Assessment of phytochemicals, antioxidant properties, and in vivo antidiarrheal activity of date palm (Phoenix dactylifera L.)

References

• Sinan, K. I.; Chiavaroli, A.; Orlando, G.; Bene, K.; Zengin, G.; Cziáky, Z.; Jekő, J.; Fawzi Mahomoodally, M.; Picot-Allain, M. C. N.; Menghini, L. Biopotential of Bersamaabyssinicafresen Stem Bark Extracts: UHPLC Profiles, Antioxidant, Enzyme Inhibitory, and Antiproliferative Propensities. Antioxidants. 2020, 9(2), 163. DOI: 10.3390/antiox9020163.
   Web of Science ®Google Scholar
• Anza, M.; Worku, F.; Libsu, S.; Mamo, F.; Endale, M. Phytochemical Screening and Antibacterial Activity of Leaves Extract of Bersamaabyssinica. J. Adv. Bot. Zool. 2015, 3(2), 1–5.
   Google Scholar
• Sinan, K. I.; Bene, K.; Zengin, G.; Diuzheva, A.; Jekő, J.; Cziáky, Z.; Picot-Allain, C. M. N.; Mollica, A.; Rengasamy, K. R.; Mahomoodally, M. F. A Comparative Study of the HPLC-MS Profiles and Biological Efficiency of Different Solvent Leaf Extracts of Two African Plants: Bersama Abyssinica and Scoparia Dulcis. Int. J. Env. Heal. Res. 2019, 31(3), 285–297. DOI: 10.1080/09603123.2019.1652885.
   PubMed Web of Science ®Google Scholar
• Ekiert, H. M.; Szopa, A. Biological Activities of Natural Products. Molecules. 2020, 25(23), 5769. DOI: 10.3390/molecules25235769.
   PubMed Web of Science ®Google Scholar
• Agunu, A.; y, S.; Gabriel, O. A.; Zezi, A. U.; Abdurrahman, E. M. Evaluation of Five Nigerian Medicinal Plants Used in Treatment of Diarrhea in Nigeria. J. Ethnopharmacol. 2005, 61, 209–213.
   Google Scholar
• Al-Farsi, M.; Lee, C. Y. Optimization of Phenolics and Dietary Fiber Extraction from Date Seeds. Food Chem. 2008, 108(3), 977–985. DOI: 10.1016/j.foodchem.2007.12.009.
   PubMed Web of Science ®Google Scholar
• FAO. (2020). FAOSTAT Statistical Database. Livestock Primary. http://www.fao. org/faostat/en/#data/QL. (Accessed Aug 26, 2021).
   Google Scholar
• Besbes, S.; Blecker, C.; Deroanne, C.; Drira, N.; Attia, H. Date Seeds: Chemical Composition and Characteristic Profiles of the Lipid Fraction. J. Food Chem. 2004, 84(4), 577–584. DOI: 10.1016/S0308-8146(03)00281-4.
   Web of Science ®Google Scholar
• Djaoud, K.; Boulekbache‐Makhlouf, L.; Yahia, M.; Mansouri, H.; Mansouri, N.; Madani, K.; Romero, A. Dairy Dessert Processing: Effect of Sugar Substitution by Date Syrup and Powder on Its Quality Characteristics. J. Food Pro. Pres. 2020, 44(5), 14414. DOI: 10.1111/jfpp.14414.
   Web of Science ®Google Scholar
• Halabi, A. A.; Elwakil, B. H.; Hagar, M.; Olama, Z. A. Date Fruit (Phoenix Dactylifera L.) Cultivar Extracts: Nanoparticle Synthesis, Antimicrobial and Antioxidant Activities. Molecules. 2022, 27(16), 5165. DOI: 10.3390/molecules27165165.
   PubMed Web of Science ®Google Scholar
• Manickvasagan, A.; Kumar, C.; Al-Attabi, Z. Effect of Sugar Replacement with Date Paste and Date Syrup on Texture and Sensory Quality of Kesari (Traditional Indian Dessert). J Agri. Mar. Sci. 2018, 22(1), 67. DOI: 10.24200/jams.vol22iss1pp67-74.
   Google Scholar
• Al-Khayri, J.; Naik, P. Date Palm Micropropagation: Advances and Applications. Ciênc. Agrotec. 2017, 41(4), 347–358. DOI: 10.1590/1413-70542017414000217.
   Web of Science ®Google Scholar
• Lim, Y.; Murtijaya, J. Antioxidant Properties of Phyllanthusamarus Extracts as Affected by Different Drying Methods. LWT - Food Sci. Tech. 2007, 40(9), 1664–1669. DOI: 10.1016/j.lwt.2006.12.013.
   Web of Science ®Google Scholar
• Park, Y.; Jung, S.; Kang, S.; Heo, B.; Arancibia-Avila, P.; Toledo, F.; Drzewiecki, J.; Namiesnik, J.; Gorinstein, S. Antioxidants and Proteins in Ethylene-Treated Kiwifruits. Food Chem. 2008, 107(2), 640–648. DOI: 10.1016/j.foodchem.2007.08.070.
   Web of Science ®Google Scholar
• Brand-Williams, W.; Cuvelier, M.; Berset, C. Use of a Free Radical Method to Evaluate Antioxidant Activity. LWT - Food Sci. Tech. 1995, 28(1), 25–30. DOI: 10.1016/S0023-6438(95)80008-5.
   Web of Science ®Google Scholar
• Qadir, R.; Anwar, F.; Naseem, K.; Tahir, M. H.; Alhumade, H. Enzyme-Assisted Extraction of Phenolics from Capparis Spinosa Fruit: Modeling and Optimization of the Process by RSM and ANN. ACS Omega. 2022, 7(37), 33031–33038. DOI: 10.1021/acsomega.2c02850.
   PubMed Web of Science ®Google Scholar
• Kamgang, R.; Youmbi Mboumi, R.; FoyetFondjo, A.; FokamTagne, M.; Mengue N’dillé, G.; NgogangYonkeu, J. Antihyperglycaemic Potential of the Water–Ethanol Extract of Kalanchoecrenata (Crassulaceae). J. Nat. Med. 2008, 62(1), 34–40. DOI: 10.1007/s11418-007-0179-y.
   PubMed Web of Science ®Google Scholar
• FokamTagne, M.; Noubissi, P.; Fankem, G.; Kamgang, R. Effects of Oxalis Barrelieri L. (Oxalidaceae) Aqueous Extract on Diarrhea Induced by Shigelladysenteriae Type 1 in Rats. Heal. Sci. Rep. 2017, 1(2), e20. DOI: 10.1002/hsr2.20.
   PubMedGoogle Scholar
• Ezekwesili, C. N.; Obiora, K. A.; Ugwu, O. P. Evaluation of Anti-Diarrhoeal Property of Crude Aqueous Extract of Ocimumgratissimum L. (Labiatae) in Rats. Biokemistr. 2004, 16(2), 122–131. DOI: 10.4314/biokem.v16i2.32580.
   Google Scholar
• FokamTagne, M.; Akaou, H.; Noubissi, P.; FoyetFondjo, A.; Rékabi, Y.; Wambe, H.; Kamgang, R.; Essame Oyono, J.-L. Effect of the Hydroethanolic Extract of Bixaorellana Linn (Bixaceae) Leaves on Castor Oil-Induced Diarrhea in Swiss Albino Mice. Gastroent. Res. Pract. 2019, 2019, 1–8. DOI: 10.1155/2019/6963548.
   Web of Science ®Google Scholar
• Saleh, E.; Tawfik, M.; Abu-Tarboush, H. Phenolic Contents and Antioxidant Activity of Various Date Palm (Phoenixdactylifera L.) Fruits from Saudi Arabia. Food Nut. Sci. 2011, 02(10), 1134–1141. DOI: 10.4236/fns.2011.210152.
   Google Scholar
• Afifi, F.; Kasabri, V.; Al-Jaber, H.; Abu-Irmaileh, B.; Al-Qudah, M.; Abaza, I. Composition and Biological Activity of Volatile Oil from Salvia Judaica and S. Multicaulis from Jordan. Nat. Prod. Comm. 2016, 11(4), 1934578X1601100. DOI: 10.1177/1934578X1601100429.
   Web of Science ®Google Scholar
• Abou-Elella, F.; Mourad, R. Anticancer and Anti-Oxidant Potentials of Ethanolic Extracts of Phoenix Dactylifera, Musa Acuminata and Cucurbita Maxima. Res. J. Pharm. Bio. Chem. Sci. 2015, 6(1), 710–720.
   Web of Science ®Google Scholar
• Al-Jasass, F.; Siddiq, M.; Sogi, D. Antioxidants Activity and Color Evaluation of Date Fruit of Selected Cultivars Commercially Available in the United States. Adv. Chem. 2015, 2015, 1–5. DOI: 10.1155/2015/567203.
   Google Scholar
• Lu, Y.; Yeap Foo, L. Antioxidant and Radical Scavenging Activities of Polyphenols from Apple Pomace. Food Chem. 2000, 68(1), 81–85. DOI: 10.1016/S0308-8146(99)00167-3.
   Web of Science ®Google Scholar
• Bano, Y.; Rakha, A.; Issa Khan, M.; Asgher, M. Chemical Composition and Antioxidant Activity of Date (Phoenix Dactylifera L.) Varieties at Various Maturity Stages. Food Sci. Technol. Campinas. 2022, 42, e29022. DOI: 10.1590/fst.29022.
   Google Scholar
• Eid, N.; Enani, S.; Walton, G.; Corona, G.; Costabile, A.; Gibson, G.; Rowland, I.; Spencer, J. P. E. The Impact of Date Palm Fruits and Their Component Polyphenols, on Gut Microbial Ecology, Bacterial Metabolites and Colon Cancer Cell Proliferation. J. Nut. Sci. 2014, 3, e46. DOI: 10.1017/jns.2014.16.
   PubMedGoogle Scholar
• Hamad, I.; AbdElgawad, H.; Al Jaouni, S.; Zinta, G.; Asard, H.; Hassan, S.; Hegab, M.; Hagagy, N.; Selim, S. Metabolic Analysis of Various Date Palm Fruit (Phoenix Dactylifera L.) Cultivars from Saudi Arabia to Assess Their Nutritional Quality. Molecules. 2015, 20(8), 13620–13641. DOI: 10.3390/molecules200813620.
   PubMed Web of Science ®Google Scholar
• Bouhlali, E.; Alem, C.; Ennassir, J.; Benlyas, M.; Mbark, A.; Zegzouti, Y. Phytochemical Compositions and Antioxidant Capacity of Three Date (Phoenix Dactylifera L.) Seeds Varieties Grown in the South East Morocco. J. Saudi Soc. Agri. Sci. 2017, 16(4), 350–357. DOI: 10.1016/j.jssas.2015.11.002.
   Google Scholar
• Cheyma, B.; Zineb, G.; Mokhtar, S. Effects of Extraction Solvents on Bound Phenolic Contents and Antioxidant Activities of Tantboucht Dates (Phoenix Dactylifera L.) from Algeria. J. Chem. Pharmaceutical Res. 2015, 7(7), 27–31.
   Google Scholar
• Hussain, M.; Farooq, M.; Syed, Q. Nutritional and Biological Characteristics of the Date Palm Fruit (Phoenix Dactylifera L.) – a Review. Food Biosci. 2020, 34, 100509. DOI: 10.1016/j.fbio.2019.100509.
   Web of Science ®Google Scholar
• Akuodor, G.; Muazzam, I.; Usman-Idris, M.; Megwas, U.; Akpan, J.; Chilaka, K.; Okoroafor, U.; Osunkwo, U. Evaluation of the Antidiarrheal Activity of Methanol Leaf Extract of Bombaxbuonopozense in Rats. Ibnosina J. Med. Biomedical Sci. 2011, 3(1), 15–20. DOI: 10.4103/1947-489X.210845.
   Google Scholar
• Al-Juhaimi, F.; Ghafoor, K.; Özcan, M. M.; Jahurul, M. H. A.; Babiker, E. E.; Jinap, S.; Sahena, F.; Sharifudin, M. S.; Zaidul, I. S. M. Effect of Various Food Processing and Handling Methods on Preservation of Natural Antioxidants in Fruits and Vegetables. J. Food Sci. Technol. 2018, 55(10), 3872–3880. DOI: 10.1007/s13197-018-3370-0.
   PubMed Web of Science ®Google Scholar
• Tagne, M. A.; Kamgang, R.; Noubissi, P. A.; Oyono, J. L. Activity of Oxalis Barrelieri Aqueous Extract on Rat Secretory Diarrhea and Intestine Transit. J. App. Pharm. Sci. 2015, 5(1), 058–62.
   Google Scholar
• Kuras, E. R.; Warren, P. S.; Zinda, J. A.; Aronson, M. F.; Cilliers, S.; Goddard, M. A.; Nilon, C. H.; Winkler, R. Urban Socioeconomic Inequality and Biodiversity Often Converge, but Not Always: A Global Meta-Analysis. Lands. Urb. Plan. 2020, 198, 103799. DOI: 10.1016/j.landurbplan.2020.103799.
   Web of Science ®Google Scholar
• Ibrahim, S. A.; Fidan, H.; Aljaloud, S. O.; Stankov, S.; Ivanov, G. Application of Date (Phoenix Dactylifera L.) Fruit in the Composition of a Novel Snack Bar. Foods. 2021, 10(5), 918. DOI: 10.3390/foods10050918.
   PubMed Web of Science ®Google Scholar
• Bakare, R. I.; Magbagbeola, O. A.; Akinwande, A. I.; Okunowo, O. W.; Green, M. Antidiarrhoeal Activity of Aqueous Leaf Extract of Momordicacharantia in Rats. J Pharma. Phyt. 2011, 3(1), 1–7. DOI:10.5897/JPP.9000010.
   Google Scholar
• Veiga, V. F.; Zunino, L.; Calixto, J. B.; Patitucci, M. L.; Pinto, A. C. Phytochemical and Antioedematogenic Studies of Commercial Copaíba Oils Available in Brazil. Phytother. Res. 2001, 15(6), 476–480. DOI: 10.1002/ptr.976.
   PubMed Web of Science ®Google Scholar
• Emudainohwo, J.; Erhirhie, E.; Moke, E. Anti-Diarrheal Activity of the Aqueous Leaf Extract of Ageratum Conyzoides in Wistar Rats. J Appl. Sci. Environ. Man. 2015, 19(2), 169–175. DOI: 10.4314/jasem.v19i2.1.
   Google Scholar
• Derebe, D.; Abdulwuhab, M.; Wubetu, M.; Mohammed, F. Investigation of the Antidiarrheal and Antimicrobial Activities of 80% Methanolic Leaf Extract of Discopodiumpenninervum (Hochst.). Evid. Based Compl. Alter. Med. 2018, 2018, 1360486. DOI: 10.1155/2018/1360486.
   PubMed Web of Science ®Google Scholar
• Ghafoor, K.; Sarker, M. Z. I.; Al-Juhaimi, F. Y.; Babiker, E. E.; Alkaltham, M. S.; Almubarak, A. K.; Ahmed, I. A. M. Innovative and Green Extraction Techniques for the Optimal Recovery of Phytochemicals from Saudi Date Fruit Flesh. Processes. 2022, 10(11), 2224. DOI: 10.3390/pr10112224.
   Web of Science ®Google Scholar
• Gakunga, J. N.; Mirianga, B.; Muwonge, H.; Sembajwe, L. F.; Kateregga, J. Antidiarrheal Activity of Ethanolic Fruit Extract of Psidiumguajava (Guava) in Castor Oil Induced Diarrhea in Albino Rats. Nat. J. Phys. Pharm. Pharmac. 1970, 3(2), 191–197. DOI: 10.5455/njppp.2013.3.100620131.
   Google Scholar
• Ganitkevich, V.; Hasse, V.; Pfitzer, G. Ca2þ-Dependent and Ca2þ-Independent Regulation of Smooth Muscle Contraction. J. Mus. Res. Cell Motil. 2002, 23(1), 47–52. DOI: 10.1023/A:1019956529549.
   PubMed Web of Science ®Google Scholar
• Adeniyi, O. S.; Omale, J.; Omeje, S. C.; Edino, V. O. Antidiarrheal Activity of Hexane Extract of Citrus limon Peel in an Experimental Animal Model. J. Integ. Med. 2017, 15(2), 158–164. DOI: 10.1016/S2095-4964(17)60327-3.
   PubMedGoogle Scholar