757
Views
37
CrossRef citations to date
0
Altmetric
Commentary & View

Prion proteostasis

Hsp104 meets its supporting cast

&
Pages 135-140 | Received 08 Dec 2008, Accepted 22 Jan 2009, Published online: 25 Nov 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Meredith E Jackrel & James Shorter. (2015) Engineering enhanced protein disaggregases for neurodegenerative disease. Prion 9:2, pages 90-109.
Read now
Meredith E Jackrel & James Shorter. (2014) Reversing deleterious protein aggregation with re-engineered protein disaggregases. Cell Cycle 13:9, pages 1379-1383.
Read now
Mariana P Torrente & James Shorter. (2013) The metazoan protein disaggregase and amyloid depolymerase system. Prion 7:6, pages 457-463.
Read now
Jennifer E Dulle & Heather L True. (2013) Low activity of select Hsp104 mutants is sufficient to propagate unstable prion variants. Prion 7:5, pages 394-403.
Read now
Daniel W. Summers, Peter M. Douglas & Douglas M. Cyr. (2009) Prion propagation by Hsp40 molecular chaperones. Prion 3:2, pages 59-64.
Read now

Articles from other publishers (31)

Macy L. Sprunger & Meredith E. Jackrel. (2021) Prion-Like Proteins in Phase Separation and Their Link to Disease. Biomolecules 11:7, pages 1014.
Crossref
Yiwen R. Chen, Inbal Ziv, Kavya Swaminathan, Joshua E. Elias & Daniel F. Jarosz. (2021) Protein aggregation and the evolution of stress resistance in clinical yeast. Philosophical Transactions of the Royal Society B: Biological Sciences 376:1826, pages 20200127.
Crossref
Yoshiyuki Suzuki. (2021) Chaperone therapy for molecular pathology in lysosomal diseases. Brain and Development 43:1, pages 45-54.
Crossref
Melanie Y. Pullen, Conrad C. Weihl & Heather L. True. (2020) Client processing is altered by novel myopathy-causing mutations in the HSP40 J domain. PLOS ONE 15:6, pages e0234207.
Crossref
Zachary M. March, Korrie L. Mack & James Shorter. (2019) AAA+ Protein-Based Technologies to Counter Neurodegenerative Disease. Biophysical Journal 116:8, pages 1380-1385.
Crossref
Amber Tariq, JiaBei Lin, Megan M Noll, Mariana P Torrente, Korrie L Mack, Oscar Hernandez Murillo, Meredith E Jackrel & James Shorter. (2018) Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain. FEMS Yeast Research 18:5.
Crossref
Alice Ford HarrisonJames Shorter. (2017) RNA-binding proteins with prion-like domains in health and disease. Biochemical Journal 474:8, pages 1417-1438.
Crossref
Meredith E. Jackrel & James Shorter. (2017) Protein-Remodeling Factors As Potential Therapeutics for Neurodegenerative Disease. Frontiers in Neuroscience 11.
Crossref
Zachary M. March, Oliver D. King & James Shorter. (2016) Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease. Brain Research 1647, pages 9-18.
Crossref
Mariana P. Torrente, Edward Chuang, Megan M. Noll, Meredith E. Jackrel, Michelle S. Go & James Shorter. (2016) Mechanistic Insights into Hsp104 Potentiation. Journal of Biological Chemistry 291:10, pages 5101-5115.
Crossref
Max J. Dörfel & Gholson J. Lyon. (2015) The biological functions of Naa10 — From amino-terminal acetylation to human disease. Gene 567:2, pages 103-131.
Crossref
Laura M. Castellano, Stephen M. Bart, Veronica M. Holmes, Drew Weissman & James Shorter. (2015) Repurposing Hsp104 to Antagonize Seminal Amyloid and Counter HIV Infection. Chemistry & Biology 22:8, pages 1074-1086.
Crossref
Jennifer E. Dulle, Kevin C. Stein & Heather L. True. (2014) Regulation of the Hsp104 Middle Domain Activity Is Critical for Yeast Prion Propagation. PLoS ONE 9:1, pages e87521.
Crossref
Fabrice Caudron & Yves Barral. (2013) A Super-Assembly of Whi3 Encodes Memory of Deceptive Encounters by Single Cells during Yeast Courtship. Cell 155:6, pages 1244-1257.
Crossref
Keita Oishi, Hiroshi Kurahashi, Chan‐Gi Pack, Yasushi Sako & Yoshikazu Nakamura. (2013) A bipolar functionality of Q/N‐rich proteins: Lsm4 amyloid causes clearance of yeast prions. MicrobiologyOpen 2:3, pages 415-430.
Crossref
Ulrike K. Resenberger, Veronika Müller, Lisa M. Munter, Michael Baier, Gerd Multhaup, Mark R. Wilson, Konstanze F. Winklhofer & Jörg Tatzelt. (2012) The Heat Shock Response Is Modulated by and Interferes with Toxic Effects of Scrapie Prion Protein and Amyloid β. Journal of Biological Chemistry 287:52, pages 43765-43776.
Crossref
Morgan E. DeSantis & James Shorter. (2012) Hsp104 Drives “Protein-Only” Positive Selection of Sup35 Prion Strains Encoding Strong [PSI]. Chemistry & Biology 19:11, pages 1400-1410.
Crossref
Martin L. Duennwald, AnaLisa Echeverria & James Shorter. (2012) Small Heat Shock Proteins Potentiate Amyloid Dissolution by Protein Disaggregases from Yeast and Humans. PLoS Biology 10:6, pages e1001346.
Crossref
Oliver D. King, Aaron D. Gitler & James Shorter. (2012) The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease. Brain Research 1462, pages 61-80.
Crossref
Eugene V Koonin. (2012) Does the central dogma still stand?. Biology Direct 7:1, pages 27.
Crossref
Morgan E. DeSantis & James Shorter. (2012) The elusive middle domain of Hsp104 and ClpB: Location and function. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:1, pages 29-39.
Crossref
James Shorter. (2011) The Mammalian Disaggregase Machinery: Hsp110 Synergizes with Hsp70 and Hsp40 to Catalyze Protein Disaggregation and Reactivation in a Cell-Free System. PLoS ONE 6:10, pages e26319.
Crossref
Daniel C. Masison. 2011. Protein Chaperones and Protection from Neurodegenerative Diseases. Protein Chaperones and Protection from Neurodegenerative Diseases 277 314 .
James Shorter. 2011. Protein Chaperones and Protection from Neurodegenerative Diseases. Protein Chaperones and Protection from Neurodegenerative Diseases 235 259 .
Robert T. SauerTania A. Baker. (2011) AAA+ Proteases: ATP-Fueled Machines of Protein Destruction. Annual Review of Biochemistry 80:1, pages 587-612.
Crossref
Theodora C. Sideri, Klement Stojanovski, Mick F. Tuite & Chris M. Grant. (2010) Ribosome-associated peroxiredoxins suppress oxidative stress–induced de novo formation of the [ PSI + ] prion in yeast . Proceedings of the National Academy of Sciences 107:14, pages 6394-6399.
Crossref
Randal Halfmann, Simon Alberti & Susan Lindquist. (2010) Prions, protein homeostasis, and phenotypic diversity. Trends in Cell Biology 20:3, pages 125-133.
Crossref
Valerie Grimminger-Marquardt & Hilal A. Lashuel. (2010) Structure and function of the molecular chaperone Hsp104 from yeast. Biopolymers 93:3, pages 252-276.
Crossref
Shilpa Vashist, Mimi Cushman & James Shorter. (2010) Applying Hsp104 to protein-misfolding disordersThis paper is one of a selection of papers published in this special issue entitled 8th International Conference on AAA Proteins and has undergone the Journal's usual peer review process.. Biochemistry and Cell Biology 88:1, pages 1-13.
Crossref
James Shorter. (2010) Emergence and natural selection of drug-resistant prions. Molecular BioSystems 6:7, pages 1115.
Crossref
Jessica C.S. Brown & Susan Lindquist. (2009) A heritable switch in carbon source utilization driven by an unusual yeast prion. Genes & Development 23:19, pages 2320-2332.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.