Biologics: Targets and Therapy, Volume 12, Issue (2018)

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Biologics: Targets and Therapy, Volume 12, Issue (2018)

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Review

Review Article
Tuberculosis and viral hepatitis infection in Eastern Europe, Asia, and Latin America: impact of tumor necrosis factor-α inhibitors in clinical practice
Yi-Hsing Chen, Hellen MDS de Carvalho, Umut Kalyoncu, Lyndon John Q Llamado, Gaston Solano, Ron Pedersen, Galina Lukina, Juan J Lichauco & Radu S Vasilescu
Pages: 1-9
Published online: 07 Dec 2022
AbstractforTuberculosis and viral hepatitis infection in Eastern Europe, Asia, and Latin America: impact of tumor necrosis factor-α inhibitors in clinical practice | Full Text | References | PDF (297.8 KB)
  • 83 Views
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Open Access
Review Article
Bezlotoxumab: an emerging monoclonal antibody therapy for prevention of recurrent Clostridium difficile infection
Bhagyashri D Navalkele & Teena Chopra
Pages: 11-21
Published online: 18 Jan 2018
AbstractforBezlotoxumab: an emerging monoclonal antibody therapy for prevention of recurrent Clostridium difficile infection | Full Text | References | PDF (190.4 KB)
  • 284 Views
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Open Access

Original Research

Article
Analytical characterization of recombinant hCG and comparative studies with reference product
Rajamannar Thennati, Sanjay Kumar Singh, Nitin Nage, Yena Patel, Sandip Kumar Bose, Vinod Burade & Ranjit Sudhakar Ranbhor
Pages: 23-35
Published online: 30 Jan 2018
AbstractforAnalytical characterization of recombinant hCG and comparative studies with reference product | Full Text | References | PDF (5 MB)
  • 262 Views
  • 7 CrossRef citations
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Open Access
Article
Correlation between HLA haplotypes and the development of antidrug antibodies in a cohort of patients with rheumatic diseases
Maurizio Benucci, Arianna Damiani, Francesca Li Gobbi, Francesca Bandinelli, Maria Infantino, Valentina Grossi, Mariangela Manfredi, Guillaume Noguier & Francesca Meacci
Pages: 37-41
Published online: 07 Dec 2022
AbstractforCorrelation between HLA haplotypes and the development of antidrug antibodies in a cohort of patients with rheumatic diseases | Full Text | References | PDF (169.9 KB)
  • 103 Views
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Open Access

Review

Review Article
New frontiers in oncolytic viruses: optimizing and selecting for virus strains with improved efficacy
Kenneth Lundstrom
Pages: 43-60
Published online: 07 Dec 2022
AbstractforNew frontiers in oncolytic viruses: optimizing and selecting for virus strains with improved efficacy | Full Text | References | PDF (238.4 KB)
  • 233 Views
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Open Access

Original Research

Article
The conundrum of indeterminate QuantiFERON-TB Gold results before anti-tumor necrosis factor initiation
Shahrad Hakimian, Yevgeniy Popov, Abbas H Rupawala, Karen Salomon-Escoto, Steven Hatch & Randall Pellish
Pages: 61-67
Published online: 27 Feb 2018
AbstractforThe conundrum of indeterminate QuantiFERON-TB Gold results before anti-tumor necrosis factor initiation | Full Text | References | PDF (438.7 KB)
  • 124 Views
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Open Access

Case Report

Case Report
Efficacy of ustekinumab against infliximab-induced psoriasis and arthritis associated with Crohn’s disease
Satohiro Matsumoto & Hirosato Mashima
Pages: 69-73
Published online: 19 Jul 2018
AbstractforEfficacy of ustekinumab against infliximab-induced psoriasis and arthritis associated with Crohn’s disease | Full Text | References | PDF (4.4 MB)
  • 123 Views
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Open Access

Original Research

Article
Combined treatment with metformin and gefitinib overcomes primary resistance to EGFR-TKIs with EGFR mutation via targeting IGF-1R signaling pathway
Yong-hong Pan, Lin Jiao, Cai-yu Lin, Cong-hua Lu, Li Li, Heng-yi Chen, Yu-bo Wang & Yong He
Pages: 75-86
Published online: 20 Aug 2018
AbstractforCombined treatment with metformin and gefitinib overcomes primary resistance to EGFR-TKIs with EGFR mutation via targeting IGF-1R signaling pathway | Full Text | References | PDF (2.7 MB)
  • 108 Views
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Open Access

Review

Review Article
Focus on biosimilar etanercept – bioequivalence and interchangeability
Fabrizio Cantini & Maurizio Benucci
Pages: 87-95
Published online: 07 Dec 2022
AbstractforFocus on biosimilar etanercept – bioequivalence and interchangeability | Full Text | References | PDF (175.3 KB)
  • 142 Views
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Open Access

Original Research

Article
A descriptive analysis of real-world treatment patterns of innovator (Remicade®) and biosimilar infliximab in an infliximab-naïve Turkish population
Yusuf Yazici, Lin Xie, Adesuwa Ogbomo, Lorie A Ellis, Kavitha Goyal, Amanda Teeple, Ece A Mutlu & Ismail Simsek
Pages: 97-106
Published online: 02 Oct 2018
AbstractforA descriptive analysis of real-world treatment patterns of innovator (Remicade®) and biosimilar infliximab in an infliximab-naïve Turkish population | Full Text | References | PDF (580.4 KB)
  • 77 Views
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Open Access
Article
Designing of CD8+ and CD8+-overlapped CD4+ epitope vaccine by targeting late and early proteins of human papillomavirus
Satyavani Kaliamurthi, Gurudeeban Selvaraj, Aman Chandra Kaushik, Ke-Ren Gu & Dong-Qing Wei
Pages: 107-125
Published online: 07 Dec 2022
AbstractforDesigning of CD8+ and CD8+-overlapped CD4+ epitope vaccine by targeting late and early proteins of human papillomavirus | Full Text | References | PDF (3.2 MB)
  • 169 Views
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Open Access
Article
Analysis of real-world treatment patterns in a matched rheumatology population that continued innovator infliximab therapy or switched to biosimilar infliximab
Yusuf Yazici, Lin Xie, Adesuwa Ogbomo, Lorie A Ellis, Kavitha Goyal, Amanda Teeple & Ismail Simsek
Pages: 127-134
Published online: 07 Dec 2022
AbstractforAnalysis of real-world treatment patterns in a matched rheumatology population that continued innovator infliximab therapy or switched to biosimilar infliximab | Full Text | References | PDF (504.3 KB)
  • 77 Views
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Open Access

Review

Review Article
Two decades with omalizumab: what we still have to learn
Cristoforo Incorvaia, Marina Mauro, Elena Makri, Gualtiero Leo & Erminia Ridolo
Pages: 135-142
Published online: 07 Dec 2022
AbstractforTwo decades with omalizumab: what we still have to learn | Full Text | References | PDF (175.6 KB)
  • 110 Views
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Open Access

Original Research

Article
The effects of golimumab treatment on systolic and diastolic left ventricular function in ankylosing spondylitis
SC Heslinga, TC Konings, IE van der Horst-Bruinsma, O Kamp, VP van Halm, HACM de Bruin-Bon, MJ Peters & MT Nurmohamed
Pages: 143-149
Published online: 07 Dec 2022
AbstractforThe effects of golimumab treatment on systolic and diastolic left ventricular function in ankylosing spondylitis | Full Text | References | PDF (458 KB)
  • 69 Views
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Open Access
Article
Analysis of drug utilization and health care resource consumption in patients with psoriasis and psoriatic arthritis before and after treatment with biological therapies
Luca Degli Esposti, Valentina Perrone, Diego Sangiorgi, Stefano Buda, Margherita Andretta, Maurizio Rossini & Giampiero Girolomoni
Pages: 151-158
Published online: 12 Nov 2018
AbstractforAnalysis of drug utilization and health care resource consumption in patients with psoriasis and psoriatic arthritis before and after treatment with biological therapies | Full Text | References | PDF (633.3 KB)
  • 118 Views
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Open Access
Article
Structural and functional comparability study of anti-CD20 monoclonal antibody with reference product
Sanjay Kumar Singh, Santosh Pokalwar, Sandip Bose, Shivika Gupta, Suhani Almal & Ranjit Sudhakar Ranbhor
Pages: 159-170
Published online: 07 Dec 2022
AbstractforStructural and functional comparability study of anti-CD20 monoclonal antibody with reference product | Full Text | References | PDF (2.8 MB)
  • 130 Views
  • 5 CrossRef citations
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Open Access
Article
Infliximab dose adjustment can improve the clinical and radiographic outcomes of rheumatoid arthritis patients: REVIVE study results
Yuji Nozaki, Yasuaki Nagare, Chisato Ashida, Daisuke Tomita, Akinori Okada, Asuka Inoue, Koji Kinoshita, Masanori Funauchi & Itaru Matsumura
Pages: 171-182
Published online: 07 Dec 2022
AbstractforInfliximab dose adjustment can improve the clinical and radiographic outcomes of rheumatoid arthritis patients: REVIVE study results | Full Text | References | PDF (906 KB)
  • 65 Views
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Open Access

Perspectives

Article
Combination of EGFR-TKIs with chemotherapy versus chemotherapy or EGFR-TKIs alone in advanced NSCLC patients with EGFR mutation
Miaomiao Wen, Jinghua Xia, Ying Sun, Xuejiao Wang, Xianghui Fu, Yanning Zhang, Zhipei Zhang, Yongan Zhou & Xiaofei Li
Pages: 183-190
Published online: 07 Dec 2022
AbstractforCombination of EGFR-TKIs with chemotherapy versus chemotherapy or EGFR-TKIs alone in advanced NSCLC patients with EGFR mutation | Full Text | References | PDF (509 KB)
  • 106 Views
  • 7 CrossRef citations
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Open Access

Review

Review Article
The role of microfluidics in protein formulations with pre-programmed functional characteristics
Hu Meng, Shuai Deng, Yajing You & Hon Fai Chan
Pages: 191-197
Published online: 07 Dec 2022
AbstractforThe role of microfluidics in protein formulations with pre-programmed functional characteristics | Full Text | References | PDF (2.6 MB)
  • 73 Views
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