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Volume 19, Issue 4

Expert Opinion on Therapeutic Targets

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 4 (2015)

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 4 (2015)

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Editorial

Gene expression signatures as a therapeutic target for severe H7N9 influenza – what do we know so far?

Juliet Morrison & Michael G Katze

Pages: 447-450

Published online: 20 Jan 2015

AbstractforGene expression signatures as a therapeutic target for severe H7N9 influenza – what do we know so far? | Full Text | References | PDF (255 KB)

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Free Access

Editorial

The potential of targeting Ras proteins in lung cancer

Frank McCormick PhD

Pages: 451-454

Published online: 06 Jan 2015

AbstractforThe potential of targeting Ras proteins in lung cancer | Full Text | References | PDF (206.6 KB)

1409 Views
15 CrossRef citations
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Original Research

Article

Transcriptional regulation of Mcl-1 plays an important role of cellular protective effector of vincristine-triggered autophagy in oral cancer cells

Ming-Ju Hsieh, Yi-Hsien Hsieh, Chiao-Wen Lin, Mu-Kuan Chen, Shun-Fa Yang & Hui-Ling Chiou

Pages: 455-470

Published online: 22 Jan 2015

AbstractforTranscriptional regulation of Mcl-1 plays an important role of cellular protective effector of vincristine-triggered autophagy in oral cancer cells | Full Text | References | PDF (1.2 MB)

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Article

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer’s disease and multiple sclerosis

Mythily Srinivasan (Associate Professor) MS PhD & Debomoy K Lahiri (Professor of Medical Neurosciences) PhD

Pages: 471-487

Published online: 04 Feb 2015

AbstractforSignificance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer’s disease and multiple sclerosis | Full Text | References | PDF (1.4 MB)

738 Views
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Review

MicroRNAs as therapeutic targets in atherosclerosis

Xavier Loyer PhD, Ziad Mallat MD PhD, Chantal M Boulanger PharmD PhD & Alain Tedgui PhD

Pages: 489-496

Published online: 03 Dec 2014

AbstractforMicroRNAs as therapeutic targets in atherosclerosis | Full Text | References | PDF (298.2 KB)

688 Views
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Targeting microglia for the treatment of Alzheimer’s disease

Patrick L McGeer & Edith G McGeer

Pages: 497-506

Published online: 29 Nov 2014

AbstractforTargeting microglia for the treatment of Alzheimer’s disease | Full Text | References | PDF (461.7 KB)

1466 Views
66 CrossRef citations
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Targeting defective Toll-like receptor-3 function and idiopathic pulmonary fibrosis

David N O’Dwyer MB PhD, Michelle E Armstrong PhD, Minesh Kooblall MB & Seamas C Donnelly MD

Pages: 507-514

Published online: 22 Dec 2014

AbstractforTargeting defective Toll-like receptor-3 function and idiopathic pulmonary fibrosis | Full Text | References | PDF (314.8 KB)

474 Views
21 CrossRef citations
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Novel molecular targets for urothelial carcinoma

Bishoy M Faltas MD, Beerinder S Karir MD, Scott T Tagawa MD & Jonathan E Rosenberg MD

Pages: 515-525

Published online: 30 Jan 2015

AbstractforNovel molecular targets for urothelial carcinoma | Full Text | References | PDF (283.2 KB)

245 Views
7 CrossRef citations
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Adipose tissue macrophages: the inflammatory link between obesity and cancer?

Marek Wagner, Eli Sihn Samdal Steinskog & Helge Wiig

Pages: 527-538

Published online: 04 Dec 2014

AbstractforAdipose tissue macrophages: the inflammatory link between obesity and cancer? | Full Text | References | PDF (370.1 KB)

719 Views
28 CrossRef citations
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FAK/Src family of kinases: protective or aggravating factor for ischemia reperfusion injury in nervous system?

Christos Bikis MD, Demetrios Moris MD, Ioanna Vasileiou MD PhD, Eustratios Patsouris MD PhD & Stamatios Theocharis MD PhD

Pages: 539-549

Published online: 04 Dec 2014

AbstractforFAK/Src family of kinases: protective or aggravating factor for ischemia reperfusion injury in nervous system? | Full Text | References | PDF (320.1 KB)

295 Views
3 CrossRef citations
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The η-class carbonic anhydrases as drug targets for antimalarial agents

Claudiu T Supuran & Clemente Capasso

Pages: 551-563

Published online: 12 Dec 2014

AbstractforThe η-class carbonic anhydrases as drug targets for antimalarial agents | Full Text | References | PDF (832.6 KB)

192 Views
146 CrossRef citations
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Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target?

Jo Nijs, Mira Meeus, Jan Versijpt, Maarten Moens, Inge Bos, Kristel Knaepen & Romain Meeusen

Pages: 565-576

Published online: 18 Dec 2014

AbstractforBrain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target? | Full Text | References | PDF (301.5 KB)

2460 Views
121 CrossRef citations
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