Xenobiotica, Volume 33, Issue 5 (2003)

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Xenobiotica, Volume 33, Issue 5 (2003)

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Research Article

Article
Constitutive and inducible expression of CYP enzymes in immortal hepatocytes derived from SV40 transgenic mice
M. T. Donato, R. Klocke, J. V. Castell, K. Stenzel, D. Paul & M. J. Gómez-Lechón
Pages: 459-473
Published online: 22 Sep 2008
AbstractforConstitutive and inducible expression of CYP enzymes in immortal hepatocytes derived from SV40 transgenic mice | References | PDF (317.9 KB)
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Article
Prediction of in vivo hepatic clearance from in vitro data using cryopreserved human hepatocytes
K. Bachmann, J. Byers & R. Ghosh
Pages: 475-483
Published online: 22 Sep 2008
AbstractforPrediction of in vivo hepatic clearance from in vitro data using cryopreserved human hepatocytes | References | PDF (195 KB)
  • 256 Views
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Article
Phase II in vitro metabolism of 3-methylindole metabolites in porcine liver
G. J. Diaz & E. J. Squires
Pages: 485-498
Published online: 22 Sep 2008
AbstractforPhase II in vitro metabolism of 3-methylindole metabolites in porcine liver | References | PDF (243 KB)
  • 123 Views
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Article
Identification of novel metabolites of pioglitazone in rat and dog
Z. Shen, J. R. Reed, M. Creighton, D. Q. Liu, Y. S. Tang, D. F. Hora, W. Feeney, J. Szewczyk, R. Bakhtiar, R. B. Franklin & S. H. Vincent
Pages: 499-509
Published online: 22 Sep 2008
AbstractforIdentification of novel metabolites of pioglitazone in rat and dog | References | PDF (364.4 KB)
  • 190 Views
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Article
Studies on the induction of rat hepatic CYP1A, CYP2B, CYP3A and CYP4A subfamily form mRNAs in vivo and in vitro using precision-cut rat liver slices
C. Meredith, M. P. Scott, A. B. Renwick, R. J. Price & B. G. Lake
Pages: 511-527
Published online: 22 Sep 2008
AbstractforStudies on the induction of rat hepatic CYP1A, CYP2B, CYP3A and CYP4A subfamily form mRNAs in vivo and in vitro using precision-cut rat liver slices | References | PDF (353.2 KB)
  • 379 Views
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Article
More potent inhibition of human CYP2A6 than mouse CYP2A5 enzyme activities by derivatives of phenylethylamine and benzaldehyde
M. Rahnasto, H. Raunio, A. Poso & R. O. Juvonen
Pages: 529-539
Published online: 22 Sep 2008
AbstractforMore potent inhibition of human CYP2A6 than mouse CYP2A5 enzyme activities by derivatives of phenylethylamine and benzaldehyde | References | PDF (165.1 KB)
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Article
Pharmacokinetics and disposition of a novel NMDA glycine site antagonist (UK-240,455) in rats, dogs and man
R. Webster, S. Cole, J. Gedge, S. Roffey, D. Walker & W. Wild
Pages: 541-560
Published online: 22 Sep 2008
AbstractforPharmacokinetics and disposition of a novel NMDA glycine site antagonist (UK-240,455) in rats, dogs and man | References | PDF (332.5 KB)
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Article
Identification of coenzyme A-related tolmetin metabolites in rats: relationship with reactive drug metabolites
J. Olsen, I. Bjørnsdottir & S. Honorè Hansen
Pages: 561-570
Published online: 22 Sep 2008
AbstractforIdentification of coenzyme A-related tolmetin metabolites in rats: relationship with reactive drug metabolites | References | PDF (213.3 KB)
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