558
Views
18
CrossRef citations to date
0
Altmetric
Report

Rapamycin induces pluripotent genes associated with avoidance of replicative senescence

, , , , &
Pages 3841-3851 | Received 10 Oct 2013, Accepted 27 Nov 2013, Published online: 02 Dec 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Mikhail V. Blagosklonny. (2022) Cell senescence, rapamycin and hyperfunction theory of aging. Cell Cycle 21:14, pages 1456-1467.
Read now
Mikhail V. Blagosklonny. (2018) Rapamycin, proliferation and geroconversion to senescence. Cell Cycle 17:24, pages 2655-2665.
Read now
Arpita Baisantry, Sagar Bhayana, Christoph Wrede, Jan Hegermann, Hermann Haller, Anette Melk & Roland Schmitt. (2016) The impact of autophagy on the development of senescence in primary tubular epithelial cells. Cell Cycle 15:21, pages 2973-2979.
Read now
Zhanna V Chitikova, Serguei A Gordeev, Tatiana V Bykova, Svetlana G Zubova, Valery A Pospelov & Tatiana V Pospelova. (2014) Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers. Cell Cycle 13:9, pages 1424-1439.
Read now

Articles from other publishers (14)

Angel Cayo, Whitney Venturini, Danitza Rebolledo-Mira, Rodrigo Moore-Carrasco, Andrés A. Herrada, Estefanía Nova-Lamperti, Claudio Valenzuela & Nelson E. Brown. (2023) Palbociclib-Induced Cellular Senescence Is Modulated by the mTOR Complex 1 and Autophagy. International Journal of Molecular Sciences 24:11, pages 9284.
Crossref
Angel Cayo, Raúl Segovia, Whitney Venturini, Rodrigo Moore-Carrasco, Claudio Valenzuela & Nelson Brown. (2021) mTOR Activity and Autophagy in Senescent Cells, a Complex Partnership. International Journal of Molecular Sciences 22:15, pages 8149.
Crossref
Ding Yao, Yang GangYi & Wu QiNan. (2021) Autophagic dysfunction of β cell dysfunction in type 2 diabetes, a double-edged sword. Genes & Diseases 8:4, pages 438-447.
Crossref
Ekaterina Proshkina, Mikhail Shaposhnikov & Alexey Moskalev. (2020) Genome-Protecting Compounds as Potential Geroprotectors. International Journal of Molecular Sciences 21:12, pages 4484.
Crossref
Mikhail V. Blagosklonny. (2019) Rapamycin for the aging skin. Aging 11:24, pages 12822-12826.
Crossref
Eliane Antonioli, Natália Torres, Mario Ferretti, Carla de Azevedo Piccinato & Andrea Laurato Sertie. (2019) Individual response to mTOR inhibition in delaying replicative senescence of mesenchymal stromal cells. PLOS ONE 14:1, pages e0204784.
Crossref
N. M. Yartseva, T. V. Bykova, S. G. Zubova, V. A. Pospelov & T. V. Pospelova. (2019) Chromosomal Instability and Evolution of Transformed Phenotype in Cell Lines Selected from Senescent Rat Embryonic Fibroblasts with Rapamycin. Cell and Tissue Biology 13:1, pages 18-30.
Crossref
Sören Verstraete, Ilse Vanhorebeek, Esther van Puffelen, Inge Derese, Catherine Ingels, Sascha C. Verbruggen, Pieter J. Wouters, Koen F. Joosten, Jan Hanot, Gonzalo G. Guerra, Dirk Vlasselaers, Jue Lin & Greet Van den Berghe. (2018) Leukocyte telomere length in paediatric critical illness: effect of early parenteral nutrition. Critical Care 22:1.
Crossref
KA. A Rubina, E. V Semina, D. T Diykanov, M. A Boldyreva, P. I Makarevich, Y. V Parfyonova, Zh. A Akopyan & VA. A Tkachuk. (2018) Efficacy of combined use of plasmid constructs containing HGF and angiopoietin-1 genes to restore blood flow in ischemic tissues. Genes & Cells 13:1, pages 56-64.
Crossref
Н. М. Ярцева, Т. В. Быкова, С. Г. Зубова, В. А. Поспелов & Т. В. Поспелова. (2018) ИЗМЕНЕНИЯ КАРИОТИПА И ПРИЗНАКОВ ТРАНСФОРМИРОВАННОГО ФЕНОТИПА КЛЕТОЧНЫХ ЛИНИЙ КРЫСЫ, СЕЛЕКТИРОВАННЫХ С ПОМОЩЬЮ ИНГИБИТОРА mTOR-КИНАЗЫ РАПАМИЦИНА, "Цитология". Tsitologiya:9, pages 712-724.
Crossref
Itziar M.D. Posada, Benoit Lectez, Mukund Sharma, Christina Oetken-Lindholm, Laxman Yetukuri, Yong Zhou, Tero Aittokallio & Daniel Abankwa. (2017) Rapalogs can promote cancer cell stemness in vitro in a Galectin-1 and H-ras-dependent manner . Oncotarget 8:27, pages 44550-44566.
Crossref
Raj Kumar Thapa, Hanh Thuy Nguyen, Jee-Heon Jeong, Jae Ryong Kim, Han-Gon Choi, Chul Soon Yong & Jong Oh Kim. (2017) Progressive slowdown/prevention of cellular senescence by CD9-targeted delivery of rapamycin using lactose-wrapped calcium carbonate nanoparticles. Scientific Reports 7:1.
Crossref
Andrew R. MendelsohnJames W. LarrickJennifer L. Lei. (2017) Rejuvenation by Partial Reprogramming of the Epigenome. Rejuvenation Research 20:2, pages 146-150.
Crossref
Shufeng Chen, Fawn Yeh, Jue Lin, Tet Matsuguchi, Elizabeth Blackburn, Elisa T. Lee, Barbara V. Howard & Jinying Zhao. (2014) Short leukocyte telomere length is associated with obesity in American Indians: The strong heart family study. Aging 6:5, pages 380-389.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.