galleria mellonella immune melanization is fungicidal during infection. Communications Biology 5:1.
Crossref
Gabriela Corrêa Carvalho, Gabriel Davi Marena, Gabriela Ricci Leonardi, Rafael Miguel Sábio, Ione Corrêa, Marlus Chorilli & Tais Maria Bauab. (2022) Lycopene, Mesoporous Silica Nanoparticles and Their Association: A Possible Alternative against Vulvovaginal Candidiasis?. Molecules 27:23, pages 8558.
Crossref
Chenxi Li, Xiaoyu Ma, Lan Ma, Sihui Zhen, Yinan Na, Ping Zhang & Xudong Zhu. (2022) The RNA helicase Ski2 in the fungal pathogen Cryptococcus neoformans highlights key roles in azoles resistance and stress tolerance . Medical Mycology 60:11.
Crossref
Daniel F. Q. Smith, Nathan J. Mudrak, Daniel Zamith-Miranda, Leandro Honorato, Leonardo Nimrichter, Christine Chrissian, Barbara Smith, Gary Gerfen, Ruth E. Stark, Joshua D. Nosanchuk & Arturo Casadevall. (2022) Melanization of Candida auris Is Associated with Alteration of Extracellular pH. Journal of Fungi 8:10, pages 1068.
Crossref
Chenxi Li, Sihui Zhen, Xiaoyu Ma, Lan Ma, Zhen Wang, Ping Zhang & Xudong Zhu. (2022) Involvement of the Noncanonical Polyadenylation Polymerase Cid14 in Fungal Azole Resistance in the Pathogen Cryptococcus neoformans . Pathogens and Disease 80:1.
Crossref
Fabíolla Nacimento do Carmo, Juliana de Camargo Fenley, Maíra Terra Garcia, Rodnei Dennis Rossoni, Juliana Campos Junqueira, Patrícia Pimentel de Barros & Liliana Scorzoni. (2022) Cryptococcus spp. and Cryptococcosis: focusing on the infection in Brazil. Brazilian Journal of Microbiology 53:3, pages 1321-1337.
Crossref
Aaron Curtis, Ulrike Binder & Kevin Kavanagh. (2022) Galleria mellonella Larvae as a Model for Investigating Fungal—Host Interactions. Frontiers in Fungal Biology 3.
Crossref
Kang Ding, Panpan Shen, Zhongwen Xie, Lifang Wang & Xiangli Dang. (2022) In vitro and in vivo antifungal activity of two peptides with the same composition and different distribution. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 252, pages 109243.
Crossref
Kátia Aparecida de Siqueira, Rhavena Graziela Liotti, Janaina Rosa de Sousa, Suzana Junges Vendruscullo, Gilza Barcelos de Souza, Leonardo Gomes de Vasconcelos, Ana Helena Januário, Tiago Antônio de Oliveira Mendes & Marcos Antônio Soares. (2021) Streptomyces griseocarneus R132 expresses antimicrobial genes and produces metabolites that modulate Galleria mellonella immune system. 3 Biotech 11:9.
Crossref
Marcela Q. Granato, Thaís P. Mello, Renata S. Nascimento, Marcos D. Pereira, Thabatta L. S. A. Rosa, Maria C. V. Pessolani, Malachy McCann, Michael Devereux, Marta H. Branquinha, André L. S. Santos & Lucimar F. Kneipp. (2021) Silver(I) and Copper(II) Complexes of 1,10-Phenanthroline-5,6-Dione Against Phialophora verrucosa: A Focus on the Interaction With Human Macrophages and Galleria mellonella Larvae. Frontiers in Microbiology 12.
Crossref
Daniel F. Q. Smith & Arturo Casadevall. (2021) Fungal immunity and pathogenesis in mammals versus the invertebrate model organism Galleria mellonella . Pathogens and Disease 79:3.
Crossref
Chenxi Li, Shaonan Hou, Xiaoyu Ma, Jiajia Li, Liang Huo, Ping Zhang, Xiaoran Hao & Xudong Zhu. (2021) Epigenetic regulation of virulence and the transcription of ribosomal protein genes involves a YEATS family protein in Cryptococcus deneoformans . FEMS Yeast Research 21:1.
Crossref
Winarti Achmad Sarmin Djainal, Khalid Shahin, Matthijs Metselaar, Alexandra Adams & Andrew P. Desbois. (2020) Larva of greater wax moth Galleria mellonella is a suitable alternative host for the fish pathogen Francisella noatunensis subsp. orientalis. BMC Microbiology 20:1.
Crossref
Carolina Firacative, Aziza Khan, Shuyao Duan, Kennio Ferreira-Paim, Diana Leemon & Wieland Meyer. (2020) Rearing and Maintenance of Galleria mellonella and Its Application to Study Fungal Virulence. Journal of Fungi 6:3, pages 130.
Crossref
Sylwia Stączek, Agnieszka Zdybicka-Barabas, Małgorzata Pleszczyńska, Adrian Wiater & Małgorzata Cytryńska. (2020) Aspergillus niger α-1,3-glucan acts as a virulence factor by inhibiting the insect phenoloxidase system. Journal of Invertebrate Pathology 171, pages 107341.
Crossref
Paula I. Seoane & Robin C. May. (2019) Vomocytosis: What we know so far. Cellular Microbiology 22:2.
Crossref
Maria Maryam, Man Shun Fu, Alexandre Alanio, Emma Camacho, Diego S. Goncalves, Eden E. Faneuff, Nina T. Grossman, Arturo Casadevall & Carolina Coelho. (2019) The enigmatic role of fungal annexins: the case of Cryptococcus neoformans. Microbiology 165:8, pages 852-862.
Crossref
Lizeth Lacharme-Lora, Siân V. Owen, Richard Blundell, Rocío Canals, Nicolas Wenner, Blanca Perez-Sepulveda, Wai Yee Fong, Rachel Gilroy, Paul Wigley & Jay C. D. Hinton. (2019) The use of chicken and insect infection models to assess the virulence of African Salmonella Typhimurium ST313. PLOS Neglected Tropical Diseases 13:7, pages e0007540.
Crossref
Nuria Trevijano-Contador & Oscar Zaragoza. (2018) Immune Response of Galleria mellonella against Human Fungal Pathogens. Journal of Fungi 5:1, pages 3.
Crossref
Thais Pereira, Patrícia de Barros, Luciana Fugisaki, Rodnei Rossoni, Felipe Ribeiro, Raquel de Menezes, Juliana Junqueira & Liliana Scorzoni. (2018) Recent Advances in the Use of Galleria mellonella Model to Study Immune Responses against Human Pathogens. Journal of Fungi 4:4, pages 128.
Crossref
Nuria Trevijano-Contador, Haroldo Cesar de Oliveira, Rocío García-Rodas, Suélen Andreia Rossi, Irene Llorente, Ángel Zaballos, Guilhem Janbon, Joaquín Ariño & Óscar Zaragoza. (2018) Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals. PLOS Pathogens 14:5, pages e1007007.
Crossref
Juliana Rizzo, Priscila C. Albuquerque, Julie M. Wolf, Renata Nascimento, Marcos D. Pereira, Joshua D. Nosanchuk & Marcio L. Rodrigues. (2017) Analysis of multiple components involved in the interaction between Cryptococcus neoformans and Acanthamoeba castellanii. Fungal Biology 121:6-7, pages 602-614.
Crossref
Yuto Kochi, Yasuhiko Matsumoto, Kazuhisa Sekimizu & Chikara Kaito. (2017) Two-spotted cricket as an animal infection model of human pathogenic fungi. Drug Discoveries & Therapeutics 11:5, pages 259-266.
Crossref
Ronan Maguire, Suainibhe Kelly & Kevin Kavanagh. 2017. Reference Module in Life Sciences. Reference Module in Life Sciences.
Fernanda Sangalli-Leite, Liliana Scorzoni, Ana Carolina Alves de Paula e Silva, Julhiany de Fátima da Silva, Haroldo Cesar de Oliveira, Junya de Lacorte Singulani, Fernanda Patrícia Gullo, Rosangela Moraes da Silva, Luis Octávio Regasini, Dulce Helena Siqueira da Silva, Vanderlan da Silva Bolzani, Ana Marisa Fusco-Almeida & Maria José Soares Mendes-Giannini. (2016) Synergistic effect of pedalitin and amphotericin B against Cryptococcus neoformans by in vitro and in vivo evaluation. International Journal of Antimicrobial Agents 48:5, pages 504-511.
Crossref
Ana C. Mesa-Arango, Cristina Rueda, Elvira Román, Jessica Quintin, María C. Terrón, Daniel Luque, Mihai G. Netea, Jesus Pla & Oscar Zaragoza. (2016) Cell Wall Changes in Amphotericin B-Resistant Strains from Candida tropicalis and Relationship with the Immune Responses Elicited by the Host. Antimicrobial Agents and Chemotherapy 60:4, pages 2326-2335.
Crossref
Tatiane Benaducci, Janaina de C. O. Sardi, Natalia M. S. Lourencetti, Liliana Scorzoni, Fernanda P. Gullo, Suélen A. Rossi, Jaqueline B. Derissi, Márcia C. de Azevedo Prata, Ana M. Fusco-Almeida & Maria J. S. Mendes-Giannini. (2016) Virulence of Cryptococcus sp. Biofilms In Vitro and In Vivo using Galleria mellonella as an Alternative Model. Frontiers in Microbiology 7.
Crossref
Carlos M. DeLeon-Rodriguez & Arturo Casadevall. (2016) Cryptococcus neoformans: Tripping on Acid in the Phagolysosome. Frontiers in Microbiology 7.
Crossref
Suélen A. Rossi, Nuria Trevijano-Contador, Liliana Scorzoni, Ana Cecilia Mesa-Arango, Haroldo C. de Oliveira, Karin Werther, Tânia de Freitas Raso, Maria J. S. Mendes-Giannini, Oscar Zaragoza & Ana M. Fusco-Almeida. (2016) Impact of Resistance to Fluconazole on Virulence and Morphological Aspects of Cryptococcus neoformans and Cryptococcus gattii Isolates. Frontiers in Microbiology 7.
Crossref
Ulrike Binder, Elisabeth Maurer & Cornelia Lass-Flörl. (2016) Galleria mellonella: An invertebrate model to study pathogenicity in correctly defined fungal species. Fungal Biology 120:2, pages 288-295.
Crossref
Irene García-Barbazán, Nuria Trevijano-Contador, Cristina Rueda, Belén de Andrés, Raquel Pérez-Tavárez, Inés Herrero-Fernández, María Luisa Gaspar & Oscar Zaragoza. (2016) The formation of titan cells in Cryptococcus neoformans depends on the mouse strain and correlates with induction of Th2-type responses . Cellular Microbiology 18:1, pages 111-124.
Crossref
Fausto Almeida, Julie M. Wolf & Arturo Casadevall. (2015) Virulence-Associated Enzymes of Cryptococcus neoformans. Eukaryotic Cell 14:12, pages 1173-1185.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.