Future Medicinal Chemistry, Volume 14, Issue 11 (2022)

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Future Medicinal Chemistry, Volume 14, Issue 11 (2022)

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Editorial

Editorial
Rapidly Evolving First-Line Therapy Using Checkpoint Inhibitors in Metastatic Renal Cell Cancer
Jeanny B Aragon-Ching
Pages: 767-770
Published online: 28 Apr 2022
First Page PreviewforRapidly Evolving First-Line Therapy Using Checkpoint Inhibitors in Metastatic Renal Cell Cancer | Full Text | References | PDF (180.1 KB) | EPUB
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Research Article

Article
Factorial Design in the Optimization and Study ‘in combo’ of Derivatives of imidazo[1,2-a]azines in the COX´s Isoforms Inhibition
Miguel Guerrero-González, María-Elena Campos Aldrete & Marco Antonio Meraz-Rios
Pages: 771-784
Published online: 10 May 2022
AbstractforFactorial Design in the Optimization and Study ‘in combo’ of Derivatives of imidazo[1,2-a]azines in the COX´s Isoforms Inhibition | Full Text | References | PDF (2.9 MB) | EPUB
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Article
Structural Insight Into SSE15206 in Complex With Tubulin Provides a Rational Design for Pyrazolinethioamides As Tubulin Polymerization Inhibitors
Lingling Ma, Jiahong Lei, Hai Chen, Ridong Huang, Tao Su, Jianrong Feng & Qiu Sun
Pages: 785-794
Published online: 04 May 2022
AbstractforStructural Insight Into SSE15206 in Complex With Tubulin Provides a Rational Design for Pyrazolinethioamides As Tubulin Polymerization Inhibitors | Full Text | References | PDF (9.9 MB) | EPUB | Supplemental
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Article
Novel Trypanocidal Thiophen-Chalcone Cruzain Inhibitors: Structure- and Ligand-Based Studies
Aldo S de Oliveira, Marilia Valli, Leonardo LG Ferreira, Julia M Souza, Renata Krogh, Lidiane Meier, Heitor R Abreu, Bruna G Voltolini, Luana C Llanes, Ricardo J Nunes, Antonio L Braga & Adriano D Andricopulo
Pages: 795-808
Published online: 11 May 2022
AbstractforNovel Trypanocidal Thiophen-Chalcone Cruzain Inhibitors: Structure- and Ligand-Based Studies | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
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Review

Review Article
Therapeutic Potential of Vitamin B1 Derivative Benfotiamine From Diabetes to COVID-19
Kieran V Allowitz, John J Yoo, Justin R Taylor, Omar A Baloch, Kyra Harames & Kota V Ramana
Pages: 809-826
Published online: 10 May 2022
AbstractforTherapeutic Potential of Vitamin B1 Derivative Benfotiamine From Diabetes to COVID-19 | Full Text | References | PDF (1.6 MB) | EPUB
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Review Article
An Emerging Role of KRAS in Biogenesis, Cargo Sorting and Uptake of Cancer-Derived Extracellular Vesicles
Zhijack Fong & Wai-Leng Lee
Pages: 827-845
Published online: 03 May 2022
AbstractforAn Emerging Role of KRAS in Biogenesis, Cargo Sorting and Uptake of Cancer-Derived Extracellular Vesicles | Full Text | References | PDF (854.6 KB) | EPUB | Supplemental
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