Future Medicinal Chemistry, Volume 6, Issue 11 (2014)

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Future Medicinal Chemistry, Volume 6, Issue 11 (2014)

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Editorial

Editorial
The Role of Pharmacokinetic Studies in Drug Discovery: Where are We Now, How Did We Get Here and Where are We Going?
Peter JH Webborn
Pages: 1233-1235
Published online: 27 Aug 2014
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Editorial
Challenges in Developing Novel DNA Methyltransferases Inhibitors for Cancer Therapy
Dominique Guianvarc’h & Paola Barbara Arimondo
Pages: 1237-1240
Published online: 27 Aug 2014
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Editorial
NDRG1 As A Molecular Target to Inhibit the Epithelial–Mesenchymal Transition: The Case for Developing Inhibitors of Metastasis
Sumit Sahni, Sukriti Krishan & Des R Richardson
Pages: 1241-1244
Published online: 27 Aug 2014
First Page PreviewforNDRG1 As A Molecular Target to Inhibit the Epithelial–Mesenchymal Transition: The Case for Developing Inhibitors of Metastasis | Full Text | References | PDF (873.6 KB)
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News & Analysis

News
News & Analysis
Pages: 1245-1247
Published online: 27 Aug 2014
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Research Article

Article
Preclinical Activity of Multiple-Target Gold(III)-Dithiocarbamato Peptidomimetics in Prostate Cancer Cells and Xenografts
Marta Celegato, Dolores Fregona, Maurizio Mongiat, Luca Ronconi, Cinzia Borghese, Vincenzo Canzonieri, Naike Casagrande, Chiara Nardon, Alfonso Colombatti & Donatella Aldinucci
Pages: 1249-1263
Published online: 27 Aug 2014
AbstractforPreclinical Activity of Multiple-Target Gold(III)-Dithiocarbamato Peptidomimetics in Prostate Cancer Cells and Xenografts | Full Text | References | PDF (2.2 MB)
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Perspective

Review Article
The Essential Roles of Chemistry in High-Throughput Screening Triage
Jayme L Dahlin & Michael A Walters
Pages: 1265-1290
Published online: 27 Aug 2014
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Review

Review Article
Focused Chemical Libraries – Design and Enrichment: An Example of Protein–Protein Interaction Chemical Space
Xu Zhang, Stéphane Betzi, Xavier Morelli & Philippe Roche
Pages: 1291-1307
Published online: 27 Aug 2014
AbstractforFocused Chemical Libraries – Design and Enrichment: An Example of Protein–Protein Interaction Chemical Space | Full Text | References | PDF (2.9 MB)
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Review Article
Unnatural Amino Acids in Novel Antibody Conjugates
Trevor J Hallam & Vaughn V Smider
Pages: 1309-1324
Published online: 27 Aug 2014
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Review Article
Activators of AMPK: Not Just for Type II Diabetes
Ilana Zaks, Tamar Getter & Arie Gruzman
Pages: 1325-1353
Published online: 27 Aug 2014
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Review Article
The Current Stage of Cathepsin B Inhibitors As Potential Anticancer Agents
Janko Kos, Ana Mitrović & Bojana Mirković
Pages: 1355-1371
Published online: 27 Aug 2014
AbstractforThe Current Stage of Cathepsin B Inhibitors As Potential Anticancer Agents | Full Text | References | PDF (2 MB)
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