Future Medicinal Chemistry, Volume 2, Issue 6 (2010)

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Future Medicinal Chemistry, Volume 2, Issue 6 (2010)

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Editorial

Editorial
Role of Open Chemical Data in Aiding Drug Discovery and Design
Anna Gaulton & John P Overington
Pages: 903-907
Published online: 14 Jun 2010
First Page PreviewforRole of Open Chemical Data in Aiding Drug Discovery and Design | Full Text | References | PDF (811.3 KB)
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Editorial
Bringing Ion Channel Crystal Structures into Sharper Focus with Computer Modeling: Examples from Mechanosensitive Channels
Donald E Elmore
Pages: 909-913
Published online: 14 Jun 2010
First Page PreviewforBringing Ion Channel Crystal Structures into Sharper Focus with Computer Modeling: Examples from Mechanosensitive Channels | Full Text | References | PDF (627.8 KB)
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Commentary

Editorial
Evolution of Solid-State Nmr in Pharmaceutical Analysis
Frederick G Vogt
Pages: 915-921
Published online: 14 Jun 2010
AbstractforEvolution of Solid-State Nmr in Pharmaceutical Analysis | Full Text | References | PDF (800.8 KB)
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Editorial
The Role of Pharmacokinetic and Pharmacokinetic/Pharmacodynamic Modeling in Drug Discovery and Development
Xiang-Qing Yu & Alan G E Wilson
Pages: 923-928
Published online: 14 Jun 2010
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News & Analysis

News
News & Analysis
Pages: 929-932
Published online: 14 Jun 2010
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News
Institutional Profile: Crystal Structure Information in Drug Discovery and Development: Current Perspectives and New Possibilities from the Cambridge Crystallographic Data Centre
Colin R Groom & Frank H Allen
Pages: 933-939
Published online: 14 Jun 2010
First Page PreviewforInstitutional Profile: Crystal Structure Information in Drug Discovery and Development: Current Perspectives and New Possibilities from the Cambridge Crystallographic Data Centre | Full Text | References | PDF (683.4 KB)
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News
Research Spotlight: The Cooperative Research Centre for Cancer Therapeutics: Bridging the Gap Between Leading Cancer Research at Australia’s Universities and Developing Novel Cancer Drugs
Jonathan B Baell, Guy Heathers & Cathy Sage
Pages: 941-947
Published online: 14 Jun 2010
AbstractforResearch Spotlight: The Cooperative Research Centre for Cancer Therapeutics: Bridging the Gap Between Leading Cancer Research at Australia’s Universities and Developing Novel Cancer Drugs | Full Text | References | PDF (3.6 MB)
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Perspective

Article
Strategies for Discovering and Derisking Covalent, Irreversible Enzyme Inhibitors
Douglas S Johnson, Eranthie Weerapana & Benjamin F Cravatt
Pages: 949-964
Published online: 14 Jun 2010
AbstractforStrategies for Discovering and Derisking Covalent, Irreversible Enzyme Inhibitors | Full Text | References | PDF (4.1 MB)
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Special Report

Article
Directed Embryonic Stem Cell Differentiation with Small Molecules
Shoutian Zhu, Heiko Wurdak & Peter G Schultz
Pages: 965-973
Published online: 14 Jun 2010
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Review

Review Article
Applications of Molecular Mri and Optical Imaging in Cancer
Marie-France Penet, Maria Mikhaylova, Cong Li, Balaji Krishnamachary, Kristine Glunde, Arvind P Pathak & Zaver M Bhujwalla
Pages: 975-988
Published online: 14 Jun 2010
AbstractforApplications of Molecular Mri and Optical Imaging in Cancer | Full Text | References | PDF (3.5 MB)
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Review Article
Using Peptides to Study Protein–Protein Interactions
Hadar Benyamini & Assaf Friedler
Pages: 989-1003
Published online: 14 Jun 2010
AbstractforUsing Peptides to Study Protein–Protein Interactions | Full Text | References | PDF (1.9 MB)
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Review Article
Paradigm Shift in Discovering Next-Generation Anti-Infective Agents: Targeting Quorum Sensing, C-Di-Gmp Signaling and Biofilm Formation in Bacteria with Small Molecules
Herman O Sintim, Jacqueline A I Smith, Jingxin Wang, Shizuka Nakayama & Lei Yan
Pages: 1005-1035
Published online: 14 Jun 2010
AbstractforParadigm Shift in Discovering Next-Generation Anti-Infective Agents: Targeting Quorum Sensing, C-Di-Gmp Signaling and Biofilm Formation in Bacteria with Small Molecules | Full Text | References | PDF (6.7 MB)
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Erratum

Correction
Erratum
Pages: 1047-1048
Published online: 14 Jun 2010
CitationforErratum | Full Text | PDF (327.2 KB)
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