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Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 1, Issue 2 (2005)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 1, Issue 2 (2005)

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Review

Article

Caco-2 cell permeability assays to measure drug absorption

Richard B van Breemen & Yongmei Li

Pages: 175-185

Published online: 16 Aug 2005

AbstractforCaco-2 cell permeability assays to measure drug absorption | References | PDF (276.7 KB)

5192 Views
378 CrossRef citations
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Article

Cytochrome P450 interactions in human cancers: new aspects considering CYP1B1

Peter H Roos & Hermann M Bolt

Pages: 187-202

Published online: 16 Aug 2005

AbstractforCytochrome P450 interactions in human cancers: new aspects considering CYP1B1 | References | PDF (296.4 KB)

208 Views
74 CrossRef citations
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Article

The influence of long-term treatment with psychotropic drugs on cytochrome P450: the involvement of different mechanisms

Włladyslława Anna Daniel

Pages: 203-217

Published online: 16 Aug 2005

AbstractforThe influence of long-term treatment with psychotropic drugs on cytochrome P450: the involvement of different mechanisms | References | PDF (217.9 KB)

68 Views
34 CrossRef citations
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Article

Metabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance

Nicole HP Cnubben, Heleen M Wortelboer, Jelmer J van Zanden, Ivonne MCM Rietjens & Peter J van Bladeren

Pages: 219-232

Published online: 16 Aug 2005

AbstractforMetabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance | References | PDF (229.6 KB)

98 Views
14 CrossRef citations
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Article

Expression and function of multidrug resistance transporters at the blood–brain barriers

Jean-Michel Scherrmann

Pages: 233-246

Published online: 16 Aug 2005

AbstractforExpression and function of multidrug resistance transporters at the blood–brain barriers | References | PDF (236.1 KB)

186 Views
44 CrossRef citations
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Article

Gene expression profiling for pharmaceutical safety assessment

Russell Huby & Jonathan D Tugwood

Pages: 247-260

Published online: 16 Aug 2005

AbstractforGene expression profiling for pharmaceutical safety assessment | References | PDF (1.1 MB)

44 Views
9 CrossRef citations
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Article

Genotoxicity screening: the slow march to the future

Richard M Walmsley

Pages: 261-268

Published online: 16 Aug 2005

AbstractforGenotoxicity screening: the slow march to the future | References | PDF (135.9 KB)

48 Views
16 CrossRef citations
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Drug Evaluation

Article

Clinical pharmacology of etoricoxib

Marta L Capone, Stefania Tacconelli & Paola Patrignani

Pages: 269-282

Published online: 16 Aug 2005

AbstractforClinical pharmacology of etoricoxib | References | PDF (289.7 KB)

240 Views
13 CrossRef citations
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Article

Sildenafil: efficacy, safety, tolerability and mechanism of action in treating erectile dysfunction

Sharron H Francis & Jackie D Corbin

Pages: 283-293

Published online: 16 Aug 2005

AbstractforSildenafil: efficacy, safety, tolerability and mechanism of action in treating erectile dysfunction | References | PDF (201.6 KB)

785 Views
34 CrossRef citations
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Article

Potency and selectivity of vardenafil: a phosphodiesterase Type 5 inhibitor

Frank Sommer

Pages: 295-301

Published online: 16 Aug 2005

AbstractforPotency and selectivity of vardenafil: a phosphodiesterase Type 5 inhibitor | References | PDF (127.7 KB)

68 Views
4 CrossRef citations
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Technology Evaluation

Article

Computational prediction of human drug metabolism

Sean Ekins, Sergey Andreyev, Andy Ryabov, Eugene Kirillov, Eugene A Rakhmatulin, Andrej Bugrim & Tatiana Nikolskaya

Pages: 303-324

Published online: 16 Aug 2005

AbstractforComputational prediction of human drug metabolism | References | PDF (2.4 MB)

240 Views
69 CrossRef citations
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Article

The rise of PAMPA

Alex Avdeef

Pages: 325-342

Published online: 16 Aug 2005

AbstractforThe rise of PAMPA | References | PDF (897.9 KB)

982 Views
164 CrossRef citations
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