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mAbs Volume 6, 2014 - Issue 5
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A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies

Jan StrackeBiochemical and Analytical Research; Large Molecule Research; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany;Pharmaceutical Development & Supplies; Pharma Technical Development Biologics Europe; F. Hoffmann-La Roche Ltd.; Basel, SwitzerlandCorrespondence[email protected]
,
Thomas EmrichLarge Molecule Bioanalytical Research & Development; Pharmaceutical Sciences; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
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Petra RuegerBiochemical and Analytical Research; Large Molecule Research; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
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Tilman SchlothauerBiochemical and Analytical Research; Large Molecule Research; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
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Lothar KlingLarge Molecule Bioanalytical Research & Development; Pharmaceutical Sciences; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
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Alexander KnauppBiochemical and Analytical Research; Large Molecule Research; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
,
Hubert HertenbergerBiochemical and Analytical Research; Large Molecule Research; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
,
Andreas WolfertLarge Molecule Bioanalytical Research & Development; Pharmaceutical Sciences; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
,
Christian SpickBiochemical and Analytical Research; Large Molecule Research; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
,
Wilma LauBiochemical and Analytical Research; Large Molecule Research; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
,
Georg DrabnerBiochemical and Analytical Research; Large Molecule Research; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
,
Ulrike ReiffBiochemical and Analytical Research; Large Molecule Research; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
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Hans KollBiochemical and Analytical Research; Large Molecule Research; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
&
Apollon PapadimitriouLarge Molecule Bioanalytical Research & Development; Pharmaceutical Sciences; Roche Pharma Research and Early Development (pRED); Roche Innovation Center; Penzberg, Germany
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Pages 1229-1242 | Received 07 May 2014, Accepted 16 Jun 2014, Published online: 30 Oct 2014

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