Xenobiotica, Volume 27, Issue 10 (1997)

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Xenobiotica, Volume 27, Issue 10 (1997)

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Research Article

Article
Identification of cytochrome P4503A as the major enzyme sub-family responsible for the metabolism of 22,23-dihydro-13-O-[(2-methoxyethoxy)methyl]avermectin B1 aglycone by rat liver microsomes
Z. ZENG*N. W. ANDREW & B. A. HALLEY
Pages: 985-994
Published online: 22 Sep 2008
AbstractforIdentification of cytochrome P4503A as the major enzyme sub-family responsible for the metabolism of 22,23-dihydro-13-O-[(2-methoxyethoxy)methyl]avermectin B1 aglycone by rat liver microsomes | References | PDF (219.8 KB)
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Article
N-oxidation of irsogladine by the CYP2C subfamily in the rat, dog, monkey and man
A. NAKAMURA*T. HIROTA, A. MORINO, T. SHIMADA & T. UEMATSU
Pages: 995-1003
Published online: 22 Sep 2008
AbstractforN-oxidation of irsogladine by the CYP2C subfamily in the rat, dog, monkey and man | References | PDF (167 KB)
  • 51 Views
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Article
Localization, depuration, bioaccumulation and impairment of ion regulation associated with cationic polymer exposure in rainbow trout (Oncorhynchus mykiss)
M. M. MUIR, K. G. KOSTERETZ & J. J. LECH*
Pages: 1005-1014
Published online: 22 Sep 2008
AbstractforLocalization, depuration, bioaccumulation and impairment of ion regulation associated with cationic polymer exposure in rainbow trout (Oncorhynchus mykiss) | References | PDF (179.4 KB)
  • 85 Views
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Article
Rifampin and rifabutin and their metabolism by human liver esterases
C. A. JAMIS-DOW, A. G. KATKI, J. M. COLLINS & R. W. KLECKER*
Pages: 1015-1024
Published online: 22 Sep 2008
AbstractforRifampin and rifabutin and their metabolism by human liver esterases | References | PDF (189 KB)
  • 407 Views
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Article
Identification of the cytochrome P450 isoforms involved in the O-demethylation of 4-nitroanisole in human liver microsomes
B. C. JONES*C. A. TYMAN & D. A. SMITH
Pages: 1025-1037
Published online: 22 Sep 2008
AbstractforIdentification of the cytochrome P450 isoforms involved in the O-demethylation of 4-nitroanisole in human liver microsomes | References | PDF (267.4 KB)
  • 203 Views
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Article
Metabolism of a bisphosphonate ester (PNU-91638) in rat
J. G. SLATTER*K. L. FEENSTRA, M. J. HAUER, P. E. SANDERS, J. J. VRBANAC, G. SCOTT & W. SPEED
Pages: 1039-1051
Published online: 22 Sep 2008
AbstractforMetabolism of a bisphosphonate ester (PNU-91638) in rat | References | PDF (299.4 KB)
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Article
Absorption, distribution, metabolism and excretion of a new, 14C-labelled oxazolidinone MAO-A inhibitor in rat and dog
T. NAITOH*M. MISHIMA, S. KAWAGUCHI, K. MATSUI, T. ANDOH, K. KAGEI, M. KAKIKI, T. YUZURIHA & T. HORIE
Pages: 1053-1070
Published online: 22 Sep 2008
AbstractforAbsorption, distribution, metabolism and excretion of a new, 14C-labelled oxazolidinone MAO-A inhibitor in rat and dog | References | PDF (281.4 KB)
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Article
Identification of the metabolites of a new oxazolidinone MAO-A inhibitor in rat
T. NAITOH*M. KAKIKI, T. KOZAKI, M. MISHIMA, T. YUZURIHA & T. HORIE
Pages: 1071-1089
Published online: 22 Sep 2008
AbstractforIdentification of the metabolites of a new oxazolidinone MAO-A inhibitor in rat | References | PDF (295 KB)
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Article
Formation and pharmacokinetics of the active drug candoxatrilat in mouse, rat, rabbit, dog and man following administration of the prodrug candoxatril
B. KAYE*C. J. BREARLEY, N. J. CUSSANS, M. HERRON, M. J. HUMPHREY & A. R. MOLLATT
Pages: 1091-1102
Published online: 22 Sep 2008
AbstractforFormation and pharmacokinetics of the active drug candoxatrilat in mouse, rat, rabbit, dog and man following administration of the prodrug candoxatril | References | PDF (232.7 KB)
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