Xenobiotica, Volume 27, Issue 6 (1997)

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Xenobiotica, Volume 27, Issue 6 (1997)

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Research Article

Article
Metabolism of the calcium antagonist, mibefradil (POSICOR™, Ro 40-5967). Part II. Metabolism in hepatic microsomes from rat, marmoset, cynomolgus monkey, rabbit and man
H. R. WILTSHIRE*B. M. SUTTON, G. HEEPS, A. M. BETTY, D. W. ANGUS, M. J. MADIGAN & S. R. SHARP
Pages: 539-556
Published online: 22 Sep 2008
AbstractforMetabolism of the calcium antagonist, mibefradil (POSICOR™, Ro 40-5967). Part II. Metabolism in hepatic microsomes from rat, marmoset, cynomolgus monkey, rabbit and man | References | PDF (348.8 KB)
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Article
Metabolism of the calcium antagonist, mibefradil (POSICORTM, Ro 40-5967). Part III. Comparative pharmacokinetics of mibefradil and its major metabolites in rat, marmoset, cynomolgus monkey and man
H. R. WILTSHIRE, B. M. SUTTON, G. HEEPS, A. M. BETTY, D. W. ANGUS, S. R. HARRIS, E. WORTH & H. A. WELKER
Pages: 557-571
Published online: 22 Sep 2008
AbstractforMetabolism of the calcium antagonist, mibefradil (POSICORTM, Ro 40-5967). Part III. Comparative pharmacokinetics of mibefradil and its major metabolites in rat, marmoset, cynomolgus monkey and man | References | PDF (306.5 KB)
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Article
Purification and characterization of hepatic glutathione transferases from an insectivorous marsupial, the brown antechinus (Antechinus stuartii)
R. M. BOLTON & J. T. AHOKAS*
Pages: 573-586
Published online: 22 Sep 2008
AbstractforPurification and characterization of hepatic glutathione transferases from an insectivorous marsupial, the brown antechinus (Antechinus stuartii) | References | PDF (276.3 KB)
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Article
The isoflavones equol and genistein do not induce xenobiotic-metabolizing enzymes in mouse and in human cells
N. A. HELSBY, J. WILLIAMS, D. KERR, A. GESCHER & J. K. CHIPMAN*
Pages: 587-596
Published online: 22 Sep 2008
AbstractforThe isoflavones equol and genistein do not induce xenobiotic-metabolizing enzymes in mouse and in human cells | References | PDF (223.9 KB)
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Article
Absorption, metabolism and excretion after oral administration of a new Ca antagonist, 14C-benidipine hydrochloride to man
H. KOBAYASHI*S. KOBAYASHI & P. D. DALRYMPLE
Pages: 597-608
Published online: 22 Sep 2008
AbstractforAbsorption, metabolism and excretion after oral administration of a new Ca antagonist, 14C-benidipine hydrochloride to man | References | PDF (227.1 KB)
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Article
Pharmacokinetics of 2-naphthol following intrapericardial administration, and formation of 2-naphthyl- beta --glucoside and 2-naphthyl sulphate D in the American lobster, Homarus americanus
C.-L. J. LI & M. O. JAMES*
Pages: 609-626
Published online: 22 Sep 2008
AbstractforPharmacokinetics of 2-naphthol following intrapericardial administration, and formation of 2-naphthyl- beta --glucoside and 2-naphthyl sulphate D in the American lobster, Homarus americanus | References | PDF (297.4 KB)
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Article
Intraperitoneal and intraportal administration of droloxifene to the Sprague-Dawley rat: assessing the first-pass effect
D. F. NICKERSON & S. M. TOLER*
Pages: 627-632
Published online: 22 Sep 2008
AbstractforIntraperitoneal and intraportal administration of droloxifene to the Sprague-Dawley rat: assessing the first-pass effect | References | PDF (130.9 KB)
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