Drug Development and Industrial Pharmacy, Volume 44, Issue 9 (2018)

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Drug Development and Industrial Pharmacy, Volume 44, Issue 9 (2018)

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Review Article

Review Article
Otic drug delivery systems: formulation principles and recent developments
Xu Liu, Mingshuang Li, Hugh Smyth & Feng Zhang
Pages: 1395-1408
Published online: 25 Apr 2018
AbstractforOtic drug delivery systems: formulation principles and recent developments | Full Text | References | PDF (2.1 MB)
  • 1061 Views
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Research Article

Article
Development and evaluation of a novel drug delivery: Soluplus®/TPGS mixed micelles loaded with piperine in vitro and in vivo
Yingying Ding, Changyuan Wang, Yutong Wang, Youwei Xu, Jing Zhao, Meng Gao, Yanfang Ding, Jinyong Peng & Lei Li
Pages: 1409-1416
Published online: 27 May 2018
AbstractforDevelopment and evaluation of a novel drug delivery: Soluplus®/TPGS mixed micelles loaded with piperine in vitro and in vivo | Full Text | References | PDF (1.3 MB)
  • 503 Views
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Article
Evaluation about wettability, water absorption or swelling of excipients through various methods and the correlation between these parameters and tablet disintegration
Baixue Yang, Chen Wei, Yang Yang, Qifang Wang & Sanming Li
Pages: 1417-1425
Published online: 06 Apr 2018
AbstractforEvaluation about wettability, water absorption or swelling of excipients through various methods and the correlation between these parameters and tablet disintegration | Full Text | References | PDF (2.2 MB) | Supplemental
  • 831 Views
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Article
Nifedipine di-matrix depot tablets prepared by compression coating for obtaining zero-order release
Ting Liu, Yanan Shi, Jinlong Li, Wei Jiang, Tian Yin, Yu Zhang, Haibing He, Yanjiao Wang & Xing Tang
Pages: 1426-1433
Published online: 08 Jun 2018
AbstractforNifedipine di-matrix depot tablets prepared by compression coating for obtaining zero-order release | Full Text | References | PDF (1.7 MB)
  • 183 Views
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Article
Salinomycin nanoparticles interfere with tumor cell growth and the tumor microenvironment in an orthotopic model of pancreatic cancer
Zahra Daman, Homa Faghihi & Hamed Montazeri
Pages: 1434-1442
Published online: 02 May 2018
AbstractforSalinomycin nanoparticles interfere with tumor cell growth and the tumor microenvironment in an orthotopic model of pancreatic cancer | Full Text | References | PDF (2.3 MB) | Supplemental
  • 238 Views
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Article
Novel instantly-dispersible nanocarrier powder system (IDNPs) for intranasal delivery of dapoxetine hydrochloride: in-vitro optimization, ex-vivo permeation studies, and in-vivo evaluation
Shahinaze A. Fouad, Rehab N. Shamma, Emad B. Basalious, Mohamed M. El-Nabarawi & Saadi A. Tayel
Pages: 1443-1450
Published online: 18 Apr 2018
AbstractforNovel instantly-dispersible nanocarrier powder system (IDNPs) for intranasal delivery of dapoxetine hydrochloride: in-vitro optimization, ex-vivo permeation studies, and in-vivo evaluation | Full Text | References | PDF (1.3 MB)
  • 127 Views
  • 7 CrossRef citations
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Article
Ramizol® encapsulation into extended release PLGA micro- and nanoparticle systems for subcutaneous and intramuscular administration: in vitro and in vivo evaluation
Leah Wright, Shasha Rao, Nicky Thomas, Ramiz A. Boulos & Clive A. Prestidge
Pages: 1451-1457
Published online: 11 Apr 2018
AbstractforRamizol® encapsulation into extended release PLGA micro- and nanoparticle systems for subcutaneous and intramuscular administration: in vitro and in vivo evaluation | Full Text | References | PDF (873.5 KB)
  • 438 Views
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Article
Nanocrystal-based drug delivery system of risperidone: lyophilization and characterization
Dharmesh Gol, Shreya Thakkar & Manju Misra
Pages: 1458-1466
Published online: 11 Apr 2018
AbstractforNanocrystal-based drug delivery system of risperidone: lyophilization and characterization | Full Text | References | PDF (2.1 MB)
  • 402 Views
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Article
Sublingual spray drug delivery of ketorolac-loaded chitosan nanoparticles
Sarah Baltzley, Azzam A. Malkawi, Motasem Alsmadi & Abeer M. Al-Ghananeem
Pages: 1467-1472
Published online: 12 Apr 2018
AbstractforSublingual spray drug delivery of ketorolac-loaded chitosan nanoparticles | Full Text | References | PDF (695 KB)
  • 273 Views
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Article
Improved drug loading via spray drying of a chalcone implant for local treatment of cutaneous leishmaniasis
Ariane J. Sousa-Batista, Natalia Arruda-Costa, Bartira Rossi-Bergmann & Maria Inês Ré
Pages: 1473-1480
Published online: 18 Apr 2018
AbstractforImproved drug loading via spray drying of a chalcone implant for local treatment of cutaneous leishmaniasis | Full Text | References | PDF (1.5 MB)
  • 128 Views
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Article
The absolute bioavailability and the effect of food on a new magnesium lactate dihydrate extended-release caplet in healthy subjects
Peter Dogterom, ChauHwei Fu, Thomas Legg, Yi-Jin Chiou & Steve Brandon
Pages: 1481-1487
Published online: 25 Apr 2018
AbstractforThe absolute bioavailability and the effect of food on a new magnesium lactate dihydrate extended-release caplet in healthy subjects | Full Text | References | PDF (639.3 KB)
  • 315 Views
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Article
Development of hydrogels, oleogels, and bigels as local drug delivery systems for periodontitis
Rania Hamed, Ala’a AbuRezeq & Ola Tarawneh
Pages: 1488-1497
Published online: 07 May 2018
AbstractforDevelopment of hydrogels, oleogels, and bigels as local drug delivery systems for periodontitis | Full Text | References | PDF (1.2 MB)
  • 882 Views
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Article
A long-lasting oral preformulation of the angiotensin II AT1 receptor antagonist losartan
Washington X. De Paula, Ângelo M. L. Denadai, Aline N. G. Braga, V. Prasad Shastri, Sérgio V. B. Pinheiro, Frederic Frezard, Robson A. S. Santos & Ruben D. Sinisterra
Pages: 1498-1505
Published online: 10 May 2018
AbstractforA long-lasting oral preformulation of the angiotensin II AT1 receptor antagonist losartan | Full Text | References | PDF (1.2 MB) | Supplemental
  • 129 Views
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Article
The application of SVR model in the improvement of QbD: a case study of the extraction of podophyllotoxin
Chun-Hui Zhai, Jian-Bang Xuan, Hai-Liu Fan, Teng-Fei Zhao & Jian-Lan Jiang
Pages: 1506-1511
Published online: 03 May 2018
AbstractforThe application of SVR model in the improvement of QbD: a case study of the extraction of podophyllotoxin | Full Text | References | PDF (1.1 MB)
  • 87 Views
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Article
Evaluation of non-crystalline cellulose as a novel excipient in solid dose products
Kasturi Pawar, Diane Render, Vijaya Rangari, Yoon Lee & R. Jayachandra Babu
Pages: 1512-1519
Published online: 21 May 2018
AbstractforEvaluation of non-crystalline cellulose as a novel excipient in solid dose products | Full Text | References | PDF (1.1 MB)
  • 154 Views
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Article
Mixing of low-dose cohesive drug and overcoming of pre-blending step using a new gentle-wing high-shear mixer granulator
Bader B. Alsulays, Mohamed H. Fayed, Ahmed Alalaiwe, Saad M. Alshahrani, Abdullah S. Alshetaili, Sultan M. Alshehri & Fars K. Alanazi
Pages: 1520-1527
Published online: 16 May 2018
AbstractforMixing of low-dose cohesive drug and overcoming of pre-blending step using a new gentle-wing high-shear mixer granulator | Full Text | References | PDF (1.1 MB)
  • 189 Views
  • 3 CrossRef citations
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Article
The characterization, pharmacokinetic, and tissue distribution studies of TPGS-modified artesunate liposome in rats
Cheng Hu, Kun Liang, Rui An, Xinhong Wang & Lisha You
Pages: 1528-1535
Published online: 21 Jun 2018
AbstractforThe characterization, pharmacokinetic, and tissue distribution studies of TPGS-modified artesunate liposome in rats | Full Text | References | PDF (1.4 MB)
  • 234 Views
  • 11 CrossRef citations
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Article
Preparation, characterization, and pharmacokinetics study of a novel genistein-loaded mixed micelles system
Hongxue Shen, Dandan He, Shuxia Wang, Pinggang Ding, Jianan Wang & Jianming Ju
Pages: 1536-1542
Published online: 21 Jun 2018
AbstractforPreparation, characterization, and pharmacokinetics study of a novel genistein-loaded mixed micelles system | Full Text | References | PDF (1 MB)
  • 197 Views
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Article
Does the performance of wet granulation and tablet hardness affect the drug dissolution profile of carvedilol in matrix tablets?
Darjan Košir, Tadej Ojsteršek & Franc Vrečer
Pages: 1543-1550
Published online: 14 Jun 2018
AbstractforDoes the performance of wet granulation and tablet hardness affect the drug dissolution profile of carvedilol in matrix tablets? | Full Text | References | PDF (845.4 KB)
  • 311 Views
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Article
Drug solubility in fatty acids as a formulation design approach for lipid-based formulations: a technical note
Yung-Chi Lee, Chad Dalton, Brian Regler & David Harris
Pages: 1551-1556
Published online: 22 Jun 2018
AbstractforDrug solubility in fatty acids as a formulation design approach for lipid-based formulations: a technical note | Full Text | References | PDF (1.1 MB)
  • 509 Views
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Article
Pharmacokinetics, tissue distribution, bioavailability, and excretion of nuciferine, an alkaloid from lotus, in rats by LC/MS/MS
Fugang Wang, Juan Cao, Xueqin Hou, Zhiyong Li & Xiaolan Qu
Pages: 1557-1562
Published online: 21 Jun 2018
AbstractforPharmacokinetics, tissue distribution, bioavailability, and excretion of nuciferine, an alkaloid from lotus, in rats by LC/MS/MS | Full Text | References | PDF (1,019.3 KB)
  • 212 Views
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Corrigendum

Correction
Correction to: Jake et al., Formulation and delivery strategies of ibuprofen: challenges and opportunities
Page: 1563
Published online: 08 Jun 2018
CitationforCorrection to: Jake et al., Formulation and delivery strategies of ibuprofen: challenges and opportunities | Full Text | PDF (92.8 KB)
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Free Access

Corrigenda

Correction
Correction to: Hanafy et al., Dual effect biodegradable ciprofloxacin loaded implantable matrices for osteomyelitis: controlled release and osteointegration
Page: 1564
Published online: 07 Jun 2018
CitationforCorrection to: Hanafy et al., Dual effect biodegradable ciprofloxacin loaded implantable matrices for osteomyelitis: controlled release and osteointegration | Full Text | PDF (245.9 KB)
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Free Access
Correction
Corrigendum
Page: x
Published online: 17 Jun 2018
CitationforCorrigendum | Full Text | PDF (89.8 KB)
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