Expert Opinion on Drug Discovery, Volume 14, Issue 4 (2019)

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Expert Opinion on Drug Discovery, Volume 14, Issue 4 (2019)

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Editorial

Editorial
Why have transgenic rodent models failed to successfully mimic Alzheimer’s disease. How can we develop effective drugs without them?
Rafael Franco, Eva Martínez-Pinilla & Gemma Navarro
Pages: 327-330
Published online: 18 Feb 2019
First Page PreviewforWhy have transgenic rodent models failed to successfully mimic Alzheimer’s disease. How can we develop effective drugs without them? | Full Text | References | PDF (376.7 KB) | EPUB
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Editorial
How to utilize academic research efforts in cancer drug discovery
Gervais Bérubé
Pages: 331-334
Published online: 20 Feb 2019
First Page PreviewforHow to utilize academic research efforts in cancer drug discovery | Full Text | References | PDF (377.2 KB) | EPUB
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Technology Evaluation

Article
DataWarrior: an evaluation of the open-source drug discovery tool
Edgar López-López, J. Jesús Naveja & José L. Medina-Franco
Pages: 335-341
Published online: 26 Feb 2019
AbstractforDataWarrior: an evaluation of the open-source drug discovery tool | Full Text | References | PDF (1.2 MB) | EPUB
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Review

Review
Screening drugs for myocardial disease in vivo with zebrafish: an expert update
Yanbin Zhao, Kun Zhang, Patrick Sips & Calum A. MacRae
Pages: 343-353
Published online: 06 Mar 2019
AbstractforScreening drugs for myocardial disease in vivo with zebrafish: an expert update | Full Text | References | PDF (1.2 MB) | EPUB
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Review
Modeling heart failure in animal models for novel drug discovery and development
Paul M. L. Janssen & Mohammad T. Elnakish
Pages: 355-363
Published online: 12 Mar 2019
AbstractforModeling heart failure in animal models for novel drug discovery and development | Full Text | References | PDF (714.5 KB) | EPUB
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Review
Animal models of major depressive disorder and the implications for drug discovery and development
Konstantin A. Demin, Maxim Sysoev, Maria V. Chernysh, Anna K. Savva, Mamiko Koshiba, Edina A. Wappler-Guzzetta, Cai Song, Murilo S. De Abreu, Brian Leonard, Matthew O. Parker, Brian H. Harvey, Li Tian, Eero Vasar, Tatyana Strekalova, Tamara G. Amstislavskaya, Andrey D. Volgin, Erik T. Alpyshov, Dongmei Wang & Allan V. Kalueff
Pages: 365-378
Published online: 22 Feb 2019
AbstractforAnimal models of major depressive disorder and the implications for drug discovery and development | Full Text | References | PDF (1.2 MB) | EPUB
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Review
Using miniature brain implants in rodents for novel drug discovery
Ben Waldau
Pages: 379-386
Published online: 04 Mar 2019
AbstractforUsing miniature brain implants in rodents for novel drug discovery | Full Text | References | PDF (1,004.8 KB) | EPUB
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Review
Carbohydrate–protein interactions and multivalency: implications for the inhibition of influenza A virus infections
Wenjing Lu & Roland J. Pieters
Pages: 387-395
Published online: 05 Feb 2019
AbstractforCarbohydrate–protein interactions and multivalency: implications for the inhibition of influenza A virus infections | Full Text | References | PDF (1.2 MB) | EPUB
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Review
Broad-spectrum coronavirus antiviral drug discovery
Allison L. Totura & Sina Bavari
Pages: 397-412
Published online: 08 Mar 2019
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