Leukemia & Lymphoma, Volume 53, Issue 9 (2012)

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Leukemia & Lymphoma, Volume 53, Issue 9 (2012)

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Commentary on selected articles in this issue

Article Commentary
Monoclonal B-lymphocytosis: reflections and definitions
Stephen P. Mulligan
Pages: 1647-1650
Published online: 23 Apr 2012
First Page PreviewforMonoclonal B-lymphocytosis: reflections and definitions | Full Text | References | PDF (161.4 KB) | Supplemental
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Commentary

Article Commentary
Chronic myeloid leukemia and risk of second malignancy in two eras of treatment
Brady L. Stein
Pages: 1651-1653
Published online: 16 Mar 2012
First Page PreviewforChronic myeloid leukemia and risk of second malignancy in two eras of treatment | Full Text | References | PDF (136.8 KB) | Supplemental
  • 1008 Views
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Article Commentary
Keeping good and bad company: stromal cells in lymphoma
Jan Delabie
Pages: 1654-1655
Published online: 09 Jul 2012
CitationforKeeping good and bad company: stromal cells in lymphoma | Full Text | References | PDF (135.8 KB) | Supplemental
  • 647 Views
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Article Commentary
The spectrum of monoclonal gammopathies affecting the kidney
Nelson Leung & Morie A. Gertz
Pages: 1656-1657
Published online: 04 May 2012
CitationforThe spectrum of monoclonal gammopathies affecting the kidney | Full Text | References | PDF (128.4 KB) | Supplemental
  • 982 Views
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Article Commentary
Pioneering studies of histone deacetylase inhibitors in myeloma: signals of activity set the stage for combination therapy trials
H. Miles Prince
Pages: 1658-1659
Published online: 13 Feb 2012
CitationforPioneering studies of histone deacetylase inhibitors in myeloma: signals of activity set the stage for combination therapy trials | Full Text | References | PDF (126.7 KB)
  • 534 Views
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Review

Review Article
Monoclonal B-cell lymphocytosis: a reappraisal of its clinical implications
Stefano Molica, Francesca Romana Mauro, Matteo Molica, Ilaria Del Giudice & Robin Foà
Pages: 1660-1665
Published online: 16 Mar 2012
AbstractforMonoclonal B-cell lymphocytosis: a reappraisal of its clinical implications | Full Text | References | PDF (223 KB) | Supplemental
  • 510 Views
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Review Article

Review Article
The role of natural killer cells in immunity against multiple myeloma
James Godfrey & Don M. Benson Jr
Pages: 1666-1676
Published online: 19 Apr 2012
AbstractforThe role of natural killer cells in immunity against multiple myeloma | Full Text | References | PDF (268.7 KB) | Supplemental
  • 1718 Views
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Original Articles: Clinical

Article
Association between obesity at diagnosis and weight change during induction and survival in pediatric acute lymphoblastic leukemia
Marie-Chantal Ethier, Sarah Alexander, Oussama Abla, Gloria Green, Renita Lam & Lillian Sung
Pages: 1677-1681
Published online: 26 Mar 2012
AbstractforAssociation between obesity at diagnosis and weight change during induction and survival in pediatric acute lymphoblastic leukemia | Full Text | References | PDF (179.6 KB) | Supplemental
  • 458 Views
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Research Article

Article
Asparagine and aspartic acid concentrations in bone marrow versus peripheral blood during Berlin–Frankfurt–Münster-based induction therapy for childhood acute lymphoblastic leukemia
Manuel Steiner, Daniela Hochreiter, David C. Kasper, Rosa Kornmüller, Herbert Pichler, Oskar A. Haas, Ulrike Pötschger, Caroline Hutter, Michael N. Dworzak, Georg Mann & Andishe Attarbaschi
Pages: 1682-1687
Published online: 18 Apr 2012
AbstractforAsparagine and aspartic acid concentrations in bone marrow versus peripheral blood during Berlin–Frankfurt–Münster-based induction therapy for childhood acute lymphoblastic leukemia | Full Text | References | PDF (209.5 KB) | Supplemental
  • 273 Views
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Article
A common variant near TERC and telomere length are associated with susceptibility to childhood acute lymphoblastic leukemia in Chinese
Xiaojing Sheng, Limei Zhang, Dewei Luo, Na Tong, Meilin Wang, Yongjun Fang, Jie Li & Zhengdong Zhang
Pages: 1688-1692
Published online: 26 Mar 2012
AbstractforA common variant near TERC and telomere length are associated with susceptibility to childhood acute lymphoblastic leukemia in Chinese | Full Text | References | PDF (182.1 KB) | Supplemental
  • 197 Views
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Article
Clofarabine, cyclophosphamide and etoposide for the treatment of relapsed or resistant acute leukemia in pediatric patients
Maurizio Miano, Angela Pistorio, Maria C. Putti, Carlo Dufour, Chiara Messina, Elena Barisone, Ottavio Ziino, Rosanna Parasole, Matteo Luciani, Luca Lo Nigro, Giulio De Rossi, Stefania Varotto, Nicoletta Bertorello, Fara Petruzziello, Michaela Calvillo & Concetta Micalizzi
Pages: 1693-1698
Published online: 13 Mar 2012
AbstractforClofarabine, cyclophosphamide and etoposide for the treatment of relapsed or resistant acute leukemia in pediatric patients | Full Text | References | PDF (265.8 KB) | Supplemental
  • 2687 Views
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Article
Allogeneic hematopoietic stem cell transplant with reduced-intensity conditioning for chronic lymphocytic leukemia in Sweden: does donor T-cell engraftment 3 months after transplant predict survival?
Maciej Machaczka, Jan-Erik Johansson, Mats Remberger, Helene Hallböök, Claes Malm, Vladimir Lj Lazarevic, Anders Wahlin, Hamdy Omar, Gunnar Juliusson, Eva Kimby & Hans Hägglund
Pages: 1699-1705
Published online: 16 Mar 2012
AbstractforAllogeneic hematopoietic stem cell transplant with reduced-intensity conditioning for chronic lymphocytic leukemia in Sweden: does donor T-cell engraftment 3 months after transplant predict survival? | Full Text | References | PDF (331.7 KB) | Supplemental
  • 256 Views
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Article
Secondary malignancy after imatinib therapy: eight cases and review of the literature
Berna Bozkurt Duman, Semra Paydas, Umut Disel, Ayberk Besen & Emel Gurkan
Pages: 1706-1708
Published online: 02 Apr 2012
AbstractforSecondary malignancy after imatinib therapy: eight cases and review of the literature | Full Text | References | PDF (150.9 KB) | Supplemental
  • 584 Views
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Article
Bcl2-interacting killer CpG methylation in multiple myeloma: a potential predictor of relapsed/refractory disease with therapeutic implications
Eleftheria Hatzimichael, Aggeliki Dasoula, Valentinos Kounnis, Leonidas Benetatos, Cristiana Lo Nigro, Laura Lattanzio, Alexandra Papoudou-Bai, George Dranitsaris, Evangelos Briasoulis & Tim Crook
Pages: 1709-1713
Published online: 13 Mar 2012
AbstractforBcl2-interacting killer CpG methylation in multiple myeloma: a potential predictor of relapsed/refractory disease with therapeutic implications | Full Text | References | PDF (209.2 KB) | Supplemental
  • 234 Views
  • 12 CrossRef citations
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Article
Efficacy, safety and quality-of-life associated with lenalidomide plus dexamethasone for the treatment of relapsed or refractory multiple myeloma: the Spanish experience
Adrian Alegre, Albert Oriol-Rocafiguera, Jose Garcia-Larana, Maria-Victoria Mateos, Anna Sureda, Carmen Martinez-Chamorro, Maria Teresa Cibeira, Beatriz Aguado, Robert Knight & Barbara Rosettani
Pages: 1714-1721
Published online: 01 Mar 2012
AbstractforEfficacy, safety and quality-of-life associated with lenalidomide plus dexamethasone for the treatment of relapsed or refractory multiple myeloma: the Spanish experience | Full Text | References | PDF (392.7 KB) | Supplemental
  • 1307 Views
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Article
Phase II study of melphalan, thalidomide and prednisone combined with oral panobinostat in patients with relapsed/refractory multiple myeloma
Massimo Offidani, Claudia Polloni, Federica Cavallo, Anna Marina Liberati, Stelvio Ballanti, Stefano Pulini, Massimo Catarini, Francesco Alesiani, Laura Corvatta, Silvia Gentili, Patrizia Caraffa, Mario Boccadoro, Pietro Leoni & Antonio Palumbo
Pages: 1722-1727
Published online: 16 Mar 2012
AbstractforPhase II study of melphalan, thalidomide and prednisone combined with oral panobinostat in patients with relapsed/refractory multiple myeloma | Full Text | References | PDF (196.5 KB) | Supplemental
  • 737 Views
  • 39 CrossRef citations
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Article
Thalidomide consolidation improves progression-free survival in myeloma with normal but not up-regulated expression of fibroblast growth factor receptor 3: analysis from the Australasian Leukaemia and Lymphoma Group MM6 clinical trial
P. Joy Ho, Ross D. Brown, Andrew Spencer, Melinda Jeffels, Daniel Daniher, John Gibson & Douglas E. Joshua
Pages: 1728-1734
Published online: 13 Mar 2012
AbstractforThalidomide consolidation improves progression-free survival in myeloma with normal but not up-regulated expression of fibroblast growth factor receptor 3: analysis from the Australasian Leukaemia and Lymphoma Group MM6 clinical trial | Full Text | References | PDF (390.5 KB) | Supplemental
  • 419 Views
  • 4 CrossRef citations
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Article
Association of interleukin-6 and interleukin-8 with poor prognosis in elderly patients with chronic lymphocytic leukemia
Ju-Yoon Yoon, Sandrine Lafarge, Dave Dawe, Sunjay Lakhi, Rajat Kumar, Carmen Morales, Aaron Marshall, Spencer B. Gibson & James B. Johnston
Pages: 1735-1742
Published online: 04 Apr 2012
AbstractforAssociation of interleukin-6 and interleukin-8 with poor prognosis in elderly patients with chronic lymphocytic leukemia | Full Text | References | PDF (381.9 KB) | Supplemental
  • 406 Views
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Article
Variations of the ataxia telangiectasia mutated gene in patients with chronic lymphocytic leukemia lack substantial impact on progression-free survival and overall survival: a Cancer and Leukemia Group B study
Gerard Lozanski, Amy S. Ruppert, Nyla A. Heerema, Arletta Lozanski, David M. Lucas, Amber Gordon, John G. Gribben, Vicki A. Morrison, Kanti M. Rai, Guido Marcucci, Richard A. Larson & John C. Byrd
Pages: 1743-1748
Published online: 02 Jun 2012
AbstractforVariations of the ataxia telangiectasia mutated gene in patients with chronic lymphocytic leukemia lack substantial impact on progression-free survival and overall survival: a Cancer and Leukemia Group B study | Full Text | References | PDF (257.6 KB) | Supplemental
  • 255 Views
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Article
Richter transformation in 16 of 149 Chinese patients with chronic lymphocytic leukemia
Lei Fan, Li Wang, Run Zhang, Cheng Fang, Dan-Xia Zhu, Yin-Hua Wang, Zhi-Jian Zou, Jian-Yong Li & Wei Xu
Pages: 1749-1756
Published online: 13 Mar 2012
AbstractforRichter transformation in 16 of 149 Chinese patients with chronic lymphocytic leukemia | Full Text | References | PDF (185.1 KB)
  • 333 Views
  • 18 CrossRef citations
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Article
Absolute lymphocyte count at day + 21 predicts survival in patients with early-stage diffuse large B-cell lymphoma treated with rituximab, cyclophosphamide, adriamycin, vincristine and prednisone
Yee Soo Chae, Hocheol Shin, Sang Kyun Sohn, Soo Jung Lee, Joon Ho Moon, Byung Woog Kang, Jong Gwang Kim, Deok-Hwan Yang, Je-Jung Lee & Tae In Park
Pages: 1757-1763
Published online: 19 Apr 2012
AbstractforAbsolute lymphocyte count at day + 21 predicts survival in patients with early-stage diffuse large B-cell lymphoma treated with rituximab, cyclophosphamide, adriamycin, vincristine and prednisone | Full Text | References | PDF (404.6 KB) | Supplemental
  • 221 Views
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Original Articles: Research

Article
Gene expression profiling indicates that immunohistochemical expression of CD40 is a marker of an inflammatory reaction in the tumor stroma of diffuse large B-cell lymphoma
Karin Rydström, Patrick Joost, Mats Ehinger, Patrik Edén, Mats Jerkeman, Eva Cavallin-Ståhl & Johan Linderoth
Pages: 1764-1768
Published online: 16 Mar 2012
AbstractforGene expression profiling indicates that immunohistochemical expression of CD40 is a marker of an inflammatory reaction in the tumor stroma of diffuse large B-cell lymphoma | Full Text | References | PDF (237.7 KB) | Supplemental
  • 216 Views
  • 11 CrossRef citations
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Research Article

Article
Hyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia
Na Shao, Jie Zou, Jie Li, Feng Chen, Jianjian Dai, Xun Qu, Xiulian Sun, Daoxin Ma & Chunyan Ji
Pages: 1769-1778
Published online: 13 Mar 2012
AbstractforHyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia | Full Text | References | PDF (585 KB) | Supplemental
  • 359 Views
  • 16 CrossRef citations
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Article
Statin-dependent activation of protein kinase Cδ in acute promyelocytic leukemia cells and induction of leukemic cell differentiation
Antonella Sassano, Jessica K. Altman, Leo I. Gordon & Leonidas C. Platanias
Pages: 1779-1784
Published online: 19 Apr 2012
AbstractforStatin-dependent activation of protein kinase Cδ in acute promyelocytic leukemia cells and induction of leukemic cell differentiation | Full Text | References | PDF (314.2 KB) | Supplemental
  • 230 Views
  • 12 CrossRef citations
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Article
Expansion of effector T cells associated with decreased PD-1 expression in patients with indolent B cell lymphomas and chronic lymphocytic leukemia
Sanne H. Tonino, Pablo J. van de Berg, Si La Yong, Ineke J. Ten Berge, Marie José Kersten, René A. W. van Lier, Marinus H. van Oers & Arnon P. Kater
Pages: 1785-1794
Published online: 19 Apr 2012
AbstractforExpansion of effector T cells associated with decreased PD-1 expression in patients with indolent B cell lymphomas and chronic lymphocytic leukemia | Full Text | References | PDF (500.2 KB) | Supplemental
  • 606 Views
  • 28 CrossRef citations
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Article
Activation of human leukemic mast cell line LAD2 is modulated by dehydroleucodine and xanthatin
Mariano E. Vera, Fabio A. Persia, María L. Mariani, María I. Rudolph, Teresa H. Fogal, Juan P. Ceñal, Laura S. Favier, Carlos E. Tonn & Alicia B. Penissi
Pages: 1795-1803
Published online: 29 May 2012
AbstractforActivation of human leukemic mast cell line LAD2 is modulated by dehydroleucodine and xanthatin | Full Text | References | PDF (565.8 KB) | Supplemental
  • 378 Views
  • 13 CrossRef citations
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Letters to the Editor

Letter
Renal Fanconi syndrome as a cause of chronic kidney disease in patients with monoclonal gammopathy of undetermined significance: partially reversed renal function by high-dose dexamethasone with bortezomib
Yuki Nishida, Kan-ichi Iwama, Masayuki Yamakura, Masami Takeuchi & Kosei Matsue
Pages: 1804-1806
Published online: 19 Apr 2012
First Page PreviewforRenal Fanconi syndrome as a cause of chronic kidney disease in patients with monoclonal gammopathy of undetermined significance: partially reversed renal function by high-dose dexamethasone with bortezomib | Full Text | References | PDF (895.5 KB) | Supplemental
  • 280 Views
  • 10 CrossRef citations
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Letter

Letter
Reciprocal changes in regulatory T cells and Th17 helper cells induced by exercise in patients with chronic lymphocytic leukemia
Chava Perry, Yair Herishanu, Inbal Hazan-Halevy, Sigi Kay, Nir Bdolach, Elizabeth Naparstek, Aaron Polliack & Dan Grisaru
Pages: 1807-1810
Published online: 13 Feb 2012
First Page PreviewforReciprocal changes in regulatory T cells and Th17 helper cells induced by exercise in patients with chronic lymphocytic leukemia | Full Text | References | PDF (280.8 KB) | Supplemental
  • 388 Views
  • 15 CrossRef citations
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Letter
Waldenstrom macroglobulinemia with a durable clinical response to epoetin beta
Christopher Parrish & Roger G. Owen
Pages: 1811-1813
Published online: 01 Mar 2012
First Page PreviewforWaldenstrom macroglobulinemia with a durable clinical response to epoetin beta | Full Text | References | PDF (181 KB) | Supplemental
  • 92 Views
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Letter
Interfollicular Hodgkin lymphoma in children: an uncommon mimicker of reactive lymphadenopathy
Mariana M. Cajaiba & Samir B. Kahwash
Pages: 1814-1816
Published online: 21 Feb 2012
First Page PreviewforInterfollicular Hodgkin lymphoma in children: an uncommon mimicker of reactive lymphadenopathy | Full Text | References | PDF (287.5 KB) | Supplemental
  • 295 Views
  • 4 CrossRef citations
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Letter
Specific p53 mutations do not impact results of alemtuzumab therapy among patients with chronic lymphocytic leukemia
Michael Doubek, Martin Trbušek, Jitka Malčíková, Yvona Brychtová, Jana Šmardová, Jana Lochmanová, Anna Panovská, Hana Skuhrová Francová, Marek Mráz, Boris Tichý, Ludmila Šebejová, Veronika Navrkalová, Karla Plevová, Petr Kuglík, Jiří Mayer & Šárka Pospíšilová
Pages: 1817-1819
Published online: 01 Mar 2012
First Page PreviewforSpecific p53 mutations do not impact results of alemtuzumab therapy among patients with chronic lymphocytic leukemia | Full Text | References | PDF (179.5 KB) | Supplemental
  • 116 Views
  • 3 CrossRef citations
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Letter
Phase II trial of the pan-deacetylase inhibitor panobinostat as a single agent in advanced relapsed/refractory multiple myeloma
Jeffrey L. Wolf, David Siegel, Hartmut Goldschmidt, Katharine Hazell, Priscille M. Bourquelot, Bourras R. Bengoudifa, Jeffrey Matous, Ravi Vij, Margarida de Magalhaes-Silverman, Rafat Abonour, Kenneth C. Anderson & Sagar Lonial
Pages: 1820-1823
Published online: 01 Mar 2012
First Page PreviewforPhase II trial of the pan-deacetylase inhibitor panobinostat as a single agent in advanced relapsed/refractory multiple myeloma | Full Text | References | PDF (212.8 KB) | Supplemental
  • 1435 Views
  • 102 CrossRef citations
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Letter
Chronic eosinophilic leukemia with erythroblastic proliferation and the rare translocation t(8;9)(p22;p24) with PCM1–JAK2 fusion gene: a distinct clinical, pathological and genetic entity with potential treatment target?
Monika Prochorec-Sobieszek, Barbara Nasiłowska-Adamska, Katarzyna Borg, Izabella Kopeć, Kinga Kos-Zakrzewska, Przemysław Juszczyński & Krzysztof Warzocha
Pages: 1824-1827
Published online: 13 Mar 2012
First Page PreviewforChronic eosinophilic leukemia with erythroblastic proliferation and the rare translocation t(8;9)(p22;p24) with PCM1–JAK2 fusion gene: a distinct clinical, pathological and genetic entity with potential treatment target? | Full Text | References | PDF (337.6 KB) | Supplemental
  • 260 Views
  • 9 CrossRef citations
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Letter
Variation in Toll-like receptor 9 gene modifies the risk of infection in children treated for acute lymphoblastic leukemia
Vivek A. Bhadri, Sara M. Beckett, Catriona Duncan, Glenn M. Marshall & Lesley J. Ashton
Pages: 1828-1830
Published online: 16 Mar 2012
First Page PreviewforVariation in Toll-like receptor 9 gene modifies the risk of infection in children treated for acute lymphoblastic leukemia | Full Text | References | PDF (148.4 KB) | Supplemental
  • 122 Views
  • 6 CrossRef citations
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Letter
Extranodal marginal zone lymphoma of the uterine corpus
Tanwen M. Wright, Simon Rule, Hongxiang Liu, Ming-Qing Du & Mark E. F. Smith
Pages: 1831-1834
Published online: 13 Mar 2012
First Page PreviewforExtranodal marginal zone lymphoma of the uterine corpus | Full Text | References | PDF (210.9 KB) | Supplemental
  • 114 Views
  • 5 CrossRef citations
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Letter
Chronic lymphocytic leukemia associated with immunotactoid glomerulopathy: a case report of successful treatment with high-dose methylprednisolone in combination with rituximab followed by alemtuzumab
Januario E. Castro, Julio A. Diaz-Perez, Juan S. Barajas-Gamboa, John M. Horton, Noel Weidner & Thomas J. Kipps
Pages: 1835-1838
Published online: 13 Mar 2012
First Page PreviewforChronic lymphocytic leukemia associated with immunotactoid glomerulopathy: a case report of successful treatment with high-dose methylprednisolone in combination with rituximab followed by alemtuzumab | Full Text | References | PDF (279.8 KB) | Supplemental
  • 206 Views
  • 8 CrossRef citations
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Letter
Acute lymphoblastic leukemia arising in post-polycythemic myelofibrosis: a rare entity
Maro Ohanian, Vasiliki Leventaki, Srdan Verstovsek, Zeev Estrov, Pei Lin, Cameron Yin, Hagop Kantarjian, Yang Huh & Farhad Ravandi
Pages: 1839-1841
Published online: 13 Mar 2012
First Page PreviewforAcute lymphoblastic leukemia arising in post-polycythemic myelofibrosis: a rare entity | Full Text | References | PDF (256.1 KB) | Supplemental
  • 170 Views
  • 8 CrossRef citations
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Letter
Thymidylate synthase polymorphisms and hematological cancer risk: evidence needs further clarification
Jue-Yu Zhou, Rong Shi, Hai-Lang Yu, Ye Zeng, Wen-Ling Zheng & Wen-Li Ma
Pages: 1842-1844
Published online: 13 Mar 2012
First Page PreviewforThymidylate synthase polymorphisms and hematological cancer risk: evidence needs further clarification | Full Text | References | PDF (139.2 KB) | Supplemental
  • 29 Views
  • 0 CrossRef citations
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Letter
Aggressive plasmablastic lymphoproliferation complicated by hemophagocytic syndrome 12 years after heart transplant
Anna-Kristina Reuland, Monika Engelhardt, Philipp T. Meyer, Anna Lena Stroh, Michael Lübbert, Jürgen Finke, Annette Schmitt-Gräff, Andreas Zirlik & Ralph Wäsch
Pages: 1845-1848
Published online: 16 Mar 2012
First Page PreviewforAggressive plasmablastic lymphoproliferation complicated by hemophagocytic syndrome 12 years after heart transplant | Full Text | References | PDF (306.1 KB) | Supplemental
  • 108 Views
  • 1 CrossRef citations
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