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α-cell role in β-cell generation and regeneration

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Pages 188-198 | Published online: 01 May 2012

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Shizuka Kaneko. (2021) Novel approaches to pharmacological management of type 2 diabetes in Japan. Expert Opinion on Pharmacotherapy 22:16, pages 2235-2249.
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Scott A. Campbell, Janyne Johnson & Peter E. Light. (2021) Evidence for the existence and potential roles of intra-islet glucagon-like peptide-1. Islets 13:1-2, pages 32-50.
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Carey Sheu & Eustache Paramithiotis. (2017) Towards a personalized assessment of pancreatic function in diabetes. Expert Review of Precision Medicine and Drug Development 2:5, pages 275-285.
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Bernat Soria, Benoit R Gauthier, Franz Martín, Juan R Tejedo, Francisco J Bedoya, Anabel Rojas & Abdelkrim Hmadcha. (2015) Using stem cells to produce insulin. Expert Opinion on Biological Therapy 15:10, pages 1469-1489.
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Shuyuan Chen, Raul A Bastarrachea, Brad J Roberts, V Saroja Voruganti, Patrice A Frost, Edna J Nava-Gonzalez, Hector E Arriaga-Cazares, Jiaxi Chen, Pintong Huang, Ralph A DeFronzo, Anthony G Comuzzie & Paul A Grayburn. (2014) Successful β cells islet regeneration in streptozotocin-induced diabetic baboons using ultrasound-targeted microbubble gene therapy with cyclinD2/CDK4/GLP1. Cell Cycle 13:7, pages 1145-1151.
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Marija Đorđević, Peter Stepper, Clarissa Feuerstein-Akgoz, Clarissa Gerhauser, Verica Paunović, Anja Tolić, Jovana Rajić, Svetlana Dinić, Aleksandra Uskoković, Nevena Grdović, Mirjana Mihailović, Renata Z. Jurkowska, Tomasz P. Jurkowski, Jelena Arambašić Jovanović & Melita Vidaković. (2023) EpiCRISPR targeted methylation of Arx gene initiates transient switch of mouse pancreatic alpha to insulin-producing cells. Frontiers in Endocrinology 14.
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Avinash Kharat, Avinash Sanap & Ramesh Bhonde. 2023. Handbook of Stem Cell Applications. Handbook of Stem Cell Applications 1 20 .
Dipak Sarnobat, Ryan A Lafferty, R Charlotte Moffett, Andrei I Tarasov, Peter R Flatt & Nigel Irwin. (2022) Effects of artemether on pancreatic islet morphology, islet cell turnover and α-cell transdifferentiation in insulin-deficient Glu CreERT2 ; ROSA26-eYFP diabetic mice . Journal of Pharmacy and Pharmacology 74:12, pages 1758-1764.
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Ryan A Lafferty, Laura M McShane, Zara J Franklin, Peter R Flatt, Finbarr P M O’Harte & Nigel Irwin. (2022) Sustained glucagon receptor antagonism in insulin-deficient high-fat-fed mice. Journal of Endocrinology 255:2, pages 91-101.
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Natalie Klempel, Keith Thomas, J. Michael Conlon, Peter R. Flatt & Nigel Irwin. (2022) Alpha-cells and therapy of diabetes: Inhibition, antagonism or death?. Peptides 157, pages 170877.
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Ziqi Cheng, Dongsheng Guo, Aynisahan Ruzi, Tingcai Pan, Kai You, Yan Chen, Xinping Huang, Jiaye Zhang, Fan Yang, Lizhi Niu, Kecheng Xu & Yin-Xiong Li. (2022) Modeling MEN1 with Patient-Origin iPSCs Reveals GLP-1R Mediated Hypersecretion of Insulin. Cells 11:15, pages 2387.
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Jane Rhyu & Run Yu. (2021) Newly discovered endocrine functions of the liver. World Journal of Hepatology 13:11, pages 1611-1628.
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Hyunjin Choi, Marie Shinohara, Masato Ibuki, Masaki Nishikawa & Yasuyuki Sakai. (2021) Differentiation of Human-Induced Pluripotent Stem Cell-Derived Endocrine Progenitors to Islet-like Cells Using a Dialysis Suspension Culture System. Cells 10:8, pages 2017.
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José Bancalero-delosReyes, Alonso Camacho-Ramírez, José Fernández-Vivero, Antonio Ribelles-García, Manuel Macías-Rodríguez, David Almorza-Gomar, Carmen Carrasco-Molinillo, María Ángeles Mayo-Ossorio, José-Arturo Prada-Oliveira & Gonzalo-Martín Perez-Arana. (2021) Glucagon-Producing Cell Expansion in Wistar Rats. Changes to Islet Architecture After Sleeve Gastrectomy. Obesity Surgery 31:5, pages 2241-2249.
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Sandra K Szlapinski, Jamie Bennett, Brenda J Strutt & David J Hill. (2020) Increased alpha and beta cell mass during mouse pregnancy is not dependent on transdifferentiation. Experimental Biology and Medicine 246:5, pages 617-628.
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Ryan A. Lafferty, Neil Tanday, R. Charlotte Moffett, Frank Reimann, Fiona M. Gribble, Peter R. Flatt & Nigel Irwin. (2021) Positive Effects of NPY1 Receptor Activation on Islet Structure Are Driven by Pancreatic Alpha- and Beta-Cell Transdifferentiation in Diabetic Mice. Frontiers in Endocrinology 12.
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Young-Sun Lee, Gyun Jee Song & Hee-Sook Jun. (2021) Betacellulin-Induced α-Cell Proliferation Is Mediated by ErbB3 and ErbB4, and May Contribute to β-Cell Regeneration. Frontiers in Cell and Developmental Biology 8.
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Dana Avrahami, Yue J. Wang, Jonathan Schug, Eseye Feleke, Long Gao, Chengyang Liu, Ali Naji, Benjamin Glaser & Klaus H. Kaestner. (2020) Single-cell transcriptomics of human islet ontogeny defines the molecular basis of β-cell dedifferentiation in T2D. Molecular Metabolism 42, pages 101057.
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Koji Nakashima, Hideaki Kaneto, Masashi Shimoda, Tomohiko Kimura & Kohei Kaku. (2018) Pancreatic alpha cells in diabetic rats express active GLP-1 receptor: Endosomal co-localization of GLP-1/GLP-1R complex functioning through intra-islet paracrine mechanism. Scientific Reports 8:1.
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