Leukemia & Lymphoma, Volume 60, Issue 10 (2019)

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Leukemia & Lymphoma, Volume 60, Issue 10 (2019)

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Commentaries

Article Commentary
Autologous hematopoetic cell transplantation: preferred consolidation treatment in low-risk AML?
Jakob R. Passweg
Pages: 2341-2342
Published online: 08 Apr 2019
CitationforAutologous hematopoetic cell transplantation: preferred consolidation treatment in low-risk AML? | Full Text | References | PDF (268.9 KB) | EPUB
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Article Commentary
Natural killer cell activity and survival after azacitidine treatment in high-risk MDS
Sameem M. Abedin & Leonidas C. Platanias
Pages: 2343-2344
Published online: 23 May 2019
CitationforNatural killer cell activity and survival after azacitidine treatment in high-risk MDS | Full Text | References | PDF (251.9 KB) | EPUB
  • 151 Views
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Article Commentary
It’s all about the CD3+ T-cells: how circulating immune cell subset analyses can predict early relapse in Hodgkin lymphoma
Jonathan Moreira, Leonidas C. Platanias & Kehinde U. A. Adekola
Pages: 2345-2347
Published online: 27 Aug 2019
First Page PreviewforIt’s all about the CD3+ T-cells: how circulating immune cell subset analyses can predict early relapse in Hodgkin lymphoma | Full Text | References | PDF (315.6 KB) | EPUB
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Reviews

Review
The importance of complex karyotype in prognostication and treatment of chronic lymphocytic leukemia (CLL): a comprehensive review of the literature
Marie Jarošová, Karla Plevová, Jana Kotašková, Michael Doubek & Šárka Pospíšilová
Pages: 2348-2355
Published online: 18 Feb 2019
AbstractforThe importance of complex karyotype in prognostication and treatment of chronic lymphocytic leukemia (CLL): a comprehensive review of the literature | Full Text | References | PDF (951.4 KB) | EPUB
  • 592 Views
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Review
Maximizing the effectiveness of oral therapies in lymphoid cancers: research gaps and unmet needs
Alix Y. L. Zackon, Amy A. Ayers, Katherine A. Yeager, Mary L. Somma, Jonathan W. Friedberg, Christopher R. Flowers & Loretta J. Nastoupil
Pages: 2356-2364
Published online: 04 Jun 2019
AbstractforMaximizing the effectiveness of oral therapies in lymphoid cancers: research gaps and unmet needs | Full Text | References | PDF (1 MB) | EPUB
  • 264 Views
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Review
Posterior reversible encephalopathy syndrome in pediatric patients: pathophysiology, diagnosis, and management
Michael G. Z. Ghali, Justin Davanzo, Madeline Leo & Elias Rizk
Pages: 2365-2372
Published online: 26 Sep 2019
AbstractforPosterior reversible encephalopathy syndrome in pediatric patients: pathophysiology, diagnosis, and management | Full Text | References | PDF (800.1 KB) | EPUB
  • 1319 Views
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Original Articles

Article
Auditing fungal disease in leukemia patients in a tertiary care center: opportunities and challenges for an antifungal stewardship program
Emma Paige, Peter Haywood, Mingdi Xie, Leon Worth, Karin Thursky, Karen Urbancic, Ashish Bajel & Monica Slavin
Pages: 2373-2383
Published online: 17 May 2019
AbstractforAuditing fungal disease in leukemia patients in a tertiary care center: opportunities and challenges for an antifungal stewardship program | Full Text | References | PDF (1.1 MB) | EPUB
  • 262 Views
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Article
Rates of deep molecular response by digital and conventional PCR with frontline nilotinib in newly diagnosed chronic myeloid leukemia: a landmark analysis
Jesus G. Berdeja, Michael C. Heinrich, Shaker R. Dakhil, Stuart L. Goldberg, Martha Wadleigh, Philip Kuriakose, Jorge Cortes, Jerald Radich, Bret Helton, David Rizzieri, Carole Paley, Ilva Dautaj & Michael J. Mauro
Pages: 2384-2393
Published online: 26 Mar 2019
AbstractforRates of deep molecular response by digital and conventional PCR with frontline nilotinib in newly diagnosed chronic myeloid leukemia: a landmark analysis | Full Text | References | PDF (1.6 MB) | EPUB | Supplemental
  • 2201 Views
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Open Access
Article
Predictors of early hemorrhage in acute promyelocytic leukemia
Leonard Naymagon, Erin Moshier, Douglas Tremblay & John Mascarenhas
Pages: 2394-2403
Published online: 08 Mar 2019
AbstractforPredictors of early hemorrhage in acute promyelocytic leukemia | Full Text | References | PDF (2.1 MB) | EPUB
  • 316 Views
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Article
A prospective non-interventional study on the impact of transfusion burden and related iron toxicity on outcome in myelodysplastic syndromes undergoing allogeneic hematopoietic cell transplantation
Eline M.P. Cremers, Theo de Witte, Liesbeth de Wreede, Diderik-Jan Eikema, Linda Koster, Anja van Biezen, Jürgen Finke, Gerard Socié, Dietrich Beelen, Johan Maertens, Arnon Nagler, Guido Kobbe, Dimitris Ziagkos, Maija Itälä-Remes, Tobias Gedde-Dahl, Jorge Sierra, Dietger Niederwieser, Per Ljungman, Yves Beguin, Zubeyde Nur Ozkurt, Achilles Anagnostopoulos, Pavel Jindra, Marie Robin & Nicolaus Kröger
Pages: 2404-2414
Published online: 18 Apr 2019
AbstractforA prospective non-interventional study on the impact of transfusion burden and related iron toxicity on outcome in myelodysplastic syndromes undergoing allogeneic hematopoietic cell transplantation | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
  • 1807 Views
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Open Access
Article
Variant allele frequencies do not correlate well with myeloblast counts in a clinically validated gene sequencing panel for routine acute myeloid leukemia workup
Laura N. Toth, Donald Green, Jason Peterson, Sophie J. Deharvengt, Francine B. de Abreu & Eric Y. Loo
Pages: 2415-2422
Published online: 18 Apr 2019
AbstractforVariant allele frequencies do not correlate well with myeloblast counts in a clinically validated gene sequencing panel for routine acute myeloid leukemia workup | Full Text | References | PDF (911.3 KB) | EPUB | Supplemental
  • 309 Views
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Article
Improved survival rates of AML patients following admission to the intensive care unit
Priska Fassbind, Barbara Jeker, Beatrice U. Mueller, Ulrike Bacher, Stefan Zimmerli, Olga Endrich, Brigitta Gahl, Urban Novak & Thomas Pabst
Pages: 2423-2431
Published online: 03 Apr 2019
AbstractforImproved survival rates of AML patients following admission to the intensive care unit | Full Text | References | PDF (825.3 KB) | EPUB | Supplemental
  • 202 Views
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Article
Limited stage grade 3 follicular lymphoma patients can experience favorable outcomes with combined modality therapy
Zeina Ayoub, Therese Andraos, Sarah A. Milgrom, Chelsea C. Pinnix, Bouthaina S. Dabaja, Sweet Ping Ng, Jillian R. Gunther, Joseph D. Khoury, Nathan H. Fowler, Satva S. Neelapu, Felipe Samaniego, Luis E. Fayad & Loretta J. Nastoupil
Pages: 2432-2440
Published online: 03 Apr 2019
AbstractforLimited stage grade 3 follicular lymphoma patients can experience favorable outcomes with combined modality therapy | Full Text | References | PDF (1.2 MB) | EPUB
  • 210 Views
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Article
Procalcitonin as a marker of Gram-negative bloodstream infections in hematological patients with febrile neutropenia
Xiaofeng Luo, Shaozhen Chen, Jingxi Zhang, Jinhua Ren, Minmin Chen, Kangni Lin, Haojie Zhu, Rong Zheng, Zhihong Zheng, Zhizhe Chen, Jianda Hu & Ting Yang
Pages: 2441-2448
Published online: 26 Feb 2019
AbstractforProcalcitonin as a marker of Gram-negative bloodstream infections in hematological patients with febrile neutropenia | Full Text | References | PDF (933.6 KB) | EPUB | Supplemental
  • 276 Views
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Article
Superior outcome of patients with favorable-risk acute myeloid leukemia using consolidation with autologous stem cell transplantation
Ofrat Beyar-Katz, Noa Lavi, Shimrit Ringelstein-Harlev, Israel Henig, Dana Yehudai-Ofir, Nuhad Haddad, Riva Fineman, Yishai Ofran, Yuval Nov, Dvora Sahar, Nivin Moustafa-Hawash, Jacob M. Rowe & Tsila Zuckerman
Pages: 2449-2456
Published online: 03 Apr 2019
AbstractforSuperior outcome of patients with favorable-risk acute myeloid leukemia using consolidation with autologous stem cell transplantation | Full Text | References | PDF (908.8 KB) | EPUB
  • 394 Views
  • 11 CrossRef citations
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Article
Natural killer cell cytotoxicity is a predictor of outcome for patients with high risk myelodysplastic syndrome and oligoblastic acute myeloid leukemia treated with azacytidine
Maria Tsirogianni, Eirini Grigoriou, Violetta Kapsimalli, Kleopatra Dagla, Maria Stamouli, Konstantinos Gkirkas, Eve Konsta, Angeliki Karagiannidou, Konstantinos Gkodopoulos, Georgia Stavroulaki, Vassiliki Pappa, Maria Angelopoulou, Mark Lowdell & Panagiotis Tsirigotis
Pages: 2457-2463
Published online: 05 Apr 2019
AbstractforNatural killer cell cytotoxicity is a predictor of outcome for patients with high risk myelodysplastic syndrome and oligoblastic acute myeloid leukemia treated with azacytidine | Full Text | References | PDF (923.4 KB) | EPUB | Supplemental
  • 360 Views
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Article
Complications and hospital costs during hematopoietic stem cell transplantation for non-Hodgkin lymphoma in the United States
Sang Kyu Cho, Jeffrey McCombs, Nathan Punwani & Jenny Lam
Pages: 2464-2470
Published online: 08 Mar 2019
AbstractforComplications and hospital costs during hematopoietic stem cell transplantation for non-Hodgkin lymphoma in the United States | Full Text | References | PDF (705 KB) | EPUB | Supplemental
  • 388 Views
  • 7 CrossRef citations
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Article
FDG-PET/CT in managing infection in patients with hematological malignancy: clinician knowledge and experience in Australia
Abby P. Douglas, Karin A. Thursky, Leon J. Worth, Simon James Harrison, Rod John Hicks & Monica A. Slavin
Pages: 2471-2476
Published online: 05 Apr 2019
AbstractforFDG-PET/CT in managing infection in patients with hematological malignancy: clinician knowledge and experience in Australia | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 161 Views
  • 4 CrossRef citations
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Article
The prognostic significance of bone marrow involvement in diffuse large B cell lymphoma according to the flow cytometry
Uri Greenbaum, Itai Levi, Odelia Madmoni, Yotam Lior, Kayed Al-Athamen, Zvi Howard Perry, Lev Hatzkelzon & George Shubinsky
Pages: 2477-2482
Published online: 24 Apr 2019
AbstractforThe prognostic significance of bone marrow involvement in diffuse large B cell lymphoma according to the flow cytometry | Full Text | References | PDF (847.3 KB) | EPUB | Supplemental
  • 227 Views
  • 8 CrossRef citations
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Article
Clinical outcome of patients diagnosed with myelodysplastic syndrome-unclassifiable (MDS-U): single center experience
Firas Baidoun, Dong Chen, Mrinal Patnaik, Naseema Gangat, Kebede Begna, Michelle Elliott, William Hogan, Mark Litzow & Aref Al-Kali
Pages: 2483-2487
Published online: 07 Mar 2019
AbstractforClinical outcome of patients diagnosed with myelodysplastic syndrome-unclassifiable (MDS-U): single center experience | Full Text | References | PDF (1 MB) | EPUB
  • 153 Views
  • 3 CrossRef citations
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Article
Increased circulating CD3+ T cells are associated with early relapse following autologous hematopoietic stem cell transplantation in patients with classical Hodgkin lymphoma
Egor V. Batorov, Natalia V. Pronkina, Marina A. Tikhonova, Irina V. Kryuchkova, Vera V. Sergeevicheva, Svetlana A. Sizikova, Galina Y. Ushakova, Tatiana A. Aristova, Dariya S. Batorova, Irina V. Shishkova, Andrey V. Gilevich, Ekaterina Y. Shevela, Alexander A. Ostanin & Elena R. Chernykh
Pages: 2488-2497
Published online: 11 Mar 2019
AbstractforIncreased circulating CD3+ T cells are associated with early relapse following autologous hematopoietic stem cell transplantation in patients with classical Hodgkin lymphoma | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 198 Views
  • 2 CrossRef citations
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Article
Modulation of immune checkpoint molecule expression in mantle cell lymphoma
Bonnie K. Harrington, Esther Wheeler, Kasey Hornbuckle, Arwa Y. Shana’ah, Youssef Youssef, Lisa Smith, Quais Hassan II, Brett Klamer, Xiaoli Zhang, Meixiao Long, Robert A. Baiocchi, Kami Maddocks, Amy J. Johnson, John C. Byrd & Lapo Alinari
Pages: 2498-2507
Published online: 01 Mar 2019
AbstractforModulation of immune checkpoint molecule expression in mantle cell lymphoma | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 662 Views
  • 17 CrossRef citations
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Article
Clinicopathological features of clinical methotrexate-related lymphoproliferative disorders
Michihide Tokuhira, Shuntaro Saito, Katsuya Suzuki, Morihiro Higashi, Shuju Momose, Takayuki Shimizu, Takehiko Mori, Yuta Kimura, Koichi Amano, Shinichiro Okamoto, Tsutomu Takeuchi, Jun-Ichi Tamaru & Masahiro Kizaki
Pages: 2508-2515
Published online: 05 Apr 2019
AbstractforClinicopathological features of clinical methotrexate-related lymphoproliferative disorders | Full Text | References | PDF (893.2 KB) | EPUB
  • 347 Views
  • 6 CrossRef citations
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Article
Risk of death, relapse or progression, and loss of life expectancy at different progression-free survival milestones in primary central nervous system lymphoma
Jorne L. Biccler, Kerry J. Savage, Peter D.N. Brown, Judit Jørgensen, Thomas S. Larsen, Christian B. Poulsen, Danny Stoltenberg, Laurie H. Sehn, David W. Scott, Alina S. Gerrie, Lasse H. Jakobsen, Martin Bøgsted, Tarec C. El-Galaly & Diego Villa
Pages: 2516-2523
Published online: 03 Apr 2019
AbstractforRisk of death, relapse or progression, and loss of life expectancy at different progression-free survival milestones in primary central nervous system lymphoma | Full Text | References | PDF (938.8 KB) | EPUB | Supplemental
  • 330 Views
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Article
Refractoriness to rituximab-based therapy and elevated serum B2-microglobulin predict for inferior survival in marginal zone lymphoma
Marc Sorigue, Mark Bishton, Eva Domingo-Domenech, Andrew McMillan, Roosa Prusila, Olga García, Milla Kuusisto, Maria Condom, Gustavo Tapia, Josep-María Ribera, Outi Kuittinen, Christopher P. Fox & Juan-Manuel Sancho
Pages: 2524-2531
Published online: 03 Apr 2019
AbstractforRefractoriness to rituximab-based therapy and elevated serum B2-microglobulin predict for inferior survival in marginal zone lymphoma | Full Text | References | PDF (973.8 KB) | EPUB | Supplemental
  • 206 Views
  • 3 CrossRef citations
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Article
ERK-dependent IL-6 positive feedback loop mediates resistance against a combined treatment using danusertib and BKM120 in Burkitt lymphoma cell lines
Jun Liu, Junshik Hong, Kwang-Sung Ahn, Junhyeok Go, Heejoo Han, Jihyun Park, Dongchan Kim, Hyejoo Park, Youngil Koh, Dong-Yeop Shin & Sung-Soo Yoon
Pages: 2532-2540
Published online: 05 Apr 2019
AbstractforERK-dependent IL-6 positive feedback loop mediates resistance against a combined treatment using danusertib and BKM120 in Burkitt lymphoma cell lines | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 485 Views
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Article
Loc108167440 suppressed myeloma cell growth by P53-mediated apoptosis
Bing Zhai, Chunmei Hou, Ruonan Xu, Ying Fang, He Xiao, Guojiang Chen, Xiaoqian Wang, Ning Ma, Gencheng Han & Renxi Wang
Pages: 2541-2548
Published online: 05 Apr 2019
AbstractforLoc108167440 suppressed myeloma cell growth by P53-mediated apoptosis | Full Text | References | PDF (1.7 MB) | EPUB
  • 90 Views
  • 6 CrossRef citations
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Article
Ruxolitinib treatment reduces monocytic superoxide radical formation without affecting hydrogen peroxide formation or systemic oxidative nucleoside damage in myelofibrosis
Mads Emil Bjørn, Marie Klinge Brimnes, Sif Gudbrandsdottir, Christen Lykkegaard Andersen, Henrik Enghusen Poulsen, Trine Henriksen, Hans Carl Hasselbalch & Claus Henrik Nielsen
Pages: 2549-2557
Published online: 20 Feb 2019
AbstractforRuxolitinib treatment reduces monocytic superoxide radical formation without affecting hydrogen peroxide formation or systemic oxidative nucleoside damage in myelofibrosis | Full Text | References | PDF (2.3 MB) | EPUB
  • 240 Views
  • 5 CrossRef citations
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Letters to the Editor

Letter
Versican proteolysis predicts immune effector infiltration and post-transplant survival in myeloma
Binod Dhakal, Adam Pagenkopf, Muhammad Umair Mushtaq, Ashley M. Cunningham, Evan Flietner, Zachary Morrow, Athanasios Papadas, Chelsea Hope, Catherine Leith, Peiman Hematti, Parameswaran Hari, Natalie S. Callander & Fotis Asimakopoulos
Pages: 2558-2562
Published online: 08 Mar 2019
First Page PreviewforVersican proteolysis predicts immune effector infiltration and post-transplant survival in myeloma | Full Text | References | PDF (902.7 KB) | EPUB
  • 344 Views
  • 12 CrossRef citations
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Letter
High serum levels of CD178 (soluble FasL) predict for inferior progression free survival in chronic lymphocytic leukemia treated with fludarabine-based chemotherapy
Courtney Tate, Melinda Burgess, Nigel A. McMillan, Nicholas A. Saunders, Catherine Cheung, Devinder Gill & Peter Mollee
Pages: 2563-2567
Published online: 25 Jun 2019
First Page PreviewforHigh serum levels of CD178 (soluble FasL) predict for inferior progression free survival in chronic lymphocytic leukemia treated with fludarabine-based chemotherapy | Full Text | References | PDF (780.3 KB) | EPUB
  • 120 Views
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Letter
A novel germline RUNX1 mutation with co-occurrence of somatic alterations in a case of myeloid neoplasm with familial thrombocytopenia: first report from India
Sweta Rajpal, Arihant Jain, Manu Jamwal, Nidhi Jain, Man U. S. Sachdeva, Pankaj Malhotra, Neelam Varma & Reena Das
Pages: 2568-2571
Published online: 16 Apr 2019
First Page PreviewforA novel germline RUNX1 mutation with co-occurrence of somatic alterations in a case of myeloid neoplasm with familial thrombocytopenia: first report from India | Full Text | References | PDF (872.1 KB) | EPUB
  • 193 Views
  • 2 CrossRef citations
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Letter
The challenge of myeloma-related thromboembolic disease: can thrombin generation assay help physicians to better predict the thromboembolic risk and personalize anti-thrombotic prophylaxis?
Yesim Dargaud, Marc Fouassier, Jean Claude Bordet, Sophie Ducastelle-Lepretre, Charles Dumontet, Philippe Moreau & Mauricette Michallet
Pages: 2572-2575
Published online: 03 Apr 2019
First Page PreviewforThe challenge of myeloma-related thromboembolic disease: can thrombin generation assay help physicians to better predict the thromboembolic risk and personalize anti-thrombotic prophylaxis? | Full Text | References | PDF (691.1 KB) | EPUB
  • 155 Views
  • 4 CrossRef citations
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Letter
Outcomes of patients with relapsed low-grade lymphoma retreated with rituximab are similar to rituximab naïve patients
Abi Vijenthira, Manjula Maganti, Vishal Kukreti, John Kuruvilla, Rodger Tiedemann, Christine Chen, Michael Crump & Anca Prica
Pages: 2576-2579
Published online: 18 Apr 2019
First Page PreviewforOutcomes of patients with relapsed low-grade lymphoma retreated with rituximab are similar to rituximab naïve patients | Full Text | References | PDF (609.5 KB) | EPUB
  • 118 Views
  • 0 CrossRef citations
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Letter
Perceived risk for cancer progression and psychological status in chronic lymphocytic leukemia patients: CALGB 70603 (Alliance)
Teresa L. Deshields, Amylou C. Dueck, Kerry Rogers, Jennifer R. Brown, Tait Shanafelt, David Mintzer & John C. Byrd
Pages: 2580-2583
Published online: 27 Mar 2019
First Page PreviewforPerceived risk for cancer progression and psychological status in chronic lymphocytic leukemia patients: CALGB 70603 (Alliance) | Full Text | References | PDF (403.1 KB) | EPUB
  • 216 Views
  • 0 CrossRef citations
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Letter
Allogeneic stem cell transplantation and combination antiretroviral therapy: cautions, complications, and considerations
Rory M. Shallis, Shana Gleeson, Marwan M. Azar, Maricar Malinis, Mina L. Xu, Stuart E. Seropian, Lohith Gowda & Amer M. Zeidan
Pages: 2584-2587
Published online: 03 Apr 2019
First Page PreviewforAllogeneic stem cell transplantation and combination antiretroviral therapy: cautions, complications, and considerations | Full Text | References | PDF (1.4 MB) | EPUB
  • 190 Views
  • 1 CrossRef citations
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Letter
Clinical value of molecular MRD monitoring by next-generation sequencing in patients with IDH2 mutated AML
Evgenii Shumilov, Johanna Flach, Raphael Joncourt, Naomi Porret, Gertrud Wiedemann, Urban Novak, Eva Gfeller, Barbara Jeker, Ursula Amstutz, Thomas Pabst & Ulrike Bacher
Pages: 2588-2590
Published online: 18 Apr 2019
First Page PreviewforClinical value of molecular MRD monitoring by next-generation sequencing in patients with IDH2 mutated AML | Full Text | References | PDF (432.8 KB) | EPUB
  • 238 Views
  • 2 CrossRef citations
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Letter
Comprehensive molecular characterization of myeloid malignancies with 9q deletion
Luise Hartmann, Torsten Haferlach, Manja Meggendorfer, Wolfgang Kern, Claudia Haferlach & Anna Stengel
Pages: 2591-2593
Published online: 07 Mar 2019
First Page PreviewforComprehensive molecular characterization of myeloid malignancies with 9q deletion | Full Text | References | PDF (827.9 KB) | EPUB
  • 147 Views
  • 2 CrossRef citations
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Letter
Autoantibodies in myelodysplastic syndromes and chronic myelomonocytic leukemia
Jean-Baptiste Fraison, Eric Grignano, Thorsten Braun, Lionel Adès, Sylvie Chollet-Martin, Pascale Roland-Nicaise, Pierre Fenaux, Olivier Fain & Arsène Mekinian
Pages: 2594-2596
Published online: 08 Apr 2019
First Page PreviewforAutoantibodies in myelodysplastic syndromes and chronic myelomonocytic leukemia | Full Text | References | PDF (298.7 KB) | EPUB
  • 197 Views
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